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Gene: Zfp106 (zinc finger protein 106) Rattus norvegicus

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Symbol:

Zfp106

Name:

zinc finger protein 106

RGD ID:

1593644

Description:

Predicted to enable SH3 domain binding activity and opioid peptide activity. Predicted to be involved in insulin receptor signaling pathway. Predicted to be active in cytosol and membrane. Orthologous to human ZNF106 (zinc finger protein 106); INTERACTS WITH 17beta-estradiol; acrylamide; aflatoxin B1.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC688018; similar to SH3-domain binding protein 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	127,912,981 - 127,964,254 (-)	NCBI		GRCr8
mRatBN7.2	3	107,459,232 - 107,510,507 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	107,462,096 - 107,510,481 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	3	112,279,782 - 112,330,288 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	112,283,112 - 112,320,762 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	118,827,186 - 118,857,322 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	3	106,368,014 - 106,418,966 (-)	NCBI		Celera
Cytogenetic Map	3	q35	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Zfp106	Rat	Bloom syndrome		ISO	ZNF106 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Bloom syndrome	ClinVar	PMID:28492532
Zfp106	Rat	colorectal cancer		ISO	ZNF106 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Familial colorectal cancer	ClinVar	PMID:28492532

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Zfp106	Rat	amyotrophic lateral sclerosis		ISS	Zfp106 (Mus musculus)	13592920		MouseDO

