Gene: Chrm4 (cholinergic receptor, muscarinic 4) Rattus norvegicus
Symbol: Chrm4
Name: cholinergic receptor, muscarinic 4
Description: ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity; G-protein coupled acetylcholine receptor activity (ortholog); INVOLVED IN response to organic substance; adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway (ortholog); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphai protein family; G protein mediated signaling pathway via Galphai family; ASSOCIATED WITH Heart Failure; Catatonia (ortholog); Tremor (ortholog); FOUND IN asymmetric synapse; axon terminus; cytoplasm; INTERACTS WITH (+)-pilocarpine; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cholinergic receptor, muscarin 4; M4; muscarinic acetylcholine receptor M4
Homo sapiens (human) : CHRM4 (cholinergic receptor muscarinic 4)  HGNC  Alliance
Mus musculus (house mouse) : Chrm4 (cholinergic receptor, muscarinic 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chrm4 (cholinergic receptor muscarinic 4)
Pan paniscus (bonobo/pygmy chimpanzee) : CHRM4 (cholinergic receptor muscarinic 4)
Canis lupus familiaris (dog) : CHRM4 (cholinergic receptor muscarinic 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chrm4 (cholinergic receptor muscarinic 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0380,833,272 - 80,841,165 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0387,531,619 - 87,539,681 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4376,301,988 - 76,309,729 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1376,203,520 - 76,206,094 (+)NCBI
Celera377,096,073 - 77,103,815 (+)NCBICelera
Cytogenetic Map3q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Chrm4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2344
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-03-20
Status: ACTIVE