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Gene: Tp53bp1 (tumor protein p53 binding protein 1) Rattus norvegicus
Symbol: Tp53bp1
Name: tumor protein p53 binding protein 1
RGD ID: 1308039
Description: Predicted to have several functions, including DNA binding activity; RNA polymerase II activating transcription factor binding activity; and histone binding activity. Involved in cellular response to X-ray. Localizes to nucleus. Predicted to colocalize with chromosome, telomeric region. Orthologous to human TP53BP1 (tumor protein p53 binding protein 1); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; non-homologous end joining pathway of double-strand break repair; INTERACTS WITH all-trans-retinoic acid; bisphenol A; thioacetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC296099; transformation related protein 53 binding protein 1; Trp53bp1; tumor suppressor p53-binding protein 1
Homo sapiens (human) : TP53BP1 (tumor protein p53 binding protein 1)  HGNC  Alliance
Mus musculus (house mouse) : Trp53bp1 (transformation related protein 53 binding protein 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tp53bp1 (tumor protein p53 binding protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TP53BP1 (tumor protein p53 binding protein 1)
Canis lupus familiaris (dog) : TP53BP1 (tumor protein p53 binding protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tp53bp1 (tumor protein p53 binding protein 1)
Sus scrofa (pig) : TP53BP1 (tumor protein p53 binding protein 1)
Chlorocebus sabaeus (African green monkey) : TP53BP1 (tumor protein p53 binding protein 1)
Heterocephalus glaber (naked mole-rat) : Tp53bp1 (tumor protein p53 binding protein 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03113,160,030 - 113,259,701 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3113,160,000 - 113,231,790 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03119,697,122 - 119,799,485 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43107,994,425 - 108,071,133 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13107,897,216 - 107,968,850 (-)NCBI
Celera3107,073,150 - 107,144,062 (-)NCBICelera
Cytogenetic Map3q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Tp53bp1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308039
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-09-15
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.