Hnrnpa3 (heterogeneous nuclear ribonucleoprotein A3) - Rat Genome Database

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Gene: Hnrnpa3 (heterogeneous nuclear ribonucleoprotein A3) Rattus norvegicus
Analyze
Symbol: Hnrnpa3
Name: heterogeneous nuclear ribonucleoprotein A3
RGD ID: 727807
Description: Enables RNA transmembrane transporter activity and mRNA binding activity. Involved in mRNA transport. Located in ribonucleoprotein granule. Part of ribonucleoprotein complex. Is active in glutamatergic synapse and postsynaptic density. Biomarker of silicosis. Orthologous to human HNRNPA3 (heterogeneous nuclear ribonucleoprotein A3); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hnRNP A3; Hnrpa3; mBx
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8380,984,470 - 80,999,413 (+)NCBIGRCr8
mRatBN7.2360,578,574 - 60,588,755 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl360,578,673 - 60,588,306 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx363,952,911 - 63,963,020 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0372,536,567 - 72,546,676 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0370,302,815 - 70,312,930 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0362,481,222 - 62,491,356 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl362,481,323 - 62,487,227 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0369,029,029 - 69,036,149 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4368,872,863 - 68,875,337 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera360,079,220 - 60,089,344 (+)NCBICelera
Cytogenetic Map3q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
(Z)-3-butylidenephthalide  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2,4-dinitrotoluene  (EXP)
2,6-dimethoxyphenol  (ISO)
2,6-dinitrotoluene  (EXP)
3',5'-cyclic UMP  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acrylamide  (EXP)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bleomycin A2  (EXP)
butan-1-ol  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
cantharidin  (ISO)
carbon nanotube  (ISO)
carnosic acid  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
cytarabine  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (EXP,ISO)
Dibutyl phosphate  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
diuron  (EXP)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
eugenol  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
fructose  (EXP)
furfural  (ISO)
gentamycin  (EXP)
inulin  (ISO)
irinotecan  (ISO)
isobutanol  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
methapyrilene  (EXP)
methyl methanesulfonate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
nickel subsulfide  (EXP)
nicotine  (ISO)
Nutlin-3  (ISO)
oxaliplatin  (EXP)
ozone  (EXP)
paracetamol  (ISO)
PCB138  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (EXP)
piroxicam  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
succimer  (ISO)
T-2 toxin  (EXP)
tamoxifen  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone undecanoate  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
triptonide  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. [Differential analysis of two-dimensional gel electrophoresis profiles in lung tissue of rats exposed to silica early]. Chen JJ, etal., Zhonghua Yu Fang Yi Xue Za Zhi. 2009 May;43(5):418-22.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Identification and verification of novel rodent postsynaptic density proteins. Jordan BA, etal., Mol Cell Proteomics. 2004 Sep;3(9):857-71. doi: 10.1074/mcp.M400045-MCP200. Epub 2004 May 28.
4. Heterogeneous nuclear ribonucleoprotein A3, a novel RNA trafficking response element-binding protein. Ma AS, etal., J Biol Chem 2002 May 17;277(20):18010-20.
5. NCBI rat LocusLink and RefSeq merged data October 15, 2003 NCBI rat LocusLink and RefSeq merged data October 15, 2003
6. Nuclear actin is associated with a specific subset of hnRNP A/B-type proteins. Percipalle P, etal., Nucleic Acids Res. 2002 Apr 15;30(8):1725-34.
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. Molecular characterization of a murine, major A/B type hnRNP protein: mBx. Plomaritoglou A, etal., Biochim Biophys Acta 2000 Jan 31;1490(1-2):54-62.
