Myo3b (myosin IIIB) - Rat Genome Database

Name: Myo3b
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Myo3b (myosin IIIB) Rattus norvegicus

Analyze

Symbol:

Myo3b

Name:

myosin IIIB

RGD ID:

1560313

Description:

Predicted to have microfilament motor activity and protein serine/threonine kinase activity. Predicted to be involved in several processes, including inner ear morphogenesis; positive regulation of filopodium assembly; and protein phosphorylation. Predicted to localize to several cellular components, including filopodium tip; photoreceptor inner segment; and stereocilium tip. Orthologous to human MYO3B (myosin IIIB); INTERACTS WITH acrylamide; bisphenol A; C60 fullerene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

LOC366069; myosin-IIIb; RGD1560313; similar to myosin IIIB

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MYO3B (myosin IIIB)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Myo3b (myosin IIIB)	HGNC	Treefam, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Myo3b (myosin IIIB)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MYO3B (myosin IIIB)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MYO3B (myosin IIIB)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Myo3b (myosin IIIB)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MYO3B (myosin IIIB)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	MYO3B (myosin IIIB)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Myo3b (myosin IIIB)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	MYO3A (myosin IIIA)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	MYO3B (myosin IIIB)	Alliance	DIOPT (HGNC\|TreeFam)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	54,873,704 - 55,226,189 (+)	NCBI
Rnor_6.0 Ensembl	3	56,355,431 - 56,584,547 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	3	56,355,433 - 56,717,740 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	3	62,983,084 - 63,336,893 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	52,249,255 - 52,645,911 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
Celera	3	54,432,675 - 54,783,264 (+)	NCBI		Celera
Cytogenetic Map	3	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,3,7,8-tetrachlorodibenzodioxine (ISO)

acrylamide (EXP)

aflatoxin B1 (ISO)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

avobenzone (ISO)

belinostat (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP)

C60 fullerene (EXP)

carbon nanotube (ISO)

clothianidin (ISO)

dorsomorphin (ISO)

ethyl methanesulfonate (ISO)

folic acid (ISO)

hydroquinone O-beta-D-glucopyranoside (ISO)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

phenylmercury acetate (ISO)

SB 431542 (ISO)

trichostatin A (ISO)

trimellitic anhydride (ISO)

valproic acid (ISO)

vanadyl sulfate (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

auditory receptor cell stereocilium organization (ISO)

cochlea morphogenesis (ISO)

peptidyl-serine phosphorylation (ISO)

peptidyl-threonine phosphorylation (ISO)

positive regulation of filopodium assembly (ISO)

protein autophosphorylation (ISO)

regulation of actin filament length (ISO)

sensory perception of sound (ISO)

visual perception (IEA)

Cellular Component

filopodium tip (ISO)

myosin complex (IEA)

photoreceptor inner segment (ISO)

photoreceptor outer segment (ISO)

stereocilium tip (ISO)

Molecular Function

actin binding (IEA)

ATP binding (IEA)

microfilament motor activity (ISO)

protein binding (ISO)

protein serine/threonine kinase activity (ISO)

References

References - curated


1.	RGD automated data pipeline
2.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:19332056	PMID:21895655	PMID:22264607	PMID:26754646

Genomics

Comparative Map Data

Myo3b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	54,873,704 - 55,226,189 (+)	NCBI
Rnor_6.0 Ensembl	3	56,355,431 - 56,584,547 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	3	56,355,433 - 56,717,740 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	3	62,983,084 - 63,336,893 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	52,249,255 - 52,645,911 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
Celera	3	54,432,675 - 54,783,264 (+)	NCBI		Celera
Cytogenetic Map	3	q22	NCBI

MYO3B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	2	170,178,145 - 170,655,171 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	2	170,178,147 - 170,655,167 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	2	171,034,657 - 171,511,677 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	170,742,901 - 171,219,237 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	2	170,860,161 - 171,336,490	NCBI
Celera	2	164,651,295 - 165,128,332 (+)	NCBI
Cytogenetic Map	2	q31.1	NCBI
HuRef	2	162,921,994 - 163,399,266 (+)	NCBI		HuRef
CHM1_1	2	171,041,013 - 171,517,916 (+)	NCBI		CHM1_1

