Ddb2 (damage specific DNA binding protein 2)

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Gene: Ddb2 (damage specific DNA binding protein 2) Rattus norvegicus

Analyze

Symbol:

Ddb2

Name:

damage specific DNA binding protein 2

RGD ID:

1310164

Description:

Predicted to contribute to damaged DNA binding activity and ubiquitin-protein transferase activity. Predicted to be involved in DNA repair and protein ubiquitination. Predicted to act upstream of or within pyrimidine dimer repair. Predicted to be located in cell junction and nucleoplasm. Predicted to be part of Cul4A-RING E3 ubiquitin ligase complex and Cul4B-RING E3 ubiquitin ligase complex. Predicted to be active in nucleus and site of DNA damage. Human ortholog(s) of this gene implicated in xeroderma pigmentosum and xeroderma pigmentosum group E. Orthologous to human DDB2 (damage specific DNA binding protein 2); PARTICIPATES IN nucleotide excision repair pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

DNA damage-binding protein 2; LOC100362121; LOC311186

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	77,185,114 - 77,207,650 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	77,185,109 - 77,207,631 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	80,663,452 - 80,685,994 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	3	89,262,459 - 89,284,999 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	3	87,113,528 - 87,135,968 (-)	NCBI	Rnor_WKY
Rnor_6.0	3	80,030,437 - 80,052,984 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	80,030,437 - 80,052,953 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	86,739,190 - 86,761,746 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	75,568,487 - 75,591,428 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	75,464,444 - 75,487,924 (-)	NCBI
Celera	3	76,393,455 - 76,415,828 (-)	NCBI		Celera
Cytogenetic Map	3	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

congenital disorder of glycosylation type IIc (ISO)

fetal akinesia deformation sequence syndrome 1 (ISO)

genetic disease (ISO)

hypertrophic cardiomyopathy (ISO)

intellectual disability (ISO)

xeroderma pigmentosum (ISO)

xeroderma pigmentosum group E (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(R)-mevalonic acid (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-D (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

4-nitrophenol (ISO)

5-aza-2'-deoxycytidine (ISO)

5-fluorouracil (ISO)

acetamide (EXP)

adefovir pivoxil (ISO)

aflatoxin B1 (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

belinostat (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

cadmium dichloride (ISO)

calcitriol (ISO)

carbon nanotube (ISO)

cidofovir anhydrous (ISO)

cisplatin (ISO)

clodronic acid (ISO)

cobalt dichloride (ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

coumestrol (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

decabromodiphenyl ether (ISO)

deoxynivalenol (ISO)

diarsenic trioxide (ISO)

dibenzo[a,l]pyrene (ISO)

dibutyl phthalate (ISO)

dimethylarsinic acid (ISO)

dioxygen (ISO)

dorsomorphin (ISO)

Enterolactone (ISO)

ethyl methanesulfonate (ISO)

fluvastatin (ISO)

formaldehyde (ISO)

hydrogen peroxide (ISO)

hydroxyurea (ISO)

irinotecan (ISO)

ivermectin (ISO)

leflunomide (ISO)

lycopene (ISO)

methyl methanesulfonate (ISO)

methylarsonic acid (ISO)

mitomycin C (ISO)

morphine (ISO)

naloxone (ISO)

nimustine (ISO)

Nonidet P-40 (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

paraquat (ISO)

parathion (ISO)

perfluorooctanoic acid (ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

piroxicam (ISO)

potassium bromate (ISO)

quercetin (ISO)

resveratrol (EXP,ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

sulforaphane (ISO)

sunitinib (ISO)

T-2 toxin (ISO)

tert-butyl hydroperoxide (ISO)

testosterone (ISO)

tetrachloromethane (EXP,ISO)

tetraphene (ISO)

thioacetamide (EXP)

trichloroethene (EXP)

trichostatin A (ISO)

tris(2-butoxyethyl) phosphate (ISO)

urethane (ISO)

valproic acid (ISO)

vorinostat (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

cellular response to UV (ISO)

DNA damage response (ISO)

DNA repair (IBA)

histone H2A monoubiquitination (ISO)

nucleotide-excision repair (ISO)

protein autoubiquitination (ISO)

protein polyubiquitination (ISO)

pyrimidine dimer repair (ISO)

response to UV (IBA,ISO)

UV-damage excision repair (ISO)

Cellular Component

cell junction (IEA,ISO)

cellular_component (ND)