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:8889548   PMID:11991638   PMID:12947022   PMID:14766980   PMID:15489334   PMID:16641100   PMID:16854843   PMID:22658674   PMID:22681889   PMID:22720776   PMID:24625528   PMID:26316108  
PMID:27461252   PMID:29476059   PMID:32357304   PMID:35352799  


Genomics

Comparative Map Data
Hnrnpa3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8380,984,470 - 80,999,413 (+)NCBIGRCr8
mRatBN7.2360,578,574 - 60,588,755 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl360,578,673 - 60,588,306 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx363,952,911 - 63,963,020 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0372,536,567 - 72,546,676 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0370,302,815 - 70,312,930 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0362,481,222 - 62,491,356 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl362,481,323 - 62,487,227 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0369,029,029 - 69,036,149 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4368,872,863 - 68,875,337 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera360,079,220 - 60,089,344 (+)NCBICelera
Cytogenetic Map3q23NCBI
HNRNPA3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382177,212,794 - 177,223,959 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2177,212,694 - 177,226,106 (+)EnsemblGRCh38hg38GRCh38
GRCh372178,077,522 - 178,088,687 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362177,785,668 - 177,796,931 (+)NCBINCBI36Build 36hg18NCBI36
Build 342177,903,034 - 177,909,534NCBI
Celera2171,679,860 - 171,691,117 (+)NCBICelera
Cytogenetic Map2q31.2NCBI
HuRef2169,948,728 - 169,959,989 (+)NCBIHuRef
CHM1_12178,083,270 - 178,094,521 (+)NCBICHM1_1
T2T-CHM13v2.02177,695,036 - 177,706,189 (+)NCBIT2T-CHM13v2.0
Hnrnpa3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39275,489,416 - 75,499,751 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl275,489,605 - 75,499,751 (+)EnsemblGRCm39 Ensembl
GRCm38275,659,105 - 75,669,407 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl275,659,261 - 75,669,407 (+)EnsemblGRCm38mm10GRCm38
MGSCv37275,497,316 - 75,507,464 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36275,460,116 - 75,470,246 (+)NCBIMGSCv36mm8
Celera277,320,414 - 77,330,443 (+)NCBICelera
Cytogenetic Map2C3NCBI
cM Map244.75NCBI
Hnrnpa3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540319,544,842 - 19,548,417 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540319,540,814 - 19,548,417 (-)NCBIChiLan1.0ChiLan1.0
HNRNPA3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21379,879,341 - 79,890,582 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B79,894,297 - 79,905,555 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B64,491,827 - 64,503,095 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B182,196,645 - 182,208,039 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B182,196,645 - 182,207,937 (+)Ensemblpanpan1.1panPan2
HNRNPA3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13620,974,541 - 20,983,972 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3620,974,648 - 20,980,137 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3620,994,264 - 21,003,455 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03621,118,619 - 21,127,814 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3621,118,687 - 21,128,350 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13621,189,273 - 21,198,469 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03621,190,448 - 21,199,631 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03621,306,219 - 21,315,411 (+)NCBIUU_Cfam_GSD_1.0
Hnrnpa3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303138,022,961 - 138,032,537 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365096,577,001 - 6,581,934 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365096,576,933 - 6,585,734 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HNRNPA3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1582,958,362 - 82,968,736 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11582,958,329 - 82,968,740 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21592,417,689 - 92,428,369 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HNRNPA3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11062,772,741 - 62,780,695 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1062,772,806 - 62,778,972 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040136,826,743 - 136,837,738 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hnrnpa3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478714,341,250 - 14,346,316 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478714,341,133 - 14,352,152 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hnrnpa3
51 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:62
Count of miRNA genes:56
Interacting mature miRNAs:57
Transcripts:ENSRNOT00000035567
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31500542276927699Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
9590286Uminl1Urine mineral level QTL 13.50.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)32824968773249687Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35378111291609953Rat
61356Bp37Blood pressure QTL 373blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)33068464275684642Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
8694196Abfw2Abdominal fat weight QTL 216.580.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)32824968773249687Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
1582249Bw77Body weight QTL 773.20.0025epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)35318459364655484Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
12879868Am6Aortic mass QTL 60.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)33142640370668733Rat
11565451Bw177Body weight QTL 1770.002body mass (VT:0001259)body weight (CMO:0000012)33142640370668733Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
