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Gene: Ptpmt1 (protein tyrosine phosphatase, mitochondrial 1) Rattus norvegicus
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Symbol: Ptpmt1
Name: protein tyrosine phosphatase, mitochondrial 1
Description: Predicted to have phosphatidylglycerophosphatase activity and phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. Involved in negative regulation of insulin secretion involved in cellular response to glucose stimulus. Localizes to integral component of mitochondrial inner membrane. Orthologous to human PTPMT1 (protein tyrosine phosphatase mitochondrial 1); PARTICIPATES IN cardiolipin biosynthetic pathway; glycerophospholipid metabolic pathway; inositol metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: hypothetical protein LOC29390; LOC29390; phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1; Plip; protein tyrosine phosphatase, mitochondrial 1 (mapped); protein-tyrosine phosphatase mitochondrial 1; PTEN-like phosphatase; Ptpmt1_mapped
Orthologs:
Homo sapiens (human) : PTPMT1 (protein tyrosine phosphatase mitochondrial 1)  HGNC  Alliance
Mus musculus (house mouse) : Ptpmt1 (protein tyrosine phosphatase, mitochondrial 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptpmt1 (protein tyrosine phosphatase mitochondrial 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PTPMT1 (protein tyrosine phosphatase mitochondrial 1)
Canis lupus familiaris (dog) : PTPMT1 (protein tyrosine phosphatase mitochondrial 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptpmt1 (protein tyrosine phosphatase mitochondrial 1)
Sus scrofa (pig) : PTPMT1 (protein tyrosine phosphatase mitochondrial 1)
Chlorocebus sabaeus (African green monkey) : PTPMT1 (protein tyrosine phosphatase mitochondrial 1)
Heterocephalus glaber (naked mole-rat) : Ptpmt1 (protein tyrosine phosphatase mitochondrial 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0379,734,961 - 79,743,737 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl379,734,961 - 79,743,737 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0386,444,081 - 86,452,749 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4375,269,658 - 75,279,872 (-)NCBIRGSC3.4rn4RGSC3.4
Celera376,098,941 - 76,108,482 (-)NCBICelera
Cytogenetic Map3q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Ptpmt1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1589783
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.