Cul4-RING E3 ubiquitin ligase complex (ISO)

Cul4A-RING E3 ubiquitin ligase complex (ISO)

Cul4B-RING E3 ubiquitin ligase complex (ISO)

nucleoplasm (IEA,ISO)

nucleus (IBA,ISO)

protein-containing complex (ISO)

site of DNA damage (ISO)

Molecular Function

damaged DNA binding (IBA,ISO)

molecular_function (ND)

protein binding (ISO)

protein-containing complex binding (ISO)

ubiquitin-protein transferase activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

nucleotide excision repair pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	TFIIH: when transcription met DNA repair.	Compe E and Egly JM, Nat Rev Mol Cell Biol. 2012 May 10;13(6):343-54. doi: 10.1038/nrm3350.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Mutations specific to the xeroderma pigmentosum group E Ddb- phenotype.	Nichols AF, etal., J Biol Chem. 1996 Oct 4;271(40):24317-20.
6.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
7.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
9.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:11564863	PMID:12732143	PMID:15558025	PMID:16949367	PMID:22334663

Genomics

Comparative Map Data

Ddb2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	77,185,114 - 77,207,650 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	77,185,109 - 77,207,631 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	80,663,452 - 80,685,994 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	3	89,262,459 - 89,284,999 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	3	87,113,528 - 87,135,968 (-)	NCBI	Rnor_WKY
Rnor_6.0	3	80,030,437 - 80,052,984 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	80,030,437 - 80,052,953 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	86,739,190 - 86,761,746 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	75,568,487 - 75,591,428 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	75,464,444 - 75,487,924 (-)	NCBI
Celera	3	76,393,455 - 76,415,828 (-)	NCBI		Celera
Cytogenetic Map	3	q24	NCBI

DDB2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	47,214,454 - 47,239,217 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	11	47,214,465 - 47,239,217 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	47,236,005 - 47,260,768 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	47,193,089 - 47,217,339 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	47,193,088 - 47,217,339	NCBI
Celera	11	47,375,719 - 47,399,996 (+)	NCBI		Celera
Cytogenetic Map	11	p11.2	NCBI
HuRef	11	46,935,465 - 46,959,749 (+)	NCBI		HuRef
CHM1_1	11	47,235,200 - 47,259,461 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	47,371,205 - 47,395,960 (+)	NCBI		T2T-CHM13v2.0

Ddb2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	91,041,924 - 91,067,465 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	91,041,917 - 91,067,327 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	91,211,545 - 91,237,132 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	91,211,572 - 91,236,982 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	91,051,736 - 91,077,223 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	91,012,695 - 91,037,821 (-)	NCBI		MGSCv36	mm8
Celera	2	92,597,053 - 92,622,532 (-)	NCBI		Celera
Cytogenetic Map	2	E1	NCBI

Ddb2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	961,893 - 974,338 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955422	961,602 - 977,066 (-)	NCBI	ChiLan1.0	ChiLan1.0

DDB2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	11	47,714,723 - 47,738,761 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	47,714,723 - 47,738,761 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	11	47,161,345 - 47,185,526 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

DDB2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	42,354,201 - 42,378,463 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	42,354,572 - 42,377,947 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	41,082,901 - 41,121,019 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	43,008,693 - 43,046,571 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	43,009,064 - 43,031,978 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	42,494,741 - 42,532,869 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	42,050,170 - 42,087,817 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	42,779,573 - 42,817,722 (-)	NCBI		UU_Cfam_GSD_1.0