11565452Kidm57Kidney mass QTL 570.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)33142640370668733Rat
12879866Cm94Cardiac mass QTL 940.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)33142640370668733Rat
12879867Cm95Cardiac mass QTL 950.047heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)33142640370668733Rat
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)34382736490905114Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)35318469289878207Rat
2302055Pia30Pristane induced arthritis QTL 303.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)32793691972936919Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)33945463789115240Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)33370334778196190Rat
2303593Gluco46Glucose level QTL 463blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)32846857173468571Rat
1354590Despr11Despair related QTL 110.000031locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)32846857173468571Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)33945463789115240Rat
631647Bp122Blood pressure QTL 1226.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)33068464275684642Rat
1300169Bp177Blood pressure QTL 1772.96arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)33370334761017857Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2302276Bw82Body weight QTL 824.32body mass (VT:0001259)body weight (CMO:0000012)33945463762951183Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)33851780383517803Rat
9590136Scort3Serum corticosterone level QTL 323.370.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)32824968773249687Rat
10450804Scl70Serum cholesterol level QTL 704.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)33035677398535386Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)341874578104104347Rat
8552950Pigfal12Plasma insulin-like growth factor 1 level QTL 127.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)32824968773249687Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)31695470861954708Rat
10450794Scl69Serum cholesterol level QTL 696.30.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
8694386Bw159Body weight QTL 1594.520.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)32824968773249687Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
2301400Cm68Cardiac mass QTL 680.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)33142640370668733Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat

Markers in Region
RH127548  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8380,995,217 - 80,995,434 (+)Marker Load Pipeline
mRatBN7.2360,587,927 - 60,588,144 (+)MAPPERmRatBN7.2
Rnor_6.0362,490,529 - 62,490,745NCBIRnor6.0
Rnor_5.0369,035,322 - 69,035,538UniSTSRnor5.0
RGSC_v3.4358,360,103 - 58,360,319UniSTSRGSC3.4
Celera360,088,517 - 60,088,733UniSTS
Cytogenetic Map3q23UniSTS
RH139237  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2360,588,540 - 60,588,676 (+)MAPPERmRatBN7.2
Rnor_6.0362,491,142 - 62,491,277NCBIRnor6.0
Rnor_5.0369,035,935 - 69,036,070UniSTSRnor5.0
RGSC_v3.4358,360,716 - 58,360,851UniSTSRGSC3.4
Celera360,089,130 - 60,089,265UniSTS
Cytogenetic Map3q23UniSTS
RH136328  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2360,586,292 - 60,586,477 (+)MAPPERmRatBN7.2
Rnor_6.0362,488,894 - 62,489,078NCBIRnor6.0
Rnor_5.0369,033,687 - 69,033,871UniSTSRnor5.0
RGSC_v3.4358,358,468 - 58,358,652UniSTSRGSC3.4
Celera360,086,882 - 60,087,066UniSTS
Cytogenetic Map3q23UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001111294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001111295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_198132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063284131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063284132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063284134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC109877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AT006305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW534817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY363226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC081878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI292197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP488086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB585714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB725005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF110612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF110891 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CV107265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CV109437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220486 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y16641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000078872   ⟹   ENSRNOP00000069876
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl360,578,721 - 60,588,306 (+)Ensembl
Rnor_6.0 Ensembl362,481,323 - 62,487,227 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097068   ⟹   ENSRNOP00000079420
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl360,578,673 - 60,586,630 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000100893   ⟹   ENSRNOP00000079754
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl360,579,298 - 60,586,630 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114122   ⟹   ENSRNOP00000084090
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl360,578,721 - 60,588,306 (+)Ensembl
RefSeq Acc Id: NM_001111294   ⟹   NP_001104764
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8380,985,934 - 80,996,045 (+)NCBI
mRatBN7.2360,578,644 - 60,588,755 (+)NCBI
Rnor_6.0362,481,243 - 62,491,356 (+)NCBI
Rnor_5.0369,029,029 - 69,036,149 (+)NCBI
RGSC_v3.4368,872,863 - 68,875,337 (-)RGD
Celera360,079,220 - 60,089,344 (+)RGD
Sequence:
RefSeq Acc Id: NM_001111295   ⟹   NP_001104765
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8380,985,934 - 80,991,916 (+)NCBI
