Prr5l (proline rich 5 like) - Rat Genome Database

Name: Prr5l
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Prr5l (proline rich 5 like) Rattus norvegicus

Analyze

Symbol:

Prr5l

Name:

proline rich 5 like

RGD ID:

1309969

Description:

Predicted to have ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including TORC2 signaling; positive regulation of phosphatidylinositol 3-kinase signaling; and regulation of protein phosphorylation. Predicted to localize to TORC2 complex. Orthologous to human PRR5L (proline rich 5 like); PARTICIPATES IN mTOR signaling pathway; INTERACTS WITH 6-propyl-2-thiouracil; bis(2-chloroethyl) sulfide; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

LOC362171; proline-rich protein 5-like; protein observed with Rictor-2; Protor-2; Protor2; RGD1309969; similar to RIKEN cDNA 2600010E01

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PRR5L (proline rich 5 like)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Prr5l (proline rich 5 like)	HGNC	Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Prr5l (proline rich 5 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PRR5L (proline rich 5 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PRR5L (proline rich 5 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Prr5l (proline rich 5 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PRR5L (proline rich 5 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	PRR5L (proline rich 5 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Prr5l (proline rich 5 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	PRR5 (proline rich 5)	HGNC	OrthoDB
Alliance orthologs ³
Mus musculus (house mouse):	Prr5l (proline rich 5 like)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Homo sapiens (human):	PRR5L (proline rich 5 like)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Danio rerio (zebrafish):	si:ch211-147k10.5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|TreeFam)

Allele / Splice:

Prr5l^{Tn(sb-T2/Bart3)2.228Mcwi}

Genetic Models:

F344-Prr5l^{Tn(sb-T2/Bart3)2.228Mcwi}

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	88,001,951 - 88,173,532 (-)	NCBI
Rnor_6.0 Ensembl	3	91,291,875 - 91,370,167 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	3	91,290,207 - 91,461,208 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	3	97,950,297 - 98,119,477 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	86,868,129 - 86,948,468 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	3	86,764,033 - 86,844,895 (-)	NCBI
Celera	3	87,111,242 - 87,189,435 (-)	NCBI		Celera
Cytogenetic Map	3	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1-dichloroethene (ISO)

1,2-dichloroethane (ISO)

17beta-estradiol (ISO)

3,4-methylenedioxymethamphetamine (ISO)

4-hydroxyphenyl retinamide (ISO)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

acrolein (ISO)

aflatoxin B1 (ISO)

alpha-pinene (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bis(2-chloroethyl) sulfide (EXP)

bisphenol A (EXP)

butan-1-ol (ISO)

butanal (ISO)

calcitriol (ISO)

carbon nanotube (ISO)

chloroprene (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

clothianidin (ISO)

deoxynivalenol (ISO)

diethylstilbestrol (ISO)

dioxygen (ISO)

diuron (EXP)

dorsomorphin (ISO)

endosulfan (EXP)

folic acid (ISO)

genistein (ISO)

methamphetamine (EXP)

methapyrilene (ISO)

methotrexate (ISO)

N-Nitrosopyrrolidine (ISO)

nickel atom (ISO)

O-methyleugenol (ISO)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sulforaphane (ISO)

tetraphene (ISO)

thimerosal (ISO)

titanium dioxide (ISO)

topotecan (EXP)

trichostatin A (ISO)

valproic acid (ISO)

vorinostat (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

cellular response to oxidative stress (IEA,ISO,ISS)

negative regulation of protein phosphorylation (IEA,ISO,ISS)

negative regulation of signal transduction (IEA)

positive regulation of intracellular protein transport (IEA,ISO,ISS)

positive regulation of mRNA catabolic process (IEA,ISO,ISS)

positive regulation of phosphatidylinositol 3-kinase signaling (IEA,ISO)

positive regulation of protein phosphorylation (IEA,ISO)

regulation of fibroblast migration (IEA,ISO,ISS)