Ddb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	19,848,763 - 19,863,184 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936562	1,960,406 - 1,974,867 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936562	1,960,406 - 1,974,809 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DDB2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	15,337,743 - 15,383,120 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	15,342,614 - 15,370,623 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	16,566,180 - 16,592,528 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DDB2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	18,071,011 - 18,096,660 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	18,071,383 - 18,096,595 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	115,374,370 - 115,399,306 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ddb2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624767	1,481,447 - 1,492,467 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624767	1,481,151 - 1,495,073 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ddb2
106 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	364
Count of miRNA genes:	196
Interacting mature miRNAs:	225
Transcripts:	ENSRNOT00000018998, ENSRNOT00000057180
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2290452	Scl56	Serum cholesterol level QTL 56	2.26		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	3	1	91609953	Rat
1358905	Hrtrt17	Heart rate QTL 17	5.9	0.000014	heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	10861912	89878372	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	29463235	118376539	Rat
61419	Cia11	Collagen induced arthritis QTL 11	5.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	3	30356773	98535386	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	31172320	163586636	Rat
1354589	Bw31	Body weight QTL 31	3.3		body mass (VT:0001259)	body weight (CMO:0000012)	3	33703347	78196190	Rat
1354604	Bw36	Body weight QTL 36	2.9		body mass (VT:0001259)	body weight (CMO:0000012)	3	33703347	104104347	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	38192233	133483320	Rat
738019	Anxrr10	Anxiety related response QTL 10	3.9		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	3	38517803	83517803	Rat
1331777	Bw24	Body weight QTL 24	3.503		body mass (VT:0001259)	body weight (CMO:0000012)	3	39454637	89115240	Rat
1331795	Rf30	Renal function QTL 30	3.708		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	3	39454637	89115240	Rat
1354597	Kidm13	Kidney mass QTL 13	2.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	3	41874578	104104347	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	41874578	155617519	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	41874578	155617519	Rat
1300178	Hrtrt4	Heart rate QTL 4	3.74		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	43827364	90905114	Rat
1581503	Cm58	Cardiac mass QTL 58	2.7	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	43827364	121056321	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	43827364	169034231	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	47233211	147415807	Rat
1358186	Ept2	Estrogen-induced pituitary tumorigenesis QTL 2	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	47233430	110362260	Rat
2292613	Ept16	Estrogen-induced pituitary tumorigenesis QTL 16	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	47233430	110362260	Rat
631665	Bw8	Body weight QTL 8	5.5		body mass (VT:0001259)	body weight (CMO:0000012)	3	50437042	119183768	Rat
724523	Tsu1	Thymus enlargement suppressive QTL 1	3.84		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	3	50437504	115638231	Rat
1582218	Bw74	Body weight QTL 74	3.9	0.0021	body mass (VT:0001259)	body weight (CMO:0000012)	3	53184593	115665732	Rat
1582238	Bw68	Body weight QTL 68	3.2	0.0064	body mass (VT:0001259)	body weight (CMO:0000012)	3	53184593	115665732	Rat
1582239	Epfw1	Epididymal fat weight QTL 1	4.5	0.0006	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	3	53184593	115665732	Rat
61377	Edpm3	Estrogen-dependent pituitary mass QTL 3	7.05	0.038	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	53184692	89878207	Rat
731180	Bp152	Blood pressure QTL 152		0.03	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	53781112	91609953	Rat
731180	Bp152	Blood pressure QTL 152		0.03	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	3	53781112	91609953	Rat
731180	Bp152	Blood pressure QTL 152		0.03	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	53781112	91609953	Rat
1581568	Rf53	Renal function QTL 53			urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	3	56395968	161299569	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	59242096	157323038	Rat
1300111	Rf12	Renal function QTL 12	3.78		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	61017749	121056321	Rat
631200	Cm25	Cardiac mass QTL 25	4.8	0.0001	heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	3	61134348	89115068	Rat
1582210	Bw71	Body weight QTL 71	3.3	0.0012	body mass (VT:0001259)	body weight (CMO:0000012)	3	64655305	115665732	Rat
1582221	Kidm30	Kidney mass QTL 30	3.5	0.0008	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	3	64655305	115665732	Rat
12879848	Bw181	Body weght QTL 181		0.015	body mass (VT:0001259)	body weight (CMO:0000012)	3	70348525	121056321	Rat
2301414	Kidm37	Kidney mass QTL 37		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	70653097	121056321	Rat
1600376	Arunc5	Aerobic running capacity QTL 5		0.21	exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	3	73376539	118376539	Rat

Markers in Region

RH131014

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	77,185,232 - 77,185,417 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	80,030,556 - 80,030,740	NCBI	Rnor6.0
Rnor_5.0	3	86,739,309 - 86,739,493	UniSTS	Rnor5.0
RGSC_v3.4	3	75,568,606 - 75,568,790	UniSTS	RGSC3.4
Celera	3	76,393,574 - 76,393,758	UniSTS
Cytogenetic Map	3	q24	UniSTS

RH133780

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	77,187,185 - 77,187,366 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	80,032,509 - 80,032,689	NCBI	Rnor6.0
Rnor_5.0	3	86,741,262 - 86,741,442	UniSTS	Rnor5.0
RGSC_v3.4	3	75,570,559 - 75,570,739	UniSTS	RGSC3.4
Celera	3	76,395,526 - 76,395,706	UniSTS
Cytogenetic Map	3	q24	UniSTS

