 Gene-Chemical Interaction Annotations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology AnnotationsMolecular Pathway Annotations |
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Analyze GeneStrainQTL List |
 Gene Annotator (Functional Annotation) unavailable |
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Gene Annotator (Functional Annotation) |
Gene Annotator (Annotation Distribution) |
Variant Visualizer (Genomic Variants) |
 InterViewer (Protein-Protein Interactions) unavailable |
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 Gene Annotator (Annotation Comparison) unavailable |
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Gene Annotator (Annotation Comparison) |
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MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
Gene Ontology AnnotationsMolecular Pathway AnnotationsDisease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology AnnotationsBiological Process
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Cellular Component
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Molecular Function
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Molecular Pathway AnnotationsReferences - curated| 1. | Bull R, etal., J Neurosci. 2008 Sep 17;28(38):9463-72. |
| 2. | Clark JH, etal., J Biol Chem. 2010 Apr 30;285(18):13542-9. doi: 10.1074/jbc.M110.101485. Epub 2010 Feb 21. |
| 3. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 4. | GOA data from the GO Consortium |
| 5. | Lanner JT, etal., Cold Spring Harb Perspect Biol. 2010 Nov;2(11):a003996. doi: 10.1101/cshperspect.a003996. Epub 2010 Oct 20. |
| 6. | Mironneau J, etal., J Biol Chem 2001 Apr 6;276(14):11257-64. |
| 7. | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 8. | Pipeline to import KEGG annotations from KEGG into RGD |
| 9. | RGD automated data pipeline |
| 10. | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 11. | RGD automated import pipeline for gene-chemical interactions |
References - uncuratedGenomics
Comparative Map Data| Ryr3 (Rattus norvegicus - Norway rat) |
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| RYR3 (Homo sapiens - human) |
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| Ryr3 (Mus musculus - house mouse) |
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| Ryr3 (Chinchilla lanigera - long-tailed chinchilla) |
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| RYR3 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| RYR3 (Canis lupus familiaris - dog) |
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| Ryr3 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| RYR3 (Sus scrofa - pig) |
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| RYR3 (Chlorocebus sabaeus - African green monkey) |
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| Ryr3 (Heterocephalus glaber - naked mole-rat) |
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Position Markers| D3Rat73 |
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| D3Rat287 |
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| D3Got51 |
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| RH144535 |
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| D38218 |
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| BE101798 |
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| AI072496 |
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| AW526786 |
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| BE120119 |
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| RH138135 |
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| Ryr3 |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
Predicted Target Of
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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Expression
RNA-SEQ ExpressionHigh: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM
| alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
| High | |||||||||||||
| Medium | 24 | 4 | 7 | ||||||||||
| Low | 3 | 41 | 17 | 1 | 19 | 1 | 8 | 9 | 50 | 20 | 32 | 4 | 8 |
| Below cutoff | 2 | 17 | 17 | 17 | 2 | 11 | 5 |
View RNA-SEQ Expression Data
Sequence
Nucleotide Sequences| RefSeq Transcripts | XM_017592338 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_017601129 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AABR07053394 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AABR07053395 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07053396 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07053397 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07053398 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07053399 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07053400 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07053401 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AABR07053402 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01024331 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01024332 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01024333 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01024334 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01024335 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01024336 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01024337 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01024338 