TORC2 signaling (IBA,IEA,ISO,ISS)

Cellular Component

cellular_component (ND)

TORC2 complex (IBA,IEA,ISO,ISS)

Molecular Function

molecular_function (ND)

protein binding (ISO)

ubiquitin protein ligase binding (IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

mTOR signaling pathway (ISO)

References

References - curated


1.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Laplante M and Sabatini DM, Cell. 2012 Apr 13;149(2):274-93. doi: 10.1016/j.cell.2012.03.017.
3.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	RGD automated import pipeline for gene-chemical interactions
5.	RGD comprehensive gene curation

Additional References at PubMed

PMID:12477932	PMID:15489334	PMID:18614015	PMID:21413931	PMID:21964062	PMID:22609986

Genomics

Comparative Map Data

Prr5l
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	88,001,951 - 88,173,532 (-)	NCBI
Rnor_6.0 Ensembl	3	91,291,875 - 91,370,167 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	3	91,290,207 - 91,461,208 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	3	97,950,297 - 98,119,477 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	86,868,129 - 86,948,468 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	3	86,764,033 - 86,844,895 (-)	NCBI
Celera	3	87,111,242 - 87,189,435 (-)	NCBI		Celera
Cytogenetic Map	3	q31	NCBI

PRR5L
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	11	36,296,288 - 36,465,204 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	11	36,296,288 - 36,465,204 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	11	36,317,725 - 36,486,754 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
GRCh37	11	36,317,838 - 36,486,754 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	36,354,131 - 36,443,330 (+)	NCBI	NCBI36		hg18	NCBI36
Celera	11	36,466,181 - 36,637,921 (+)	NCBI
Cytogenetic Map	11	p13-p12	NCBI
HuRef	11	36,017,351 - 36,188,822 (+)	NCBI		HuRef
CHM1_1	11	36,315,873 - 36,485,532 (+)	NCBI		CHM1_1

Prr5l
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	101,543,455 - 101,713,428 (-)	NCBI	GRCm39		mm39
GRCm38	2	101,713,110 - 101,883,052 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	101,714,285 - 101,883,027 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	101,554,442 - 101,679,137 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	2	101,517,087 - 101,598,456 (-)	NCBI			mm8
MGSCv36	2	102,525,319 - 102,608,002 (-)	NCBI			mm8
Celera	2	102,939,329 - 103,063,664 (-)	NCBI		Celera
Cytogenetic Map	2	E2	NCBI

Prr5l
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	9,972,588 - 10,048,669 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955422	9,972,588 - 10,069,411 (-)	NCBI	ChiLan1.0	ChiLan1.0

PRR5L
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	11	36,143,905 - 36,311,659 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	36,223,385 - 36,311,659 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	11	36,269,291 - 36,438,954 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

PRR5L
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	18	31,706,546 - 31,849,491 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	18	31,708,888 - 31,849,365 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Prr5l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936533	1,895,594 - 1,975,442 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PRR5L
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	24,646,867 - 24,812,610 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	24,646,865 - 24,812,642 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	26,811,301 - 26,949,585 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PRR5L
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	28,771,858 - 28,951,201 (-)	NCBI
ChlSab1.1 Ensembl	1	28,771,793 - 28,841,572 (-)	Ensembl

Prr5l
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624767	10,781,954 - 10,950,142 (-)	NCBI

Position Markers

D3Rat76

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	3	91,344,449 - 91,344,651	NCBI	Rnor6.0
Rnor_5.0	3	98,003,200 - 98,003,402	UniSTS	Rnor5.0
RGSC_v3.4	3	86,920,827 - 86,921,029	UniSTS	RGSC3.4
RGSC_v3.4	3	86,920,826 - 86,921,029	RGD	RGSC3.4
RGSC_v3.1	3	86,817,255 - 86,817,457	RGD
Celera	3	87,163,691 - 87,163,893	UniSTS
RH 3.4 Map	3	671.1	RGD
RH 3.4 Map	3	671.1	UniSTS
RH 2.0 Map	3	451.7	RGD
SHRSP x BN Map	3	46.7498	RGD
Cytogenetic Map	3	q31	UniSTS

