Madd (MAP-kinase activating death domain) - Rat Genome Database

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Gene: Madd (MAP-kinase activating death domain) Rattus norvegicus
Analyze
Symbol: Madd
Name: MAP-kinase activating death domain
RGD ID: 619922
Description: Enables guanyl-nucleotide exchange factor activity. Involved in negative regulation of growth hormone secretion and negative regulation of pancreatic amylase secretion. Located in cytosol; nucleus; and synaptic vesicle. Is active in synapse. Biomarker of transient cerebral ischemia. Orthologous to human MADD (MAP kinase activating death domain); PARTICIPATES IN ceramide signaling pathway; tumor necrosis factor mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MAP kinase-activating death domain protein; rab3 GDP/GTP exchange factor; Rab3 GDP/GTP exchange protein; RabGEF; RabGEP
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Maddm1Mcwi  
Genetic Models: FHH-Maddm1Mcwi
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2377,114,330 - 77,157,865 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl377,114,314 - 77,157,701 (-)Ensembl
Rnor_6.0379,960,301 - 80,003,023 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl379,960,301 - 80,003,032 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0386,669,054 - 86,711,776 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4375,498,321 - 75,541,073 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1375,408,586 - 75,437,445 (-)NCBI
Celera376,323,258 - 76,366,073 (-)NCBICelera
Cytogenetic Map3q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. MADD/DENN/Rab3GEP functions as a guanine nucleotide exchange factor for Rab27 during granule exocytosis of rat parotid acinar cells. Imai A, etal., Arch Biochem Biophys. 2013 Aug 1;536(1):31-7. doi: 10.1016/j.abb.2013.05.002. Epub 2013 May 20.
3. A novel function of the C-terminal lipid moieties of Rab3A small G protein implicated in Ca2+-dependent exocytosis--inhibition of interaction with GTP and reduction of this inhibition by phospholipid. Jin-no Y, etal., Genes Cells. 1997 Apr;2(4):273-88.
4. A novel rabconnectin-3-binding protein that directly binds a GDP/GTP exchange protein for Rab3A small G protein implicated in Ca(2+)-dependent exocytosis of neurotransmitter. Kawabe H, etal., Genes Cells 2003 Jun;8(6):537-46.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. Localization of the Rab3 small G protein regulators in nerve terminals and their involvement in Ca2+-dependent exocytosis. Oishi H, etal., J Biol Chem. 1998 Dec 18;273(51):34580-5.
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Purification and properties of Rab3 GEP (DENN/MADD). Sakisaka T and Takai Y, Methods Enzymol. 2005;403:254-61.
14. The onset of apoptosis of neurons induced by ischemia-reperfusion injury is delayed by transient period of hypertension in rats. Smrcka M, etal., Physiol Res. 2003;52(1):117-22.
15. Isolation and characterization of a GDP/GTP exchange protein specific for the Rab3 subfamily small G proteins. Wada M, etal., J Biol Chem 1997 Feb 14;272(7):3875-8.
Additional References at PubMed
PMID:8988362   PMID:9115275   PMID:11577081   PMID:14735464   PMID:15007167   PMID:18849981   PMID:20937701   PMID:22871113   PMID:25931508   PMID:29476059   PMID:30053369  


Genomics

Comparative Map Data
Madd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2377,114,330 - 77,157,865 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl377,114,314 - 77,157,701 (-)Ensembl
Rnor_6.0379,960,301 - 80,003,023 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl379,960,301 - 80,003,032 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0386,669,054 - 86,711,776 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4375,498,321 - 75,541,073 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1375,408,586 - 75,437,445 (-)NCBI
Celera376,323,258 - 76,366,073 (-)NCBICelera
Cytogenetic Map3q24NCBI
MADD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381147,269,188 - 47,330,031 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1147,269,161 - 47,330,031 (+)EnsemblGRCh38hg38GRCh38
GRCh371147,290,739 - 47,351,582 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361147,247,535 - 47,308,158 (+)NCBINCBI36hg18NCBI36
Build 341147,248,259 - 47,308,157NCBI
Celera1147,430,145 - 47,490,862 (+)NCBI
Cytogenetic Map11p11.2NCBI
HuRef1146,989,904 - 47,050,670 (+)NCBIHuRef
CHM1_11147,290,116 - 47,350,822 (+)NCBICHM1_1
T2T-CHM13v2.01147,425,958 - 47,486,853 (+)NCBI
Madd
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39290,967,705 - 91,013,404 (-)NCBIGRCm39mm39
GRCm39 Ensembl290,967,705 - 91,014,182 (-)Ensembl
GRCm38291,137,360 - 91,184,006 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl291,137,360 - 91,183,837 (-)EnsemblGRCm38mm10GRCm38
MGSCv37290,977,517 - 91,024,025 (-)NCBIGRCm37mm9NCBIm37
MGSCv36290,938,200 - 90,984,657 (-)NCBImm8
Celera292,522,135 - 92,568,708 (-)NCBICelera
Cytogenetic Map2E1NCBI
Madd
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955422902,969 - 940,201 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955422902,969 - 940,201 (-)NCBIChiLan1.0ChiLan1.0
