CHRM4 (cholinergic receptor muscarinic 4)

Gene: CHRM4 (cholinergic receptor muscarinic 4) Chlorocebus sabaeus

Analyze

Symbol:

CHRM4

Name:

cholinergic receptor muscarinic 4

RGD ID:

18416023

Description:

ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway (ortholog); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphai protein family; G protein mediated signaling pathway via Galphai family; ASSOCIATED WITH Catatonia (ortholog); congenital disorder of glycosylation type IIc (ortholog); congestive heart failure (ortholog); FOUND IN asymmetric synapse (ortholog); axon terminus (ortholog); glutamatergic synapse (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

muscarinic acetylcholine receptor M4

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	18,937,455 - 18,945,390 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	18,942,643 - 18,944,079 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	116,222,834 - 116,230,831 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Catatonia (ISO)

congenital disorder of glycosylation type IIc (ISO)

congestive heart failure (ISO)

Developmental Disabilities (ISO)

genetic disease (ISO)

intellectual disability (ISO)

Tremor (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

acetylcholine receptor signaling pathway (IEA)

adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway (IEA,ISO)

chemical synaptic transmission (IEA)

G protein-coupled receptor signaling pathway (IEA)

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger (IEA)

G protein-coupled serotonin receptor signaling pathway (IEA)

regulation of locomotion (IEA)

Cellular Component

asymmetric synapse (ISO)

axon terminus (ISO)

cell junction (IEA)

dendrite (IEA)

glutamatergic synapse (ISO)

membrane (ISO)

neuronal cell body (ISO)

plasma membrane (IEA)

postsynaptic density membrane (ISO)

postsynaptic membrane (IEA)

presynaptic membrane (ISO)

sarcolemma (ISO)

synapse (IEA)

Molecular Function

G protein-coupled acetylcholine receptor activity (IEA)

G protein-coupled receptor activity (IEA)

G protein-coupled serotonin receptor activity (IEA)

guanyl-nucleotide exchange factor activity (ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphai protein family (ISO)

G protein mediated signaling pathway via Galphai family (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

CHRM4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	18,937,455 - 18,945,390 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	18,942,643 - 18,944,079 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	116,222,834 - 116,230,831 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

CHRM4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	46,383,789 - 46,391,776 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	46,383,789 - 46,391,776 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	46,405,339 - 46,413,326 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	46,363,216 - 46,364,683 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	46,363,215 - 46,364,683	NCBI
Celera	11	46,554,217 - 46,555,684 (-)	NCBI		Celera
Cytogenetic Map	11	p11.2	NCBI
HuRef	11	46,113,598 - 46,115,064 (-)	NCBI		HuRef
CHM1_1	11	46,405,093 - 46,406,560 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	46,539,864 - 46,547,851 (-)	NCBI		T2T-CHM13v2.0

Chrm4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	91,752,531 - 91,760,180 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	91,757,594 - 91,759,033 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	91,922,189 - 91,929,835 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	91,927,249 - 91,928,688 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	91,762,346 - 91,769,986 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	91,728,088 - 91,729,527 (+)	NCBI		MGSCv36	mm8
Celera	2	93,312,590 - 93,320,231 (+)	NCBI		Celera
Cytogenetic Map	2	E1	NCBI
cM Map	2	50.63	NCBI

Chrm4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	98,349,080 - 98,356,821 (+)	NCBI		GRCr8
mRatBN7.2	3	77,893,425 - 77,901,166 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	77,893,425 - 77,901,159 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	81,368,613 - 81,376,348 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	89,967,641 - 89,975,378 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	87,818,870 - 87,826,600 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	80,833,272 - 80,841,165 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	80,833,272 - 80,841,006 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	87,531,619 - 87,539,681 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	76,301,988 - 76,309,729 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	76,203,520 - 76,206,094 (+)	NCBI
Celera	3	77,096,073 - 77,103,815 (+)	NCBI		Celera
Cytogenetic Map	3	q24	NCBI

Chrm4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	1,647,663 - 1,655,363 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955422	1,647,663 - 1,655,363 (+)	NCBI	ChiLan1.0	ChiLan1.0

CHRM4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	48,596,916 - 48,606,737 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	48,603,743 - 48,611,729 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	46,342,384 - 46,350,366 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	46,893,292 - 46,901,074 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	46,894,615 - 46,896,054 (-)	Ensembl	panpan1.1		panPan2