D3Rat265

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	3	91,325,598 - 91,325,787	NCBI	Rnor6.0
Rnor_5.0	3	97,984,349 - 97,984,538	UniSTS	Rnor5.0
RGSC_v3.4	3	86,900,973 - 86,901,162	UniSTS	RGSC3.4
RGSC_v3.4	3	86,900,972 - 86,901,162	RGD	RGSC3.4
RGSC_v3.1	3	86,797,401 - 86,797,590	RGD
Celera	3	87,143,814 - 87,144,003	UniSTS
RH 3.4 Map	3	676.0	RGD
RH 3.4 Map	3	676.0	UniSTS
RH 2.0 Map	3	455.2	RGD
SHRSP x BN Map	3	46.1498	RGD
Cytogenetic Map	3	q31	UniSTS

D3Got38

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	3	91,333,504 - 91,333,763	NCBI	Rnor6.0
Rnor_6.0	3	91,145,834 - 91,146,093	NCBI	Rnor6.0
Rnor_5.0	3	97,805,848 - 97,806,107	UniSTS	Rnor5.0
Rnor_5.0	3	97,992,255 - 97,992,514	UniSTS	Rnor5.0
RGSC_v3.4	3	86,908,881 - 86,909,141	RGD	RGSC3.4
RGSC_v3.4	3	86,908,882 - 86,909,141	UniSTS	RGSC3.4
RGSC_v3.1	3	86,805,310 - 86,805,569	RGD
Celera	3	87,151,720 - 87,151,979	UniSTS
RH 3.4 Map	3	669.9	UniSTS
RH 3.4 Map	3	669.9	RGD
RH 2.0 Map	3	459.3	RGD
Cytogenetic Map	3	q31	UniSTS