MADD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11147,769,863 - 47,829,240 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1147,773,733 - 47,828,360 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01147,216,006 - 47,276,422 (+)NCBIMhudiblu_PPA_v0panPan3
MADD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11842,290,226 - 42,332,237 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1842,290,754 - 42,328,586 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1841,019,254 - 41,060,604 (-)NCBI
ROS_Cfam_1.01842,944,691 - 42,986,383 (-)NCBI
ROS_Cfam_1.0 Ensembl1842,944,691 - 42,986,478 (-)Ensembl
UMICH_Zoey_3.11842,430,983 - 42,472,278 (-)NCBI
UNSW_CanFamBas_1.01841,986,221 - 42,027,872 (-)NCBI
UU_Cfam_GSD_1.01842,715,501 - 42,756,968 (-)NCBI
Madd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494719,779,478 - 19,825,054 (-)NCBI
SpeTri2.0NW_0049365621,891,120 - 1,936,559 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MADD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl215,270,789 - 15,315,477 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1215,270,783 - 15,315,459 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2216,477,477 - 16,538,588 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MADD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1117,987,573 - 18,041,317 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl117,986,860 - 18,042,266 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666038115,287,755 - 115,344,365 (-)NCBIVero_WHO_p1.0
Madd
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247671,421,603 - 1,459,507 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046247671,421,603 - 1,459,738 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
D3Wox32  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2377,115,056 - 77,115,198 (+)MAPPERmRatBN7.2
Rnor_6.0379,960,382 - 79,960,523NCBIRnor6.0
Rnor_5.0386,669,135 - 86,669,276UniSTSRnor5.0
RGSC_v3.4375,498,402 - 75,498,543UniSTSRGSC3.4
Celera376,323,339 - 76,323,480UniSTS
Cytogenetic Map3q24UniSTS
STS-U22662  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2377,158,984 - 77,159,214 (+)MAPPERmRatBN7.2
Rnor_6.0380,004,307 - 80,004,536NCBIRnor6.0
Rnor_5.0386,713,060 - 86,713,289UniSTSRnor5.0
RGSC_v3.4375,542,357 - 75,542,586UniSTSRGSC3.4
Celera376,367,357 - 76,367,586UniSTS
Cytogenetic Map3q24UniSTS
AI548269  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2377,158,931 - 77,159,087 (+)MAPPERmRatBN7.2
Rnor_6.0380,004,254 - 80,004,409NCBIRnor6.0
Rnor_5.0386,713,007 - 86,713,162UniSTSRnor5.0
RGSC_v3.4375,542,304 - 75,542,459UniSTSRGSC3.4
Celera376,367,304 - 76,367,459UniSTS
Cytogenetic Map3q24UniSTS
BE102504  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2377,115,017 - 77,115,192 (+)MAPPERmRatBN7.2
Rnor_6.0379,960,343 - 79,960,517NCBIRnor6.0
Rnor_5.0386,669,096 - 86,669,270UniSTSRnor5.0
RGSC_v3.4375,498,363 - 75,498,537UniSTSRGSC3.4
Celera376,323,300 - 76,323,474UniSTS
Cytogenetic Map3q24UniSTS
RH139546  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2377,157,990 - 77,158,204 (+)MAPPERmRatBN7.2
Rnor_6.0380,003,313 - 80,003,526NCBIRnor6.0
Rnor_5.0386,712,066 - 86,712,279UniSTSRnor5.0
RGSC_v3.4375,541,363 - 75,541,576UniSTSRGSC3.4
Celera376,366,363 - 76,366,576UniSTS
Cytogenetic Map3q24UniSTS
PMC33205P3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2377,159,202 - 77,159,438 (+)MAPPERmRatBN7.2
Rnor_6.0380,004,525 - 80,004,760NCBIRnor6.0
Rnor_5.0386,713,278 - 86,713,513UniSTSRnor5.0
RGSC_v3.4375,542,575 - 75,542,810UniSTSRGSC3.4
Celera376,367,575 - 76,367,810UniSTS
Cytogenetic Map3q24UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)33035677398535386Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)33370334778196190Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)33851780383517803Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)33945463789115240Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)33945463789115240Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)341874578104104347Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)34382736490905114Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)35318469289878207Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)35378111291609953Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)35378111291609953Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35378111291609953Rat
1581568Rf53Renal function QTL 53total urine protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
631200Cm25Cardiac mass QTL 254.80.0001heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)36113434889115068Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)364655305115665732Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)364655305115665732Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)373376539118376539Rat


Genetic Models
This gene Madd is modified in the following models/strains
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:69
Count of miRNA genes:53
Interacting mature miRNAs:67