RH140075

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	77,197,406 - 77,197,603 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	80,042,730 - 80,042,926	NCBI	Rnor6.0
Rnor_5.0	3	86,751,483 - 86,751,679	UniSTS	Rnor5.0
RGSC_v3.4	3	75,580,780 - 75,580,976	UniSTS	RGSC3.4
Celera	3	76,405,723 - 76,405,919	UniSTS
Cytogenetic Map	3	q24	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	1		11	1	12	1			2	12	28	10
Low	2	43	46	40	7	40	8	11	72	23	13	1	8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001271346	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006234498	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006234499	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039104084	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039104085	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_242065	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005501747	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ228020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000118	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000018998 ⟹ ENSRNOP00000018998

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	77,185,114 - 77,207,631 (-)	Ensembl
Rnor_6.0 Ensembl	3	80,030,437 - 80,052,953 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000116717 ⟹ ENSRNOP00000082625

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	77,185,109 - 77,207,631 (-)	Ensembl

RefSeq Acc Id:

NM_001271346 ⟹ NP_001258275

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	77,185,114 - 77,207,631 (-)	NCBI
Rnor_6.0	3	80,030,437 - 80,052,953 (-)	NCBI
Rnor_5.0	3	86,739,190 - 86,761,746 (-)	NCBI
Celera	3	76,393,455 - 76,415,828 (-)	NCBI

Sequence:

show sequence

AAAAGTAAAGCAGCCCTAGGAGAGTTTGGCGCGAAGTTGTCTGTGCCAAGCTACCTGCGACGAC
GGCGCTCCTTCGTACGTAGTCCCTTCCTGTTTTTCTCCTTCGAGGCTTTTCAGGTCTTGCTTCG
TTATTTTGCCATAGAGCTTGGTATCTCTTCACCGAGTACGTCATGGCTCCCAAGAAATGCCCAG
AAACCCAGAAGTCCCCCGACGTTGCGGTGCTCCTCAAGAGCAAAAGCCGCAGAAGTCCTCAGGA
GCTGGAGCCCGAAGCCAAGAAGCTGTTTGTGCAGGGTCCCGTTTCTAGTAGGAAATGTGAGTCG
TGCTGCCTTCTGGCAGAGTTGTCCAGCTTGCAGATCCCTCCGAGGAGCAGCAGCATTGTCCGGG
ATCTTTACCAGCAGAAGTTGGGCAAAGCCACCTGGCCGTCACTACAGCAGGGTCTCCAGAAGTC
CTTTTTGCACTCTCTAGCTTCTTACCGGGTATTCCAAAAAGCTGCCCCCTTTGACAGGAGGACA
ACGTCCTTGGCATGGCACCCGACTCATCCCAGTACTTTGGCTGTGGGCTCCAAAGGGGGAGATA
TTATGATCTGGAACTTTGGCATAAAGGACAAACCCATCTTCCTTAAAGGGATTGGAGCTGGAGG
AAGCATCACTGGGCTGAAGTTTAATCATCTCAATACCAACCAGTTTTTTGCCTCCTCAATGGAG
GGAACAACCAGGCTGCAGGATTTTAAAGGCAACATTCTCAGAATTTATACCAGCTCAAACTCTT
GCAAGGTCTGGTTTTGCAGCCTTGATGTTTCTGCCAAGAGCCGAGTGGTGGTTACAGGAGACAA
TATGGGACACGTGATCCTGACGAACACAGATGGCAAGGAGCTTTGGAACCTCAGAATGCACAAA
AAGAAAGTAGCCCATGTGGCCCTGAACCCCTGCTGTGATTGGCTTCTGGCCACAGCCTCCATAG
ATCAAACAGTGAAAATTTGGGACCTGCGCCAAATTAAAGGGAAAGACAGCTTCCTCTTCTCACT
GCCTCACAGGCATCCTGTCAATTCAGCTTGTTTTAGCCCCGATGGAGCTCGGCTCCTGACTACT
GACCAGAACAATGAGATTCGGGTTTACTCTGCCTCCCAGTGGGATAGCCCCCTGAGTCTGATCT
CCCACCCTCACCGCCATTTTCAGCACCTCACACCCATCAAGGCGACCTGGCATTCACGGCACAA
CCTCATTGTTGTGGGCCGATACCCAGATCCTAATCTTAAAAGTTGTGTTCCCTATGAACTAAGG
ACAATAGATGTGTTTGATGGAAGCTCGGGGAAGATGATGTGTCAGCTCTATGATCCAGGATATT
CCGGTATTACTTCGCTCAATGAGTTCAATCCTATGGGAGACACACTGGCTTCTACTATGGGTTA
TCATATTCTCATTTGGAGCCCAGAGGAAGATGGGTCATTGAAAGACCATGAAAGACTATGAAGA
TGGTGTGGGACAGCAACACCTGACCCTGCCTATGGGAGCAGGTTCTGTGAGAGAAGTGGTAGCT
GTTTGTTCACAGGCCAGAAGTACCCAACTCTCAGTGTGGGAGTAGGGGTGCTGGTGGCATGGGA
TACTGTATGGAACTAGGATACTGACATGTTACTGCTCTAGATTTTGCTTCAGAAAATTAAAGAG
TAAACCAGCTACCCTCAGGGTCCCTGCTGTGTCTAGCCTGGAGACCAAGTTCATGCTAGAGCCA
AGGTACTTTCCTTTTTTCTGATGTATAGTAGCAGAATAACCAGGGAATTTTTAAATTTTTATGT
TCATTTTGACATAACCAATAAAAGCATATCTTTTGTATTGAGACCTA

