Ryr3 (ryanodine receptor 3) - Rat Genome Database

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Gene: Ryr3 (ryanodine receptor 3) Rattus norvegicus
Analyze
Symbol: Ryr3
Name: ryanodine receptor 3
RGD ID: 68952
Description: Enables calcium-induced calcium release activity and ryanodine-sensitive calcium-release channel activity. Involved in negative regulation of cytosolic calcium ion concentration. Located in endoplasmic reticulum and perinuclear region of cytoplasm. Orthologous to human RYR3 (ryanodine receptor 3); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; Alzheimer's disease pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acrylamide.
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2399,431,755 - 99,979,125 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl399,432,505 - 99,704,961 (-)Ensembl
Rnor_6.03104,117,307 - 104,665,151 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3104,118,063 - 104,504,204 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03110,710,040 - 111,249,930 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4398,476,626 - 98,872,629 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1398,375,910 - 98,382,386 (-)NCBI
Celera398,415,656 - 98,961,847 (-)NCBICelera
Cytogenetic Map3q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Ischemia enhances activation by Ca2+ and redox modification of ryanodine receptor channels from rat brain cortex. Bull R, etal., J Neurosci. 2008 Sep 17;28(38):9463-72.
2. Identification of functionally segregated sarcoplasmic reticulum calcium stores in pulmonary arterial smooth muscle. Clark JH, etal., J Biol Chem. 2010 Apr 30;285(18):13542-9. doi: 10.1074/jbc.M110.101485. Epub 2010 Feb 21.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Ryanodine receptors: structure, expression, molecular details, and function in calcium release. Lanner JT, etal., Cold Spring Harb Perspect Biol. 2010 Nov;2(11):a003996. doi: 10.1101/cshperspect.a003996. Epub 2010 Oct 20.
6. Contribution of ryanodine receptor subtype 3 to ca2+ responses in Ca2+-overloaded cultured rat portal vein myocytes. Mironneau J, etal., J Biol Chem 2001 Apr 6;276(14):11257-64.
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9384575   PMID:9395096   PMID:10444070   PMID:14592808   PMID:15795312   PMID:16645194   PMID:17360812   PMID:19116207   PMID:23943510  


Genomics

Comparative Map Data
Ryr3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2399,431,755 - 99,979,125 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl399,432,505 - 99,704,961 (-)Ensembl
Rnor_6.03104,117,307 - 104,665,151 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3104,118,063 - 104,504,204 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03110,710,040 - 111,249,930 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4398,476,626 - 98,872,629 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1398,375,910 - 98,382,386 (-)NCBI
Celera398,415,656 - 98,961,847 (-)NCBICelera
Cytogenetic Map3q35NCBI
RYR3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381533,310,967 - 33,866,102 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1533,310,962 - 33,866,121 (+)EnsemblGRCh38hg38GRCh38
GRCh371533,603,168 - 34,158,303 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361531,390,469 - 31,945,595 (+)NCBINCBI36hg18NCBI36
Build 341531,390,468 - 31,945,594NCBI
Celera1510,404,754 - 10,960,825 (+)NCBI
Cytogenetic Map15q13.3-q14NCBI
HuRef1510,464,756 - 11,021,191 (+)NCBIHuRef
CHM1_11533,721,203 - 34,276,301 (+)NCBICHM1_1
T2T-CHM13v2.01531,107,439 - 31,663,747 (+)NCBI
Ryr3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392112,461,699 - 113,047,755 (-)NCBIGRCm39mm39
GRCm39 Ensembl2112,461,700 - 113,047,441 (-)Ensembl
GRCm382112,631,354 - 113,217,405 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2112,631,355 - 113,217,096 (-)EnsemblGRCm38mm10GRCm38
MGSCv372112,471,537 - 112,870,488 (-)NCBIGRCm37mm9NCBIm37
MGSCv362112,432,219 - 112,831,170 (-)NCBImm8
Celera2113,779,152 - 114,176,095 (-)NCBICelera
Cytogenetic Map2E3- E4NCBI
Ryr3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955416713,373 - 1,259,885 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955416712,506 - 1,260,111 (-)NCBIChiLan1.0ChiLan1.0