CHRM4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	43,077,115 - 43,084,298 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	43,082,404 - 43,083,840 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	41,805,766 - 41,813,475 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	43,733,324 - 43,740,846 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	43,733,289 - 43,741,042 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	43,218,330 - 43,226,035 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	42,770,212 - 42,777,904 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	43,503,419 - 43,510,935 (+)	NCBI		UU_Cfam_GSD_1.0

Chrm4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	20,567,540 - 20,576,257 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936562	2,493,774 - 2,689,731 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936562	2,685,209 - 2,687,751 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CHRM4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	16,122,704 - 16,130,810 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	16,119,794 - 16,131,080 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	17,468,644 - 17,476,868 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Chrm4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624767	2,162,712 - 2,171,012 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624767	2,162,719 - 2,170,921 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	endocrine system	hemolymphoid system	nervous system
High
Medium			20
Low	20	10	40
Below cutoff	15	7

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008000215	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008000222	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000019300 ⟹ ENSCSAP00000018720

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	1	18,942,643 - 18,944,079 (+)	Ensembl

RefSeq Acc Id:

XM_008000215 ⟹ XP_007998406

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	1	18,937,456 - 18,945,390 (+)	NCBI
Vero_WHO_p1.0	NW_023666038	116,222,834 - 116,230,831 (+)	NCBI

Sequence:

show sequence

CGTCCCCGCCCCCGGCCCTCGGCCGGGCCGCCTGCCCCGCTGGCCCGCGGGGCCGCGCGTCCGT
CCCGCCGTCTGTCTGGCGTGAGGGGAGCTGGGCAGAGGCGGCGGGTAAGTGGCTCCGCGGCGGC
GCGGGGGCGGGGGGCTCGCCGGGAAGAGCAGGAAGCAGGTCCCCGGGACGCTCTGAGGCTCCCC
AGAGACACGGCCTACCCACCCCTGACAACCAACATGGCCAACTTCACACCTGTCAATGGCAGCT
CGGGCAATCAGTCCGTGCGCCTGGTCACGTCATCAACCCACAATCGCTACGAGACGGTGGAAAT
GGTCTTCATTGCCACAGTGACAGGCTCCCTGAGCCTGGTGACTGTCGTGGGCAACATCCTGGTG
ATGCTGTCCATCAAGGTCAACAGGCAGCTGCAGACAGTCAACAACTACTTCCTCTTCAGCCTGG
CATGTGCTGATCTCATCATAGGCGCCTTCTCCATGAACCTCTACACCGTGTACATCATCAAGGG
CTACTGGCCCCTGGGCGCTGTGGTCTGTGACCTGTGGCTGGCCCTGGACTACGTGGTGAGCAAT
GCCTCCGTCATGAACCTTCTCATCATCAGCTTTGACCGCTACTTCTGCGTCACCAAGCCCCTCA
CCTACCCTGCGCGGCGTACCACCAAGATGGCAGGCCTCATGATTGCCGCTGCCTGGGTTCTGTC
CTTCGTGCTCTGGGCGCCTGCCATTTTGTTCTGGCAGTTTGTGGTGGGCAAGAGGACAGTGCCC
GACAACCAGTGCTTCATCCAGTTCCTGTCCAACCCAGCAGTGACCTTCGGCACAGCCATCGCTG
CCTTCTACCTGCCTGTGGTCATCATGACGGTGCTGTACATCCACATCTCCCTGGCCAGTCGCAG
CCGAGTCCACAAGCACCGGCCCGAAGGCCCGAAGGAGAAGAAAGCCAAGACGTTGGCCTTCCTC
AAGAGCCCACTAATGAAGCAGAGCGTCAAGAAGCCCCCACCCGGGGAGGCCGCCCGGGAGGAGC
TGCGCAACGGCAAGCTGGAGGAGGCCCCCCCGCCGGCACTGCCACCACCACCACGCCCCATGAC
TGACAAGGACACTTCCAATGAGTCCAGCTCAGGCAGTGCCACCCAGAACACCAAGGAACGCCCA
GCCACAGAGCTGTCCACCACAGAGGCCACCACACCCGCCATGCCCGCCCCTTCCCTGCAGCCGC
GGGCCCTCAACCCAGCTTCCAAATGGTCCAAGATCCAGATCGTGACAAAGCAGACAGGCAATGA
GTGTGTGACAGCCATTGAGATTGTGCCTGCCACGCCTGCTGGCATGCGCCCTGCGGCCAACGTG
GCCCGCAAGTTCGCCAGCATCGCTCGCAATCAGGTGCGCAAGAAGCGGCAGATGGCGGCCCGGG
AGCGCAAAGTGACACGAACGATCTTTGCCATTCTGCTAGCCTTCATCCTCACCTGGACACCCTA
CAACGTCATGGTCCTGGTGAACACCTTCTGCCAGAGCTGCATCCCTGACACAGTGTGGTCCATT
GGCTACTGGCTCTGCTACGTCAACAGCACCATCAACCCTGCCTGCTATGCTCTGTGCAACGCCA
CCTTTAAAAAGACCTTCCGGCACCTGCTGCTGTGCCAGTATCGGAACATTGGCACTGCCAGGTA
GGCAGGCAGGAGTGCCCTAGGAGGTGCTGGTGTTGCGTGCGTCTGCTGGGGGACCACACGGCTC
ACCTGCTGTGGGGAAGAGTTGCAGGCACCATTCCGTGTTCATGTTTGCTGAGGAGGAAGCTCAG
AAGAGGCTCTGGCTGCATTCAGAGACCAGCTCTCTGCTCAGGCTGAGGAGGCTCACCCCAGGGA
ATGTCTGAATTGGGGCTGCCTGGCCCACCTCTGTGGCCCTGCTTCCACGAGCTGCGGGGCACTG
GCCTGGGTGGGCACCTGCCCCACTGTGGCCATCAGCAGTGCTGAGAGAATGGACATCTGGATGG
GGGCCGAAGCCCAGGGCCCCTCAGGAGGAACAGAGGGACCAGTGCTTGGAAAAGGAGGCTTGGG
ATGGGAGTAGAAGGGTTGGAGTCCCCCATTCTGCTGTAATCGGTGCTTTCTGCCCCCCTGCACC
CTGCATGTAGGCTCAGCCCCCTCTCCCCAAATCCCACTCCAGGGGCAGAACTCTCTGGCTGCAG
CTACTTAGCCAGGTTCTGGGTGGGTATGGTGGAGGCCAGGTCCCCCCAACCCCAGCAGCACTGC
CCTTGTCACATTACAACGGGGCAGCTGGGAGGTCAGGGGTTCTCTCTCAGGAACTGAGGTCTGG
CCTCCTCCGATCCCAGGCTGAGCTGAGAGTGGTCCGCTTATTCAGAAGACAGCCCCCTGCGGCC
CCAGCCTTAGAAGGCTGTCCCAGGTCGCACATCGAGTCAGGGTGAGGCTGTGGTGGGCGGCATT
CCCATCCACCCTTTTCAAACCTCTCGCCCTCTGGCTTCTGCAGGGTGGAGGCCTGGGTCACACA
GGCAAGAGGAAAGGGGTCGACCTGGTGGCTCACTCGGGTTTCCATGACAGTGGGAAGGGGGAGG
TGGGCAGTGAGGTAGGCACGCAACCCCCGCATCTGCTCTCCCCCAATGGGTAGAACCTTCCTGA
TTGGCTGTGAGTTGGATCAAAAGACCTTTGGGCGAGGCTGAGATGGGTGCGGCGGTTCCAGTGA
GTCAGCCAGGTTCCCTTCCCCAGCCCTGGTCCCTGGGGGAGATGAGGACCGAGAGGCTTAGGTG
ACTTGATGGCAGTCACCCTTTCGGGGGCCCTAGAAGAAATTTTCGTAATTGTTCTGCTTTTTCC
ATGAGCTCTGGAGAGCACCCACCACCAAGCCCCCAACCCCTGAAACCCACCAGTCCCTACAGCC
TGGTCCTTCTCCCCACCTTCCCACTCCCAAACACATTTCCACAGCAAACTCCTTGGGAAGGGGC
TTTTATATATTAAAAAAGAAAAGCTTTTA

hide sequence

RefSeq Acc Id:

XM_008000222 ⟹ XP_007998413

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	1	18,937,455 - 18,945,390 (+)	NCBI
Vero_WHO_p1.0	NW_023666038	116,222,834 - 116,230,831 (+)	NCBI

Sequence:

show sequence

CCGTCCCCGCCCCCGGCCCTCGGCCGGGCCGCCTGCCCCGCTGGCCCGCGGGGCCGCGCGTCCG
TCCCGCCGTCTGTCTGGCGTGAGGGGAGCTGGGCAGAGGCGGCGGACACGGCCTACCCACCCCT
GACAACCAACATGGCCAACTTCACACCTGTCAATGGCAGCTCGGGCAATCAGTCCGTGCGCCTG
GTCACGTCATCAACCCACAATCGCTACGAGACGGTGGAAATGGTCTTCATTGCCACAGTGACAG
GCTCCCTGAGCCTGGTGACTGTCGTGGGCAACATCCTGGTGATGCTGTCCATCAAGGTCAACAG
GCAGCTGCAGACAGTCAACAACTACTTCCTCTTCAGCCTGGCATGTGCTGATCTCATCATAGGC
GCCTTCTCCATGAACCTCTACACCGTGTACATCATCAAGGGCTACTGGCCCCTGGGCGCTGTGG
TCTGTGACCTGTGGCTGGCCCTGGACTACGTGGTGAGCAATGCCTCCGTCATGAACCTTCTCAT
CATCAGCTTTGACCGCTACTTCTGCGTCACCAAGCCCCTCACCTACCCTGCGCGGCGTACCACC
AAGATGGCAGGCCTCATGATTGCCGCTGCCTGGGTTCTGTCCTTCGTGCTCTGGGCGCCTGCCA
TTTTGTTCTGGCAGTTTGTGGTGGGCAAGAGGACAGTGCCCGACAACCAGTGCTTCATCCAGTT
CCTGTCCAACCCAGCAGTGACCTTCGGCACAGCCATCGCTGCCTTCTACCTGCCTGTGGTCATC
ATGACGGTGCTGTACATCCACATCTCCCTGGCCAGTCGCAGCCGAGTCCACAAGCACCGGCCCG
AAGGCCCGAAGGAGAAGAAAGCCAAGACGTTGGCCTTCCTCAAGAGCCCACTAATGAAGCAGAG
CGTCAAGAAGCCCCCACCCGGGGAGGCCGCCCGGGAGGAGCTGCGCAACGGCAAGCTGGAGGAG
GCCCCCCCGCCGGCACTGCCACCACCACCACGCCCCATGACTGACAAGGACACTTCCAATGAGT
CCAGCTCAGGCAGTGCCACCCAGAACACCAAGGAACGCCCAGCCACAGAGCTGTCCACCACAGA
GGCCACCACACCCGCCATGCCCGCCCCTTCCCTGCAGCCGCGGGCCCTCAACCCAGCTTCCAAA
TGGTCCAAGATCCAGATCGTGACAAAGCAGACAGGCAATGAGTGTGTGACAGCCATTGAGATTG
TGCCTGCCACGCCTGCTGGCATGCGCCCTGCGGCCAACGTGGCCCGCAAGTTCGCCAGCATCGC
TCGCAATCAGGTGCGCAAGAAGCGGCAGATGGCGGCCCGGGAGCGCAAAGTGACACGAACGATC
TTTGCCATTCTGCTAGCCTTCATCCTCACCTGGACACCCTACAACGTCATGGTCCTGGTGAACA
CCTTCTGCCAGAGCTGCATCCCTGACACAGTGTGGTCCATTGGCTACTGGCTCTGCTACGTCAA
CAGCACCATCAACCCTGCCTGCTATGCTCTGTGCAACGCCACCTTTAAAAAGACCTTCCGGCAC
CTGCTGCTGTGCCAGTATCGGAACATTGGCACTGCCAGGTAGGCAGGCAGGAGTGCCCTAGGAG
GTGCTGGTGTTGCGTGCGTCTGCTGGGGGACCACACGGCTCACCTGCTGTGGGGAAGAGTTGCA
GGCACCATTCCGTGTTCATGTTTGCTGAGGAGGAAGCTCAGAAGAGGCTCTGGCTGCATTCAGA
GACCAGCTCTCTGCTCAGGCTGAGGAGGCTCACCCCAGGGAATGTCTGAATTGGGGCTGCCTGG
CCCACCTCTGTGGCCCTGCTTCCACGAGCTGCGGGGCACTGGCCTGGGTGGGCACCTGCCCCAC
TGTGGCCATCAGCAGTGCTGAGAGAATGGACATCTGGATGGGGGCCGAAGCCCAGGGCCCCTCA
GGAGGAACAGAGGGACCAGTGCTTGGAAAAGGAGGCTTGGGATGGGAGTAGAAGGGTTGGAGTC
CCCCATTCTGCTGTAATCGGTGCTTTCTGCCCCCCTGCACCCTGCATGTAGGCTCAGCCCCCTC
TCCCCAAATCCCACTCCAGGGGCAGAACTCTCTGGCTGCAGCTACTTAGCCAGGTTCTGGGTGG
GTATGGTGGAGGCCAGGTCCCCCCAACCCCAGCAGCACTGCCCTTGTCACATTACAACGGGGCA
GCTGGGAGGTCAGGGGTTCTCTCTCAGGAACTGAGGTCTGGCCTCCTCCGATCCCAGGCTGAGC
TGAGAGTGGTCCGCTTATTCAGAAGACAGCCCCCTGCGGCCCCAGCCTTAGAAGGCTGTCCCAG
GTCGCACATCGAGTCAGGGTGAGGCTGTGGTGGGCGGCATTCCCATCCACCCTTTTCAAACCTC
TCGCCCTCTGGCTTCTGCAGGGTGGAGGCCTGGGTCACACAGGCAAGAGGAAAGGGGTCGACCT
GGTGGCTCACTCGGGTTTCCATGACAGTGGGAAGGGGGAGGTGGGCAGTGAGGTAGGCACGCAA
CCCCCGCATCTGCTCTCCCCCAATGGGTAGAACCTTCCTGATTGGCTGTGAGTTGGATCAAAAG
ACCTTTGGGCGAGGCTGAGATGGGTGCGGCGGTTCCAGTGAGTCAGCCAGGTTCCCTTCCCCAG
CCCTGGTCCCTGGGGGAGATGAGGACCGAGAGGCTTAGGTGACTTGATGGCAGTCACCCTTTCG
GGGGCCCTAGAAGAAATTTTCGTAATTGTTCTGCTTTTTCCATGAGCTCTGGAGAGCACCCACC
ACCAAGCCCCCAACCCCTGAAACCCACCAGTCCCTACAGCCTGGTCCTTCTCCCCACCTTCCCA
CTCCCAAACACATTTCCACAGCAAACTCCTTGGGAAGGGGCTTTTATATATTAAAAAAGAAAAG
CTTTTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_007998406	(Get FASTA)	NCBI Sequence Viewer
	XP_007998413	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000018720
	ENSCSAP00000018720.1