Transcripts:ENSRNOT00000017360
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 9 2 18 2 74 12 20 9
Low 1 43 48 39 1 39 8 11 23 21 2 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_053585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U72995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000017360   ⟹   ENSRNOP00000017360
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl377,114,976 - 77,157,701 (-)Ensembl
Rnor_6.0 Ensembl379,960,301 - 80,003,032 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000079394   ⟹   ENSRNOP00000075233
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl377,114,976 - 77,157,701 (-)Ensembl
Rnor_6.0 Ensembl379,960,359 - 80,000,091 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000103435   ⟹   ENSRNOP00000084938
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl377,138,063 - 77,157,701 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000104046   ⟹   ENSRNOP00000081884
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl377,114,976 - 77,157,701 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000111515   ⟹   ENSRNOP00000087537
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl377,114,314 - 77,157,701 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000111613   ⟹   ENSRNOP00000076460
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl377,114,314 - 77,157,701 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000112841   ⟹   ENSRNOP00000081476
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl377,114,314 - 77,157,701 (-)Ensembl
RefSeq Acc Id: NM_053585   ⟹   NP_446037
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,976 - 77,157,701 (-)NCBI
Rnor_6.0379,960,301 - 80,003,023 (-)NCBI
Rnor_5.0386,669,054 - 86,711,776 (-)NCBI
RGSC_v3.4375,498,321 - 75,541,073 (-)RGD
Celera376,323,258 - 76,366,073 (-)RGD
Sequence:
RefSeq Acc Id: XM_039106005   ⟹   XP_038961933
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106006   ⟹   XP_038961934
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,115,233 - 77,157,865 (-)NCBI
RefSeq Acc Id: XM_039106007   ⟹   XP_038961935
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,115,233 - 77,157,574 (-)NCBI
RefSeq Acc Id: XM_039106008   ⟹   XP_038961936
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106009   ⟹   XP_038961937
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106010   ⟹   XP_038961938
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106011   ⟹   XP_038961939
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106012   ⟹   XP_038961940
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106014   ⟹   XP_038961942
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106015   ⟹   XP_038961943
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106016   ⟹   XP_038961944
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106017   ⟹   XP_038961945
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106018   ⟹   XP_038961946
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106019   ⟹   XP_038961947
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106020   ⟹   XP_038961948
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106021   ⟹   XP_038961949
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106022   ⟹   XP_038961950
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106023   ⟹   XP_038961951
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106024   ⟹   XP_038961952
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106025   ⟹   XP_038961953
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,115,233 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106026   ⟹   XP_038961954
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106027   ⟹   XP_038961955
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106028   ⟹   XP_038961956
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106029   ⟹   XP_038961957
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106030   ⟹   XP_038961958
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106031   ⟹   XP_038961959
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106032   ⟹   XP_038961960
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106033   ⟹   XP_038961961
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106034   ⟹   XP_038961962
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106035   ⟹   XP_038961963
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106036   ⟹   XP_038961964
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106037   ⟹   XP_038961965
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106038   ⟹   XP_038961966
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106039   ⟹   XP_038961967
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106040   ⟹   XP_038961968
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106041   ⟹   XP_038961969
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106042   ⟹   XP_038961970
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106043   ⟹   XP_038961971
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106044   ⟹   XP_038961972