RYR3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11530,652,244 - 31,215,359 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1530,817,428 - 31,214,494 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01511,816,430 - 12,379,101 (+)NCBIMhudiblu_PPA_v0panPan3
RYR3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1301,179,575 - 1,533,352 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl301,180,359 - 1,533,619 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha301,223,971 - 1,742,310 (-)NCBI
ROS_Cfam_1.0301,278,037 - 1,798,290 (-)NCBI
ROS_Cfam_1.0 Ensembl301,278,037 - 1,798,542 (-)Ensembl
UMICH_Zoey_3.1301,224,326 - 1,741,522 (-)NCBI
UNSW_CanFamBas_1.0301,323,490 - 1,840,773 (-)NCBI
UU_Cfam_GSD_1.0301,451,015 - 1,969,019 (-)NCBI
Ryr3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864079,716,961 - 80,219,351 (-)NCBI
SpeTri2.0NW_0049366732,078,095 - 2,434,872 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RYR3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl780,640,245 - 81,208,334 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1780,640,030 - 81,208,576 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Pig Cytomap7q22-q23NCBI
Ryr3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624804467,295 - 1,030,212 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_004624804467,207 - 1,030,873 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
D3Rat73  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2399,783,911 - 99,784,115 (+)MAPPERmRatBN7.2
Rnor_6.03104,470,998 - 104,471,201NCBIRnor6.0
Rnor_5.03111,056,716 - 111,056,919UniSTSRnor5.0
RGSC_v3.4398,838,741 - 98,838,945RGDRGSC3.4
RGSC_v3.4398,838,742 - 98,838,945UniSTSRGSC3.4
RGSC_v3.1398,735,170 - 98,735,373RGD
Celera398,766,428 - 98,766,631UniSTS
RH 3.4 Map3782.3RGD
RH 3.4 Map3782.3UniSTS
RH 2.0 Map3535.2RGD
FHH x ACI Map357.2899RGD
Cytogenetic Map3q34UniSTS
D3Rat287  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2399,836,810 - 99,837,028 (+)MAPPERmRatBN7.2
Rnor_6.03104,523,357 - 104,523,574NCBIRnor6.0
Rnor_5.03111,109,019 - 111,109,236UniSTSRnor5.0
RGSC_v3.4398,891,743 - 98,891,961RGDRGSC3.4
RGSC_v3.4398,891,744 - 98,891,961UniSTSRGSC3.4
RGSC_v3.1398,788,171 - 98,788,389RGD
Celera398,819,371 - 98,819,588UniSTS
FHH x ACI Map356.16RGD
FHH x ACI Map356.16UniSTS
Cytogenetic Map3q34UniSTS
D3Got51  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2399,678,306 - 99,678,454 (+)MAPPERmRatBN7.2
Rnor_6.03104,367,228 - 104,367,377NCBIRnor6.0
Rnor_5.03110,953,330 - 110,953,479UniSTSRnor5.0
RGSC_v3.4398,730,778 - 98,730,928RGDRGSC3.4
RGSC_v3.4398,730,779 - 98,730,928UniSTSRGSC3.4
RGSC_v3.1398,627,207 - 98,627,356RGD
Celera398,661,749 - 98,661,898UniSTS
RH 3.4 Map3865.3UniSTS
RH 3.4 Map3865.3RGD
RH 2.0 Map3540.2RGD
Cytogenetic Map3q34UniSTS
RH144535  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2399,950,537 - 99,950,775 (+)MAPPERmRatBN7.2
Rnor_6.03104,637,484 - 104,637,721NCBIRnor6.0
Rnor_5.03111,222,292 - 111,222,529UniSTSRnor5.0
RGSC_v3.4399,007,632 - 99,007,869UniSTSRGSC3.4
Celera398,933,602 - 98,933,839UniSTS
RH 3.4 Map3784.0UniSTS
Cytogenetic Map3q34UniSTS
D38218  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2399,432,222 - 99,432,376 (+)MAPPERmRatBN7.2
Rnor_6.03104,117,781 - 104,117,934NCBIRnor6.0
Rnor_5.03110,710,508 - 110,710,661UniSTSRnor5.0
RGSC_v3.4398,476,344 - 98,476,497UniSTSRGSC3.4
Celera398,416,130 - 98,416,283UniSTS
Cytogenetic Map3q34UniSTS
BE101798  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2399,690,981 - 99,691,139 (+)MAPPERmRatBN7.2
Rnor_6.03104,378,025 - 104,378,182NCBIRnor6.0
Rnor_5.03110,964,274 - 110,964,431UniSTSRnor5.0
RGSC_v3.4398,746,237 - 98,746,394UniSTSRGSC3.4
Celera398,673,204 - 98,673,361UniSTS
RH 3.4 Map3757.9UniSTS
Cytogenetic Map3q34UniSTS
AI072496  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2399,431,814 - 99,432,002 (+)MAPPERmRatBN7.2
Rnor_6.03104,117,373 - 104,117,560NCBIRnor6.0
Rnor_5.03110,710,100 - 110,710,287UniSTSRnor5.0
RGSC_v3.4398,475,936 - 98,476,123UniSTSRGSC3.4
Celera398,415,722 - 98,415,909UniSTS
RH 3.4 Map3845.0UniSTS
Cytogenetic Map3q34UniSTS
AW526786  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2399,771,818 - 99,771,983 (+)MAPPERmRatBN7.2
Rnor_6.03104,458,905 - 104,459,069NCBIRnor6.0
Rnor_5.03111,044,623 - 111,044,787UniSTSRnor5.0
RGSC_v3.4398,826,648 - 98,826,812UniSTSRGSC3.4
Celera398,754,384 - 98,754,548UniSTS
RH 3.4 Map3782.9UniSTS
Cytogenetic Map3q34UniSTS
BE120119  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2399,436,299 - 99,436,452 (+)MAPPERmRatBN7.2
Rnor_6.03104,121,856 - 104,122,008NCBIRnor6.0
Rnor_5.03110,714,583 - 110,714,735UniSTSRnor5.0
RGSC_v3.4398,480,419 - 98,480,571UniSTSRGSC3.4
Celera398,420,205 - 98,420,357UniSTS
RH 3.4 Map3758.0UniSTS
Cytogenetic Map3q34UniSTS
RH138135  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2399,559,946 - 99,560,097 (+)MAPPERmRatBN7.2
Rnor_6.03104,250,226 - 104,250,376NCBIRnor6.0
Rnor_5.03110,836,878 - 110,837,028UniSTSRnor5.0
RGSC_v3.4398,605,146 - 98,605,296UniSTSRGSC3.4
Celera398,543,711 - 98,543,861UniSTS
RH 3.4 Map3869.9UniSTS
Cytogenetic Map3q34UniSTS
Ryr3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2399,440,333 - 99,441,268 (+)MAPPERmRatBN7.2
Rnor_6.03104,125,890 - 104,126,824NCBIRnor6.0
Rnor_5.03110,718,617 - 110,719,551UniSTSRnor5.0
RGSC_v3.4398,484,453 - 98,485,387UniSTSRGSC3.4
Celera398,424,239 - 98,425,173UniSTS
Cytogenetic Map3q34UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)341874578104104347Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
1581568Rf53Renal function QTL 53total urine protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)364655305115665732Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)364655305115665732Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)373376539118376539Rat
1581546Pur13Proteinuria QTL 132.930.0335total urine protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
2302273Gluco35Glucose level QTL 355.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)380800231114297550Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)389772419134772419Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)391797474136797474Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)395735366140735366Rat
1582252Sual1Serum uric acid level QTL 13.40.0123blood uric acid amount (VT:0010302)blood uric acid level (CMO:0000501)396127817102200699Rat
1582219Bw63Body weight QTL 633.80.001body mass (VT:0001259)body weight (CMO:0000012)396127817115665732Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:124
Count of miRNA genes:65
Interacting mature miRNAs:72
Transcripts:ENSRNOT00000027865, ENSRNOT00000040306, ENSRNOT00000049582
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 24 4 7
Low 3 41 17 1 19 1 8 9 50 20 32 4 8
Below cutoff 2 17 17 17 2 11 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000040306   ⟹   ENSRNOP00000041223
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl399,432,505 - 99,704,961 (-)Ensembl
Rnor_6.0 Ensembl3104,118,063 - 104,502,471 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000049582   ⟹   ENSRNOP00000040240
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl3104,118,063 - 104,504,204 (-)Ensembl
RefSeq Acc Id: XM_039106806   ⟹   XP_038962734
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2399,431,755 - 99,979,125 (-)NCBI
Protein Sequences
Protein RefSeqs XP_038962734 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB65758 (Get FASTA)   NCBI Sequence Viewer  
  AAD31272 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: ENSRNOP00000040240   ⟸   ENSRNOT00000049582
RefSeq Acc Id: ENSRNOP00000041223   ⟸   ENSRNOT00000040306
RefSeq Acc Id: XP_038962734   ⟸   XM_039106806
Protein Domains
Ion_trans

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:68952 AgrOrtholog
BioCyc Gene G2FUF-48379 BioCyc
Ensembl Genes ENSRNOG00000006645 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000040306 ENTREZGENE
InterPro Ion_trans_dom UniProtKB/TrEMBL
NCBI Gene 170546 ENTREZGENE
Pfam Ion_trans UniProtKB/TrEMBL
PhenoGen Ryr3 PhenoGen
UniProt O35209_RAT UniProtKB/TrEMBL
  Q9R273_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Ryr3  ryanodine receptor 3      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_process responsible for the increase of Ca++ release during caffeine- and neuromediator-induced global Ca++ response 67931