Gene: Lrp4 (LDL receptor related protein 4) Rattus norvegicus
Symbol: Lrp4
Name: LDL receptor related protein 4
Description: ENCODES a protein that exhibits apolipoprotein binding; receptor tyrosine kinase binding; scaffold protein binding; INVOLVED IN dendrite morphogenesis; protein heterotetramerization; synapse organization; PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; ASSOCIATED WITH Cenani-Lenz syndactyly syndrome (ortholog); congenital myasthenic syndrome (ortholog); congenital myasthenic syndrome 17 (ortholog); FOUND IN cell surface; dendrite; neuronal cell body; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil
Type: protein-coding
Also known as: low density lipoprotein receptor-related protein 4; low-density lipoprotein receptor-related protein 4; LRP-4; Megf7; multiple epidermal growth factor-like domains 7
Homo sapiens (human) : LRP4 (LDL receptor related protein 4)  HGNC  Alliance
Mus musculus (house mouse) : Lrp4 (low density lipoprotein receptor-related protein 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lrp4 (LDL receptor related protein 4)
Pan paniscus (bonobo/pygmy chimpanzee) : LRP4 (LDL receptor related protein 4)
Canis lupus familiaris (dog) : LRP4 (LDL receptor related protein 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lrp4 (LDL receptor related protein 4)
Sus scrofa (pig) : LRP4 (LDL receptor related protein 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0380,362,643 - 80,416,684 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0387,062,818 - 87,116,798 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4375,821,638 - 75,875,100 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1375,718,009 - 75,771,472 (+)NCBI
Celera376,634,746 - 76,688,537 (+)NCBICelera
Cytogenetic Map3q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Lrp4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619731
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-02-05
Status: ACTIVE