Gene: Itga4 (integrin subunit alpha 4) Rattus norvegicus
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Symbol: Itga4
Name: integrin subunit alpha 4
Description: ENCODES a protein that exhibits antigen binding; cell adhesion molecule binding; fibronectin binding; INVOLVED IN axonogenesis involved in innervation; cellular response to cytokine stimulus; clathrin-dependent extracellular exosome endocytosis; PARTICIPATES IN altered integrin mediated signaling pathway; integrin mediated signaling pathway; pancreatic cancer pathway; ASSOCIATED WITH anti-basement membrane glomerulonephritis; diabetic retinopathy; Experimental Arthritis; FOUND IN cell surface; extracellular exosome; growth cone; INTERACTS WITH (+)-pilocarpine; 17alpha-ethynylestradiol; 3-chloropropane-1,2-diol
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: integrin alpha 4; integrin alpha 4 (mapped); integrin alpha-4; integrin, alpha 4; Itga4_mapped
Orthologs:
Homo sapiens (human) : ITGA4 (integrin subunit alpha 4)  HGNC  Alliance
Mus musculus (house mouse) : Itga4 (integrin alpha 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itga4 (integrin subunit alpha 4)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGA4 (integrin subunit alpha 4)
Canis lupus familiaris (dog) : ITGA4 (integrin subunit alpha 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itga4 (integrin subunit alpha 4)
Sus scrofa (pig) : ITGA4 (integrin subunit alpha 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0366,178,745 - 66,265,547 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0372,754,339 - 72,825,872 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4362,024,747 - 62,097,456 (+)NCBIRGSC3.4rn4RGSC3.4
Celera363,623,691 - 63,694,098 (+)NCBICelera
Cytogenetic Map3q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Itga4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1593249
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-02-05
Status: ACTIVE