Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Ddb2 (damage specific DNA binding protein 2) Rattus norvegicus
Symbol: Ddb2
Name: damage specific DNA binding protein 2
RGD ID: 1310164
Description: Predicted to contribute to damaged DNA binding activity and ubiquitin-protein transferase activity. Predicted to be involved in DNA repair and protein ubiquitination. Predicted to localize to Cul4B-RING E3 ubiquitin ligase complex; cell junction; and nucleoplasm. Human ortholog(s) of this gene implicated in xeroderma pigmentosum and xeroderma pigmentosum group E. Orthologous to human DDB2 (damage specific DNA binding protein 2); PARTICIPATES IN nucleotide excision repair pathway; INTERACTS WITH (+)-schisandrin B; acetamide; tetrachloromethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DNA damage-binding protein 2; LOC100362121; LOC311186
Homo sapiens (human) : DDB2 (damage specific DNA binding protein 2)  HGNC  Alliance
Mus musculus (house mouse) : Ddb2 (damage specific DNA binding protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ddb2 (damage specific DNA binding protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : DDB2 (damage specific DNA binding protein 2)
Canis lupus familiaris (dog) : DDB2 (damage specific DNA binding protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ddb2 (damage specific DNA binding protein 2)
Sus scrofa (pig) : DDB2 (damage specific DNA binding protein 2)
Chlorocebus sabaeus (African green monkey) : DDB2 (damage specific DNA binding protein 2)
Heterocephalus glaber (naked mole-rat) : Ddb2 (damage specific DNA binding protein 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0380,030,437 - 80,052,984 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl380,030,437 - 80,052,953 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0386,739,190 - 86,761,746 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4375,568,487 - 75,591,428 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1375,464,444 - 75,487,924 (-)NCBI
Celera376,393,455 - 76,415,828 (-)NCBICelera
Cytogenetic Map3q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Ddb2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310164
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.