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Gene: B2m (beta-2 microglobulin) Rattus norvegicus
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Symbol: B2m
Name: beta-2 microglobulin
Description: Predicted to have identical protein binding activity. Involved in response to cadmium ion and response to drug. Localizes to the extracellular space. Biomarker of acute kidney failure; pyelonephritis; and ureteral obstruction. Human ortholog(s) of this gene implicated in arthritis; familial visceral amyloidosis; inflammatory bowel disease; and primary immunodeficiency disease. Orthologous to human B2M (beta-2-microglobulin); PARTICIPATES IN interleukin-12 signaling pathway; antigen processing and presentation pathway; INTERACTS WITH 1,3-dinitrobenzene; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Beta-2-microglobulin; beta-2-microglobulin C-terminal fragment (55 AA)
Orthologs:
Homo sapiens (human) : B2M (beta-2-microglobulin)  HGNC  Alliance
Mus musculus (house mouse) : B2m (beta-2 microglobulin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : B2m (beta-2-microglobulin)
Pan paniscus (bonobo/pygmy chimpanzee) : B2M (beta-2-microglobulin)
Canis lupus familiaris (dog) : B2M (beta-2-microglobulin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : B2m (beta-2-microglobulin)
Sus scrofa (pig) : B2M (beta-2-microglobulin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03114,087,287 - 114,093,311 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03120,627,499 - 120,633,523 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43108,927,919 - 108,932,718 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13108,833,491 - 108,838,291 (+)NCBI
Celera3107,993,988 - 108,000,012 (+)NCBICelera
Cytogenetic Map3q35NCBI
RH 3.4 Map3954.3RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on B2m
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2189
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.