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106045   ⟹   XP_038961973
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106046   ⟹   XP_038961974
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,154,435 (-)NCBI
RefSeq Acc Id: XM_039106047   ⟹   XP_038961975
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2377,114,330 - 77,147,207 (-)NCBI
Protein Sequences
Protein RefSeqs NP_446037 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961933 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961934 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961935 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961936 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961937 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961938 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961939 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961940 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961942 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961943 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961944 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961945 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961946 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961947 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961948 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961949 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961950 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961951 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961952 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961953 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961954 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961955 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961956 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961957 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961958 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961959 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961960 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961961 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961962 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961963 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961964 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961965 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961966 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961967 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961968 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961969 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961970 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961971 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961972 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961973 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961974 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961975 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC53149 (Get FASTA)   NCBI Sequence Viewer  
  EDL79509 (Get FASTA)   NCBI Sequence Viewer  
  EDL79510 (Get FASTA)   NCBI Sequence Viewer  
  EDL79511 (Get FASTA)   NCBI Sequence Viewer  
  EDL79512 (Get FASTA)   NCBI Sequence Viewer  
  O08873 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_446037   ⟸   NM_053585
- UniProtKB: O08873 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000075233   ⟸   ENSRNOT00000079394
RefSeq Acc Id: ENSRNOP00000017360   ⟸   ENSRNOT00000017360
RefSeq Acc Id: XP_038961961   ⟸   XM_039106033
- Peptide Label: isoform X26
RefSeq Acc Id: XP_038961960   ⟸   XM_039106032
- Peptide Label: isoform X25
RefSeq Acc Id: XP_038961973   ⟸   XM_039106045
- Peptide Label: isoform X38
RefSeq Acc Id: XP_038961955   ⟸   XM_039106027
- Peptide Label: isoform X20
RefSeq Acc Id: XP_038961959   ⟸   XM_039106031
- Peptide Label: isoform X24
RefSeq Acc Id: XP_038961972   ⟸   XM_039106044
- Peptide Label: isoform X37
RefSeq Acc Id: XP_038961974   ⟸   XM_039106046
- Peptide Label: isoform X39
RefSeq Acc Id: XP_038961958   ⟸   XM_039106030
- Peptide Label: isoform X23
RefSeq Acc Id: XP_038961957   ⟸   XM_039106029
- Peptide Label: isoform X22
RefSeq Acc Id: XP_038961971   ⟸   XM_039106043
- Peptide Label: isoform X36
RefSeq Acc Id: XP_038961951   ⟸   XM_039106023
- Peptide Label: isoform X16
RefSeq Acc Id: XP_038961970   ⟸   XM_039106042
- Peptide Label: isoform X35
RefSeq Acc Id: XP_038961950   ⟸   XM_039106022
- Peptide Label: isoform X15
RefSeq Acc Id: XP_038961948   ⟸   XM_039106020
- Peptide Label: isoform X13
RefSeq Acc Id: XP_038961968   ⟸   XM_039106040
- Peptide Label: isoform X33
RefSeq Acc Id: XP_038961947   ⟸   XM_039106019
- Peptide Label: isoform X12
RefSeq Acc Id: XP_038961945   ⟸   XM_039106017
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038961967   ⟸   XM_039106039
- Peptide Label: isoform X32
RefSeq Acc Id: XP_038961943   ⟸   XM_039106015
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038961956   ⟸   XM_039106028
- Peptide Label: isoform X21
RefSeq Acc Id: XP_038961969   ⟸   XM_039106041
