Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Nphp1 (nephrocystin 1) Rattus norvegicus
Symbol: Nphp1
Name: nephrocystin 1
RGD ID: 1308136
Description: Predicted to be involved in several processes, including photoreceptor cell outer segment organization; positive regulation of bicellular tight junction assembly; and spermatid differentiation. Predicted to localize to several cellular components, including ciliary base; motile cilium; and photoreceptor distal connecting cilium. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome; Joubert syndrome 4; Senior-Loken syndrome; nephronophthisis; and nephronophthisis 1. Orthologous to human NPHP1 (nephrocystin 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: hypothetical protein LOC680233; LOC296136; LOC680233; nephrocystin-1; nephronophthisis 1 (juvenile); nephronophthisis 1 (juvenile) homolog; nephronophthisis 1 (juvenile) homolog (human)
Homo sapiens (human) : NPHP1 (nephrocystin 1)  HGNC  Alliance
Mus musculus (house mouse) : Nphp1 (nephronophthisis 1 (juvenile) homolog (human))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nphp1 (nephrocystin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NPHP1 (nephrocystin 1)
Canis lupus familiaris (dog) : NPHP1 (nephrocystin 1)
Sus scrofa (pig) : NPHP1 (nephrocystin 1)
Chlorocebus sabaeus (African green monkey) : NPHP1 (nephrocystin 1)
Heterocephalus glaber (naked mole-rat) : Nphp1 (nephrocystin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03120,316,048 - 120,370,089 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3120,316,047 - 120,373,500 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03126,960,471 - 127,017,986 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43115,263,821 - 115,322,901 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13115,169,392 - 115,225,028 (-)NCBI
Celera3113,795,120 - 113,850,690 (-)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Nphp1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308136
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.