Myo3b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	69,869,470 - 70,259,539 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	2	69,869,470 - 70,259,542 (+)	Ensembl
GRCm38	2	70,039,126 - 70,429,195 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	70,039,126 - 70,429,198 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	69,877,183 - 70,267,252 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	2	70,090,181 - 70,229,066 (+)	NCBI			mm8
Celera	2	71,707,289 - 72,093,949 (+)	NCBI		Celera
Cytogenetic Map	2	C2	NCBI

Myo3b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955449	4,129,823 - 4,546,296 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955449	4,128,816 - 4,546,651 (-)	NCBI	ChiLan1.0	ChiLan1.0

MYO3B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	2B	174,918,336 - 175,400,225 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	174,975,796 - 175,398,203 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	2B	57,458,046 - 57,940,039 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

MYO3B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	36	14,803,514 - 15,209,820 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	36	14,804,662 - 15,229,597 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Myo3b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936509	615,958 - 1,074,742 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MYO3B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	76,401,963 - 76,855,432 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	76,432,429 - 76,855,443 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	85,633,926 - 85,907,792 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MYO3B
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	55,710,658 - 56,184,514 (+)	NCBI

Myo3b
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624787	7,723,491 - 7,915,619 (+)	NCBI

Position Markers

D3Rat119

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	3	56,715,183 - 56,715,367	NCBI	Rnor6.0
Rnor_5.0	3	63,334,336 - 63,334,520	UniSTS	Rnor5.0
RGSC_v3.4	3	52,643,353 - 52,643,535	RGD	RGSC3.4
RGSC_v3.4	3	52,643,354 - 52,643,538	UniSTS	RGSC3.4
RGSC_v3.1	3	52,539,725 - 52,539,907	RGD
Celera	3	54,780,707 - 54,780,891	UniSTS
RH 3.4 Map	4	528.24	UniSTS
RH 3.4 Map	4	528.24	RGD
RH 2.0 Map	3	439.0	RGD
SHRSP x BN Map	3	37.2498	RGD
FHH x ACI Map	3	40.5599	RGD
Cytogenetic Map	3	q21	UniSTS

D3Uwm2

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	3	56,532,014 - 56,532,299	NCBI	Rnor6.0
Rnor_5.0	3	63,158,212 - 63,158,497	UniSTS	Rnor5.0
RGSC_v3.4	3	52,441,500 - 52,441,786	RGD	RGSC3.4
RGSC_v3.4	3	52,441,501 - 52,441,786	UniSTS	RGSC3.4
RGSC_v3.1	3	52,337,872 - 52,338,158	RGD
Celera	3	54,608,379 - 54,608,664	UniSTS
Cytogenetic Map	3	q21	UniSTS

D3Chm65

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	3	56,484,063 - 56,484,263	NCBI	Rnor6.0
Rnor_5.0	3	63,110,261 - 63,110,461	UniSTS	Rnor5.0
RGSC_v3.4	3	52,393,550 - 52,393,751	RGD	RGSC3.4
RGSC_v3.4	3	52,393,551 - 52,393,751	UniSTS	RGSC3.4
Celera	3	54,560,422 - 54,560,622	UniSTS
Cytogenetic Map	3	q21	UniSTS