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Zfp106	Rat	17alpha-ethynylestradiol	affects expression	ISO	Zfp106 (Mus musculus)	6480464	Ethinyl Estradiol affects the expression of ZFP106 mRNA	CTD	PMID:17555576
Zfp106	Rat	17beta-estradiol	decreases expression	EXP		6480464	Estradiol results in decreased expression of ZFP106 mRNA	CTD	PMID:32145629
Zfp106	Rat	17beta-estradiol	increases expression	ISO	Zfp106 (Mus musculus)	6480464	Estradiol results in increased expression of ZFP106 mRNA	CTD	PMID:39298647
Zfp106	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	Zfp106 (Mus musculus)	6480464	Tetrachlorodibenzodioxin affects the expression of ZFP106 mRNA	CTD	PMID:24680724
Zfp106	Rat	2-methylcholine	affects expression	ISO	ZNF106 (Homo sapiens)	6480464	beta-methylcholine affects the expression of ZNF106 mRNA	CTD	PMID:21179406
Zfp106	Rat	acrylamide	decreases expression	EXP		6480464	Acrylamide results in decreased expression of ZFP106 mRNA	CTD	PMID:28959563
Zfp106	Rat	acrylamide	increases expression	ISO	ZNF106 (Homo sapiens)	6480464	Acrylamide results in increased expression of ZNF106 mRNA	CTD	PMID:32763439
Zfp106	Rat	aflatoxin B1	increases expression	ISO	Zfp106 (Mus musculus)	6480464	Aflatoxin B1 results in increased expression of ZFP106 mRNA	CTD	PMID:19770486
Zfp106	Rat	aflatoxin B1	decreases expression	EXP		6480464	Aflatoxin B1 results in decreased expression of ZFP106 mRNA	CTD	PMID:33354967
Zfp106	Rat	aflatoxin B1	decreases methylation	ISO	ZNF106 (Homo sapiens)	6480464	Aflatoxin B1 results in decreased methylation of ZNF106 intron	CTD	PMID:30157460
Zfp106	Rat	Aflatoxin B2 alpha	increases methylation	ISO	ZNF106 (Homo sapiens)	6480464	aflatoxin B2 results in increased methylation of ZNF106 intron	CTD	PMID:30157460
Zfp106	Rat	all-trans-retinoic acid	increases expression	ISO	ZNF106 (Homo sapiens)	6480464	Tretinoin results in increased expression of ZNF106 mRNA	CTD	PMID:33167477
Zfp106	Rat	antirheumatic drug	increases expression	ISO	ZNF106 (Homo sapiens)	6480464	Antirheumatic Agents results in increased expression of ZFP106 mRNA	CTD	PMID:24449571
Zfp106	Rat	arsane	multiple interactions	ISO	ZNF106 (Homo sapiens)	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of ZNF106 mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of ZNF106 mRNA	CTD	PMID:39836092
Zfp106	Rat	arsenic atom	multiple interactions	ISO	ZNF106 (Homo sapiens)	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of ZNF106 mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of ZNF106 mRNA	CTD	PMID:39836092
Zfp106	Rat	arsenite(3-)	multiple interactions	ISO	ZNF106 (Homo sapiens)	6480464	arsenite inhibits the reaction [G3BP1 protein binds to ZNF106 mRNA]	CTD	PMID:32406909
Zfp106	Rat	benzo[a]pyrene	increases expression	ISO	Zfp106 (Mus musculus)	6480464	Benzo(a)pyrene results in increased expression of ZFP106 mRNA	CTD	PMID:22228805
Zfp106	Rat	bis(2-ethylhexyl) phthalate	decreases expression	ISO	Zfp106 (Mus musculus)	6480464	Diethylhexyl Phthalate results in decreased expression of ZFP106 mRNA	CTD	PMID:33754040
Zfp106	Rat	bisphenol A	increases expression	ISO	ZNF106 (Homo sapiens)	6480464	bisphenol A results in increased expression of ZNF106 mRNA	CTD	PMID:29275510
Zfp106	Rat	bisphenol A	affects expression	EXP		6480464	bisphenol A affects the expression of ZFP106 mRNA	CTD	PMID:32145629
Zfp106	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of ZFP106 mRNA	CTD	PMID:30816183
Zfp106	Rat	cadmium dichloride	increases expression	ISO	ZNF106 (Homo sapiens)	6480464	Cadmium Chloride results in increased expression of ZNF106 mRNA	CTD	PMID:38382870
Zfp106	Rat	caffeine	decreases phosphorylation	ISO	ZNF106 (Homo sapiens)	6480464	Caffeine results in decreased phosphorylation of ZNF106 protein	CTD	PMID:35688186
Zfp106	Rat	carbamazepine	affects expression	ISO	ZNF106 (Homo sapiens)	6480464	Carbamazepine affects the expression of ZNF106 mRNA	CTD	PMID:25979313
Zfp106	Rat	CGP 52608	multiple interactions	ISO	ZNF106 (Homo sapiens)	6480464	CGP 52608 promotes the reaction [RORA protein binds to ZFP106 gene]	CTD	PMID:28238834
Zfp106	Rat	chlorpyrifos	decreases expression	ISO	Zfp106 (Mus musculus)	6480464	Chlorpyrifos results in decreased expression of ZFP106 mRNA	CTD	PMID:20350560 and PMID:37019170
Zfp106	Rat	coumarin	decreases phosphorylation	ISO	ZNF106 (Homo sapiens)	6480464	coumarin results in decreased phosphorylation of ZNF106 protein	CTD	PMID:35688186
Zfp106	Rat	dicrotophos	increases expression	ISO	ZNF106 (Homo sapiens)	6480464	dicrotophos results in increased expression of ZNF106 mRNA	CTD	PMID:28302478
Zfp106	Rat	diuron	decreases expression	EXP		6480464	Diuron results in decreased expression of ZFP106 mRNA	CTD	PMID:25152437
Zfp106	Rat	doxorubicin	decreases expression	ISO	ZNF106 (Homo sapiens)	6480464	Doxorubicin results in decreased expression of ZNF106 mRNA	CTD	PMID:29803840
Zfp106	Rat	ethanol	increases expression	ISO	Zfp106 (Mus musculus)	6480464	Ethanol results in increased expression of ZFP106 mRNA	CTD	PMID:30319688
