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Gene: Prr5l (proline rich 5 like) Rattus norvegicus

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Symbol:

Prr5l

Name:

proline rich 5 like

RGD ID:

1309969

Description:

Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including TORC2 signaling; regulation of fibroblast migration; and regulation of primary metabolic process. Predicted to act upstream of or within positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction and positive regulation of protein phosphorylation. Predicted to be part of TORC2 complex. Orthologous to human PRR5L (proline rich 5 like); PARTICIPATES IN mTOR signaling pathway; INTERACTS WITH 6-propyl-2-thiouracil; bis(2-chloroethyl) sulfide; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC362171; proline-rich protein 5-like; protein observed with Rictor-2; Protor-2; Protor2; RGD1309969; similar to RIKEN cDNA 2600010E01

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PRR5L (proline rich 5 like)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Prr5l (proline rich 5 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Prr5l (proline rich 5 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PRR5L (proline rich 5 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PRR5L (proline rich 5 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Prr5l (proline rich 5 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PRR5L (proline rich 5 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PRR5L (proline rich 5 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Prr5l (proline rich 5 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Prr5l (proline rich 5 like)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	PRR5L (proline rich 5 like)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-147k10.5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	prr5l	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Allele / Splice:

Prr5l^{Tn(sb-T2/Bart3)2.228Mcwi}

Genetic Models:

F344-Prr5l^{Tn(sb-T2/Bart3)2.228Mcwi}

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	108,458,107 - 108,628,552 (-)	NCBI		GRCr8
mRatBN7.2	3	88,001,951 - 88,173,532 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	88,003,617 - 88,082,763 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	91,497,849 - 91,579,208 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	100,096,877 - 100,178,236 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	97,925,761 - 98,004,913 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	91,290,207 - 91,461,208 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	91,291,875 - 91,370,167 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	97,950,297 - 98,119,477 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	86,868,129 - 86,948,468 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	86,764,033 - 86,844,895 (-)	NCBI
Celera	3	87,111,242 - 87,189,435 (-)	NCBI		Celera
Cytogenetic Map	3	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

intellectual disability (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1-dichloroethene (ISO)

1,2-dichloroethane (ISO)

17beta-estradiol (ISO)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

acrolein (ISO)

aflatoxin B1 (ISO)

alpha-pinene (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bis(2-chloroethyl) sulfide (EXP)

bisphenol A (EXP,ISO)

butan-1-ol (ISO)

butanal (ISO)

calcitriol (ISO)

cannabidiol (ISO)

carbon nanotube (ISO)

chloroprene (ISO)

chlorpyrifos (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

clothianidin (ISO)

coumarin (ISO)

Cuprizon (EXP)

DDE (ISO)

deoxynivalenol (ISO)

Dibutyl phosphate (ISO)

diethylstilbestrol (ISO)

dimethylarsinic acid (ISO)

dioxygen (EXP,ISO)

diuron (EXP)

dorsomorphin (ISO)

endosulfan (EXP)

folic acid (ISO)

genistein (ISO)

lipopolysaccharide (ISO)

methamphetamine (EXP)

methapyrilene (ISO)

methotrexate (ISO)

methoxychlor (EXP)

methylarsonic acid (ISO)

N-Nitrosopyrrolidine (ISO)

nickel atom (ISO)

O-methyleugenol (ISO)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

paraquat (EXP)

Rutecarpine (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sotorasib (ISO)

sulforaphane (ISO)

temozolomide (ISO)

tetraphene (ISO)

thimerosal (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

topotecan (EXP)

trametinib (ISO)

trichostatin A (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

valproic acid (ISO)

vorinostat (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

cellular response to oxidative stress (IEA,ISO,ISS)

negative regulation of protein phosphorylation (ISO,ISS)

negative regulation of signal transduction (IEA)

phosphatidylinositol 3-kinase/protein kinase B signal transduction (IEA,ISO)

positive regulation of intracellular protein transport (IEA,ISO,ISS)

positive regulation of mRNA catabolic process (IEA,ISO,ISS)

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (IEA,ISO)

positive regulation of protein phosphorylation (ISO)

protein phosphorylation (ISO)

regulation of fibroblast migration (IEA,ISO,ISS)

TORC2 signaling (IBA,IEA,ISO,ISS)

Cellular Component

TORC2 complex (IBA,IEA,ISO,ISS)

Molecular Function

protein binding (ISO)

ubiquitin protein ligase binding (IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

mTOR signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	mTOR signaling in growth control and disease.	Laplante M and Sabatini DM, Cell. 2012 Apr 13;149(2):274-93. doi: 10.1016/j.cell.2012.03.017.
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:12477932	PMID:15489334	PMID:18614015	PMID:21413931	PMID:21964062	PMID:22609986

Genomics

Comparative Map Data

Prr5l
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	108,458,107 - 108,628,552 (-)	NCBI		GRCr8
mRatBN7.2	3	88,001,951 - 88,173,532 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	88,003,617 - 88,082,763 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	91,497,849 - 91,579,208 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	100,096,877 - 100,178,236 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	97,925,761 - 98,004,913 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	91,290,207 - 91,461,208 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	91,291,875 - 91,370,167 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	97,950,297 - 98,119,477 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	86,868,129 - 86,948,468 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	86,764,033 - 86,844,895 (-)	NCBI
Celera	3	87,111,242 - 87,189,435 (-)	NCBI		Celera
Cytogenetic Map	3	q31	NCBI

PRR5L
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	36,296,288 - 36,465,204 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	36,296,288 - 36,465,204 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	36,317,838 - 36,486,754 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	36,354,131 - 36,443,330 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	11	36,466,181 - 36,637,921 (+)	NCBI		Celera
Cytogenetic Map	11	p13-p12	NCBI
HuRef	11	36,017,351 - 36,188,822 (+)	NCBI		HuRef
CHM1_1	11	36,315,873 - 36,485,532 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	36,436,630 - 36,607,651 (+)	NCBI		T2T-CHM13v2.0

Prr5l
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	101,543,455 - 101,713,428 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	101,544,630 - 101,713,372 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	101,713,110 - 101,883,052 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	101,714,285 - 101,883,027 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	101,554,442 - 101,679,137 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	101,517,087 - 101,598,456 (-)	NCBI		MGSCv36	mm8
MGSCv36	2	102,525,319 - 102,608,002 (-)	NCBI		MGSCv36	mm8
Celera	2	102,939,329 - 103,063,664 (-)	NCBI		Celera
Cytogenetic Map	2	E2	NCBI
cM Map	2	53.93	NCBI

Prr5l
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	9,972,588 - 10,048,669 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955422	9,972,588 - 10,069,411 (-)	NCBI	ChiLan1.0	ChiLan1.0

PRR5L
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	38,517,112 - 38,686,799 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	38,521,756 - 38,691,440 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	36,269,291 - 36,438,954 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	36,143,905 - 36,311,659 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	36,223,385 - 36,311,659 (+)	Ensembl	panpan1.1		panPan2

PRR5L
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	31,708,888 - 31,849,365 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	31,706,546 - 31,849,491 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	31,313,676 - 31,455,863 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	32,316,310 - 32,459,199 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	32,317,883 - 32,387,382 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	31,886,211 - 32,028,310 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	31,472,745 - 31,613,238 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	32,108,514 - 32,250,549 (-)	NCBI		UU_Cfam_GSD_1.0

Prr5l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	28,770,806 - 28,922,834 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936533	1,895,380 - 1,975,824 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936533	1,895,594 - 1,975,442 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PRR5L
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	24,646,871 - 24,812,610 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	24,646,865 - 24,812,642 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	26,811,301 - 26,949,585 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PRR5L
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	28,771,858 - 28,951,201 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	28,771,793 - 28,841,572 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	125,912,249 - 126,006,339 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Prr5l
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624767	10,781,954 - 10,950,243 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624767	10,781,954 - 10,950,142 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Prr5l
1513 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	540
Count of miRNA genes:	240
Interacting mature miRNAs:	285
Transcripts:	ENSRNOT00000006291
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300178	Hrtrt4	Heart rate QTL 4	3.74		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	43827364	90905114	Rat
61377	Edpm3	Estrogen-dependent pituitary mass QTL 3	7.05	0.038	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	53184692	89878207	Rat
2301414	Kidm37	Kidney mass QTL 37		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	70653097	121056321	Rat
1582238	Bw68	Body weight QTL 68	3.2	0.0064	body mass (VT:0001259)	body weight (CMO:0000012)	3	53184593	115665732	Rat
1331795	Rf30	Renal function QTL 30	3.708		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	3	39454637	89115240	Rat
1582239	Epfw1	Epididymal fat weight QTL 1	4.5	0.0006	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	3	53184593	115665732	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	31172320	163586636	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	47233211	147415807	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	38192233	133483320	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	29463235	118376539	Rat
1582218	Bw74	Body weight QTL 74	3.9	0.0021	body mass (VT:0001259)	body weight (CMO:0000012)	3	53184593	115665732	Rat
1331777	Bw24	Body weight QTL 24	3.503		body mass (VT:0001259)	body weight (CMO:0000012)	3	39454637	89115240	Rat
1582221	Kidm30	Kidney mass QTL 30	3.5	0.0008	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	3	64655305	115665732	Rat
1581568	Rf53	Renal function QTL 53			urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	3	56395968	161299569	Rat
1582210	Bw71	Body weight QTL 71	3.3	0.0012	body mass (VT:0001259)	body weight (CMO:0000012)	3	64655305	115665732	Rat
7387306	Bw124	Body weight QTL 124	3.2	0.0003	body mass (VT:0001259)	body weight (CMO:0000012)	3	84091273	129091273	Rat
1300111	Rf12	Renal function QTL 12	3.78		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	61017749	121056321	Rat
724523	Tsu1	Thymus enlargement suppressive QTL 1	3.84		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	3	50437504	115638231	Rat
1600376	Arunc5	Aerobic running capacity QTL 5		0.21	exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	3	73376539	118376539	Rat
2302273	Gluco35	Glucose level QTL 35	5.3	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	80800231	114297550	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	59242096	157323038	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	43827364	169034231	Rat
1581503	Cm58	Cardiac mass QTL 58	2.7	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	43827364	121056321	Rat
2292613	Ept16	Estrogen-induced pituitary tumorigenesis QTL 16	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	47233430	110362260	Rat
731180	Bp152	Blood pressure QTL 152		0.03	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	53781112	91609953	Rat
631200	Cm25	Cardiac mass QTL 25	4.8	0.0001	heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	3	61134348	89115068	Rat
61419	Cia11	Collagen induced arthritis QTL 11	5.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	3	30356773	98535386	Rat
12879848	Bw181	Body weght QTL 181		0.015	body mass (VT:0001259)	body weight (CMO:0000012)	3	70348525	121056321	Rat
1358905	Hrtrt17	Heart rate QTL 17	5.9	0.000014	heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	10861912	89878372	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	41874578	155617519	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
1354597	Kidm13	Kidney mass QTL 13	2.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	3	41874578	104104347	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	41874578	155617519	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	78196190	146592722	Rat
2290452	Scl56	Serum cholesterol level QTL 56	2.26		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	3	1	91609953	Rat
1354604	Bw36	Body weight QTL 36	2.9		body mass (VT:0001259)	body weight (CMO:0000012)	3	33703347	104104347	Rat
631665	Bw8	Body weight QTL 8	5.5		body mass (VT:0001259)	body weight (CMO:0000012)	3	50437042	119183768	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
1358186	Ept2	Estrogen-induced pituitary tumorigenesis QTL 2	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	47233430	110362260	Rat