mRatBN7.2360,578,644 - 60,584,626 (+)NCBI
Rnor_6.0362,481,243 - 62,487,227 (+)NCBI
Rnor_5.0369,029,029 - 69,036,149 (+)NCBI
RGSC_v3.4368,872,863 - 68,875,337 (-)RGD
Celera360,079,220 - 60,085,215 (+)NCBI
Sequence:
RefSeq Acc Id: NM_198132   ⟹   NP_937765
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8380,985,934 - 80,996,045 (+)NCBI
mRatBN7.2360,578,644 - 60,588,755 (+)NCBI
Rnor_6.0362,481,243 - 62,491,356 (+)NCBI
Rnor_5.0369,029,029 - 69,036,149 (+)NCBI
RGSC_v3.4368,872,863 - 68,875,337 (-)RGD
Celera360,079,220 - 60,089,344 (+)RGD
Sequence:
RefSeq Acc Id: XM_008761911   ⟹   XP_008760133
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8380,984,470 - 80,996,045 (+)NCBI
mRatBN7.2360,578,574 - 60,586,630 (+)NCBI
Rnor_6.0362,481,222 - 62,491,352 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008761912   ⟹   XP_008760134
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8380,984,470 - 80,996,045 (+)NCBI
mRatBN7.2360,578,574 - 60,588,755 (+)NCBI
Rnor_6.0362,481,222 - 62,491,356 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063284131   ⟹   XP_063140201
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8380,984,470 - 80,999,413 (+)NCBI
RefSeq Acc Id: XM_063284132   ⟹   XP_063140202
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8380,984,470 - 80,996,045 (+)NCBI
RefSeq Acc Id: XM_063284134   ⟹   XP_063140204
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8380,984,470 - 80,999,413 (+)NCBI
RefSeq Acc Id: NP_937765   ⟸   NM_198132
- Peptide Label: isoform a
- UniProtKB: Q6URK3 (UniProtKB/Swiss-Prot),   Q6URK4 (UniProtKB/Swiss-Prot),   A6HME5 (UniProtKB/TrEMBL),   D4A6A2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001104764   ⟸   NM_001111294
- Peptide Label: isoform a
- UniProtKB: Q6URK3 (UniProtKB/Swiss-Prot),   Q6URK4 (UniProtKB/Swiss-Prot),   A6HME5 (UniProtKB/TrEMBL),   D4A6A2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001104765   ⟸   NM_001111295
- Peptide Label: isoform b
- UniProtKB: A6HME9 (UniProtKB/TrEMBL),   D4A6A2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008760134   ⟸   XM_008761912
- Peptide Label: isoform X3
- UniProtKB: A6HME9 (UniProtKB/TrEMBL),   D4A6A2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008760133   ⟸   XM_008761911
- Peptide Label: isoform X3
- UniProtKB: A6HME9 (UniProtKB/TrEMBL),   D4A6A2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069876   ⟸   ENSRNOT00000078872
Ensembl Acc Id: ENSRNOP00000079420   ⟸   ENSRNOT00000097068
Ensembl Acc Id: ENSRNOP00000084090   ⟸   ENSRNOT00000114122
Ensembl Acc Id: ENSRNOP00000079754   ⟸   ENSRNOT00000100893
RefSeq Acc Id: XP_063140201   ⟸   XM_063284131
- Peptide Label: isoform X1
- UniProtKB: Q6URK4 (UniProtKB/Swiss-Prot),   Q6URK3 (UniProtKB/Swiss-Prot),   A6HME5 (UniProtKB/TrEMBL),   D4A6A2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140204   ⟸   XM_063284134
- Peptide Label: isoform X3
- UniProtKB: A6HME9 (UniProtKB/TrEMBL),   D4A6A2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140202   ⟸   XM_063284132
- Peptide Label: isoform X2
Protein Domains
RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6URK4-F1-model_v2 AlphaFold Q6URK4 1-379 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692152
Promoter ID:EPDNEW_R2677
Type:multiple initiation site
Name:Hnrnpa3_1
Description:heterogeneous nuclear ribonucleoprotein A3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0362,481,266 - 62,481,326EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:727807 AgrOrtholog
BioCyc Gene G2FUF-49303 BioCyc
Ensembl Genes ENSRNOG00000027006 UniProtKB/TrEMBL
  ENSRNOG00000052968 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055020888 UniProtKB/Swiss-Prot
  ENSRNOG00060015312 UniProtKB/Swiss-Prot
  ENSRNOG00065016953 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000035567.7 UniProtKB/TrEMBL
  ENSRNOT00000078872.2 UniProtKB/Swiss-Prot
  ENSRNOT00000097068.1 UniProtKB/TrEMBL
  ENSRNOT00000100893.1 UniProtKB/TrEMBL
  ENSRNOT00000114122.1 UniProtKB/TrEMBL
  ENSRNOT00055035647 UniProtKB/Swiss-Prot
  ENSRNOT00060026256 UniProtKB/Swiss-Prot
  ENSRNOT00065028292 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7108128 IMAGE-MGC_LOAD
InterPro HnRNPA1_C UniProtKB/TrEMBL
  hnRNPA3_RRM1 UniProtKB/TrEMBL
  hnRNPA3_RRM2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:362152 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:93744 IMAGE-MGC_LOAD
NCBI Gene 362152 ENTREZGENE
PANTHER HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam HnRNPA1 UniProtKB/TrEMBL
  RRM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hnrnpa3 PhenoGen
PROSITE RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000027006 RatGTEx
  ENSRNOG00000052968 RatGTEx
  ENSRNOG00055020888 RatGTEx
  ENSRNOG00060015312 RatGTEx
  ENSRNOG00065016953 RatGTEx
SMART RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZMP2_RAT UniProtKB/TrEMBL
  A0A8I5ZNL7_RAT UniProtKB/TrEMBL
  A0A8I5ZY44_RAT UniProtKB/TrEMBL
  A6HME5 ENTREZGENE, UniProtKB/TrEMBL
  A6HME9 ENTREZGENE, UniProtKB/TrEMBL
  D4A6A2 ENTREZGENE, UniProtKB/TrEMBL
  Q6URK3 ENTREZGENE
  Q6URK4 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q6URK3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-05-19 Hnrnpa3  heterogeneous nuclear ribonucleoprotein A3  Hnrpa3  heterogeneous nuclear ribonucleoprotein A3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Hnrpa3  heterogeneous nuclear ribonucleoprotein A3  hnRNPA3    Symbol updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization protein localizes to the nucleus and to cytoplasmic transport granules in the neurites of cultured hippocampal neurons 625404
gene_expression the larger two alternative transcripts are expressed most highly in brain, lung and testes 625404
gene_physical_interaction binds to the cis-acting response element, A2RE 625404
gene_transcript alternative splicing produces 4 transcripts giving protiens with apparent molecular masses of 38-, 39-, 41-, and 41.5-kDa 625404