GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Atf2 | increases expression | EXP | | 6480464 | CTD | sodium arsenite results in increased expression of ATF2 protein modified form | PMID:16797887 | Atf2 | multiple interactions | EXP | | 6480464 | CTD | sodium arsenite promotes the reaction [[[ATF2 protein binds to ATF2 protein] which binds to PCK1 promoter] which results in increased expression of PCK1 mRNA] | PMID:9712902 | Atf2 | decreases expression | ISO | ATF2 (Homo sapiens) | 6480464 | CTD | sodium arsenite results in decreased expression of ATF2 mRNA | PMID:28595984 PMID:34032870 | Atf2 | increases activity | ISO | ATF2 (Homo sapiens) | 6480464 | CTD | sodium arsenite results in increased activity of ATF2 protein | PMID:12220541 PMID:15292961 | Atf2 | increases expression | ISO | ATF2 (Homo sapiens) | 6480464 | CTD | sodium arsenite results in increased expression of ATF2 mRNA; sodium arsenite results in increased expression of ATF2 protein; sodium arsenite results in increased expression of ATF2 protein modified form | PMID:12016162 PMID:17879257 PMID:23591579 PMID:30090515 | Atf2 | increases phosphorylation | ISO | ATF2 (Homo sapiens) | 6480464 | CTD | sodium arsenite results in increased phosphorylation of ATF2 protein | PMID:9728050 | Atf2 | increases phosphorylation | ISO | Atf2 (Mus musculus) | 6480464 | CTD | sodium arsenite results in increased phosphorylation of ATF2 protein | PMID:11807808 | Atf2 | multiple interactions | ISO | ATF2 (Homo sapiens) | 6480464 | CTD | ATF2 protein inhibits the reaction [sodium arsenite results in increased expression of CXCL8 mRNA]; ATF2 protein inhibits the reaction [sodium arsenite results in increased expression of TNF mRNA]; ATF2 protein promotes the reaction [sodium arsenite results in increased expression of BCL2 protein]; ATF2 protein promotes the reaction [sodium arsenite results in increased expression of CCND1 mRNA]; ATF2 protein promotes the reaction [sodium arsenite results in increased expression of CCND1 protein]; ATF2 protein promotes the reaction [sodium arsenite results in increased expression of MMP1 mRNA]; ATF2 protein promotes the reaction [sodium arsenite results in increased expression of PCNA mRNA]; ATF2 protein promotes the reaction [sodium arsenite results in increased expression of PCNA protein]; ATF2 protein promotes the reaction [sodium arsenite results in increased expression of PTGS2 protein]; Melatonin inhibits the reaction [sodium arsenite results in increased expression of ATF2 mRNA]; Melatonin inhibits the reaction [sodium arsenite results in increased expression of ATF2 protein modified form]; Melatonin inhibits the reaction [sodium arsenite results in increased expression of ATF2 protein]; pyrazolanthrone inhibits the reaction [sodium arsenite results in increased expression of ATF2 mRNA]; pyrazolanthrone inhibits the reaction [sodium arsenite results in increased expression of ATF2 protein modified form]; pyrazolanthrone inhibits the reaction [sodium arsenite results in increased expression of ATF2 protein]; SB 203580 inhibits the reaction [sodium arsenite results in increased expression of ATF2 mRNA]; SB 203580 inhibits the reaction [sodium arsenite results in increased expression of ATF2 protein modified form]; SB 203580 inhibits the reaction [sodium arsenite results in increased expression of ATF2 protein] | PMID:23591579 PMID:30090515 | |
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