Slc28a2 (solute carrier family 28 member 2)

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Gene: Slc28a2 (solute carrier family 28 member 2) Rattus norvegicus

Analyze

Symbol:

Slc28a2

Name:

solute carrier family 28 member 2

RGD ID:

61840

Description:

Enables nucleoside:sodium symporter activity. Involved in protein localization to cell surface and retina homeostasis. Located in coated vesicle; plasma membrane; and vesicle membrane. Orthologous to human SLC28A2 (solute carrier family 28 member 2); PARTICIPATES IN azathioprine pharmacodynamics pathway; mercaptopurine pharmacodynamics pathway; mercaptopurine pharmacokinetics pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 17beta-estradiol 3-benzoate.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

CNT 2; concentrative nucleoside transporter 2; LOC102556085; Na(+)/nucleoside cotransporter 2; rCNT2; sodium-coupled nucleoside transporter 2; sodium/nucleoside cotransporter 2; sodium/nucleoside cotransporter 2-like; sodium/purine nucleoside cotransporter; solute carrier family 28 (concentrative nucleoside transporter), member 2; solute carrier family 28 (sodium-coupled nucleoside transporter) member 2; solute carrier family 28 (sodium-coupled nucleoside transporter), member 2; solute carrier family 28, member 2; SPNT

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SLC28A2 (solute carrier family 28 member 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Slc28a2 (solute carrier family 28 (sodium-coupled nucleoside transporter), member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Slc28a2 (solute carrier family 28 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SLC28A2 (solute carrier family 28 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Slc28a2 (solute carrier family 28 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SLC28A2 (solute carrier family 28 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SLC28A2 (solute carrier family 28 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Slc28a2 (solute carrier family 28 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	SLC28A1 (solute carrier family 28 member 1)	HGNC	OrthoDB
Alliance orthologs ³
Mus musculus (house mouse):	Slc28a2 (solute carrier family 28 (sodium-coupled nucleoside transporter), member 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	SLC28A2 (solute carrier family 28 member 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Slc28a2b (solute carrier family 28 member 2b)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	slc28a1 (solute carrier family 28 member 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	slc-28.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CNT1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CNT2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	slc-28.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	109,324,815 - 109,387,702 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	109,366,996 - 109,387,702 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	113,039,238 - 113,060,743 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	3	121,634,754 - 121,656,259 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	3	119,295,132 - 119,316,637 (+)	NCBI	Rnor_WKY
Rnor_6.0	3	114,355,003 - 114,647,382 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	114,355,798 - 114,647,382 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	120,897,082 - 120,921,371 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	109,350,531 - 109,372,027 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	109,256,103 - 109,277,600 (-)	NCBI
Celera	3	108,262,866 - 108,284,103 (+)	NCBI		Celera
Cytogenetic Map	3	q35	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

AGAT deficiency (ISO)

Bloom syndrome (ISO)

colorectal cancer (ISO)

Experimental Diabetes Mellitus (IDA)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (EXP)

17beta-estradiol 3-benzoate (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,4-dinitrotoluene (EXP)

3,3',4,4',5-pentachlorobiphenyl (EXP)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

aconitine (EXP)

acrylamide (EXP)

adenosine (ISO)

aflatoxin B1 (ISO)

ammonium chloride (EXP)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

buspirone (EXP)

buta-1,3-diene (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

clofibrate (EXP)

clofibric acid (EXP)

cobalt dichloride (EXP)

coumarin (EXP)

D-penicillamine (EXP)

decabromodiphenyl ether (EXP)

dexamethasone (EXP)

dimethylarsinic acid (ISO)

endosulfan (EXP)

epoxiconazole (ISO)

flutamide (EXP)

genistein (EXP)

gentamycin (EXP)

indole-3-methanol (EXP)

leflunomide (EXP)

methimazole (EXP)

methylarsonic acid (ISO)

N,N-diethyl-m-toluamide (EXP)