RefSeq Acc Id:	XP_007998413 ⟸ XM_008000222
- UniProtKB:	A0A0D9SCY1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_007998406 ⟸ XM_008000215
- UniProtKB:	A0A0D9SCY1 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCSAP00000018720 ⟸ ENSCSAT00000019300

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000019210	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000019300.1	UniProtKB/TrEMBL
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/TrEMBL
InterPro	GPCR_Rhodpsn	UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/TrEMBL
	Musac_Ach_M4_rcpt	UniProtKB/TrEMBL
	Musac_Ach_rcpt	UniProtKB/TrEMBL
KEGG Report	csab:103236497	UniProtKB/TrEMBL
NCBI Gene	CHRM4	ENTREZGENE
PANTHER	5-HYDROXYTRYPTAMINE RECEPTOR	UniProtKB/TrEMBL
	MUSCARINIC ACETYLCHOLINE RECEPTOR M4	UniProtKB/TrEMBL
Pfam	7tm_1	UniProtKB/TrEMBL
PRINTS	GPCRRHODOPSN	UniProtKB/TrEMBL
	MUSCARINICR	UniProtKB/TrEMBL
	MUSCRINICM4R	UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/TrEMBL
SMART	7TM_GPCR_Srsx	UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/TrEMBL
UniProt	A0A0D9SCY1	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations