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Gene: Pak6 (p21 (RAC1) activated kinase 6) Rattus norvegicus
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Symbol: Pak6
Name: p21 (RAC1) activated kinase 6
Description: Predicted to have protein serine/threonine kinase activity. Predicted to be involved in several processes, including activation of protein kinase activity; learning or memory; and neuron projection morphogenesis. Predicted to localize to cell junction; cytoplasm; and nuclear lumen. Human ortholog(s) of this gene implicated in clear cell renal cell carcinoma. Orthologous to several human genes including BUB1B-PAK6 (BUB1B-PAK6 readthrough); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; renal cell carcinoma pathway; T cell receptor signaling pathway; INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC296078; p21 (CDKN1A)-activated kinase 6; p21 protein (Cdc42/Rac)-activated kinase 6; p21-activated kinase 6; serine/threonine-protein kinase PAK 6
Orthologs:
Homo sapiens (human) : PAK6 (p21 (RAC1) activated kinase 6)  HGNC  Alliance
Mus musculus (house mouse) : Pak6 (p21 (RAC1) activated kinase 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pak6 (p21 (RAC1) activated kinase 6)
Pan paniscus (bonobo/pygmy chimpanzee) : PAK6 (p21 (RAC1) activated kinase 6)
Canis lupus familiaris (dog) : PAK6 (p21 (RAC1) activated kinase 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101957470 (serine/threonine-protein kinase PAK 6)
Sus scrofa (pig) : PAK6 (p21 (RAC1) activated kinase 6)
Chlorocebus sabaeus (African green monkey) : PAK6 (p21 (RAC1) activated kinase 6)
Heterocephalus glaber (naked mole-rat) : Pak6 (p21 (RAC1) activated kinase 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03110,442,175 - 110,486,317 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3110,442,637 - 110,487,526 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03116,987,226 - 117,027,426 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43105,141,150 - 105,191,676 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13105,080,467 - 105,088,577 (+)NCBI
Celera3104,554,473 - 104,587,411 (+)NCBICelera
Cytogenetic Map3q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Pak6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1306213
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.