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Gene: Hsd17b12 (hydroxysteroid (17-beta) dehydrogenase 12) Rattus norvegicus
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Symbol: Hsd17b12
Name: hydroxysteroid (17-beta) dehydrogenase 12
Description: Predicted to have collagen binding activity; fibronectin binding activity; and heparin binding activity. Predicted to be involved in extracellular matrix organization and positive regulation of cell-substrate adhesion. Predicted to localize to the extracellular matrix. Orthologous to human HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12); PARTICIPATES IN steroid hormone biosynthetic pathway; unsaturated fatty acid biosynthetic pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 17-beta-HSD 12; 17-beta-hydroxysteroid dehydrogenase 12; 3-ketoacyl-CoA reductase; estradiol 17-beta-dehydrogenase 12; KAR; LOC84013; smooth muscle-specific 17 beta-hydroxysteroid dehydrogenase type 3; very-long-chain 3-oxoacyl-CoA reductase
Orthologs:
Homo sapiens (human) : HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12)  HGNC  Alliance
Mus musculus (house mouse) : Hsd17b12 (hydroxysteroid (17-beta) dehydrogenase 12)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hsd17b12 (hydroxysteroid 17-beta dehydrogenase 12)
Pan paniscus (bonobo/pygmy chimpanzee) : HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12)
Canis lupus familiaris (dog) : HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hsd17b12 (hydroxysteroid 17-beta dehydrogenase 12)
Sus scrofa (pig) : HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0382,924,699 - 83,048,465 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0389,626,176 - 89,749,541 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4378,436,634 - 78,559,707 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1378,333,061 - 78,456,135 (-)NCBI
Celera379,190,922 - 79,314,232 (-)NCBICelera
Cytogenetic Map3q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Hsd17b12
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 708367
Created: 2003-09-23
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.