- Peptide Label: isoform X34
RefSeq Acc Id: XP_038961949   ⟸   XM_039106021
- Peptide Label: isoform X14
RefSeq Acc Id: XP_038961946   ⟸   XM_039106018
- Peptide Label: isoform X11
RefSeq Acc Id: XP_038961966   ⟸   XM_039106038
- Peptide Label: isoform X31
RefSeq Acc Id: XP_038961942   ⟸   XM_039106014
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038961954   ⟸   XM_039106026
- Peptide Label: isoform X19
RefSeq Acc Id: XP_038961952   ⟸   XM_039106024
- Peptide Label: isoform X17
RefSeq Acc Id: XP_038961965   ⟸   XM_039106037
- Peptide Label: isoform X30
RefSeq Acc Id: XP_038961940   ⟸   XM_039106012
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038961964   ⟸   XM_039106036
- Peptide Label: isoform X29
RefSeq Acc Id: XP_038961939   ⟸   XM_039106011
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038961938   ⟸   XM_039106010
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038961963   ⟸   XM_039106035
- Peptide Label: isoform X28
RefSeq Acc Id: XP_038961936   ⟸   XM_039106008
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038961944   ⟸   XM_039106016
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038961962   ⟸   XM_039106034
- Peptide Label: isoform X27
RefSeq Acc Id: XP_038961937   ⟸   XM_039106009
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038961933   ⟸   XM_039106005
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038961975   ⟸   XM_039106047
- Peptide Label: isoform X40
RefSeq Acc Id: XP_038961934   ⟸   XM_039106006
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038961935   ⟸   XM_039106007
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038961953   ⟸   XM_039106025
- Peptide Label: isoform X18
RefSeq Acc Id: ENSRNOP00000084938   ⟸   ENSRNOT00000103435
RefSeq Acc Id: ENSRNOP00000081884   ⟸   ENSRNOT00000104046
RefSeq Acc Id: ENSRNOP00000087537   ⟸   ENSRNOT00000111515
RefSeq Acc Id: ENSRNOP00000081476   ⟸   ENSRNOT00000112841
RefSeq Acc Id: ENSRNOP00000076460   ⟸   ENSRNOT00000111613
Protein Domains
cDENN   dDENN   Death   uDENN

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O08873-F1-model_v2 AlphaFold O08873 1-1602 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692208
Promoter ID:EPDNEW_R2733
Type:single initiation site
Name:Madd_1
Description:MAP-kinase activating death domain
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0380,003,037 - 80,003,097EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619922 AgrOrtholog
BioCyc Gene G2FUF-48747 BioCyc
Ensembl Genes ENSRNOG00000012568 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000017360 ENTREZGENE
  ENSRNOP00000017360.5 UniProtKB/TrEMBL
  ENSRNOP00000075233 ENTREZGENE
  ENSRNOP00000075233.2 UniProtKB/TrEMBL
  ENSRNOP00000076460 ENTREZGENE
  ENSRNOP00000076460.1 UniProtKB/TrEMBL
  ENSRNOP00000081476 ENTREZGENE
  ENSRNOP00000081476.1 UniProtKB/TrEMBL
  ENSRNOP00000081884 ENTREZGENE
  ENSRNOP00000081884.1 UniProtKB/TrEMBL
  ENSRNOP00000084938.1 UniProtKB/TrEMBL
  ENSRNOP00000087537 ENTREZGENE
  ENSRNOP00000087537.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000017360 ENTREZGENE
  ENSRNOT00000017360.7 UniProtKB/TrEMBL
  ENSRNOT00000079394 ENTREZGENE
  ENSRNOT00000079394.2 UniProtKB/TrEMBL
  ENSRNOT00000103435.1 UniProtKB/TrEMBL
  ENSRNOT00000104046 ENTREZGENE
  ENSRNOT00000104046.1 UniProtKB/TrEMBL
  ENSRNOT00000111515 ENTREZGENE
  ENSRNOT00000111515.1 UniProtKB/TrEMBL
  ENSRNOT00000111613 ENTREZGENE
  ENSRNOT00000111613.1 UniProtKB/TrEMBL
  ENSRNOT00000112841 ENTREZGENE
  ENSRNOT00000112841.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.11500 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro cDENN_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  dDENN_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DENN_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MADD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tripartite_DENN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  uDENN_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:94193 UniProtKB/Swiss-Prot
NCBI Gene 94193 ENTREZGENE
PANTHER PTHR13008 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DENN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  uDENN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Madd PhenoGen
PROSITE DENN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART dDENN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DENN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  uDENN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2KA27_RAT UniProtKB/TrEMBL
  A0A8I5Y5V9_RAT UniProtKB/TrEMBL
  A0A8I5ZSL5_RAT UniProtKB/TrEMBL
  A0A8I5ZTV3_RAT UniProtKB/TrEMBL
  A0A8I6A266_RAT UniProtKB/TrEMBL
  A0A8I6A7E5_RAT UniProtKB/TrEMBL
  A0A8L2Q8M9_RAT UniProtKB/TrEMBL
  MADD_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-02-26 Madd  MAP-kinase activating death domain      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Madd  MAP-kinase activating death domain      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in all tissues, enriched in brain 633238
gene_protein 1,602 amino acids; 178 kDa 633238