N-nitrosodiethylamine (EXP)

nefazodone (EXP)

nimesulide (EXP)

oxaliplatin (EXP)

ozone (ISO)

paclitaxel (EXP)

paracetamol (EXP,ISO)

paraquat (EXP)

permethrin (EXP)

phenobarbital (EXP)

pirinixic acid (EXP,ISO)

pregnenolone 16alpha-carbonitrile (EXP)

resveratrol (ISO)

rotenone (EXP)

sevoflurane (EXP)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sodium atom (ISO)

sodium dichromate (EXP,ISO)

succimer (ISO)

testosterone (EXP)

tetrachloromethane (EXP)

thioacetamide (EXP)

toluene (EXP)

topotecan (EXP)

tributylstannane (ISO)

trovafloxacin (ISO)

tunicamycin (ISO)

uridine (ISO)

ursodeoxycholic acid (EXP)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adenosine transport (ISO)

inosine transport (ISO)

neurotransmitter transport (ISO)

nucleoside transmembrane transport (IBA,IEA,ISO)

protein localization to cell surface (IDA)

purine nucleobase transmembrane transport (ISO)

purine nucleoside transmembrane transport (ISO)

pyrimidine nucleobase transport (IEA)

pyrimidine-containing compound transmembrane transport (ISO)

retina homeostasis (IBA,IDA)

uridine transport (ISO)

Cellular Component

apicolateral plasma membrane (ISO,ISS)

brush border membrane (ISO)

coated vesicle (IDA)

membrane (IEA)

plasma membrane (IBA,IDA)

vesicle membrane (IDA)

Molecular Function

neurotransmitter transmembrane transporter activity (ISO)

nucleoside transmembrane transporter activity (IBA,IDA,IEA)

nucleoside:sodium symporter activity (IBA,IDA,ISO)

purine nucleobase transmembrane transporter activity (ISO)

purine nucleoside transmembrane transporter activity (IBA,ISO)

pyrimidine- and adenine-specific:sodium symporter activity (ISO)

symporter activity (IBA)

uridine transmembrane transporter activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

azathioprine pharmacodynamics pathway (ISO)

mercaptopurine pharmacodynamics pathway (ISO)

mercaptopurine pharmacokinetics pathway (ISO)

tioguanine pharmacodynamics pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Demonstration of the existence of mRNAs encoding N1/cif and N2/cit sodium/nucleoside cotransporters in rat brain.	Anderson CM, etal., Brain Res Mol Brain Res 1996 Dec;42(2):358-61.
2.	Primary structure and functional expression of a cDNA encoding the bile canalicular, purine-specific Na(+)-nucleoside cotransporter.	Che M, etal., J Biol Chem 1995 Jun 9;270(23):13596-9.
3.	Bile acids alter the subcellular localization of CNT2 (concentrative nucleoside cotransporter) and increase CNT2-related transport activity in liver parenchymal cells.	Fernandez-Veledo S, etal., Biochem J. 2006 Apr 15;395(2):337-44.
4.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
6.	Characterization of the rat Na+/nucleoside cotransporter 2 and transport of nucleoside-derived drugs using electrophysiological methods.	Larrayoz IM, etal., Am J Physiol Cell Physiol. 2006 Dec;291(6):C1395-404. Epub 2006 Jul 12.
7.	Cloned blood-brain barrier adenosine transporter is identical to the rat concentrative Na+ nucleoside cotransporter CNT2.	Li JY, etal., J Cereb Blood Flow Metab 2001 Aug;21(8):929-36.
8.	Ecto-ATPase inhibition: ATP and adenosine release under physiological and ischemic in vivo conditions in the rat striatum.	Melani A, etal., Exp Neurol. 2012 Jan;233(1):193-204. doi: 10.1016/j.expneurol.2011.09.036. Epub 2011 Oct 6.
9.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
10.	Study on intestinal absorption sites of mizoribine and ribavirin, substrates for concentrative nucleoside transporter(s), in rats.	Mori N, etal., Eur J Pharmacol. 2010 Feb 25;628(1-3):214-9. Epub 2009 Dec 2.
11.	Functional and molecular characterization of adenosine transport at the rat inner blood-retinal barrier.	Nagase K, etal., Biochim Biophys Acta. 2006 Jan;1758(1):13-9. Epub 2006 Feb 2.
12.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
13.	SMPDB Annotation Import Pipeline	Pipeline to import SMPDB annotations from SMPDB into RGD
14.	GOA pipeline	RGD automated data pipeline
15.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
17.	Expression of concentrative nucleoside transporters SLC28 (CNT1, CNT2, and CNT3) along the rat nephron: effect of diabetes.	Rodriguez-Mulero S, etal., Kidney Int. 2005 Aug;68(2):665-72.
18.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
19.	Transport of adenosine by recombinant purine- and pyrimidine-selective sodium/nucleoside cotransporters from rat jejunum expressed in Xenopus laevis oocytes.	Yao SY, etal., Mol Pharmacol 1996 Dec;50(6):1529-35.