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01024339 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01024340 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01024341 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01024342 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01024343 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01024344 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01024345 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01024346 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01024347 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01024348 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01024349 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01024350 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01024351 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AF011790 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AF130881 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Reference Sequences
| RefSeq Acc Id: | ENSRNOT00000040306 ⟹ ENSRNOP00000041223 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | ENSRNOT00000049582 ⟹ ENSRNOP00000040240 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_017592338 ⟹ XP_017447827 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| Sequence: |
GGAGGAGAAAGAGCAGCGGCAGAGCGGCAGTCAGCGCACGCCGCTGCTTAGGGAAACAGAAGCGhide sequence |
| RefSeq Acc Id: | XM_017601129 ⟹ XP_017456618 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| Sequence: |
GGAGGAGAAAGAGCAGCGGCAGAGCGGCAGTCAGCGCACGCCGCTGCTTAGGGAAACAGAAGCGhide sequence |
Protein Sequences| Protein RefSeqs | XP_017447827 | (Get FASTA) | NCBI Sequence Viewer |
| XP_017456618 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | AAB65758 | (Get FASTA) | NCBI Sequence Viewer |
| AAD31272 | (Get FASTA) | NCBI Sequence Viewer |
Reference Sequences
| RefSeq Acc Id: | XP_017456618 ⟸ XM_017601129 |
| - Peptide Label: | isoform X2 |
| - Sequence: |
MAESGEGGEDEIQFLRTEDEVVLQCIANIHKEQRKFCLAAEGLGNRLCFLEPTSEAKYIPPDLChide sequence |
| RefSeq Acc Id: | XP_017447827 ⟸ XM_017592338 |
| - Peptide Label: | isoform X1 |
| - Sequence: |
MAESGEGGEDEIQFLRTEDEVVLQCIANIHKEQRKFCLAAEGLGNRLCFLEPTSEAKYIPPDLChide sequence |
| RefSeq Acc Id: | ENSRNOP00000040240 ⟸ ENSRNOT00000049582 |
| RefSeq Acc Id: | ENSRNOP00000041223 ⟸ ENSRNOT00000040306 |
Protein Domains
B30.2/SPRY EF-hand Ion_trans MIR
TranscriptomeStrain Variation
Strain Sequence Variants (Rnor 6.0)
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Additional Information
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:68952 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000006645 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000040240 | UniProtKB/TrEMBL |
| ENSRNOP00000041223 | ENTREZGENE, UniProtKB/TrEMBL | |
| Ensembl Transcript | ENSRNOT00000040306 | ENTREZGENE, UniProtKB/TrEMBL |
| ENSRNOT00000049582 | UniProtKB/TrEMBL | |
| Gene3D-CATH | 2.60.120.920 | UniProtKB/TrEMBL |
| InterPro | ARM-type_fold | UniProtKB/TrEMBL |
| B30.2/SPRY | UniProtKB/TrEMBL | |
| B30.2/SPRY_sf | UniProtKB/TrEMBL | |
| ConA-like_dom | UniProtKB/TrEMBL | |
| EF-hand-like_dom | UniProtKB/TrEMBL | |
| EF_hand_Ca-bd | UniProtKB/TrEMBL | |
| Ins145_P3_rcpt | UniProtKB/TrEMBL | |
| Ion_trans_dom | UniProtKB/TrEMBL | |
| IP3R_RIH_dom | UniProtKB/TrEMBL | |
| MIR_dom_sf | UniProtKB/TrEMBL | |
| MIR_motif | UniProtKB/TrEMBL | |
| RIH_assoc-dom | UniProtKB/TrEMBL | |
| RIH_dom | UniProtKB/TrEMBL | |
| Ryan_recept | UniProtKB/TrEMBL | |
| Ryanodine_rcpt | UniProtKB/TrEMBL | |
| Ryanrecept_TM4-6 | UniProtKB/TrEMBL | |
| RyR1 | UniProtKB/TrEMBL | |
| SPRY1_RyR | UniProtKB/TrEMBL | |
| SPRY2_RyR | UniProtKB/TrEMBL | |
| SPRY3_RyR | UniProtKB/TrEMBL | |
| SPRY_dom | UniProtKB/TrEMBL | |
| NCBI Gene | 170546 | ENTREZGENE |
| PANTHER | PTHR13715:SF15 | UniProtKB/TrEMBL |
| Pfam | Ins145_P3_rec | UniProtKB/TrEMBL |
| Ion_trans | UniProtKB/TrEMBL | |
| MIR | UniProtKB/TrEMBL | |
| RIH_assoc | UniProtKB/TrEMBL | |
| RR_TM4-6 | UniProtKB/TrEMBL | |
| RYDR_ITPR | UniProtKB/TrEMBL | |
| RyR | UniProtKB/TrEMBL | |
| SPRY | UniProtKB/TrEMBL | |
| PhenoGen | Ryr3 | PhenoGen |
| PRINTS | RYANODINER | UniProtKB/TrEMBL |
| PROSITE | B302_SPRY | UniProtKB/TrEMBL |
| EF_HAND_2 | UniProtKB/TrEMBL | |
| MIR | UniProtKB/TrEMBL | |
| SMART | MIR | UniProtKB/TrEMBL |
| SPRY | UniProtKB/TrEMBL | |
| Superfamily-SCOP | SSF100909 | UniProtKB/TrEMBL |
| SSF47473 | UniProtKB/TrEMBL | |
| SSF48371 | UniProtKB/TrEMBL | |
| SSF49899 | UniProtKB/TrEMBL | |
| SSF82109 | UniProtKB/TrEMBL | |
| UniGene | Rn.229451 | ENTREZGENE |
| UniProt | F1LPJ2_RAT | UniProtKB/TrEMBL |
| F1M7A1_RAT | UniProtKB/TrEMBL | |
| O35209_RAT | UniProtKB/TrEMBL | |
| Q9R273_RAT | UniProtKB/TrEMBL |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2002-06-10 | Ryr3 | ryanodine receptor 3 | Symbol and Name status set to approved | 70586 | APPROVED |
RGD Curation Notes| Note Type | Note | Reference |
|---|---|---|
| gene_process | responsible for the increase of Ca++ release during caffeine- and neuromediator-induced global Ca++ response | 67931 |
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| More on Ryr3 | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 68952 |
| Created: | 2001-11-06 |
| Species: | Rattus norvegicus |
| Last Modified: | 2020-08-20 |
| Status: | ACTIVE |