hide sequence

RefSeq Acc Id:

XM_006234498 ⟹ XP_006234560

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	77,185,114 - 77,207,648 (-)	NCBI
Rnor_6.0	3	80,030,437 - 80,052,983 (-)	NCBI
Rnor_5.0	3	86,739,190 - 86,761,746 (-)	NCBI

Sequence:

show sequence

GGGACAGCCCTGAGGGGACAGGGCGGGGCTAAAAGTAAAGCAGCCCTAGGAGAGTTTGGCGCGA
AGTTGTCTGTGCCAAGCTACCTGCGACGACGGCGCTCCTTCGTACGTAGTCCCTTCCTGTTTTT
CTCCTTCGAGGCTTTTCAGGTCTTGCTTCGTTATTTTGCCATAGAGCTTGGTATCTCTTCACCG
AGTACGTCATGGCTCCCAAGAAATGCCCAGAAACCCAGAAGTCCCCCGACGTTGCGGTGCTCCT
CAAGAGCAAAAGCCGCAGAAGTCCTCAGGAGCTGGAGCCCGAAGCCAAGAAGCTGTTTGTGCAG
GGTCCCGAGTTGTCCAGCTTGCAGATCCCTCCGAGGAGCAGCAGCATTGTCCGGGATCTTTACC
AGCAGAAGTTGGGCAAAGCCACCTGGCCGTCACTACAGCAGGGTCTCCAGAAGTCCTTTTTGCA
CTCTCTAGCTTCTTACCGGGTATTCCAAAAAGCTGCCCCCTTTGACAGGAGGACAACGTCCTTG
GCATGGCACCCGACTCATCCCAGTACTTTGGCTGTGGGCTCCAAAGGGGGAGATATTATGATCT
GGAACTTTGGCATAAAGGACAAACCCATCTTCCTTAAAGGGATTGGAGCTGGAGGAAGCATCAC
TGGGCTGAAGTTTAATCATCTCAATACCAACCAGTTTTTTGCCTCCTCAATGGAGGGAACAACC
AGGCTGCAGGATTTTAAAGGCAACATTCTCAGAATTTATACCAGCTCAAACTCTTGCAAGGTCT
GGTTTTGCAGCCTTGATGTTTCTGCCAAGAGCCGAGTGGTGGTTACAGGAGACAATATGGGACA
CGTGATCCTGACGAACACAGATGGCAAGGAGCTTTGGAACCTCAGAATGCACAAAAAGAAAGTA
GCCCATGTGGCCCTGAACCCCTGCTGTGATTGGCTTCTGGCCACAGCCTCCATAGATCAAACAG
TGAAAATTTGGGACCTGCGCCAAATTAAAGGGAAAGACAGCTTCCTCTTCTCACTGCCTCACAG
GCATCCTGTCAATTCAGCTTGTTTTAGCCCCGATGGAGCTCGGCTCCTGACTACTGACCAGAAC
AATGAGATTCGGGTTTACTCTGCCTCCCAGTGGGATAGCCCCCTGAGTCTGATCTCCCACCCTC
ACCGCCATTTTCAGCACCTCACACCCATCAAGGCGACCTGGCATTCACGGCACAACCTCATTGT
TGTGGGCCGATACCCAGATCCTAATCTTAAAAGTTGTGTTCCCTATGAACTAAGGACAATAGAT
GTGTTTGATGGAAGCTCGGGGAAGATGATGTGTCAGCTCTATGATCCAGGATATTCCGGTATTA
CTTCGCTCAATGAGTTCAATCCTATGGGAGACACACTGGCTTCTACTATGGGTTATCATATTCT
CATTTGGAGCCCAGAGGAAGATGGGTCATTGAAAGACCATGAAAGACTATGAAGATGGTGTGGG
ACAGCAACACCTGACCCTGCCTATGGGAGCAGGTTCTGTGAGAGAAGTGGTAGCTGTTTGTTCA
CAGGCCAGAAGTACCCAACTCTCAGTGTGGGAGTAGGGGTGCTGGTGGCATGGGATACTGTATG
GAACTAGGATACTGACATGTTACTGCTCTAGATTTTGCTTCAGAAAATTAAAGAGTAAACCAGC
TACCCTCAGGGTCCCTGCTGTGTCTAGCCTGGAGACCAAGTTCATGCTAGAGCCAAGGTACTTT
CCTTTTTTCTGATGTATAGTAGCAGAATAACCAGGGAATTTTTAAATTTTTATGTTCATTTTGA
CATAACCAATAAAAGCATATCTTTTGTATTGAGACCTA