Zfp106	Rat	ethanol	affects splicing	ISO	Zfp106 (Mus musculus)	6480464	Ethanol affects the splicing of ZFP106 mRNA	CTD	PMID:30319688
Zfp106	Rat	finasteride	increases expression	EXP		6480464	Finasteride results in increased expression of ZFP106 mRNA	CTD	PMID:24136188
Zfp106	Rat	folic acid	decreases expression	ISO	Zfp106 (Mus musculus)	6480464	Folic Acid results in decreased expression of ZFP106 mRNA	CTD	PMID:25629700
Zfp106	Rat	FR900359	affects phosphorylation	ISO	ZNF106 (Homo sapiens)	6480464	FR900359 affects the phosphorylation of ZNF106 protein	CTD	PMID:37730182
Zfp106	Rat	lead(0)	affects expression	ISO	ZNF106 (Homo sapiens)	6480464	Lead affects the expression of ZNF106 mRNA	CTD	PMID:22313790
Zfp106	Rat	manganese atom	multiple interactions	ISO	ZNF106 (Homo sapiens)	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of ZNF106 mRNA and [manganese chloride results in increased abundance of Manganese] which results in decreased expression of ZNF106 mRNA	CTD	PMID:39836092
Zfp106	Rat	manganese(0)	multiple interactions	ISO	ZNF106 (Homo sapiens)	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of ZNF106 mRNA and [manganese chloride results in increased abundance of Manganese] which results in decreased expression of ZNF106 mRNA	CTD	PMID:39836092
Zfp106	Rat	manganese(II) chloride	multiple interactions	ISO	ZNF106 (Homo sapiens)	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of ZNF106 mRNA and [manganese chloride results in increased abundance of Manganese] which results in decreased expression of ZNF106 mRNA	CTD	PMID:39836092
Zfp106	Rat	nickel dichloride	decreases expression	ISO	ZNF106 (Homo sapiens)	6480464	nickel chloride results in decreased expression of ZNF106 mRNA	CTD	PMID:17312168
Zfp106	Rat	p-toluidine	increases expression	EXP		6480464	4-toluidine results in increased expression of ZNF106 mRNA	CTD	PMID:27638505
Zfp106	Rat	paracetamol	increases expression	ISO	ZNF106 (Homo sapiens)	6480464	Acetaminophen results in increased expression of ZNF106 mRNA	CTD	PMID:22230336
Zfp106	Rat	paracetamol	affects expression	ISO	Zfp106 (Mus musculus)	6480464	Acetaminophen affects the expression of ZFP106 mRNA	CTD	PMID:17562736
Zfp106	Rat	paracetamol	decreases expression	ISO	ZNF106 (Homo sapiens)	6480464	Acetaminophen results in decreased expression of ZNF106 mRNA	CTD	PMID:21420995
Zfp106	Rat	perfluorohexanesulfonic acid	decreases expression	ISO	Zfp106 (Mus musculus)	6480464	perfluorohexanesulfonic acid results in decreased expression of ZFP106 mRNA	CTD	PMID:37995155
Zfp106	Rat	pirinixic acid	increases expression	ISO	Zfp106 (Mus musculus)	6480464	pirinixic acid results in increased expression of ZFP106 mRNA	CTD	PMID:23811191
Zfp106	Rat	resveratrol	multiple interactions	ISO	ZNF106 (Homo sapiens)	6480464	[Plant Extracts co-treated with Resveratrol] results in increased expression of ZFP106 mRNA	CTD	PMID:23557933
Zfp106	Rat	senecionine	increases expression	ISO	Zfp106 (Mus musculus)	6480464	senecionine results in increased expression of ZNF106 protein	CTD	PMID:35357534
Zfp106	Rat	sodium arsenite	multiple interactions	ISO	ZNF106 (Homo sapiens)	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of ZNF106 mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of ZNF106 mRNA	CTD	PMID:39836092
Zfp106	Rat	sulindac	decreases expression	EXP		6480464	Sulindac results in decreased expression of ZFP106 mRNA	CTD	PMID:24136188
Zfp106	Rat	tamoxifen	affects expression	ISO	Zfp106 (Mus musculus)	6480464	Tamoxifen affects the expression of ZFP106 mRNA	CTD	PMID:17555576
Zfp106	Rat	testosterone	decreases expression	ISO	ZNF106 (Homo sapiens)	6480464	Testosterone results in decreased expression of ZNF106 mRNA	CTD	PMID:33359661
Zfp106	Rat	tetrachloromethane	increases expression	ISO	Zfp106 (Mus musculus)	6480464	Carbon Tetrachloride results in increased expression of ZFP106 mRNA	CTD	PMID:31919559
Zfp106	Rat	thiram	increases expression	ISO	ZNF106 (Homo sapiens)	6480464	Thiram results in increased expression of ZNF106 mRNA	CTD	PMID:38568856
Zfp106	Rat	titanium dioxide	decreases methylation	ISO	Zfp106 (Mus musculus)	6480464	titanium dioxide results in decreased methylation of ZFP106 promoter alternative form	CTD	PMID:35295148
Zfp106	Rat	trimellitic anhydride	increases expression	ISO	Zfp106 (Mus musculus)	6480464	trimellitic anhydride results in increased expression of ZFP106 mRNA	CTD	PMID:19042947
Zfp106	Rat	triptonide	increases expression	ISO	Zfp106 (Mus musculus)	6480464	triptonide results in increased expression of ZFP106 mRNA	CTD	PMID:33045310
Zfp106	Rat	tungsten	decreases expression	ISO	Zfp106 (Mus musculus)	6480464	Tungsten results in decreased expression of ZFP106 mRNA	CTD	PMID:30912803
Zfp106	Rat	tunicamycin	decreases expression	ISO	Zfp106 (Mus musculus)	6480464	Tunicamycin results in decreased expression of ZFP106 mRNA	CTD	PMID:17127020
Zfp106	Rat	valproic acid	affects expression	ISO	ZNF106 (Homo sapiens)	6480464	Valproic Acid affects the expression of ZNF106 mRNA	CTD	PMID:25979313
Zfp106	Rat	valproic acid	affects splicing	EXP		6480464	Valproic Acid affects the splicing of ZFP106 mRNA	CTD	PMID:29427782