D3Got209

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	3	56,388,668 - 56,388,890	NCBI	Rnor6.0
Rnor_5.0	3	63,016,319 - 63,016,541	UniSTS	Rnor5.0
RGSC_v3.4	3	52,295,759 - 52,295,981	UniSTS	RGSC3.4
Celera	3	54,466,159 - 54,466,381	UniSTS
Cytogenetic Map	3	q21	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2290452	Scl56	Serum cholesterol level QTL 56	2.26		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	3	1	95176874	Rat
1358905	Hrtrt17	Heart rate QTL 17	5.9	0.000014	heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	10094081	93415837	Rat
2298542	Neuinf11	Neuroinflammation QTL 11	3.9		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	3	10119318	79772001	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	10639528	127023997	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	10639528	127023997	Rat
631676	Cm8	Cardiac mass QTL 8	7.03	0.0001	aorta mass (VT:0002845)	aorta weight (CMO:0000076)	3	18023664	63023664	Rat
10450794	Scl69	Serum cholesterol level QTL 69	6.3	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	21223803	66223803	Rat
10450804	Scl70	Serum cholesterol level QTL 70	4.7	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	21223803	66223803	Rat
631685	Bp118	Blood pressure QTL 118	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	24655225	69655225	Rat
2302055	Pia30	Pristane induced arthritis QTL 30	3.5	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)	3	29321714	74321714	Rat
9590286	Uminl1	Urine mineral level QTL 1	3.5	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	3	29682732	74682732	Rat
9590136	Scort3	Serum corticosterone level QTL 3	23.37	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	29682732	74682732	Rat
8552950	Pigfal12	Plasma insulin-like growth factor 1 level QTL 12	7.3		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	3	29682732	74682732	Rat
8694196	Abfw2	Abdominal fat weight QTL 2	16.58	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	3	29682732	74682732	Rat
8694386	Bw159	Body weight QTL 159	4.52	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	3	29682732	74682732	Rat
1354590	Despr11	Despair related QTL 11		0.000031	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	3	29908255	74908255	Rat
2303593	Gluco46	Glucose level QTL 46	3		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	29908255	74908255	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	30114912	123700444	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	30846101	172879276	Rat
2301400	Cm68	Cardiac mass QTL 68		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	3	31103589	72989078	Rat
11565451	Bw177	Body weight QTL 177		0.002	body mass (VT:0001259)	body weight (CMO:0000012)	3	31103589	72989078	Rat
11565452	Kidm57	Kidney mass QTL 57		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	31103589	72989078	Rat
12879866	Cm94	Cardiac mass QTL 94		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	31103589	72989078	Rat
12879867	Cm95	Cardiac mass QTL 95		0.047	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	3	31103589	72989078	Rat
12879868	Am6	Aortic mass QTL 6		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	3	31103589	72989078	Rat
61356	Bp37	Blood pressure QTL 37	3		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	3	32130997	77130997	Rat
631647	Bp122	Blood pressure QTL 122	6.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	32130997	77130997	Rat
1300169	Bp177	Blood pressure QTL 177	2.96		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	3	33477354	62922975	Rat