hide sequence

RefSeq Acc Id:

XM_006234499 ⟹ XP_006234561

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	77,185,114 - 77,207,648 (-)	NCBI
Rnor_6.0	3	80,030,437 - 80,052,984 (-)	NCBI
Rnor_5.0	3	86,739,190 - 86,761,746 (-)	NCBI

Sequence:

show sequence

CGGGACAGCCCTGAGGGGACAGGGCGGGGCTAAAAGTAAAGCAGCCCTAGGAGAGTTTGGCGCG
AAGTTGTCTGTGCCAAGCTACCTGCGACGACGGCGCTCCTTCGTACGTAGTCCCTTCCTGTTTT
TCTCCTTCGAGGCTTTTCAGGTCTTGCTTCGTTATTTTGCCATAGAGCTTGGTATCTCTTCACC
GAGTACGTCATGGCTCCCAAGAAATGCCCAGAAACCCAGAAGTCCCCCGACGTTGCGGTGCTCC
TCAAGAGCAAAAGCCGCAGAAGTCCTCAGGAGCTGGAGCCCGAAGCCAAGAAGCTGTTTGTGCA
GGGTCCCGTTTCTAGTAGGAAATGTGAGTCGTGCTGCCTTCTGGCAGAGTTGTCCAGCTTGCAG
ATCCCTCCGAGGAGCAGCAGCATTGTCCGGGATCTTTACCAGCAGAAGTTGGGCAAAGCCACCT
GGCCGTCACTACAGCAGGGTCTCCAGAAGTCCTTTTTGCACTCTCTAGCTTCTTACCGGGTATT
CCAAAAAGCTGCCCCCTTTGACAGGAGGACAACGTCCTTGGCATGGCACCCGACTCATCCCAGT
ACTTTGGCTGTGGGCTCCAAAGGGGGAGATATTATGATCTGGAACTTTGGCATAAAGGACAAAC
CCATCTTCCTTAAAGGGATTGGAGCTGGAGGAAGCATCACTGGGCTGAAGTTTAATCATCTCAA
TACCAACCAGTTTTTTGCCTCCTCAATGGAGGGAACAACCAGGCTGCAGGATTTTAAAGGCAAC
ATTCTCAGAATTTATACCAGCTCAAACTCTTGCAAGGTCTGGTTTTGCAGCCTTGATGTTTCTG
CCAAGAGCCGAGTGGTGGTTACAGGAGACAATATGGGACACGTGATCCTGACGAACACAGATGG
CAAGGAGCTTTGGAACCTCAGAATGCACAAAAAGAAAGTAGCCCATGTGGCCCTGAACCCCTGC
TGTGATTGGCTTCTGGCCACAGCCTCCATAGATCAAACAGTGAAAATTTGGGACCTGCGCCAAA
TTAAAGGGAAAGACAGCTTCCTCTTCTCACTGCCTCACAGGCATCCTGTCAATTCAGCTTGTTT
TAGCCCCGATGGAGCTCGGCTCCTGACTACTGACCAGAACAATGAGATTCGGGTTTACTCTGCC
TCCCAGTGGGATAGCCCCCTGAGTCTGATCTCCCACCCTCACCGCCATTTTCAGCACCTCACAC
CCATCAAGCTCAATGAGTTCAATCCTATGGGAGACACACTGGCTTCTACTATGGGTTATCATAT
TCTCATTTGGAGCCCAGAGGAAGATGGGTCATTGAAAGACCATGAAAGACTATGAAGATGGTGT
GGGACAGCAACACCTGACCCTGCCTATGGGAGCAGGTTCTGTGAGAGAAGTGGTAGCTGTTTGT
TCACAGGCCAGAAGTACCCAACTCTCAGTGTGGGAGTAGGGGTGCTGGTGGCATGGGATACTGT
ATGGAACTAGGATACTGACATGTTACTGCTCTAGATTTTGCTTCAGAAAATTAAAGAGTAAACC
AGCTACCCTCAGGGTCCCTGCTGTGTCTAGCCTGGAGACCAAGTTCATGCTAGAGCCAAGGTAC
TTTCCTTTTTTCTGATGTATAGTAGCAGAATAACCAGGGAATTTTTAAATTTTTATGTTCATTT
TGACATAACCAATAAAAGCATATCTTTTGTATTGAGACCTA

