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Gene: Atf2 (activating transcription factor 2) Mus musculus
Symbol: Atf2
Name: activating transcription factor 2
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; chromatin binding activity; and sequence-specific DNA binding activity. Involved in several processes, including adipose tissue development; fat cell differentiation; and positive regulation of transforming growth factor beta2 production. Localizes to the membrane; nucleus; and site of double-strand break. Used to study meconium aspiration syndrome and osteochondrodysplasia. Is expressed in several structures, including central nervous system; early conceptus; reproductive system; retina; and urinary system. Orthologous to human ATF2 (activating transcription factor 2); PARTICIPATES IN adenosine signaling pathway; interleukin-12 signaling pathway; influenza A pathway; INTERACTS WITH (-)-anisomycin; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Atf-2; cAMP response element-binding protein CRE-BP1; cAMP-dependent transcription factor ATF-2; CRE-BP; Creb2; cyclic AMP-dependent transcription factor ATF-2; D130078H02Rik; D18875; MGC105211; MGC105222; mXBP; Tg(Gzma-Klra1)7Wum
Homo sapiens (human) : ATF2 (activating transcription factor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Atf2 (activating transcription factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atf2 (activating transcription factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ATF2 (activating transcription factor 2)
Canis lupus familiaris (dog) : ATF2 (activating transcription factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atf2 (activating transcription factor 2)
Sus scrofa (pig) : ATF2 (activating transcription factor 2)
Chlorocebus sabaeus (green monkey) : ATF2 (activating transcription factor 2)
Heterocephalus glaber (naked mole-rat) : Atf2 (activating transcription factor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl273,816,509 - 73,892,639 (-)Ensembl
GRCm38273,816,509 - 73,892,677 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37273,654,578 - 73,730,685 (-)NCBIGRCm37mm9NCBIm37
MGSCv36273,617,360 - 73,693,467 (-)NCBImm8
Celera275,503,531 - 75,579,505 (-)NCBICelera
Cytogenetic Map2 C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Atf2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736761
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.