Rfk-ps3 (riboflavin kinase, pseudogene 3) - Rat Genome Database

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Gene: Rfk-ps3 (riboflavin kinase, pseudogene 3) Rattus norvegicus
Analyze
Symbol: Rfk-ps3
Name: riboflavin kinase, pseudogene 3
RGD ID: 1560961
Description: Predicted to enable ATP binding activity and riboflavin kinase activity. Predicted to be involved in FMN biosynthetic process and riboflavin biosynthetic process; INTERACTS WITH nefazodone.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC311241; RGD1560961; riboflavin kinase-like; similar to RIKEN cDNA 0610038L10 gene
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83106,965,232 - 106,967,412 (-)NCBIGRCr8
mRatBN7.2386,510,729 - 86,512,353 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl386,511,659 - 86,512,126 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0389,743,733 - 89,745,868 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0396,410,125 - 96,412,295 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4385,344,977 - 85,346,284 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera385,630,517 - 85,632,652 (-)NCBICelera
Cytogenetic Map3q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
nefazodone  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Rfk-ps3
14 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)34382736490905114Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)35318469289878207Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)33945463789115240Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)33945463789115240Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)364655305115665732Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)364655305115665732Rat
7387306Bw124Body weight QTL 1243.20.0003body mass (VT:0001259)body weight (CMO:0000012)384091273129091273Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)373376539118376539Rat
2302273Gluco35Glucose level QTL 355.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)380800231114297550Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35378111291609953Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
631200Cm25Cardiac mass QTL 254.80.0001heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)36113434889115068Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)33035677398535386Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)341874578104104347Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat

Markers in Region
RH129140  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21214,806,001 - 214,806,151 (-)MAPPERmRatBN7.2
mRatBN7.2386,511,414 - 86,511,564 (+)MAPPERmRatBN7.2
Rnor_6.01236,495,462 - 236,495,611NCBIRnor6.0
Rnor_6.0389,744,994 - 89,745,143NCBIRnor6.0
Rnor_5.0396,411,386 - 96,411,535UniSTSRnor5.0
Rnor_5.01243,799,992 - 243,800,141UniSTSRnor5.0
RGSC_v3.41220,930,669 - 220,930,818UniSTSRGSC3.4
RGSC_v3.4385,345,573 - 85,345,722UniSTSRGSC3.4
Celera385,631,778 - 85,631,927UniSTS
Celera1212,121,716 - 212,121,865UniSTS
Cytogenetic Map1q43UniSTS
Cytogenetic Map3q31UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSRNOT00000005784   ⟹   ENSRNOP00000078651
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl386,511,659 - 86,512,126 (-)Ensembl
RefSeq Acc Id: XM_063285285   ⟹   XP_063141355
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83106,965,232 - 106,967,412 (-)NCBI
Protein Sequences
Protein RefSeqs XP_063141355 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000078651.1
RefSeq Acc Id: XP_063141355   ⟸   XM_063285285
- UniProtKB: A0A8I5ZLE0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000078651   ⟸   ENSRNOT00000005784
Protein Domains
Riboflavin kinase

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-48619 BioCyc
Ensembl Genes ENSRNOG00000004381 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000005784.8 UniProtKB/TrEMBL
Gene3D-CATH Riboflavin kinase-like UniProtKB/TrEMBL
InterPro Riboflavin_kinase UniProtKB/TrEMBL
  Riboflavin_kinase_bac/euk UniProtKB/TrEMBL
  Riboflavin_kinase_dom_sf UniProtKB/TrEMBL
NCBI Gene 311241 ENTREZGENE
PANTHER RIBOFLAVIN KINASE UniProtKB/TrEMBL
  RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE UniProtKB/TrEMBL
Pfam Flavokinase UniProtKB/TrEMBL
PhenoGen Rfk-ps3 PhenoGen
RatGTEx ENSRNOG00000004381 RatGTEx
SMART Flavokinase UniProtKB/TrEMBL
Superfamily-SCOP Riboflavin kinase-like UniProtKB/TrEMBL
UniProt A0A8I5ZLE0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-10 Rfk-ps3  riboflavin kinase, pseudogene 3  RGD1560961  similar to RIKEN cDNA 0610038L10 gene  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1560961  similar to RIKEN cDNA 0610038L10 gene   RGD1560961_predicted  similar to RIKEN cDNA 0610038L10 gene (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1560961_predicted  similar to RIKEN cDNA 0610038L10 gene (predicted)  LOC311241  similar to RIKEN cDNA 0610038L10 gene  Symbol and Name status set to approved 1299863 APPROVED