Additional References at PubMed

PMID:1315767	PMID:10721696	PMID:15024061	PMID:15287894	PMID:16840788	PMID:17013559	PMID:20421393	PMID:22136384	PMID:22354287	PMID:23819782	PMID:25315414	PMID:28322028

Genomics

Comparative Map Data

Slc28a2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	109,324,815 - 109,387,702 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	109,366,996 - 109,387,702 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	113,039,238 - 113,060,743 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	3	121,634,754 - 121,656,259 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	3	119,295,132 - 119,316,637 (+)	NCBI	Rnor_WKY
Rnor_6.0	3	114,355,003 - 114,647,382 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	114,355,798 - 114,647,382 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	120,897,082 - 120,921,371 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	109,350,531 - 109,372,027 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	109,256,103 - 109,277,600 (-)	NCBI
Celera	3	108,262,866 - 108,284,103 (+)	NCBI		Celera
Cytogenetic Map	3	q35	NCBI

SLC28A2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	45,252,234 - 45,277,846 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	15	45,252,234 - 45,277,846 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	45,544,432 - 45,570,044 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	43,331,726 - 43,355,425 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	15	43,331,725 - 43,355,425	NCBI
Celera	15	22,435,715 - 22,459,420 (+)	NCBI		Celera
Cytogenetic Map	15	q21.1	NCBI
HuRef	15	22,368,444 - 22,392,157 (+)	NCBI		HuRef
CHM1_1	15	45,662,894 - 45,686,614 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	15	43,060,158 - 43,086,086 (+)	NCBI		T2T-CHM13v2.0

Slc28a2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	122,256,836 - 122,291,633 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	122,256,958 - 122,291,618 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	122,426,357 - 122,461,152 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	122,426,477 - 122,461,137 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	122,252,213 - 122,286,866 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	122,117,918 - 122,152,571 (+)	NCBI		MGSCv36	mm8
Celera	2	123,576,831 - 123,613,534 (+)	NCBI		Celera
Cytogenetic Map	2	E5	NCBI

Slc28a2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955409	8,144,304 - 8,175,360 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955409	8,145,723 - 8,175,256 (-)	NCBI	ChiLan1.0	ChiLan1.0

SLC28A2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	15	42,554,204 - 42,577,891 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	42,554,142 - 42,578,096 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	15	24,199,846 - 24,223,378 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

