Gene: Ptpmt1 (protein tyrosine phosphatase, mitochondrial 1) Rattus norvegicus
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Symbol: Ptpmt1
Name: protein tyrosine phosphatase, mitochondrial 1
Description: ENCODES a protein that exhibits phosphatidylglycerophosphatase activity (ortholog); phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity (ortholog); INVOLVED IN negative regulation of insulin secretion involved in cellular response to glucose stimulus; cardiolipin biosynthetic process (ortholog); regulation of intrinsic apoptotic signaling pathway (ortholog); PARTICIPATES IN cardiolipin biosynthetic pathway; glycerophospholipid metabolic pathway; inositol metabolic pathway; FOUND IN integral component of mitochondrial inner membrane; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene
AGR Description: Predicted to have phosphatidylglycerophosphatase activity and phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; involved in negative regulation of insulin secretion involved in cellular response to glucose stimulus; localizes to the integral component of mitochondrial inner membrane; orthologous to human PTPMT1 (protein tyrosine phosphatase, mitochondrial 1).
Merged Description: Predicted to have phosphatidylglycerophosphatase activity and phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; involved in negative regulation of insulin secretion involved in cellular response to glucose stimulus; localizes to the integral component of mitochondrial inner membrane; orthologous to human PTPMT1 (protein tyrosine phosphatase, mitochondrial 1); PARTICIPATES IN cardiolipin biosynthetic pathway; glycerophospholipid metabolic pathway; inositol metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: hypothetical protein LOC29390; LOC29390; phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1; Plip; protein tyrosine phosphatase, mitochondrial 1 (mapped); protein-tyrosine phosphatase mitochondrial 1; PTEN-like phosphatase; Ptpmt1_mapped
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0379,734,961 - 79,743,737 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0386,444,081 - 86,452,749 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4375,269,658 - 75,279,872 (-)NCBIRGSC3.4rn4RGSC3.4
Celera376,098,941 - 76,108,482 (-)NCBICelera
Cytogenetic Map3q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Ptpmt1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1589783
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.