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Zfp106	Rat	insulin receptor signaling pathway	involved_in	IBA	MGI:1270153 and PANTHER:PTN002683585	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Zfp106	Rat	insulin receptor signaling pathway	acts_upstream_of_or_within	ISO	Zfp106 (Mus musculus)	1624291	PMID:9507006	RGD	PMID:9507006

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Zfp106	Rat	cytosol	is_active_in	IBA	MGI:1270153 and PANTHER:PTN001024903	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Zfp106	Rat	cytosol	located_in	ISO	Zfp106 (Mus musculus)	1624291	PMID:9507006	RGD	PMID:9507006
Zfp106	Rat	membrane	is_active_in	IBA	MGI:1270153 and PANTHER:PTN001024903	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Zfp106	Rat	membrane	located_in	ISO	Zfp106 (Mus musculus)	1624291	PMID:9507006	RGD	PMID:9507006

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Zfp106	Rat	opioid peptide activity	enables	ISO	Zfp106 (Mus musculus)	1624291	PR:P39688 more ...	RGD	PMID:9507006
Zfp106	Rat	protein binding	enables	ISO	ZNF106 (Homo sapiens)	1624291	UniProtKB:Q92793 and PMID:28680062	RGD	PMID:28680062
Zfp106	Rat	RNA binding	enables	IEA	InterPro:IPR042622	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Zfp106	Rat	SH3 domain binding	enables	ISO	Zfp106 (Mus musculus)	1624291	PMID:9507006	RGD	PMID:9507006

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:9507006	PMID:12477932	PMID:22658674

Zfp106
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	127,912,981 - 127,964,254 (-)	NCBI		GRCr8
mRatBN7.2	3	107,459,232 - 107,510,507 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	107,462,096 - 107,510,481 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	3	112,279,782 - 112,330,288 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	112,283,112 - 112,320,762 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	118,827,186 - 118,857,322 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	3	106,368,014 - 106,418,966 (-)	NCBI		Celera
Cytogenetic Map	3	q35	NCBI

