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Gene: Ddb2 (damage specific DNA binding protein 2) Rattus norvegicus
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Symbol: Ddb2
Name: damage specific DNA binding protein 2
Description: Predicted to contribute to damaged DNA binding activity and ubiquitin-protein transferase activity. Predicted to be involved in DNA metabolic process and cellular protein modification process. Predicted to localize to the Cul4B-RING E3 ubiquitin ligase complex; cell junction; and nucleoplasm. Human ortholog(s) of this gene implicated in xeroderma pigmentosum and xeroderma pigmentosum group E. Orthologous to human DDB2 (damage specific DNA binding protein 2); PARTICIPATES IN nucleotide excision repair pathway; INTERACTS WITH (+)-schisandrin B; tetrachloromethane; (R)-mevalonic acid (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DNA damage-binding protein 2; LOC100362121; LOC311186
Orthologs:
Homo sapiens (human) : DDB2 (damage specific DNA binding protein 2)  HGNC  Alliance
Mus musculus (house mouse) : Ddb2 (damage specific DNA binding protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ddb2 (damage specific DNA binding protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : DDB2 (damage specific DNA binding protein 2)
Canis lupus familiaris (dog) : DDB2 (damage specific DNA binding protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ddb2 (damage specific DNA binding protein 2)
Sus scrofa (pig) : DDB2 (damage specific DNA binding protein 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0380,030,437 - 80,052,984 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0386,739,190 - 86,761,746 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4375,568,487 - 75,591,428 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1375,464,444 - 75,487,924 (-)NCBI
Celera376,393,455 - 76,415,828 (-)NCBICelera
Cytogenetic Map3q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Ddb2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310164
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.