1354589	Bw31	Body weight QTL 31	3.3		body mass (VT:0001259)	body weight (CMO:0000012)	3	33477354	81136227	Rat
1354604	Bw36	Body weight QTL 36	2.9		body mass (VT:0001259)	body weight (CMO:0000012)	3	33477354	108914061	Rat
61419	Cia11	Collagen induced arthritis QTL 11	5.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	3	34394121	103141944	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	39248391	140271184	Rat
738019	Anxrr10	Anxiety related response QTL 10	3.9		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	3	40422921	85422921	Rat
2302276	Bw82	Body weight QTL 82	4.32		body mass (VT:0001259)	body weight (CMO:0000012)	3	40523593	64880586	Rat
1331777	Bw24	Body weight QTL 24	3.503		body mass (VT:0001259)	body weight (CMO:0000012)	3	40523593	92654473	Rat
1331795	Rf30	Renal function QTL 30	3.708		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	3	40523593	92654473	Rat
1354597	Kidm13	Kidney mass QTL 13	2.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	3	43295930	108914061	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	43295930	163640485	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	43295930	163640485	Rat
1300178	Hrtrt4	Heart rate QTL 4	3.74		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	45406058	94467785	Rat
1581503	Cm58	Cardiac mass QTL 58	2.7	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	45406058	127023997	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	45406058	177699992	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	48561928	155263151	Rat
1358186	Ept2	Estrogen-induced pituitary tumorigenesis QTL 2	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	48562146	115249962	Rat
2292613	Ept16	Estrogen-induced pituitary tumorigenesis QTL 16	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	48562146	115249962	Rat
631665	Bw8	Body weight QTL 8	5.5		body mass (VT:0001259)	body weight (CMO:0000012)	3	51821836	124513579	Rat
724523	Tsu1	Thymus enlargement suppressive QTL 1	3.84		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	3	51822008	120917851	Rat
1582249	Bw77	Body weight QTL 77	3.2	0.0025	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	3	54630948	66711785	Rat
1582218	Bw74	Body weight QTL 74	3.9	0.0021	body mass (VT:0001259)	body weight (CMO:0000012)	3	54630948	119830094	Rat
1582238	Bw68	Body weight QTL 68	3.2	0.0064	body mass (VT:0001259)	body weight (CMO:0000012)	3	54630948	119830094	Rat
1582239	Epfw1	Epididymal fat weight QTL 1	4.5	0.0006	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	3	54630948	119830094	Rat
61377	Edpm3	Estrogen-dependent pituitary mass QTL 3	7.05	0.038	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	54631046	93415673	Rat
731180	Bp152	Blood pressure QTL 152		0.03	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	55245276	95176874	Rat
731180	Bp152	Blood pressure QTL 152		0.03	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	3	55245276	95176874	Rat
731180	Bp152	Blood pressure QTL 152		0.03	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	55245276	95176874	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	120
Count of miRNA genes:	95
Interacting mature miRNAs:	103
Transcripts:	ENSRNOT00000037188
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	circulatory system	endocrine system	exocrine system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium
Low	13				5	5	9	35	26	11	5
Below cutoff	30	1	1	1	3	4	61		14		3