hide sequence

RefSeq Acc Id:

XM_039104084 ⟹ XP_038960012

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	77,185,921 - 77,207,650 (-)	NCBI

RefSeq Acc Id:

XM_039104085 ⟹ XP_038960013

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	77,185,114 - 77,207,648 (-)	NCBI

RefSeq Acc Id:

XR_005501747

RefSeq Status:

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	77,185,779 - 77,207,650 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001258275	(Get FASTA)	NCBI Sequence Viewer
	XP_006234560	(Get FASTA)	NCBI Sequence Viewer
	XP_006234561	(Get FASTA)	NCBI Sequence Viewer
	XP_038960012	(Get FASTA)	NCBI Sequence Viewer
	XP_038960013	(Get FASTA)	NCBI Sequence Viewer
	XP_242065	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL79518	(Get FASTA)	NCBI Sequence Viewer
	EDL79519	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001258275 ⟸ NM_001271346

- UniProtKB:

D3ZR08 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAPKKCPETQKSPDVAVLLKSKSRRSPQELEPEAKKLFVQGPVSSRKCESCCLLAELSSLQIPP
RSSSIVRDLYQQKLGKATWPSLQQGLQKSFLHSLASYRVFQKAAPFDRRTTSLAWHPTHPSTLA
VGSKGGDIMIWNFGIKDKPIFLKGIGAGGSITGLKFNHLNTNQFFASSMEGTTRLQDFKGNILR
IYTSSNSCKVWFCSLDVSAKSRVVVTGDNMGHVILTNTDGKELWNLRMHKKKVAHVALNPCCDW
LLATASIDQTVKIWDLRQIKGKDSFLFSLPHRHPVNSACFSPDGARLLTTDQNNEIRVYSASQW
DSPLSLISHPHRHFQHLTPIKATWHSRHNLIVVGRYPDPNLKSCVPYELRTIDVFDGSSGKMMC
QLYDPGYSGITSLNEFNPMGDTLASTMGYHILIWSPEEDGSLKDHERL

hide sequence

RefSeq Acc Id:

XP_006234561 ⟸ XM_006234499

- Peptide Label:

isoform X2

- Sequence:

show sequence

MAPKKCPETQKSPDVAVLLKSKSRRSPQELEPEAKKLFVQGPVSSRKCESCCLLAELSSLQIPP
RSSSIVRDLYQQKLGKATWPSLQQGLQKSFLHSLASYRVFQKAAPFDRRTTSLAWHPTHPSTLA
VGSKGGDIMIWNFGIKDKPIFLKGIGAGGSITGLKFNHLNTNQFFASSMEGTTRLQDFKGNILR
IYTSSNSCKVWFCSLDVSAKSRVVVTGDNMGHVILTNTDGKELWNLRMHKKKVAHVALNPCCDW
LLATASIDQTVKIWDLRQIKGKDSFLFSLPHRHPVNSACFSPDGARLLTTDQNNEIRVYSASQW
DSPLSLISHPHRHFQHLTPIKLNEFNPMGDTLASTMGYHILIWSPEEDGSLKDHERL

hide sequence

RefSeq Acc Id:

XP_006234560 ⟸ XM_006234498

- Peptide Label:

isoform X1

- Sequence:

show sequence

MAPKKCPETQKSPDVAVLLKSKSRRSPQELEPEAKKLFVQGPELSSLQIPPRSSSIVRDLYQQK
LGKATWPSLQQGLQKSFLHSLASYRVFQKAAPFDRRTTSLAWHPTHPSTLAVGSKGGDIMIWNF
GIKDKPIFLKGIGAGGSITGLKFNHLNTNQFFASSMEGTTRLQDFKGNILRIYTSSNSCKVWFC
SLDVSAKSRVVVTGDNMGHVILTNTDGKELWNLRMHKKKVAHVALNPCCDWLLATASIDQTVKI
WDLRQIKGKDSFLFSLPHRHPVNSACFSPDGARLLTTDQNNEIRVYSASQWDSPLSLISHPHRH
FQHLTPIKATWHSRHNLIVVGRYPDPNLKSCVPYELRTIDVFDGSSGKMMCQLYDPGYSGITSL
NEFNPMGDTLASTMGYHILIWSPEEDGSLKDHERL

hide sequence

RefSeq Acc Id:

ENSRNOP00000018998 ⟸ ENSRNOT00000018998

RefSeq Acc Id:	XP_038960013 ⟸ XM_039104085
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038960012 ⟸ XM_039104084
- Peptide Label:	isoform X3

RefSeq Acc Id:

ENSRNOP00000082625 ⟸ ENSRNOT00000116717

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZR08-F1-model_v2	AlphaFold	D3ZR08	1-432	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692212

Promoter ID:

EPDNEW_R2735

Type:

single initiation site

Name:

Ddb2_1

Description:

damage specific DNA binding protein 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	80,052,915 - 80,052,975	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310164	AgrOrtholog
BioCyc Gene	G2FUF-48741	BioCyc
Ensembl Genes	ENSRNOG00000014071	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000018998	ENTREZGENE
	ENSRNOP00000018998.4	UniProtKB/TrEMBL
	ENSRNOP00000082625.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000018998	ENTREZGENE
	ENSRNOT00000018998.9	UniProtKB/TrEMBL
	ENSRNOT00000116717.1	UniProtKB/TrEMBL
Gene3D-CATH	2.130.10.10	UniProtKB/TrEMBL
	4.10.640.30	UniProtKB/TrEMBL
InterPro	DDB2	UniProtKB/TrEMBL
	WD40/YVTN_repeat-like_dom	UniProtKB/TrEMBL
	WD40_repeat	UniProtKB/TrEMBL
	WD40_repeat_CS	UniProtKB/TrEMBL
	WD40_repeat_dom_sf	UniProtKB/TrEMBL
KEGG Report	rno:100362121	UniProtKB/TrEMBL
NCBI Gene	Ddb2	ENTREZGENE
OMIM	600811
PANTHER	DNA DAMAGE-BINDING PROTEIN 2	UniProtKB/TrEMBL
	PTHR15169	UniProtKB/TrEMBL
Pfam	WD40	UniProtKB/TrEMBL
PhenoGen	Ddb2	PhenoGen
PROSITE	WD_REPEATS_1	UniProtKB/TrEMBL
	WD_REPEATS_2	UniProtKB/TrEMBL
	WD_REPEATS_REGION	UniProtKB/TrEMBL
SMART	WD40	UniProtKB/TrEMBL
Superfamily-SCOP	WD40_like	UniProtKB/TrEMBL
UniProt	A0A8I5ZXK9_RAT	UniProtKB/TrEMBL
	D3ZR08	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2012-08-27	Ddb2	damage specific DNA binding protein 2	LOC100362121	damage specific DNA binding protein 2	Data Merged	737654	APPROVED
2010-05-05	LOC100362121	damage specific DNA binding protein 2			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-04-30	Ddb2	damage specific DNA binding protein 2	Ddb2_predicted	damage specific DNA binding protein 2 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Ddb2_predicted	damage specific DNA binding protein 2 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

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Imported Disease Annotations - CTD

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RGD Manual Annotations