ZNF106
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	42,412,823 - 42,491,141 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	42,412,823 - 42,491,141 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	42,705,021 - 42,783,339 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	40,492,313 - 40,537,019 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	15	40,492,313 - 40,537,022	NCBI
Celera	15	19,472,730 - 19,517,437 (-)	NCBI		Celera
Cytogenetic Map	15	q15.1	NCBI
HuRef	15	19,553,142 - 19,597,638 (-)	NCBI		HuRef
CHM1_1	15	42,823,506 - 42,868,172 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	15	40,218,871 - 40,297,183 (-)	NCBI		T2T-CHM13v2.0

Zfp106
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	120,337,303 - 120,394,345 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	120,337,301 - 120,394,324 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	120,506,820 - 120,563,864 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	120,506,820 - 120,563,843 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	120,332,566 - 120,389,567 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	120,201,054 - 120,255,231 (-)	NCBI		MGSCv36	mm8
Celera	2	121,660,934 - 121,716,678 (-)	NCBI		Celera
Cytogenetic Map	2	E5	NCBI
cM Map	2	60.37	NCBI

Znf106
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955416	9,118,812 - 9,183,583 (-)	NCBI	ChiLan1.0	ChiLan1.0

ZNF106
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	31,662,415 - 31,741,644 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	35,815,641 - 35,898,578 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	21,372,911 - 21,452,149 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	39,529,324 - 39,608,427 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	39,533,822 - 39,608,427 (-)	Ensembl	panpan1.1		panPan2

TMEM87A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	30	9,215,585 - 9,253,712 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	30	9,216,702 - 9,253,700 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	30	9,273,738 - 9,311,932 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	30	9,350,326 - 9,388,853 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	30	9,350,330 - 9,388,833 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	30	9,270,636 - 9,308,807 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	30	9,375,705 - 9,414,213 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	30	9,509,957 - 9,548,150 (-)	NCBI		UU_Cfam_GSD_1.0

Znf106
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	87,864,589 - 87,931,764 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936471	5,712,655 - 5,779,827 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ZNF106
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	128,893,971 - 128,957,305 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	128,893,965 - 128,957,334 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	143,786,697 - 143,851,832 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ZNF106
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	40,486,801 - 40,567,811 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	26	40,486,913 - 40,563,332 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	100,446,196 - 100,525,254 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Znf106
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624804	9,513,090 - 9,606,758 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Zfp106
141 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	144
Count of miRNA genes:	113
Interacting mature miRNAs:	121
Transcripts:	ENSRNOT00000070976, ENSRNOT00000072405
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2312673	Scl63	Serum cholesterol level QTL 63		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	98535255	168026850	Rat
2301414	Kidm37	Kidney mass QTL 37		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	70653097	121056321	Rat
1582238	Bw68	Body weight QTL 68	3.2	0.0064	body mass (VT:0001259)	body weight (CMO:0000012)	3	53184593	115665732	Rat
2302373	Gluco39	Glucose level QTL 39	5.01		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	3	98535386	161695835	Rat
1582239	Epfw1	Epididymal fat weight QTL 1	4.5	0.0006	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	3	53184593	115665732	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	31172320	163586636	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	47233211	147415807	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	38192233	133483320	Rat
1582216	Bw65	Body weight QTL 65	6.3		body mass (VT:0001259)	body weight (CMO:0000012)	3	102200529	115665732	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	29463235	118376539	Rat
1582218	Bw74	Body weight QTL 74	3.9	0.0021	body mass (VT:0001259)	body weight (CMO:0000012)	3	53184593	115665732	Rat
1582219	Bw63	Body weight QTL 63	3.8	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	3	96127817	115665732	Rat
1582221	Kidm30	Kidney mass QTL 30	3.5	0.0008	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	3	64655305	115665732	Rat
1581568	Rf53	Renal function QTL 53			urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	3	56395968	161299569	Rat
1582210	Bw71	Body weight QTL 71	3.3	0.0012	body mass (VT:0001259)	body weight (CMO:0000012)	3	64655305	115665732	Rat
7387306	Bw124	Body weight QTL 124	3.2	0.0003	body mass (VT:0001259)	body weight (CMO:0000012)	3	84091273	129091273	Rat
1300111	Rf12	Renal function QTL 12	3.78		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	61017749	121056321	Rat
724523	Tsu1	Thymus enlargement suppressive QTL 1	3.84		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	3	50437504	115638231	Rat
1600376	Arunc5	Aerobic running capacity QTL 5		0.21	exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	3	73376539	118376539	Rat
8694437	Bw167	Body weight QTL 167	22.46	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	3	91797474	136797474	Rat
2302273	Gluco35	Glucose level QTL 35	5.3	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	80800231	114297550	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	59242096	157323038	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	43827364	169034231	Rat
1581503	Cm58	Cardiac mass QTL 58	2.7	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	43827364	121056321	Rat
2292613	Ept16	Estrogen-induced pituitary tumorigenesis QTL 16	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	47233430	110362260	Rat
1354611	Despr2	Despair related QTL 2	3.03	0.0028	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	3	97084464	142084464	Rat
631649	Bp123	Blood pressure QTL 123	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	89772419	134772419	Rat
631841	Niddm39	Non-insulin dependent diabetes mellitus QTL 39	3.36		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	94856903	159898684	Rat
12879848	Bw181	Body weght QTL 181		0.015	body mass (VT:0001259)	body weight (CMO:0000012)	3	70348525	121056321	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	41874578	155617519	Rat
2312659	Slep7	Serum leptin concentration QTL 7		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	3	98535255	168026850	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	41874578	155617519	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	78196190	146592722	Rat
631665	Bw8	Body weight QTL 8	5.5		body mass (VT:0001259)	body weight (CMO:0000012)	3	50437042	119183768	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
2293087	Iddm27	Insulin dependent diabetes mellitus QTL 27	2.68		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	97551417	147415807	Rat
2312670	Bw94	Body weight QTL 94		0.01	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	3	98535255	168026850	Rat
1358186	Ept2	Estrogen-induced pituitary tumorigenesis QTL 2	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	47233430	110362260	Rat
724532	Cm17	Cardiac mass QTL 17	2		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	3	95735366	140735366	Rat

D3Rat20

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	3	127,917,802 - 127,917,917 (+)	Marker Load Pipeline
mRatBN7.2	3	107,464,053 - 107,464,168 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	112,284,604 - 112,284,718	NCBI	Rnor6.0
Rnor_5.0	3	118,832,008 - 118,832,122	UniSTS	Rnor5.0
Celera	3	106,372,836 - 106,372,950	UniSTS
RH 3.4 Map	3	948.0	RGD
RH 3.4 Map	3	948.0	UniSTS
RH 2.0 Map	3	609.0	RGD
SHRSP x BN Map	3	52.9098	RGD

RH128384

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	107,459,403 - 107,459,618 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	112,279,954 - 112,280,168	NCBI	Rnor6.0
Rnor_5.0	3	118,827,358 - 118,827,572	UniSTS	Rnor5.0
RGSC_v3.4	3	106,999,820 - 107,000,034	UniSTS	RGSC3.4
Celera	3	106,368,186 - 106,368,400	UniSTS
RH 3.4 Map	3	938.0	UniSTS

RH133910

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	107,475,857 - 107,476,076 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	112,296,412 - 112,296,631	NCBI	Rnor6.0
Celera	3	106,384,640 - 106,384,858	UniSTS
RH 3.4 Map	3	975.5	UniSTS

RH137886

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	107,509,502 - 107,509,629 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	112,329,302 - 112,329,428	NCBI	Rnor6.0
Rnor_5.0	3	118,876,579 - 118,876,705	UniSTS	Rnor5.0
Celera	3	106,417,981 - 106,418,107	UniSTS
RH 3.4 Map	3	938.0	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31