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001191901	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC118797	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000115	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000037188 ⟹ ENSRNOP00000032998

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	3	56,355,431 - 56,584,547 (+)	Ensembl

RefSeq Acc Id:

NM_001191901 ⟹ NP_001178830

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	54,873,704 - 55,226,189 (+)	NCBI
Rnor_6.0	3	56,355,433 - 56,717,740 (+)	NCBI
Rnor_5.0	3	62,983,084 - 63,336,893 (+)	NCBI
Celera	3	54,432,675 - 54,783,264 (+)	NCBI

Sequence:

show sequence

ATGACGAAACACCTGTATGGATTATTTCACTATAACTCCATGATGCTTAGACTGGAATCCCTCC
CAGACCCCATGGACACCTGGGAGATTAGAGAGACCATTGGCAAAGGCACTTACGGCAAGGTCTA
CAAGGTAGCCAACAGAAGAGACGGGAGTCTGGCTGCCGTGAAGATTCTGGACTCCGTCAATGAC
GTGGATGAGGAGGTGGAGGCTGAATACAACATTCTGCAGTTTCTCCCCAGCCATCCCAATGTTG
TAAAGTTTTATGGGATGTTTTACAAAGCTGATCGCTGTGTGGGAGGGCAGCTGTGGCTGGTTCT
GGAGCTGTGTAATGGGGGCTCCGTCACTGAGCTTGTCAAGGGCCTCCTGAGGTGTGGTAAGCGG
CTGGATGAAGCTCTGATCTCCTACATTCTGTATGGATCCCTCTTGGGCCTTCAGCACTTGCACC
ATCACCGAATCATCCACCGAGATGTGAAGGGGAATAACATTCTTCTGACGACAGAAGGAGGAGT
TAAGCTCGTTGACTTTGGTGTCTCTGCTCAACTTACAAGCACACGGCTACGGAGAAACACATCG
GTTGGGACCCCATTCTGGATGGCTCCAGAGGTCATTGCTTGTGAGCAGCAGTATGACTCGTCCT
ATGACGCTCGCTGTGACGTCTGGTCCTTGGGCATCACAGCCATCGAGCTGGGCGATGGAGACCC
TCCCCTCTTTGAAATGCATCCTGTGAAGATGCTCTTTAAGATCCCAAGAAACCCTCCACCCACT
TTGCTGCACCCGGACAACTGGTGTGAGGAGTTTAACCACTTCATTTCACAGTGTCTTATTAAAG
ATTTTGAAAAGCGGCCTTCGGTCACCCATCTCCTGGATCACCCATTCATTAAAGGAACTCAAGG
CAAGGTTTTGTTTCTTCAAAAACAGCTGGCCAAGGTGCTCTGGGACCAGAAGCATCAAAACCCT
GTTGCTAAAACCAGGCATGAAAGGATGCATACTGGAAGACCCCATCATGTGGAGGATGCTGGTA
AATGCTGCCTTGAGGATGACTTGGTCAATCTTGAGGTCCTGGACGAGGATACGATTATCTACTG
GCTGCAGAAGCGATATGCAGATGCGCTGATCTACACCTATGTGGGAGATATTCTGATTGCCTTA
AACCCCTTCCAGAATCTAAGCATATACTCTCCACAGTTTTCCAGGCTTTACCACGGGGTGAAGC
GTTCCTCAAATCCCCCCCACATATTCGCATCAGCAGATAATGCTTACCAGTGTTTAGTTACCTT
CAGCAAAGACCAGTGCATTGTCATCAGTGGGGAAAGCGGATCCGGGAAGACGGAAAACGCCCAT
CTGATCGTCCAGCACCTCACTTTCTTAGGAAAGGCCAACAATCAGACCTTACGCCAGAAGATTC
TCCAAGTAAACTCCCTGGTGGAAGCCTTTGGGAACGCCCGCACAGCCATCAACGATAACTCCAG
CCGCTTCGGGAAATATCTGGAAATGATGTTCACACCAACGGGAGCTGTCATGGGGGCGAGAATC
TCCGAGTATCTCCTTGAAAAATCCAGAGTTATACAGCAGGCAGCGGGAGAGAAAAATTTTCACA
TATTTTATTATATTTATGCTGGTCTTTATCACCAAAAGAAACTTGCTGAATTCAGACTTCCTGA
GGAAAAGCCTCCTAGATATATAGCTGCTGAGACGGAAAGAGTCACGCAGGACATCACGTCCAAA
GAGTCTTACCGGAGACAGTTTGACGTGATTCAGCATTGCTTCAGGATTATCGGATTCACTGACA
AGGAGGTACACTCCGTGTACAGAATTCTGGCTGGGATTTTGAACATCGGCAACATTGAGTTTGC
AGCTATTTCCTCTCAACACCAGACTGATAAAAGTGAGGTTCCCAATCCCGAAGCTTTGGAAAAC
GCTGCCTCCGTGCTCTGCATCAACTCTGAAGAGCTTCAGGAGGCCCTCACGTCCCACTGTGTGG
TCACAAGAGGCGAGACCATTGTCCGAGCCAACACAGTGGACAGGGCTGAAGATGTCAGGGACGC
CATGTCTAAGGCCCTCTATGGAAGGCTGTTCAGCTGGATTGTGAATCGAATCAACACACTCCTG
CAGCCAGATAAAAACATATGTAGTGCAGAGGACAGGATGAATGTGGGCATCCTGGACATTTTTG
GCTTTGAGGATTTCCAGAGGAATTCCTTTGAACAGCTCTGCATAAATATCGCCAACGAACAGGT
CCAGTTCTACTTCAATCAGCACGTGTTCGCTCTTGAGCAGATGGAGTATAAAAAGGAAGGCGTC
GATGCTGTCCTCGTGCAGTACGAAGACAATCGCCCACTCCTGGACATGTTCCTGCAAAAACCCT
TGGGCCTTCTAGCACTTTTGGATGAGGAAAGTCGATTTCCCCAAGGAACAGACCAGACTTTGGT
TGATAAATTTGAAGACAACCTACGATGCAAGTTCTTCTGGAGGCCCAAAGGAGTGGAACTCTCT
TTCGGCATTCAGCACTATGCTGGACCGGTGCTGTACGATGCTTCTGGGGTTCTTGAGAAAAACA
GAGACACCCTCCCTGCTGATGTGGTGGTAGTCCTGAGGACATCTGAGAACAAGCTCCTTCAGCA
ACTGTTCTCAATTCCTTTGACCAAAACAGGTAATTTGGCACAAACGAGAGCTAGGATCACAGCC
TCCTCGAGATCTTTGCCTCCACATTTCAGTGCTGGGAGGGCTAAGGTAGACACCCTGGAGGTGA
TTCGACATCCAGAAGAAACCACCAACATGAAGAGACAAACCATGGCTTCTTACTTCCGGTATTC
TCTGATGGATCTGCTCTCCAAAATGGTGGTTGGACAGCCCCATTTCGTTCGTTGCATTAAGCCT
AATGACGACCGCAAGGCCCTGCAATTCTCCCAAGACAGAGTCTTGGCCCAGCTTCGCTCCACAG
GGATCCTGGAGACTGTCAGCATCCGCAGGCAGGGCTACTCCCATCGCATCCTTTTCGAAGAGTT
TGTAAGACGGTATTATTACTTGGCATTCCGAGCACATCAAACACCTCCAGCTAACAAAGAGAGC
TGTGTTGCTATCTTGGAAAAGTCCAGATTAGATCACTGGGTCCTGGGAAAAACAAAGGTTTTTC
TCAAATATTACCACATCGAGCAGTTGAATTTGCTTCTTCGGGAAGTTATGGGCCGAGTGGTCAT
GCTACAGGCATATACCAAGGGTTGGCTCGGAGCGAGGAGATACAAGAGAGCCAAAGAGAAGAGA
GAGAAGAGCGCCATAACCATCCAGTCAGCCTGGAGAGGATATGATACTCGGAGGAAATTTAAGC
AAACAAGGCACAGGAGGAACGAGTCTGCAGCTCACACTCAAGCAGAGTGCACCGGCACCTCTGG
AATACGGAACGTGGCAAACGCACTGAGCAGAAAGCATCCACAAACCCAGAGTTCCCCAGCCAGC
AGTGATGTCACCTCGGGACATGCAGATAAGGAAGCCGGGAATGCTGTTGCTGAGCTCTCAGTTG
CTGGAACCGATGGGTCACCATCTCGGGTGTGTCACACTGCCACAGCTCACCACAGACTGAGCCC
CTGCGAAGTCTCTCTCAAACCAGGTTCAGAAGAAGGTCTCTCACAGAAGCAGCGAGCACCTCGC
AGACGGTGTCAGCAGCCCAAAATGTTGAGTAGCCCCGAGGACACCATGTACTATAACCAGCTAA
ACGGAACTCTAGAATATCAAGGGAGCCAGAGGAAGCCAAGAAAACTTGGACAAATCAAAGTGCT
GGATGGGGAAGACCAATATTACAAATGCCTGTCTCCTGGGGCCTGTGCCCCTGAGGAAACCCAC
TCGGCCCACTCTTTCTTCTTCTCCTTGCCCCCCGGAGAAGACTCCTTTGCTCAACACTGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001178830	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL79079	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001178830 ⟸ NM_001191901

- Sequence:

show sequence

MTKHLYGLFHYNSMMLRLESLPDPMDTWEIRETIGKGTYGKVYKVANRRDGSLAAVKILDSVND
VDEEVEAEYNILQFLPSHPNVVKFYGMFYKADRCVGGQLWLVLELCNGGSVTELVKGLLRCGKR
LDEALISYILYGSLLGLQHLHHHRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTS
VGTPFWMAPEVIACEQQYDSSYDARCDVWSLGITAIELGDGDPPLFEMHPVKMLFKIPRNPPPT
LLHPDNWCEEFNHFISQCLIKDFEKRPSVTHLLDHPFIKGTQGKVLFLQKQLAKVLWDQKHQNP
VAKTRHERMHTGRPHHVEDAGKCCLEDDLVNLEVLDEDTIIYWLQKRYADALIYTYVGDILIAL
NPFQNLSIYSPQFSRLYHGVKRSSNPPHIFASADNAYQCLVTFSKDQCIVISGESGSGKTENAH
LIVQHLTFLGKANNQTLRQKILQVNSLVEAFGNARTAINDNSSRFGKYLEMMFTPTGAVMGARI
SEYLLEKSRVIQQAAGEKNFHIFYYIYAGLYHQKKLAEFRLPEEKPPRYIAAETERVTQDITSK
ESYRRQFDVIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEVPNPEALEN
AASVLCINSEELQEALTSHCVVTRGETIVRANTVDRAEDVRDAMSKALYGRLFSWIVNRINTLL
QPDKNICSAEDRMNVGILDIFGFEDFQRNSFEQLCINIANEQVQFYFNQHVFALEQMEYKKEGV
DAVLVQYEDNRPLLDMFLQKPLGLLALLDEESRFPQGTDQTLVDKFEDNLRCKFFWRPKGVELS
FGIQHYAGPVLYDASGVLEKNRDTLPADVVVVLRTSENKLLQQLFSIPLTKTGNLAQTRARITA
SSRSLPPHFSAGRAKVDTLEVIRHPEETTNMKRQTMASYFRYSLMDLLSKMVVGQPHFVRCIKP
NDDRKALQFSQDRVLAQLRSTGILETVSIRRQGYSHRILFEEFVRRYYYLAFRAHQTPPANKES
CVAILEKSRLDHWVLGKTKVFLKYYHIEQLNLLLREVMGRVVMLQAYTKGWLGARRYKRAKEKR
EKSAITIQSAWRGYDTRRKFKQTRHRRNESAAHTQAECTGTSGIRNVANALSRKHPQTQSSPAS
SDVTSGHADKEAGNAVAELSVAGTDGSPSRVCHTATAHHRLSPCEVSLKPGSEEGLSQKQRAPR
RRCQQPKMLSSPEDTMYYNQLNGTLEYQGSQRKPRKLGQIKVLDGEDQYYKCLSPGACAPEETH
SAHSFFFSLPPGEDSFAQH

hide sequence

RefSeq Acc Id:

ENSRNOP00000032998 ⟸ ENSRNOT00000037188

Protein Domains

Myosin motor Protein kinase

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1560313	AgrOrtholog
Ensembl Genes	ENSRNOG00000030022	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000032998	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000037188	ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH	3.40.850.10	UniProtKB/TrEMBL
InterPro	IQ_motif_EF-hand-BS	UniProtKB/TrEMBL
	Kinase-like_dom	UniProtKB/TrEMBL
	Kinesin_motor_dom_sf	UniProtKB/TrEMBL
	Myosin_head_motor_dom	UniProtKB/TrEMBL
	MYSc_Myo3	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
	Prot_kinase_cat_dom	UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/TrEMBL
	Ser/Thr_kinase_AS	UniProtKB/TrEMBL
NCBI Gene	366069	ENTREZGENE
Pfam	Myosin_head	UniProtKB/TrEMBL
	PF00612	UniProtKB/TrEMBL
	Pkinase	UniProtKB/TrEMBL
PhenoGen	Myo3b	PhenoGen
PRINTS	MYOSINHEAVY	UniProtKB/TrEMBL
PROSITE	MYOSIN_MOTOR	UniProtKB/TrEMBL
	PROTEIN_KINASE_ATP	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
	PROTEIN_KINASE_ST	UniProtKB/TrEMBL
	PS50096	UniProtKB/TrEMBL
SMART	MYSc	UniProtKB/TrEMBL
	S_TKc	UniProtKB/TrEMBL
	SM00015	UniProtKB/TrEMBL
Superfamily-SCOP	Kinase_like	UniProtKB/TrEMBL
	SSF52540	UniProtKB/TrEMBL
UniProt	F1LWJ6_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2010-04-23	Myo3b	myosin IIIB	RGD1560313	similar to myosin IIIB	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1560313	similar to myosin IIIB	RGD1560313_predicted	similar to myosin IIIB (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-07	RGD1560313_predicted	similar to myosin IIIB (predicted)	LOC366069	similar to myosin IIIB	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC366069	similar to myosin IIIB			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)