Or5g25 (olfactory receptor family 5 subfamily G member 25) - Rat Genome Database

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Gene: Or5g25 (olfactory receptor family 5 subfamily G member 25) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or5g25
Name: olfactory receptor family 5 subfamily G member 25
RGD ID: 1333343
Description: Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 448; olfactory receptor gene Olr448; olfactory receptor Olr448; Olr448
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8391,125,421 - 91,128,774 (-)NCBIGRCr8
mRatBN7.2370,718,741 - 70,719,697 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl370,718,741 - 70,719,697 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx374,117,523 - 74,118,479 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0382,716,204 - 82,717,160 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0380,488,347 - 80,489,303 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0373,039,093 - 73,040,049 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl373,039,093 - 73,040,049 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0379,607,286 - 79,608,242 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4368,882,364 - 68,883,320 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1368,778,735 - 68,779,692 (-)NCBI
Celera370,055,835 - 70,056,791 (-)NCBICelera
Cytogenetic Map3q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or5g25Ratdetection of chemical stimulus involved in sensory perception of smell involved_inIEAGO:00049841600115GO_REF:0000108GOCGO_REF:0000108
Or5g25Ratdetection of chemical stimulus involved in sensory perception of smell  IEA (All species)1303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 
Or5g25RatG protein-coupled receptor signaling pathway involved_inIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043
Or5g25RatG protein-coupled receptor signaling pathway  IEA (All species)1303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 
Or5g25RatG protein-coupled receptor signaling pathway involved_inIEAInterPro:IPR000276 and InterPro:IPR0007251600115GO_REF:0000002InterProGO_REF:0000002
Or5g25Ratsensory perception of smell involved_inIEAUniProtKB-KW:KW-05521600115GO_REF:0000043UniProtGO_REF:0000043
Or5g25Ratsignal transduction involved_inIEAUniProtKB-KW:KW-08071600115GO_REF:0000043UniProtGO_REF:0000043

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or5g25Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Or5g25Ratmembrane located_inIEAInterPro:IPR000276 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Or5g25Ratplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044
Or5g25Ratplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or5g25RatG protein-coupled receptor activity enablesIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043
Or5g25RatG protein-coupled receptor activity enablesIEAInterPro:IPR0002761600115GO_REF:0000002InterProGO_REF:0000002
Or5g25Ratodorant binding enablesIBAMGI:3030853 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Or5g25Ratolfactory receptor activity enablesIBAMGI:3030069 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Or5g25Ratolfactory receptor activity  IEA (All species)1303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 
Or5g25Ratolfactory receptor activity enablesIEAInterPro:IPR0007251600115GO_REF:0000002InterProGO_REF:0000002

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or5g25Rattaste/olfaction phenotype  IEA 1303377 RGD 

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline


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Variants in Or5g25
2 total Variants

Predicted Target Of
Summary Value
Count of predictions:106
Count of miRNA genes:91
Interacting mature miRNAs:97
Transcripts:ENSRNOT00000012629
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 48 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)34382736490905114Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)35318469289878207Rat
2302055Pia30Pristane induced arthritis QTL 303.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)32793691972936919Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)33945463789115240Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)33370334778196190Rat
2303593Gluco46Glucose level QTL 463blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)32846857173468571Rat

1 to 10 of 48 rows



endocrine system
endoderm
exocrine system
hepatobiliary system
mesenchyme
reproductive system
1 1 1 1 1 7



Ensembl Acc Id: ENSRNOT00000012629   ⟹   ENSRNOP00000012629
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl370,718,741 - 70,719,697 (-)Ensembl
Rnor_6.0 Ensembl373,039,093 - 73,040,049 (-)Ensembl
RefSeq Acc Id: NM_001000287   ⟹   NP_001000287
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8391,125,421 - 91,126,377 (-)NCBI
mRatBN7.2370,718,741 - 70,719,697 (-)NCBI
Rnor_6.0373,039,093 - 73,040,049 (-)NCBI
Rnor_5.0379,607,286 - 79,608,242 (-)NCBI
RGSC_v3.4368,882,364 - 68,883,320 (-)RGD
Celera370,055,835 - 70,056,791 (-)RGD
Sequence:
RefSeq Acc Id: XM_063283284   ⟹   XP_063139354
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8391,125,421 - 91,128,774 (-)NCBI
Protein RefSeqs NP_001000287 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139354 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000012629
  ENSRNOP00000012629.1
RefSeq Acc Id: NP_001000287   ⟸   NM_001000287
- UniProtKB: D3ZGL9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000012629   ⟸   ENSRNOT00000012629
RefSeq Acc Id: XP_063139354   ⟸   XM_063283284
- Peptide Label: isoform X1
- UniProtKB: D3ZGL9 (UniProtKB/TrEMBL)
G-protein coupled receptors family 1 profile

Name Modeler Protein Id AA Range Protein Structure
AF-D3ZGL9-F1-model_v2 AlphaFold D3ZGL9 1-318 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 20 of 20 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-49116 BioCyc
Ensembl Genes ENSRNOG00000009526 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000012629 ENTREZGENE
  ENSRNOT00000012629.3 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:295720 UniProtKB/TrEMBL
NCBI Gene 295720 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or5g25 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009526 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt D3ZGL9 ENTREZGENE, UniProtKB/TrEMBL
1 to 20 of 20 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or5g25  olfactory receptor family 5 subfamily G member 25  Olr448  olfactory receptor 448  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr448  olfactory receptor 448   Olr448_predicted  olfactory receptor 448 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr448_predicted  olfactory receptor 448 (predicted)      Symbol and Name status set to approved 70820 APPROVED