Gene: P2rx3 (purinergic receptor P2X 3) Rattus norvegicus
Symbol: P2rx3
Name: purinergic receptor P2X 3
Description: ENCODES a protein that exhibits ATP binding; extracellularly ATP-gated cation channel activity; INVOLVED IN behavioral response to formalin induced pain; neuronal action potential; positive regulation of sensory perception of pain; PARTICIPATES IN calcium/calcium-mediated signaling pathway; ASSOCIATED WITH Hyperalgesia (ortholog); Trauma, Nervous System (ortholog); FOUND IN dendritic spine; Golgi apparatus; membrane; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ATP receptor; P2X purinoceptor 3; P2X3; purinergic receptor P2X ligand-gated ion channel, 3; purinergic receptor P2X, ligand-gated ion channel, 3
Homo sapiens (human) : P2RX3 (purinergic receptor P2X 3)  HGNC  Alliance
Mus musculus (house mouse) : P2rx3 (purinergic receptor P2X, ligand-gated ion channel, 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : P2rx3 (purinergic receptor P2X 3)
Pan paniscus (bonobo/pygmy chimpanzee) : P2RX3 (purinergic receptor P2X 3)
Canis lupus familiaris (dog) : P2RX3 (purinergic receptor P2X 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : P2rx3 (purinergic receptor P2X 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0372,403,992 - 72,447,801 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0378,914,029 - 78,958,459 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4368,228,045 - 68,270,751 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1368,124,416 - 68,167,123 (-)NCBI
Celera369,431,850 - 69,475,670 (-)NCBICelera
Cytogenetic Map3q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on P2rx3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620253
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2018-02-06
Status: ACTIVE