RefSeq Transcripts	NM_001419871	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008775485	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008775486	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008775487	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017592340	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039106519	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AY621078	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC166427	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ215666	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ225308	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000078893 ⟹ ENSRNOP00000072228

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	107,462,096 - 107,510,481 (-)	Ensembl
Rnor_6.0 Ensembl	3	112,283,112 - 112,320,762 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000081074 ⟹ ENSRNOP00000068586

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	107,462,096 - 107,487,979 (-)	Ensembl
Rnor_6.0 Ensembl	3	112,283,112 - 112,320,762 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000089857 ⟹ ENSRNOP00000070083

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	3	112,303,358 - 112,320,762 (-)	Ensembl

RefSeq Acc Id:

NM_001419871 ⟹ NP_001406800

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	127,912,981 - 127,964,254 (-)	NCBI
mRatBN7.2	3	107,459,232 - 107,510,507 (-)	NCBI

RefSeq Acc Id:

XM_039106519 ⟹ XP_038962447

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	127,912,983 - 127,964,249 (-)	NCBI
mRatBN7.2	3	107,459,232 - 107,510,493 (-)	NCBI


Protein RefSeqs	NP_001406800	(Get FASTA)	NCBI Sequence Viewer
	XP_038962447	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI66427	(Get FASTA)	NCBI Sequence Viewer
	AAT77251	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000068586.2
	ENSRNOP00000072228
	ENSRNOP00000072228.2

Ensembl Acc Id:

ENSRNOP00000070083 ⟸ ENSRNOT00000089857

Ensembl Acc Id:

ENSRNOP00000068586 ⟸ ENSRNOT00000081074

Ensembl Acc Id:

ENSRNOP00000072228 ⟸ ENSRNOT00000078893

RefSeq Acc Id:	XP_038962447 ⟸ XM_039106519
- Peptide Label:	isoform X1

RefSeq Acc Id:	NP_001406800 ⟸ NM_001419871
- UniProtKB:	A0A0G2K2F8 (UniProtKB/TrEMBL), A0A0G2JT65 (UniProtKB/TrEMBL)

Protein Domains

C2H2-type

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2JT65-F1-model_v2	AlphaFold	A0A0G2JT65	1-1881	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-48162	BioCyc
Ensembl Genes	ENSRNOG00000052583	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000078893	ENTREZGENE
	ENSRNOT00000078893.2	UniProtKB/TrEMBL
	ENSRNOT00000081074.2	UniProtKB/TrEMBL
Gene3D-CATH	2.130.10.10	UniProtKB/TrEMBL
InterPro	PQQ_beta_propeller_repeat	UniProtKB/TrEMBL
	WD40/YVTN_repeat-like_dom_sf	UniProtKB/TrEMBL
	WD40_repeat	UniProtKB/TrEMBL
	WD40_repeat_dom_sf	UniProtKB/TrEMBL
	Znf106	UniProtKB/TrEMBL
	Znf_C2H2_type	UniProtKB/TrEMBL
NCBI Gene	688018	ENTREZGENE
PANTHER	PTHR14435	UniProtKB/TrEMBL
	ZINC FINGER PROTEIN 106	UniProtKB/TrEMBL
Pfam	WD40	UniProtKB/TrEMBL
PhenoGen	Zfp106	PhenoGen
PROSITE	WD_REPEATS_2	UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_1	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000052583	RatGTEx
SMART	PQQ	UniProtKB/TrEMBL
	WD40	UniProtKB/TrEMBL
	ZnF_C2H2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50978	UniProtKB/TrEMBL
UniProt	A0A0G2JT65	ENTREZGENE, UniProtKB/TrEMBL
	A0A0G2K2F8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2014-10-27	Zfp106	zinc finger protein 106	LOC688018	similar to SH3-domain binding protein 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-20	LOC688018	similar to SH3-domain binding protein 3			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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