Jun (Jun proto-oncogene, AP-1 transcription factor subunit)

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Gene: Jun (Jun proto-oncogene, AP-1 transcription factor subunit) Rattus norvegicus

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Symbol:

Jun

Name:

Jun proto-oncogene, AP-1 transcription factor subunit

RGD ID:

2943

Description:

Enables several functions, including DNA binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and HMG box domain binding activity. Involved in several processes, including cellular response to potassium ion starvation; positive regulation of nucleobase-containing compound metabolic process; and response to peptide hormone. Part of chromatin. Used to study hypertension. Biomarker of depressive disorder and renal carcinoma. Human ortholog(s) of this gene implicated in pulmonary tuberculosis. Orthologous to human JUN (Jun proto-oncogene, AP-1 transcription factor subunit); PARTICIPATES IN Rho/Rac/Cdc42 mediated signaling pathway; adenosine signaling pathway; endothelin signaling pathway; INTERACTS WITH (+)-pilocarpine; (-)-anisomycin; (R)-lipoic acid.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

activator protein 1; AP1; Avian sarcoma virus 17 (v-jun) oncogene homolog; Jun oncogene; jun proto-oncogene; proto-oncogene c-jun; transcription factor AP-1; transcription factor AP-1 subunit Jun; transcription factor Jun; V-jun avian sarcoma virus 17 oncogene homolog; v-jun sarcoma virus 17 oncogene homolog; v-jun sarcoma virus 17 oncogene homolog (avian)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Candidate Gene For:

Ciaa5

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	115,009,900 - 115,012,993 (-)	NCBI		GRCr8
mRatBN7.2	5	109,894,175 - 109,897,268 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	109,893,145 - 109,897,656 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	112,464,752 - 112,467,841 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	114,190,270 - 114,193,359 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	114,252,804 - 114,255,893 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	114,011,184 - 114,014,277 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	114,011,189 - 114,014,277 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	117,957,730 - 117,960,823 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	115,358,166 - 115,361,259 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	115,363,396 - 115,365,980 (-)	NCBI
Celera	5	108,510,040 - 108,513,133 (-)	NCBI		Celera
Cytogenetic Map	5	q33	NCBI

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Model

Annotation Click to see Annotation Detail View

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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