Markers in Region

D3Rat76

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	3	108,511,961 - 108,512,164 (+)	Marker Load Pipeline
mRatBN7.2	3	88,056,951 - 88,057,154 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	91,344,449 - 91,344,651	NCBI	Rnor6.0
Rnor_5.0	3	98,003,200 - 98,003,402	UniSTS	Rnor5.0
RGSC_v3.4	3	86,920,826 - 86,921,029	RGD	RGSC3.4
RGSC_v3.4	3	86,920,827 - 86,921,029	UniSTS	RGSC3.4
RGSC_v3.1	3	86,817,255 - 86,817,457	RGD
Celera	3	87,163,691 - 87,163,893	UniSTS
RH 3.4 Map	3	671.1	UniSTS
RH 3.4 Map	3	671.1	RGD
RH 2.0 Map	3	451.7	RGD
SHRSP x BN Map	3	46.7498	RGD
Cytogenetic Map	3	q31	UniSTS

D3Rat265

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	3	108,492,087 - 108,492,277 (+)	Marker Load Pipeline
mRatBN7.2	3	88,037,073 - 88,037,263 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	91,325,598 - 91,325,787	NCBI	Rnor6.0
Rnor_5.0	3	97,984,349 - 97,984,538	UniSTS	Rnor5.0
RGSC_v3.4	3	86,900,972 - 86,901,162	RGD	RGSC3.4
RGSC_v3.4	3	86,900,973 - 86,901,162	UniSTS	RGSC3.4
RGSC_v3.1	3	86,797,401 - 86,797,590	RGD
Celera	3	87,143,814 - 87,144,003	UniSTS
RH 3.4 Map	3	676.0	UniSTS
RH 3.4 Map	3	676.0	RGD
RH 2.0 Map	3	455.2	RGD
SHRSP x BN Map	3	46.1498	RGD
Cytogenetic Map	3	q31	UniSTS

D3Got38

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	88,044,983 - 88,045,243 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	91,333,504 - 91,333,763	NCBI	Rnor6.0
Rnor_6.0	3	91,145,834 - 91,146,093	NCBI	Rnor6.0
Rnor_5.0	3	97,992,255 - 97,992,514	UniSTS	Rnor5.0
Rnor_5.0	3	97,805,848 - 97,806,107	UniSTS	Rnor5.0
RGSC_v3.4	3	86,908,881 - 86,909,141	RGD	RGSC3.4
RGSC_v3.4	3	86,908,882 - 86,909,141	UniSTS	RGSC3.4
RGSC_v3.1	3	86,805,310 - 86,805,569	RGD
Celera	3	87,151,720 - 87,151,979	UniSTS
RH 3.4 Map	3	669.9	UniSTS
RH 3.4 Map	3	669.9	RGD
RH 2.0 Map	3	459.3	RGD
Cytogenetic Map	3	q31	UniSTS

BE110692

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	88,058,343 - 88,058,498 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	91,345,841 - 91,345,995	NCBI	Rnor6.0
Rnor_5.0	3	98,004,592 - 98,004,746	UniSTS	Rnor5.0
RGSC_v3.4	3	86,922,219 - 86,922,373	UniSTS	RGSC3.4
Celera	3	87,165,083 - 87,165,237	UniSTS
RH 3.4 Map	3	678.0	UniSTS
Cytogenetic Map	3	q31	UniSTS

Genetic Models

This gene Prr5l is modified in the following models/strains:

F344-Prr5l^{Tn(sb-T2/Bart3)2.228Mcwi}

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001080150	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006234647	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006234648	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017591900	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105436	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AY724495	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC129104	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000006291 ⟹ ENSRNOP00000006291

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	88,003,617 - 88,082,763 (-)	Ensembl
Rnor_6.0 Ensembl	3	91,291,875 - 91,370,167 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000114001 ⟹ ENSRNOP00000078961

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	88,003,617 - 88,082,763 (-)	Ensembl

RefSeq Acc Id:

NM_001080150 ⟹ NP_001073619

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	108,458,630 - 108,537,763 (-)	NCBI
mRatBN7.2	3	88,003,614 - 88,082,763 (-)	NCBI
Rnor_6.0	3	91,291,870 - 91,370,167 (-)	NCBI
Rnor_5.0	3	97,950,297 - 98,119,477 (-)	NCBI
RGSC_v3.4	3	86,868,129 - 86,948,468 (-)	RGD
Celera	3	87,111,242 - 87,189,435 (-)	RGD

Sequence:

show sequence

CGCTGAAGAGAAACCTGAGCAGGACACGACCCAGCGGAGGGCAGAGGTGGGAGAGGACCTCGGG
AGGGCGAGCGAGGCAAGAACAATCCAAAATCGCTGGTTTCTCTCCAGCGAGAAAACTTTCCTTG
GGACGACGGAAACTTTTTTCCTGCGCGCGCAGAGTCTGGGACAGAGGCGAGCGGCGGGTGTACG
CGGCTCCGCTCCTGTGACTCACGCCCGGGACCCCAAGGGGGTGCTGGCTGACAGTAGGGTTTTA
AGACACCCCAGAAGCAGCGTTGAGGGAAGCCTTTCTTTCCTGTGGGTGGCCAGAAGCTTCTGGT
CCTCAAGACACAGCTCAATCCTCACCTGGACTTATGACCCGCGGCCTTGCTCCCCTCCTGCCCA
TTGAGTTCCACAAGATGGGCTCCTTCCGCCGGCCTAGACCACGATTTATGAGCTCCCCTCTGCT
CAGCGAGCTGCCCCGCTTTCAGGCTGCCCGGCAGGCTCTGCAACTAAGTTCCAACTCAGCCTGG
AACAGTGTGCAGACGGCTGTGATCAACGTTTTCAAAGGGGGCGGCTTGCAGAGCAATGAGCTGT
ATGCACTGAACGAAAGCATCAGGCGGCTGCTGAAGAGTGAACTTGGATCGTTCATTACTGACTA
CTTCCAGAACCAGCTTCTTGCAAAAGGACTGTCCTTTGTGGAGGAGAAGATCAAGCAGTGTGAA
GGTGACAATCGCATTGAGGTTCTGGCTGAAGTCTGGGACCACTTCTTCACCGAGACACTCCCTA
CCCTGCAGGCAATATTTTATCCGGTTCAGGGACAGGAGCTGACCATCCGCCAGATCTCCCTGCT
GGGCTTCCGGGACCTGGTCTTGCTGAAGGTGAAGCTGGGTGACTTGCTGCTGTTGTCACAGTCC
AAGTTGCCTTCTTCTGTTATACAGATGCTTCTCATTCTGCAGAGTGTTCACGAGCCCACAGGCC
CAAGTGAGGGCTATTTGCAGCTGGAGGAGCTGGTGAAGCAAGTGGTGTCTCCCTTCCTCGGCCT
CAGCGGGGACCGCAGCTGCTCACGCCCCACACACTCACTGGCCAGGAGGCATTCCAGGGTCCGG
CCCAAGGTGACCGTCCTGAACTATGCCTCTCTGATGACCACGGTTGGCCGGCCACTGAATGAGA
TGGTCTTGACCCCTCTAACAGAACAGGAAGGAGAGGCATACCTGGAGAAGTGTGGCAGCGTCCG
GCGGCACACAGTGGCCAATGCCCACTCGGACATCCAGCTGCTGGCTATGGCCACCATGATGCAC
TCAGGGTTGGGGGAGGAGTCTGGAAGCGAGGACAAACACCTGCTCCTGCCACCCACCTTCCCAC
CACCACACCGCCAATGCTCCAGTGAGCCCAGCATCCTTGATAGTCCTGATGAAATGGAACTGGA
AGATGTAGCAAGTGGCAGCCAAGAGGACTCAGAGCTGAATTGTGCTTCCCTCAGCTGAGCCACC
ACCTCCAGGGACCCATTCCTACTTTGAGGCTAGGATGAGGACACCCTTCCTCCTCCACGGATCA
CCCAGGGGCTCTTGCATTGGGCAATATTGCCTTACTTCCTTTAGGGCACAAGTCAAGTCTCCAC
GCCCTTGGGAAACACCTGTTGACCTCCCAACTCTGGTGTCTGTGACCAGCTCCTCATGCCACCG
TTGTTCTGACTTCCAGCCTTGCCTCATTCACCTGGATCCTCATCCCTGGGCCTTCCGCATCCTA
TTGGACTGACTGGTACTCCTGGGATATAATGCTCTGGCATTATTTTTATAGCAGAAGGTTGGGC
TACTACACACGAGCTTCTGAAGTGTGCCAATCTCTGTAGTTTCTGTTATGATCTTATGAGGCAG
AAGCCAACGGGTGGAAAAAACAGTAAAGATTCTGTGTAGCATGGAAATCAGCTGCAGCCCGTAT
CGTACATGGTACTGGGAATGTGGCCTCATCACTTTAATTGCAGAGTTACTGGGAAACCATTTTC
CCACTTGTGGGCGAAGATTCATTCTTAGGAATGTCCAGATATCATGTTCTGTCTACATCATGGA
CTTTGGCCTAGGAGAACGTATTAGACTGGCACGGCCCTGTCTTGCATTAAGCCTCTCAGCCTGT
CTGTCTCAGGCTTCCTCTCAGACTCTGGGAATGAACCTTCTCAGTCACTGGTGCCTTACTCTTT
CTCCAGTTTCAGGAACTGACCACTTTTCTGTTGTGTATACGAGAGGCTGCTGACAGAAGCTGAT
GTAGACTGTACCTGGATTTCACTTGAATTTGTAAAATGTGTATTGCTCAAAAAAAATGTTTGCA
AATATTTGCACATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006234647 ⟹ XP_006234709

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	108,458,107 - 108,538,020 (-)	NCBI
mRatBN7.2	3	88,001,951 - 88,083,012 (-)	NCBI
Rnor_6.0	3	91,290,207 - 91,370,435 (-)	NCBI
Rnor_5.0	3	97,950,297 - 98,119,477 (-)	NCBI

Sequence:

show sequence

ACTTCCCTTGATTTGCAGCATCCTCCCCTGCTTTTTAGGACCACGAGCTTGGATTTCCTGAAAT
TGTTGAAGTGGATTTAAGCGCAGGTCTTCCGTCTCCTCTTGTTGTTGGAGAGGAGGCGTAGGAT
GGGGTGAAGCGAAGCGGGGGCGTTGGAGAGAAACCACAGCGATGTGCACCGGACAGGAAAAGTG
GGAGGAGGAGGGGGAGGAGGAGAGGAGGCGGCCGTAAGTTGAGAGAGGAGGGAAACAGTCACCA
GCCTGAGAGCTACGCTGAAGAGAAACCTGAGCAGGACACGACCCAGCGGAGGGCAGAGGTGGGA
GAGGACCTCGGGAGGGCGAGCGAGGCAAGAACAATCCAAAATCGCTGGTTTCTCTCCAGCGAGA
AAACTTTCCTTGGGACGACGGAAACTTTTTTCCTGCGCGCGCAGAGTCTGGGACAGAGGCGAGC
GGCGGGTGTACGCGGCTCCGCTCCTGTGACTCACGCCCGGGACCCCAAGGGGGTGAGTGGGGAA
GTCCCTGGAGGGCCTGGAGTCATCCTTCTGCAACTCCTCAGACTCGGAAAATAACTCTCCTGGC
GTGATCTGGGGGTGGGAGTGGGAGCACCGGAGACAGCGAGACTGAGGGGAGACTCCGCGTGGTT
AAGGAACCTCCGCATCGGATGCTGTAGGCGGGGAGGTAGACTACCAAGAGGTGCTGGCTGACAG
TAGGGTTTTAAGACACCCCAGAAGCAGCGTTGAGGGAAGCCTTTCTTTCCTGTGGGTGGCCAGA
AGCTTCTGGTCCTCAAGACACAGCTCAATCCTCACCTGGACTTATGACCCGCGGCCTTGCTCCC
CTCCTGCCCATTGAGTTCCACAAGATGGGCTCCTTCCGCCGGCCTAGACCACGATTTATGAGCT
CCCCTGTGCTCAGCGAGCTGCCCCGCTTTCAGGCTGCCCGGCAGGCTCTGCAACTAAGTTCCAA
CTCAGCCTGGAACAGTGTGCAGACGGCTGTGATCAACGTTTTCAAAGGGGGCGGCTTGCAGAGC
AATGAGCTGTATGCACTGAACGAAAGCATCAGGCGGCTGCTGAAGAGTGAACTTGGATCGTTCA
TTACTGACTACTTCCAGAACCAGCTTCTTGCAAAAGGACTGTCCTTTGTGGAGGAGAAGATCAA
GCAGTGTGAAGGTGACAATCGCATTGAGGTTCTGGCTGAAGTCTGGGACCACTTCTTCACCGAG
ACACTCCCTACCCTGCAGGCAATATTTTATCCGGTTCAGGGACAGGAGCTGACCATCCGCCAGA
TCTCCCTGCTGGGCTTCCGGGACCTGGTCTTGCTGAAGGTGAAGCTGGGTGACTTGCTGCTGTT
GTCACAGTCCAAGTTGCCTTCTTCTGTTATACAGATGCTTCTCATTCTGCAGAGTGTTCACGAG
CCCACAGGCCCAAGTGAGGGCTATTTGCAGCTGGAGGAGCTGGTGAAGCAAGTGGTGTCTCCCT
TCCTCGGCCTCAGCGGGGACCGCAGCTGCTCACGCCCCACACACTCACTGGCCAGGAGGCATTC
CAGGGTCCGGCCCAAGGTGACCGTCCTGAACTATGCCTCTCTGATGACCACGGTTGGCCGGCCA
CTGAATGAGATGGTCTTGACCCCTCTAACAGAACAGGAAGGAGAGGCATACCTGGAGAAGTGTG
GCAGCGTCCGGCGGCACACAGTGGCCAATGCCCACTCGGACATCCAGCTGCTGGCTATGGCCAC
CATGATGCACTCAGGGTTGGGGGAGGAGTCTGGAAGCGAGGACAAACACCTGCTCCTGCCACCC
ACCTTCCCACCACCACACCGCCAATGCTCCAGTGAGCCCAGCATCCTTGATAGTCCTGATGAAA
TGGAACTGGAAGATGTAGCAAGTGGCAGCCAAGAGGACTCAGAGCTGAATTGTGCTTCCCTCAG
CTGAGCCACCACCTCCAGGGACCCATTCCTACTTTGAGGCTAGGATGAGGACACCCTTCCTCCT
CCACGGATCACCCAGGGGCTCTTGCATTGGGCAATATTGCCTTACTTCCTTTAGGGCACAAGTC
AAGTCTCCACGCCCTTGGGAAACACCTGTTGACCTCCCAACTCTGGTGTCTGTGACCAGCTCCT
CATGCCACCGTTGTTCTGACTTCCAGCCTTGCCTCATTCACCTGGATCCTCATCCCTGGGCCTT
CCGCATCCTATTGGACTGACTGGTACTCCTGGGATATAATGCTCTGGCATTATTTTTATAGCAG
AAGGTTGGGCTACTACACACGAGCTTCTGAAGTGTGCCAATCTCTGTAGTTTCTGTTATGATCT
TATGAGGCAGAAGCCAACGGGTGGAAAAAACAGTAAAGATTCTGTGTAGCATGGAAATCAGCTG
CAGCCCGTATCGTACATGGTACTGGGAATGTGGCCTCATCACTTTAATTGCAGAGTTACTGGGA
AACCATTTTCCCACTTGTGGGCGAAGATTCATTCTTAGGAATGTCCAGATATCATGTTCTGTCT
ACATCATGGACTTTGGCCTAGGAGAACGTATTAGACTGGCACGGCCCTGTCTTGCATTAAGCCT
CTCAGCCTGTCTGTCTCAGGCTTCCTCTCAGACTCTGGGAATGAACCTTCTCAGTCACTGGTGC
CTTACTCTTTCTCCAGTTTCAGGAACTGACCACTTTTCTGTTGTGTATACGAGAGGCTGCTGAC
AGAAGCTGATGTAGACTGTACCTGGATTTCACTTGAATTTGTAAAATGTGTATTGCTCAAAAAA
AATGTTTGCAAATATTTGCACATAGGGTCTTGCACTGCTCATTTCCAGTGGAGTGTGTTTGCAC
ACTAAACACAGGTGGACCCCTTCAAAAGGCGGTGGAATCGCTCAGAACAAAAGGATCAGTAGTA
GGTAGGACTCTCATACCTCAGAGCTCTAGAGGAGCCAGAACTGTGTCTGGAATGGCCTGTGTTG
TGAGTGTCTTGGCTTCTAGGGAAGGCTGTGCTGGGGTCAGGAAACTGCCTCTTCAGCAGGGGAG
TGTCGTGGCTGGACTGTATTTGCTTTACATCAGACAGGGAGAGATAGGGACGTGGACACGTTTT
ACTTGCTCCCTGAGATAACAGAAGTACCCAGAAGTCTCTGGAATCCCTGTCACATCTGCTTCGT
GTTGCTATTTGAGGCAGCAGACTTTATTTCTATGCTAGGTCCTCACTACTGCTCCCTTCAGGCT
GGGGAAAGGGAACATTTTGTCTCCATTGAGACATGCTCAGATAATTATCTGTTGATCTTGCTAA
TAGAAACTCAGAAAAATATAGACATTTTCTCCTGACCCTGTTTGTGGTATGTGCTGGCACTTTA
AGCTCTTCTAAGCTTCAATGGTGTCTCCCTTCTGGGCAAAGATCTGAAATATGACTATAGCCGG
GCTATTAATGGATTCTGCTTTAGAAGTTGCATTTTAAAAAGTGTTTTAATTTTGTCCTTCCAAG
AGATAATGACGAAAGAGAAATGTCTTCATGTGTGCACACACCCTGGTCCTGCACTTGCATATAC
ACACTTATACCCATACATGTGCACACACACACACTCCACATATGCAGAAAGAAATGTTCAGATT
CCTTTGAGAGCTTCAATCAAGTAATCTCTCTGTATGTGCTGTCTGAAGTCTACAGATTGGAGCT
GGAGAAGTGGCTTGGTGCTCAAGATCACTTGCTGCTCTTGCAGGAGGCCCAAGATGTGATTTAG
TTCCTACAACATCAGGCGGCTCACAACCACATGCCTATAACTCTAGTCCTAGAGGTTCTGATGC
TCTCTTCTGTCGTCCTAGGGCGTCTGAGTGTACACGCACACATGCACATGCGCGCGCGCGCACA
CACACACACACACACACACACATACACACACACACACACACACACACCACAAGCTGTTAACATA
TGTTAGTAGGCAGAACATTGCAGTTTGTTTAACCGATGGCTAGGTTCTTGTTACTACGCCAATC
ACACACTTGAGATTATTTATTGATCAAGGCAAAGCAATTAGTCATGTTTGGGTTTGCTTTTTTT
GTTGATAAGATTGACAACGCATGCTTTTTAAATGCCTTTTCCCCTTATTTTCGATGTCTCTGTC
GGGACGGAAGTTGTCAGCTAAAGACATGAGCTGTTGTATTGAAAGTGTACAGGCTGTAGACCTT
CATTGCTGCTGACTTCACACAGTTTACAGGATTCTCGTGGACACACCAGGTATTATTACAGAAA
TATCCCAGATCATGCACATAAACATTTTATGGGTGCAAGAGTGTCACCTGTAGGAGTTTTAACC
AAACTCCACTCCCCTGGTACCATGGAGACTCATCTTACTATTTAGTTTAGTGACAGGAAATAAT
CCCAGCTCTGGGCTCTGCTGGAACTCACAAATTCTTTCTGGTTGTCTGTTTTCAAAATAGATAG
AATAAACATTGTTATGCCGTGGA

hide sequence

RefSeq Acc Id:

XM_017591900 ⟹ XP_017447389

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	108,458,107 - 108,628,552 (-)	NCBI
mRatBN7.2	3	88,001,951 - 88,173,532 (-)	NCBI
Rnor_6.0	3	91,290,207 - 91,461,208 (-)	NCBI

Sequence:

show sequence

TCCTGCTGGTAGAGGCGGCCTTTCAGATTCTGTTTTCGTTCCCATTAGTTTTCAGAGTCAGTGA
GTGGTGAGTGGGGCCTACTGTCAAAGTGTCACCACCTCAGAAGGCTGGAAGGACAGGACACTTC
ACCTCTCCTGGGAAAGGTGCTGGCTGACAGTAGGGTTTTAAGACACCCCAGAAGCAGCGTTGAG
GGAAGCCTTTCTTTCCTGTGGGTGGCCAGAAGCTTCTGGTCCTCAAGACACAGCTCAATCCTCA
CCTGGACTTATGACCCGCGGCCTTGCTCCCCTCCTGCCCATTGAGTTCCACAAGATGGGCTCCT
TCCGCCGGCCTAGACCACGATTTATGAGCTCCCCTGTGCTCAGCGAGCTGCCCCGCTTTCAGGC
TGCCCGGCAGGCTCTGCAACTAAGTTCCAACTCAGCCTGGAACAGTGTGCAGACGGCTGTGATC
AACGTTTTCAAAGGGGGCGGCTTGCAGAGCAATGAGCTGTATGCACTGAACGAAAGCATCAGGC
GGCTGCTGAAGAGTGAACTTGGATCGTTCATTACTGACTACTTCCAGAACCAGCTTCTTGCAAA
AGGACTGTCCTTTGTGGAGGAGAAGATCAAGCAGTGTGAAGGTGACAATCGCATTGAGGTTCTG
GCTGAAGTCTGGGACCACTTCTTCACCGAGACACTCCCTACCCTGCAGGCAATATTTTATCCGG
TTCAGGGACAGGAGCTGACCATCCGCCAGATCTCCCTGCTGGGCTTCCGGGACCTGGTCTTGCT
GAAGGTGAAGCTGGGTGACTTGCTGCTGTTGTCACAGTCCAAGTTGCCTTCTTCTGTTATACAG
ATGCTTCTCATTCTGCAGAGTGTTCACGAGCCCACAGGCCCAAGTGAGGGCTATTTGCAGCTGG
AGGAGCTGGTGAAGCAAGTGGTGTCTCCCTTCCTCGGCCTCAGCGGGGACCGCAGCTGCTCACG
CCCCACACACTCACTGGCCAGGAGGCATTCCAGGGTCCGGCCCAAGGTGACCGTCCTGAACTAT
GCCTCTCTGATGACCACGGTTGGCCGGCCACTGAATGAGATGGTCTTGACCCCTCTAACAGAAC
AGGAAGGAGAGGCATACCTGGAGAAGTGTGGCAGCGTCCGGCGGCACACAGTGGCCAATGCCCA
CTCGGACATCCAGCTGCTGGCTATGGCCACCATGATGCACTCAGGGTTGGGGGAGGAGTCTGGA
AGCGAGGACAAACACCTGCTCCTGCCACCCACCTTCCCACCACCACACCGCCAATGCTCCAGTG
AGCCCAGCATCCTTGATAGTCCTGATGAAATGGAACTGGAAGATGTAGCAAGTGGCAGCCAAGA
GGACTCAGAGCTGAATTGTGCTTCCCTCAGCTGAGCCACCACCTCCAGGGACCCATTCCTACTT
TGAGGCTAGGATGAGGACACCCTTCCTCCTCCACGGATCACCCAGGGGCTCTTGCATTGGGCAA
TATTGCCTTACTTCCTTTAGGGCACAAGTCAAGTCTCCACGCCCTTGGGAAACACCTGTTGACC
TCCCAACTCTGGTGTCTGTGACCAGCTCCTCATGCCACCGTTGTTCTGACTTCCAGCCTTGCCT
CATTCACCTGGATCCTCATCCCTGGGCCTTCCGCATCCTATTGGACTGACTGGTACTCCTGGGA
TATAATGCTCTGGCATTATTTTTATAGCAGAAGGTTGGGCTACTACACACGAGCTTCTGAAGTG
TGCCAATCTCTGTAGTTTCTGTTATGATCTTATGAGGCAGAAGCCAACGGGTGGAAAAAACAGT
AAAGATTCTGTGTAGCATGGAAATCAGCTGCAGCCCGTATCGTACATGGTACTGGGAATGTGGC
CTCATCACTTTAATTGCAGAGTTACTGGGAAACCATTTTCCCACTTGTGGGCGAAGATTCATTC
TTAGGAATGTCCAGATATCATGTTCTGTCTACATCATGGACTTTGGCCTAGGAGAACGTATTAG
ACTGGCACGGCCCTGTCTTGCATTAAGCCTCTCAGCCTGTCTGTCTCAGGCTTCCTCTCAGACT
CTGGGAATGAACCTTCTCAGTCACTGGTGCCTTACTCTTTCTCCAGTTTCAGGAACTGACCACT
TTTCTGTTGTGTATACGAGAGGCTGCTGACAGAAGCTGATGTAGACTGTACCTGGATTTCACTT
GAATTTGTAAAATGTGTATTGCTCAAAAAAAATGTTTGCAAATATTTGCACATAGGGTCTTGCA
CTGCTCATTTCCAGTGGAGTGTGTTTGCACACTAAACACAGGTGGACCCCTTCAAAAGGCGGTG
GAATCGCTCAGAACAAAAGGATCAGTAGTAGGTAGGACTCTCATACCTCAGAGCTCTAGAGGAG
CCAGAACTGTGTCTGGAATGGCCTGTGTTGTGAGTGTCTTGGCTTCTAGGGAAGGCTGTGCTGG
GGTCAGGAAACTGCCTCTTCAGCAGGGGAGTGTCGTGGCTGGACTGTATTTGCTTTACATCAGA
CAGGGAGAGATAGGGACGTGGACACGTTTTACTTGCTCCCTGAGATAACAGAAGTACCCAGAAG
TCTCTGGAATCCCTGTCACATCTGCTTCGTGTTGCTATTTGAGGCAGCAGACTTTATTTCTATG
CTAGGTCCTCACTACTGCTCCCTTCAGGCTGGGGAAAGGGAACATTTTGTCTCCATTGAGACAT
GCTCAGATAATTATCTGTTGATCTTGCTAATAGAAACTCAGAAAAATATAGACATTTTCTCCTG
ACCCTGTTTGTGGTATGTGCTGGCACTTTAAGCTCTTCTAAGCTTCAATGGTGTCTCCCTTCTG
GGCAAAGATCTGAAATATGACTATAGCCGGGCTATTAATGGATTCTGCTTTAGAAGTTGCATTT
TAAAAAGTGTTTTAATTTTGTCCTTCCAAGAGATAATGACGAAAGAGAAATGTCTTCATGTGTG
CACACACCCTGGTCCTGCACTTGCATATACACACTTATACCCATACATGTGCACACACACACAC
TCCACATATGCAGAAAGAAATGTTCAGATTCCTTTGAGAGCTTCAATCAAGTAATCTCTCTGTA
TGTGCTGTCTGAAGTCTACAGATTGGAGCTGGAGAAGTGGCTTGGTGCTCAAGATCACTTGCTG
CTCTTGCAGGAGGCCCAAGATGTGATTTAGTTCCTACAACATCAGGCGGCTCACAACCACATGC
CTATAACTCTAGTCCTAGAGGTTCTGATGCTCTCTTCTGTCGTCCTAGGGCGTCTGAGTGTACA
CGCACACATGCACATGCGCGCGCGCGCACACACACACACACACACACACACATACACACACACA
CACACACACACACCACAAGCTGTTAACATATGTTAGTAGGCAGAACATTGCAGTTTGTTTAACC
GATGGCTAGGTTCTTGTTACTACGCCAATCACACACTTGAGATTATTTATTGATCAAGGCAAAG
CAATTAGTCATGTTTGGGTTTGCTTTTTTTGTTGATAAGATTGACAACGCATGCTTTTTAAATG
CCTTTTCCCCTTATTTTCGATGTCTCTGTCGGGACGGAAGTTGTCAGCTAAAGACATGAGCTGT
TGTATTGAAAGTGTACAGGCTGTAGACCTTCATTGCTGCTGACTTCACACAGTTTACAGGATTC
TCGTGGACACACCAGGTATTATTACAGAAATATCCCAGATCATGCACATAAACATTTTATGGGT
GCAAGAGTGTCACCTGTAGGAGTTTTAACCAAACTCCACTCCCCTGGTACCATGGAGACTCATC
TTACTATTTAGTTTAGTGACAGGAAATAATCCCAGCTCTGGGCTCTGCTGGAACTCACAAATTC
TTTCTGGTTGTCTGTTTTCAAAATAGATAGAATAAACATTGTTATGCCGTGGA

hide sequence

RefSeq Acc Id:

XM_039105436 ⟹ XP_038961364

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	108,458,107 - 108,541,213 (-)	NCBI
mRatBN7.2	3	88,001,951 - 88,083,688 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001073619	(Get FASTA)	NCBI Sequence Viewer
	XP_006234709	(Get FASTA)	NCBI Sequence Viewer
	XP_017447389	(Get FASTA)	NCBI Sequence Viewer
	XP_038961364	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	A1L1K1	(Get FASTA)	NCBI Sequence Viewer
	AAI29105	(Get FASTA)	NCBI Sequence Viewer
	EDL79626	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000006291
	ENSRNOP00000006291.7
	ENSRNOP00000078961.1

RefSeq Acc Id:

NP_001073619 ⟸ NM_001080150

- UniProtKB:

A1L1K1 (UniProtKB/Swiss-Prot), A0A8I5ZMF5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MTRGLAPLLPIEFHKMGSFRRPRPRFMSSPLLSELPRFQAARQALQLSSNSAWNSVQTAVINVF
KGGGLQSNELYALNESIRRLLKSELGSFITDYFQNQLLAKGLSFVEEKIKQCEGDNRIEVLAEV
WDHFFTETLPTLQAIFYPVQGQELTIRQISLLGFRDLVLLKVKLGDLLLLSQSKLPSSVIQMLL
ILQSVHEPTGPSEGYLQLEELVKQVVSPFLGLSGDRSCSRPTHSLARRHSRVRPKVTVLNYASL
MTTVGRPLNEMVLTPLTEQEGEAYLEKCGSVRRHTVANAHSDIQLLAMATMMHSGLGEESGSED
KHLLLPPTFPPPHRQCSSEPSILDSPDEMELEDVASGSQEDSELNCASLS

hide sequence

RefSeq Acc Id:	XP_006234709 ⟸ XM_006234647
- Peptide Label:	isoform X1
- UniProtKB:	F1LQP5 (UniProtKB/TrEMBL), A0A8I5ZMF5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTRGLAPLLPIEFHKMGSFRRPRPRFMSSPVLSELPRFQAARQALQLSSNSAWNSVQTAVINVF KGGGLQSNELYALNESIRRLLKSELGSFITDYFQNQLLAKGLSFVEEKIKQCEGDNRIEVLAEV WDHFFTETLPTLQAIFYPVQGQELTIRQISLLGFRDLVLLKVKLGDLLLLSQSKLPSSVIQMLL ILQSVHEPTGPSEGYLQLEELVKQVVSPFLGLSGDRSCSRPTHSLARRHSRVRPKVTVLNYASL MTTVGRPLNEMVLTPLTEQEGEAYLEKCGSVRRHTVANAHSDIQLLAMATMMHSGLGEESGSED KHLLLPPTFPPPHRQCSSEPSILDSPDEMELEDVASGSQEDSELNCASLS hide sequence

RefSeq Acc Id:	XP_017447389 ⟸ XM_017591900
- Peptide Label:	isoform X1
- UniProtKB:	F1LQP5 (UniProtKB/TrEMBL), A0A8I5ZMF5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTRGLAPLLPIEFHKMGSFRRPRPRFMSSPVLSELPRFQAARQALQLSSNSAWNSVQTAVINVF KGGGLQSNELYALNESIRRLLKSELGSFITDYFQNQLLAKGLSFVEEKIKQCEGDNRIEVLAEV WDHFFTETLPTLQAIFYPVQGQELTIRQISLLGFRDLVLLKVKLGDLLLLSQSKLPSSVIQMLL ILQSVHEPTGPSEGYLQLEELVKQVVSPFLGLSGDRSCSRPTHSLARRHSRVRPKVTVLNYASL MTTVGRPLNEMVLTPLTEQEGEAYLEKCGSVRRHTVANAHSDIQLLAMATMMHSGLGEESGSED KHLLLPPTFPPPHRQCSSEPSILDSPDEMELEDVASGSQEDSELNCASLS hide sequence

Ensembl Acc Id:

ENSRNOP00000006291 ⟸ ENSRNOT00000006291

RefSeq Acc Id:	XP_038961364 ⟸ XM_039105436
- Peptide Label:	isoform X1
- UniProtKB:	F1LQP5 (UniProtKB/TrEMBL), A0A8I5ZMF5 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000078961 ⟸ ENSRNOT00000114001

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A1L1K1-F1-model_v2	AlphaFold	A1L1K1	1-370	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692244

Promoter ID:

EPDNEW_R2768

Type:

single initiation site

Name:

Prr5l_1

Description:

proline rich 5 like

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	91,370,173 - 91,370,233	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309969	AgrOrtholog
BioCyc Gene	G2FUF-48609	BioCyc
Ensembl Genes	ENSRNOG00000004666	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000006291	ENTREZGENE
	ENSRNOT00000006291.8	UniProtKB/TrEMBL
	ENSRNOT00000114001.1	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7100178	IMAGE-MGC_LOAD
InterPro	Bit61/PRR5	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:362171	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:156710	IMAGE-MGC_LOAD
NCBI Gene	362171	ENTREZGENE
PANTHER	PROLINE-RICH PROTEIN 5-LIKE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR32428	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	HbrB	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Prr5l	PhenoGen
RatGTEx	ENSRNOG00000004666	RatGTEx
UniProt	A0A8I5ZMF5	ENTREZGENE, UniProtKB/TrEMBL
	A1L1K1	ENTREZGENE
	F1LQP5	ENTREZGENE, UniProtKB/TrEMBL
	PRR5L_RAT	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-12-06	RGD1309969	similar to RIKEN cDNA 2600010E01	RGD1309969_predicted	similar to RIKEN cDNA 2600010E01 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1309969_predicted	similar to RIKEN cDNA 2600010E01 (predicted)	LOC362171_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC362171_predicted	similar to RIKEN cDNA 2600010E01 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

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