Slc28a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	90,088,338 - 90,119,863 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936471	7,937,490 - 7,967,568 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936471	7,937,490 - 7,967,568 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC28A2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	126,472,525 - 126,511,095 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	126,472,500 - 126,511,207 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	141,072,725 - 141,110,169 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC28A2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	37,927,200 - 37,956,729 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666048	103,107,096 - 103,134,707 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc28a2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624731	13,998,505 - 14,025,732 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624731	13,999,029 - 14,051,964 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Slc28a2
1324 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	96
Count of miRNA genes:	87
Interacting mature miRNAs:	91
Transcripts:	ENSRNOT00000036435
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	29463235	118376539	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	31172320	163586636	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	38192233	133483320	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	41874578	155617519	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	41874578	155617519	Rat
1581503	Cm58	Cardiac mass QTL 58	2.7	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	43827364	121056321	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	43827364	169034231	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	47233211	147415807	Rat
1358186	Ept2	Estrogen-induced pituitary tumorigenesis QTL 2	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	47233430	110362260	Rat
2292613	Ept16	Estrogen-induced pituitary tumorigenesis QTL 16	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	47233430	110362260	Rat
631665	Bw8	Body weight QTL 8	5.5		body mass (VT:0001259)	body weight (CMO:0000012)	3	50437042	119183768	Rat
724523	Tsu1	Thymus enlargement suppressive QTL 1	3.84		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	3	50437504	115638231	Rat
1582218	Bw74	Body weight QTL 74	3.9	0.0021	body mass (VT:0001259)	body weight (CMO:0000012)	3	53184593	115665732	Rat
1582238	Bw68	Body weight QTL 68	3.2	0.0064	body mass (VT:0001259)	body weight (CMO:0000012)	3	53184593	115665732	Rat
1582239	Epfw1	Epididymal fat weight QTL 1	4.5	0.0006	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	3	53184593	115665732	Rat
1581568	Rf53	Renal function QTL 53			urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	3	56395968	161299569	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	59242096	157323038	Rat
1300111	Rf12	Renal function QTL 12	3.78		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	61017749	121056321	Rat
1582210	Bw71	Body weight QTL 71	3.3	0.0012	body mass (VT:0001259)	body weight (CMO:0000012)	3	64655305	115665732	Rat
1582221	Kidm30	Kidney mass QTL 30	3.5	0.0008	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	3	64655305	115665732	Rat
12879848	Bw181	Body weght QTL 181		0.015	body mass (VT:0001259)	body weight (CMO:0000012)	3	70348525	121056321	Rat
2301414	Kidm37	Kidney mass QTL 37		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	70653097	121056321	Rat
1600376	Arunc5	Aerobic running capacity QTL 5		0.21	exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	3	73376539	118376539	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	78196190	146592722	Rat
2302273	Gluco35	Glucose level QTL 35	5.3	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	80800231	114297550	Rat
631649	Bp123	Blood pressure QTL 123	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	89772419	134772419	Rat
8694437	Bw167	Body weight QTL 167	22.46	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	3	91797474	136797474	Rat
631841	Niddm39	Non-insulin dependent diabetes mellitus QTL 39	3.36		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	94856903	159898684	Rat
724532	Cm17	Cardiac mass QTL 17	2		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	3	95735366	140735366	Rat
1582219	Bw63	Body weight QTL 63	3.8	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	3	96127817	115665732	Rat
1354611	Despr2	Despair related QTL 2	3.03	0.0028	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	3	97084464	142084464	Rat
2293087	Iddm27	Insulin dependent diabetes mellitus QTL 27	2.68		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	97551417	147415807	Rat
2312659	Slep7	Serum leptin concentration QTL 7		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	3	98535255	168026850	Rat
2312670	Bw94	Body weight QTL 94		0.01	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	3	98535255	168026850	Rat
2312673	Scl63	Serum cholesterol level QTL 63		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	98535255	168026850	Rat
2302373	Gluco39	Glucose level QTL 39	5.01		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	3	98535386	161695835	Rat
1582216	Bw65	Body weight QTL 65	6.3		body mass (VT:0001259)	body weight (CMO:0000012)	3	102200529	115665732	Rat
619618	Rf3	Renal disease susceptibility QTL 3	6.5	0.001	urine albumin amount (VT:0002871)	urine albumin excretion rate to body weight ratio (CMO:0001270)	3	107693393	152693393	Rat

Markers in Region

RH127610

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	109,534,736 - 109,534,918 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	114,379,146 - 114,379,328	NCBI	Rnor6.0
Rnor_5.0	3	120,920,944 - 120,921,126	UniSTS	Rnor5.0
RGSC_v3.4	3	109,199,517 - 109,199,698	UniSTS	RGSC3.4
RH 3.4 Map	3	954.4	UniSTS
Cytogenetic Map	3	q35	UniSTS

RH131217

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	109,387,372 - 109,387,564 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	114,647,053 - 114,647,244	NCBI	Rnor6.0
Rnor_5.0	3	121,185,952 - 121,186,143	UniSTS	Rnor5.0
RGSC_v3.4	3	109,350,669 - 109,350,860	UniSTS	RGSC3.4
Celera	3	108,476,193 - 108,476,389	UniSTS
Celera	3	108,283,774 - 108,283,965	UniSTS
RH 3.4 Map	3	953.5	UniSTS
Cytogenetic Map	3	q35	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	2	10	25	15	18	15			27		3	4
Low	1	33	32	26	1	26	8	11	47	35	36	7	8
Below cutoff											2

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_031664	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105767	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105768	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105769	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105770	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005501974	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB485922	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY029302	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EU032627	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000118	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U25055	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U66723	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U67084	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000024658 ⟹ ENSRNOP00000024658

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	109,366,996 - 109,387,702 (+)	Ensembl
Rnor_6.0 Ensembl	3	114,355,798 - 114,647,382 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000036435 ⟹ ENSRNOP00000034564

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	3	114,355,814 - 114,378,941 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000083380

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	3	114,650,518 - 114,652,214 (+)	Ensembl

RefSeq Acc Id:

NM_031664 ⟹ NP_113852

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	109,366,196 - 109,387,702 (+)	NCBI
Rnor_6.0	3	114,355,003 - 114,647,382 (+)	NCBI
Rnor_5.0	3	120,897,082 - 120,921,371 (+)	NCBI
RGSC_v3.4	3	109,350,531 - 109,372,027 (-)	RGD
Celera	3	108,262,866 - 108,284,103 (+)	RGD

Sequence:

show sequence

CCACGCGTCCGGTCTTGCTGAAGGGAAACCTCCACTTCCTGCTTGTGAGAGTATTAATCCCTGC
TGCAGCTGTCCATCCCCACTGACATCAGACTCCAGTTTCTCCAGGATCCAGTGTGTTCTGAAGA
TCAGCAGCTCTCCCGGAGTCTTCAAGGCGCCAGATTTGGAAGTCTGAGGCATCTGGCTTTGTAA
CCTGAGCAGCTGCCAGGTTCCAGCCATTATCTGACTGGGCTGTGCGGACCCACCCAGCACATTC
AGAGGATAACAGGAGATGGCGAAGTCAGAGGGAAGAAAGTCTGCTTCCCAGGACACATCGGAGA
ATGGCATGGAGAACCCAGGCCTGGAGCTCATGGAAGTCGGAAACCTTGAGCAAGGCAAAACACT
GGAGGAAGTGACACAGGGACATAGCCTGAAGGATGGCTTGGGGCATTCCTCTCTCTGGAGGAGG
ATTCTTCAGCCCTTCACCAAGGCGAGAAGTTTCTATCAAAGACATGCTGGTTTATTCAAAAAGA
TCCTGCTTGGTCTCTTGTGTTTAGCGTATGCTGCCTACCTCCTGGCAGCTTGCATCCTGAACTT
CCGGAGGGCACTGGCCTTGTTTGTCATCACCTGCCTTGTCATCTTCATCCTGGCTTGCCACTTT
CTGAAAAAATTCTTTGCTAAAAAGTCAATAAGATGCTTGAAGCCCTTGAAAAACACCCGCCTGA
GACTTTGGCTTAAGAGGGTGTTCATGGGAGCCGCTGTTGTCGGCCTTATTCTCTGGCTGGCTCT
GGACACAGCTCAAAGGCCAGAGCAGCTGATCTCCTTTGCGGGAATCTGCATGTTCATCCTCATC
CTCTTTGCCTGCTCCAAACACCACAGTGCGGTGAGCTGGAGGACAGTGTTTTGGGGCCTGGGCC
TTCAGTTCGTCTTTGGGATTTTGGTCATCAGAACTGAACCTGGATTTAATGCATTTCAATGGCT
GGGAGATCAGATCCAGATTTTCCTGGCATATACTGTAGAAGGATCCAGTTTTGTTTTTGGTGAC
ACACTGGTCCAAAGTGTTTTTGCTTTTCAGTCTCTCCCAATCATTATTTTCTTCGGATGTGTGA
TGTCTATTCTCTACTACCTGGGCCTTGTGCAGTGGGTGATCCAGAAGATTGCCTGGTTCCTGCA
AATCACCATGGGTACCACAGCTGCAGAGACCCTGGCCGTGGCAGGAAACATCTTTGTGGGAATG
ACAGAGGCACCTCTGCTCATCCGTCCCTACCTTGCAGACATGACCCTCTCTGAAATCCATGCAG
TGATGACTGGAGGCTTTGCTACTATAGCAGGCACAGTGTTGGGAGCCTTCATATCCTTTGGGAT
TGATGCATCATCCTTGATTTCTGCCTCAGTGATGGCTGCCCCTTGTGCACTTGCCTTGTCCAAA
CTGGTATATCCAGAAGTAGAAGAGTCCAAGTTCAAGAGCAAGGAGGGAGTGAAGCTGCCTCGAG
GGGAAGAGAGGAATATTCTGGAAGCCGCGAGCAACGGAGCCACAGATGCCATAGCGCTTGTTGC
TAATGTTGCAGCCAACCTGATTGCCTTTCTGGCTGTATTGGCCTTCATCAATTCTACCCTTTCC
TGGCTGGGGGAAATGGTGGATATCCATGGACTCACTTTCCAGGTCATCTGCTCCTATGTCCTAA
GGCCAATGGTTTTCATGATGGGTGTACAGTGGGCAGACTGCCCATTGGTGGCTGAGATAGTGGG
AGTCAAATTCTTCATAAATGAATTTGTGGCCTATCAACAACTGTCTCAGTACAAGAACAAACGT
CTCTCTGGAGTCGAAGAGTGGATCAATGGCGAGAAACAGTGGATTTCTGTGAAGGCTGAAATCA
TTGCAACATTTTCTCTCTGTGGATTTGCCAATCTTACTTCCATAGGGATCACACTGGGAGGCTT
GACATCCATGGTTCCCCAACGGAAGAGTGACTTGTGCAAGCTTGTGGTCAGGGCCCTCTTCACA
GGTGCCTGTGTTTCCTTCATCAGTGCCTGTATGGCAGGAATCCTCTATGTTCCCAGAGGCGCTG
AAACTGACTGTGTCTCATTCTTAAACACAAATTTCACCAACAGAACCTATGAGACATATGTGTG
CTGCAGAGAGCTCTTCCAGAGTACTTTGCTGAATGGCACCAACATGCCTTCTTTCTCAGGCCCC
TGGCAAGACAAGGAGTCCAGCCTCAGGAATCTTGCTAAATGCTGTGACCTCTATACCAGCACTG
TGTGTGCCTGAGGCTGGTGGGGCCATTCCGTGACAGTTCTTATAGAACAGATTCATATTACCAA
ATACATGTTCATGTACTTAGGCTTATTCTCTGAGAACTGCACTAAACTCCACAAAATGAAAGTC
CTGATCTCACTGTGGCTCTGTATAAAAACCAGCATCCACCTTTCCACTGGCATGCCACATAGTA
GATGTGAAATTCATTATAGACCCTCTTGAGCCAAAGTATGGTGGGAATGTAGCTAAGGGGGAAA
TATGTGTGTGGTAAGTGCTAAGATGGAGATTCAACCCCTGGCCAGGGCCAGAGTGGGGAGAGTG
GGGAAATCCAAGTAGATGCTTAGATTTAACTTGGTGGTACACCCTGTGGTCACTTACCTGTAAG
CTCAGAGCTAAGGGGATTGCCTCAGATCCAAGGCAAGCCTGGCCCGAACCCTGAAGTCTTTCAC
AGAAGTGATAGAGTAGAGGCCATGTCCTTGGGCAGGGATGGAGGTGAGGGAATATATTTCTAAA
GTTATATGGGAAACACTTGTGAATACTTAATGATAACATATTTTTTATTGCCAAAGGTTGTATA
CTTAAAAACTCTTTTCATTTTCATACATTACTAAAAAGCTTTCTGTAATAAAGTGTTTTTATGT
A

hide sequence

RefSeq Acc Id:

XM_039105767 ⟹ XP_038961695

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	109,324,815 - 109,387,699 (+)	NCBI

RefSeq Acc Id:

XM_039105768 ⟹ XP_038961696

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	109,363,227 - 109,387,185 (+)	NCBI

RefSeq Acc Id:

XM_039105769 ⟹ XP_038961697

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	109,324,815 - 109,387,699 (+)	NCBI

RefSeq Acc Id:

XM_039105770 ⟹ XP_038961698

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	109,366,528 - 109,387,185 (+)	NCBI

RefSeq Acc Id:

XR_005501974

RefSeq Status:

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	109,363,227 - 109,385,722 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_113852	(Get FASTA)	NCBI Sequence Viewer
	XP_038961695	(Get FASTA)	NCBI Sequence Viewer
	XP_038961696	(Get FASTA)	NCBI Sequence Viewer
	XP_038961697	(Get FASTA)	NCBI Sequence Viewer
	XP_038961698	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA80640	(Get FASTA)	NCBI Sequence Viewer
	AAD00159	(Get FASTA)	NCBI Sequence Viewer
	AAD00160	(Get FASTA)	NCBI Sequence Viewer
	AAK38150	(Get FASTA)	NCBI Sequence Viewer
	BAH58083	(Get FASTA)	NCBI Sequence Viewer
	Q62773	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_113852 ⟸ NM_031664

- UniProtKB:

F1LN73 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAKSEGRKSASQDTSENGMENPGLELMEVGNLEQGKTLEEVTQGHSLKDGLGHSSLWRRILQPF
TKARSFYQRHAGLFKKILLGLLCLAYAAYLLAACILNFRRALALFVITCLVIFILACHFLKKFF
AKKSIRCLKPLKNTRLRLWLKRVFMGAAVVGLILWLALDTAQRPEQLISFAGICMFILILFACS
KHHSAVSWRTVFWGLGLQFVFGILVIRTEPGFNAFQWLGDQIQIFLAYTVEGSSFVFGDTLVQS
VFAFQSLPIIIFFGCVMSILYYLGLVQWVIQKIAWFLQITMGTTAAETLAVAGNIFVGMTEAPL
LIRPYLADMTLSEIHAVMTGGFATIAGTVLGAFISFGIDASSLISASVMAAPCALALSKLVYPE
VEESKFKSKEGVKLPRGEERNILEAASNGATDAIALVANVAANLIAFLAVLAFINSTLSWLGEM
VDIHGLTFQVICSYVLRPMVFMMGVQWADCPLVAEIVGVKFFINEFVAYQQLSQYKNKRLSGVE
EWINGEKQWISVKAEIIATFSLCGFANLTSIGITLGGLTSMVPQRKSDLCKLVVRALFTGACVS
FISACMAGILYVPRGAETDCVSFLNTNFTNRTYETYVCCRELFQSTLLNGTNMPSFSGPWQDKE
SSLRNLAKCCDLYTSTVCA

hide sequence

RefSeq Acc Id:

ENSRNOP00000024658 ⟸ ENSRNOT00000024658

RefSeq Acc Id:

ENSRNOP00000034564 ⟸ ENSRNOT00000036435

RefSeq Acc Id:	XP_038961695 ⟸ XM_039105767
- Peptide Label:	isoform X1
- UniProtKB:	F1LN73 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038961697 ⟸ XM_039105769
- Peptide Label:	isoform X1
- UniProtKB:	F1LN73 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038961696 ⟸ XM_039105768
- Peptide Label:	isoform X1
- UniProtKB:	F1LN73 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038961698 ⟸ XM_039105770
- Peptide Label:	isoform X1
- UniProtKB:	F1LN73 (UniProtKB/TrEMBL)

Protein Domains

Gate Nucleos_tra2_C Nucleos_tra2_N

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q62773-F1-model_v2	AlphaFold	Q62773	1-659	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692368

Promoter ID:

EPDNEW_R2893

Type:

single initiation site

Name:

Slc28a2_1

Description:

solute carrier family 28 member 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	114,355,796 - 114,355,856	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:61840	AgrOrtholog
BioCyc Gene	G2FUF-48096	BioCyc
Ensembl Genes	ENSRNOG00000028668	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOG00000052651	Ensembl
Ensembl Protein	ENSRNOP00000024658	ENTREZGENE
	ENSRNOP00000024658.7	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000024658	ENTREZGENE
	ENSRNOT00000024658.8	UniProtKB/TrEMBL
InterPro	C_nuclsd_transpt	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	C_nuclsd_transpt_met_bac	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CNT1/CNT2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CNT_C_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CNT_N_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Gate_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:60423	UniProtKB/Swiss-Prot
NCBI Gene	60423	ENTREZGENE
PANTHER	PTHR10590	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR10590:SF11	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Gate	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Nucleos_tra2_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Nucleos_tra2_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB	SLC28A2	RGD
PhenoGen	Slc28a2	PhenoGen
TIGR	TC230283
TIGRFAMs	nupC	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	C1PHX8_RAT	UniProtKB/TrEMBL
	F1LN73	ENTREZGENE, UniProtKB/TrEMBL
	Q62773	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	Q9QWI3	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Slc28a2	solute carrier family 28 member 2	LOC102556085	sodium/nucleoside cotransporter 2-like	Data Merged	737654	PROVISIONAL
2016-02-24	Slc28a2	solute carrier family 28 member 2	Slc28a2	solute carrier family 28 (concentrative nucleoside transporter), member 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2014-07-25	Slc28a2	solute carrier family 28 (concentrative nucleoside transporter), member 2	Slc28a2	solute carrier family 28 (sodium-coupled nucleoside transporter), member 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-12-17	LOC102556085	sodium/nucleoside cotransporter 2-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2004-09-10	Slc28a2	solute carrier family 28 (sodium-coupled nucleoside transporter), member 2		solute carrier family 28, member 2	Name updated	1299863	APPROVED
2002-06-10	Slc28a2	solute carrier family 28, member 2			Name updated	70584	APPROVED

RGD Curation Notes

Note Type	Note	Reference

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Annotations - SMPDB