Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Eif3j | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of EIF3J mRNA] | CTD | PMID:31150632 | Eif3j | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Eif3j1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF3J1 mRNA | CTD | PMID:22206623 | Eif3j | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Eif3j1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of EIF3J mRNA | CTD | PMID:17942748 | Eif3j | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Eif3j1 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of EIF3J mRNA | CTD | PMID:17942748 | Eif3j | Rat | 17beta-estradiol | increases expression | ISO | EIF3J (Homo sapiens) | 6480464 | Estradiol results in increased expression of EIF3J mRNA | CTD | PMID:31614463 | Eif3j | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Eif3j1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of EIF3J mRNA | CTD | PMID:17942748 | Eif3j | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Eif3j1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of EIF3J mRNA | CTD | PMID:17942748 and PMID:19465110 | Eif3j | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | EIF3J (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of EIF3J mRNA | CTD | PMID:20106945 and PMID:21632981 | Eif3j | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of EIF3J mRNA | CTD | PMID:21346803 | Eif3j | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | EIF3J (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of EIF3J mRNA | CTD | PMID:30851411 | Eif3j | Rat | 4,4'-diaminodiphenylmethane | decreases expression | EXP | | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of EIF3J mRNA | CTD | PMID:30723492 | Eif3j | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | Eif3j1 (Mus musculus) | 6480464 | bisphenol S results in decreased expression of EIF3J1 mRNA | CTD | PMID:30951980 | Eif3j | Rat | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of EIF3J mRNA | CTD | PMID:36041667 | Eif3j | Rat | 4,4'-sulfonyldiphenol | multiple interactions | ISO | Eif3j1 (Mus musculus) | 6480464 | [bisphenol S co-treated with LIF protein] results in increased expression of EIF3J1 mRNA and [bisphenol S co-treated with Tretinoin] results in increased expression of EIF3J1 mRNA | CTD | PMID:30951980 | Eif3j | Rat | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of EIF3J mRNA | CTD | PMID:31881176 | Eif3j | Rat | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of EIF3J mRNA | CTD | PMID:28959563 | Eif3j | Rat | actinomycin D | multiple interactions | ISO | EIF3J (Homo sapiens) | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased secretion of EIF3J protein | CTD | PMID:38460933 | Eif3j | Rat | aflatoxin B1 | increases expression | ISO | Eif3j1 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of EIF3J mRNA | CTD | PMID:19770486 | Eif3j | Rat | aflatoxin M1 | decreases expression | ISO | EIF3J (Homo sapiens) | 6480464 | Aflatoxin M1 results in decreased expression of EIF3J mRNA | CTD | PMID:30928695 | Eif3j | Rat | all-trans-retinoic acid | multiple interactions | ISO | Eif3j1 (Mus musculus) | 6480464 | [bisphenol A co-treated with Tretinoin] results in increased expression of EIF3J1 mRNA more ... | CTD | PMID:30951980 | Eif3j | Rat | all-trans-retinoic acid | decreases expression | ISO | EIF3J (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of EIF3J mRNA | CTD | PMID:33167477 | Eif3j | Rat | benzo[a]pyrene | increases expression | ISO | Eif3j1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of EIF3J mRNA | CTD | PMID:22228805 | Eif3j | Rat | benzo[a]pyrene | increases methylation | ISO | EIF3J (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of EIF3J promoter | CTD | PMID:27901495 | Eif3j | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of EIF3J mRNA | CTD | PMID:25181051 | Eif3j | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of EIF3J mRNA | CTD | PMID:36041667 | Eif3j | Rat | bisphenol A | increases expression | ISO | Eif3j1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of EIF3J1 mRNA | CTD | PMID:33221593 | Eif3j | Rat | bisphenol A | multiple interactions | ISO | Eif3j1 (Mus musculus) | 6480464 | [bisphenol A co-treated with LIF protein] affects the expression of EIF3J1 mRNA and [bisphenol A co-treated with Tretinoin] results in increased expression of EIF3J1 mRNA | CTD | PMID:30951980 | Eif3j | Rat | bisphenol A | affects expression | ISO | EIF3J (Homo sapiens) | 6480464 | bisphenol A affects the expression of EIF3J mRNA | CTD | PMID:30903817 | Eif3j | Rat | bisphenol A | decreases expression | ISO | Eif3j1 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of EIF3J1 mRNA | CTD | PMID:30951980 | Eif3j | Rat | bisphenol A | decreases expression | ISO | EIF3J (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of EIF3J mRNA | CTD | PMID:29275510 | Eif3j | Rat | bisphenol F | multiple interactions | ISO | Eif3j1 (Mus musculus) | 6480464 | [bisphenol F co-treated with Tretinoin] results in increased expression of EIF3J1 mRNA | CTD | PMID:30951980 | Eif3j | Rat | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of EIF3J mRNA | CTD | PMID:36041667 | Eif3j | Rat | Brodifacoum | increases expression | EXP | | 6480464 | bromfenacoum results in increased expression of EIF3J protein | CTD | PMID:28903499 | Eif3j | Rat | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of EIF3J mRNA | CTD | PMID:33453195 | Eif3j | Rat | caffeine | affects phosphorylation | ISO | EIF3J (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of EIF3J protein | CTD | PMID:35688186 | Eif3j | Rat | carbon nanotube | increases expression | ISO | Eif3j1 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25620056 | Eif3j | Rat | chromium(6+) | affects expression | ISO | Eif3j1 (Mus musculus) | 6480464 | chromium hexavalent ion affects the expression of EIF3J1 mRNA | CTD | PMID:28472532 | Eif3j | Rat | cisplatin | multiple interactions | ISO | EIF3J (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of EIF3J mRNA | CTD | PMID:27392435 | Eif3j | Rat | clozapine | increases expression | ISO | EIF3J (Homo sapiens) | 6480464 | Clozapine results in increased expression of EIF3J protein | CTD | PMID:34122009 | Eif3j | Rat | copper(II) sulfate | increases expression | ISO | EIF3J (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of EIF3J mRNA | CTD | PMID:19549813 | Eif3j | Rat | cyclosporin A | increases expression | ISO | EIF3J (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of EIF3J mRNA | CTD | PMID:20106945 more ... | Eif3j | Rat | Dibutyl phosphate | affects expression | ISO | EIF3J (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of EIF3J mRNA | CTD | PMID:37042841 | Eif3j | Rat | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of EIF3J mRNA | CTD | PMID:17379624 | Eif3j | Rat | folic acid | multiple interactions | ISO | Eif3j1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EIF3J1 mRNA | CTD | PMID:22206623 | Eif3j | Rat | FR900359 | affects phosphorylation | ISO | EIF3J (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of EIF3J protein | CTD | PMID:37730182 | Eif3j | Rat | hydrogen peroxide | affects expression | ISO | EIF3J (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of EIF3J mRNA | CTD | PMID:20044591 | Eif3j | Rat | ivermectin | decreases expression | ISO | EIF3J (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of EIF3J protein | CTD | PMID:32959892 | Eif3j | Rat | lipopolysaccharide | multiple interactions | ISO | EIF3J (Homo sapiens) | 6480464 | [NAT10 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of EIF3J mRNA | CTD | PMID:35877022 | Eif3j | Rat | menadione | affects expression | ISO | EIF3J (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of EIF3J mRNA | CTD | PMID:20044591 | Eif3j | Rat | N-ethyl-N-nitrosourea | increases mutagenesis | ISO | Eif3j1 (Mus musculus) | 6480464 | Ethylnitrosourea results in increased mutagenesis of EIF3J gene | CTD | PMID:27776689 | Eif3j | Rat | Nutlin-3 | multiple interactions | ISO | EIF3J (Homo sapiens) | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased secretion of EIF3J protein | CTD | PMID:38460933 | Eif3j | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of EIF3J mRNA | CTD | PMID:25729387 | Eif3j | Rat | paracetamol | affects expression | ISO | Eif3j1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of EIF3J mRNA | CTD | PMID:17562736 | Eif3j | Rat | perfluorohexanesulfonic acid | decreases expression | ISO | EIF3J (Homo sapiens) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of EIF3J mRNA | CTD | PMID:25812627 | Eif3j | Rat | perfluorohexanesulfonic acid | decreases expression | ISO | Eif3j1 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of EIF3J1 mRNA | CTD | PMID:37995155 | Eif3j | Rat | perfluorooctane-1-sulfonic acid | increases expression | ISO | EIF3J (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in increased expression of EIF3J mRNA | CTD | PMID:25812627 | Eif3j | Rat | perfluorooctanoic acid | increases expression | ISO | EIF3J (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of EIF3J mRNA and perfluorooctanoic acid results in increased expression of EIF3J protein | CTD | PMID:25812627 and PMID:26879310 | Eif3j | Rat | phenobarbital | affects expression | ISO | EIF3J (Homo sapiens) | 6480464 | Phenobarbital affects the expression of EIF3J mRNA | CTD | PMID:19159669 | Eif3j | Rat | pirinixic acid | increases expression | ISO | Eif3j1 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of EIF3J mRNA | CTD | PMID:23811191 | Eif3j | Rat | piroxicam | decreases expression | ISO | EIF3J (Homo sapiens) | 6480464 | Piroxicam results in decreased expression of EIF3J mRNA | CTD | PMID:21858171 | Eif3j | Rat | propiconazole | increases expression | ISO | Eif3j1 (Mus musculus) | 6480464 | propiconazole results in increased expression of EIF3J mRNA | CTD | PMID:21278054 | Eif3j | Rat | rac-lactic acid | decreases expression | ISO | EIF3J (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of EIF3J mRNA | CTD | PMID:30851411 | Eif3j | Rat | resveratrol | multiple interactions | ISO | EIF3J (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of EIF3J mRNA | CTD | PMID:23557933 | Eif3j | Rat | sodium arsenite | multiple interactions | ISO | EIF3J (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of and results in increased activity of EIF3J protein | CTD | PMID:30528433 | Eif3j | Rat | sodium arsenite | increases expression | ISO | Eif3j1 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of EIF3J1 mRNA | CTD | PMID:37682722 | Eif3j | Rat | T-2 toxin | increases expression | EXP | | 6480464 | T-2 Toxin results in increased expression of EIF3J mRNA | CTD | PMID:26141394 | Eif3j | Rat | temozolomide | increases expression | ISO | EIF3J (Homo sapiens) | 6480464 | Temozolomide results in increased expression of EIF3J mRNA | CTD | PMID:31758290 | Eif3j | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of EIF3J mRNA] | CTD | PMID:31150632 | Eif3j | Rat | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of EIF3J mRNA | CTD | PMID:31150632 | Eif3j | Rat | tetraphene | decreases expression | ISO | Eif3j1 (Mus musculus) | 6480464 | benz(a)anthracene results in decreased expression of EIF3J mRNA | CTD | PMID:26377693 | Eif3j | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of EIF3J mRNA | CTD | PMID:34492290 | Eif3j | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of EIF3J mRNA | CTD | PMID:25729387 | Eif3j | Rat | trichloroethene | decreases expression | ISO | Eif3j1 (Mus musculus) | 6480464 | Trichloroethylene results in decreased expression of EIF3J mRNA | CTD | PMID:19448997 | Eif3j | Rat | triphenyl phosphate | affects expression | ISO | EIF3J (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of EIF3J mRNA | CTD | PMID:37042841 | Eif3j | Rat | valproic acid | affects expression | ISO | Eif3j1 (Mus musculus) | 6480464 | Valproic Acid affects the expression of EIF3J mRNA | CTD | PMID:17963808 | Eif3j | Rat | valproic acid | increases expression | ISO | EIF3J (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of EIF3J mRNA | CTD | PMID:23179753 | Eif3j | Rat | valproic acid | affects expression | ISO | EIF3J (Homo sapiens) | 6480464 | Valproic Acid affects the expression of EIF3J mRNA | CTD | PMID:25979313 | Eif3j | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of EIF3J mRNA | CTD | PMID:23034163 | |