BE110692

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	3	91,345,841 - 91,345,995	NCBI	Rnor6.0
Rnor_5.0	3	98,004,592 - 98,004,746	UniSTS	Rnor5.0
RGSC_v3.4	3	86,922,219 - 86,922,373	UniSTS	RGSC3.4
Celera	3	87,165,083 - 87,165,237	UniSTS
RH 3.4 Map	3	678.0	UniSTS
Cytogenetic Map	3	q31	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2290452	Scl56	Serum cholesterol level QTL 56	2.26		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	3	1	95176874	Rat
1358905	Hrtrt17	Heart rate QTL 17	5.9	0.000014	heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	10094081	93415837	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	10639528	127023997	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	10639528	127023997	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	30114912	123700444	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	30846101	172879276	Rat
1354604	Bw36	Body weight QTL 36	2.9		body mass (VT:0001259)	body weight (CMO:0000012)	3	33477354	108914061	Rat
61419	Cia11	Collagen induced arthritis QTL 11	5.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	3	34394121	103141944	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	39248391	140271184	Rat
1331777	Bw24	Body weight QTL 24	3.503		body mass (VT:0001259)	body weight (CMO:0000012)	3	40523593	92654473	Rat
1331795	Rf30	Renal function QTL 30	3.708		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	3	40523593	92654473	Rat
1354597	Kidm13	Kidney mass QTL 13	2.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	3	43295930	108914061	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	43295930	163640485	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	43295930	163640485	Rat
1300178	Hrtrt4	Heart rate QTL 4	3.74		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	45406058	94467785	Rat
1581503	Cm58	Cardiac mass QTL 58	2.7	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	45406058	127023997	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	45406058	177699992	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	48561928	155263151	Rat
1358186	Ept2	Estrogen-induced pituitary tumorigenesis QTL 2	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	48562146	115249962	Rat
2292613	Ept16	Estrogen-induced pituitary tumorigenesis QTL 16	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	48562146	115249962	Rat
631665	Bw8	Body weight QTL 8	5.5		body mass (VT:0001259)	body weight (CMO:0000012)	3	51821836	124513579	Rat
724523	Tsu1	Thymus enlargement suppressive QTL 1	3.84		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	3	51822008	120917851	Rat
1582218	Bw74	Body weight QTL 74	3.9	0.0021	body mass (VT:0001259)	body weight (CMO:0000012)	3	54630948	119830094	Rat
1582238	Bw68	Body weight QTL 68	3.2	0.0064	body mass (VT:0001259)	body weight (CMO:0000012)	3	54630948	119830094	Rat
1582239	Epfw1	Epididymal fat weight QTL 1	4.5	0.0006	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	3	54630948	119830094	Rat
61377	Edpm3	Estrogen-dependent pituitary mass QTL 3	7.05	0.038	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	54631046	93415673	Rat
731180	Bp152	Blood pressure QTL 152		0.03	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	55245276	95176874	Rat
731180	Bp152	Blood pressure QTL 152		0.03	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	3	55245276	95176874	Rat
731180	Bp152	Blood pressure QTL 152		0.03	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	55245276	95176874	Rat
1358293	Bw38	Body weight QTL 38	6	0.0000031	body mass (VT:0001259)	body weight (CMO:0000012)	3	56735995	101735995	Rat
1581568	Rf53	Renal function QTL 53			total urine protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	3	58204463	170534769	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	61241033	165369047	Rat
1300111	Rf12	Renal function QTL 12	3.78		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	62922868	127023997	Rat
631200	Cm25	Cardiac mass QTL 25	4.8	0.0001	heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	3	63049050	92654302	Rat
1582221	Kidm30	Kidney mass QTL 30	3.5	0.0008	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	3	66711607	119830094	Rat
1582210	Bw71	Body weight QTL 71	3.3	0.0012	body mass (VT:0001259)	body weight (CMO:0000012)	3	66711607	119830094	Rat
12879848	Bw181	Body weght QTL 181		0.015	body mass (VT:0001259)	body weight (CMO:0000012)	3	72672290	127023997	Rat
2301414	Kidm37	Kidney mass QTL 37		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	72973445	127023997	Rat
1600376	Arunc5	Aerobic running capacity QTL 5		0.21	exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	3	78700444	123700444	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	total urine protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	81136227	154416635	Rat
2302273	Gluco35	Glucose level QTL 35	5.3	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	83817637	119509260	Rat
7387306	Bw124	Body weight QTL 124	3.2	0.0003	body mass (VT:0001259)	body weight (CMO:0000012)	3	88910015	133910015	Rat

Genetic Models

This gene Prr5l is modified in the following models/strains

F344-Prr5l^{Tn(sb-T2/Bart3)2.228Mcwi}

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	540
Count of miRNA genes:	240
Interacting mature miRNAs:	285
Transcripts:	ENSRNOT00000006291
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	1				2				6	16	17	11
Low	2	43	49	33	17	33	5	6	68	19	24		5
Below cutoff			8	8		8	3	5					3

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001080150	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006234647	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017591900	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105436	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AY724495	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC129104	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000118	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000006291 ⟹ ENSRNOP00000006291

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	3	91,291,875 - 91,370,167 (-)	Ensembl

RefSeq Acc Id:

NM_001080150 ⟹ NP_001073619

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	88,003,614 - 88,082,763 (-)	NCBI
Rnor_6.0	3	91,291,870 - 91,370,167 (-)	NCBI
Rnor_5.0	3	97,950,297 - 98,119,477 (-)	NCBI
RGSC_v3.4	3	86,868,129 - 86,948,468 (-)	RGD
Celera	3	87,111,242 - 87,189,435 (-)	RGD

Sequence:

show sequence

CGCTGAAGAGAAACCTGAGCAGGACACGACCCAGCGGAGGGCAGAGGTGGGAGAGGACCTCGGG
AGGGCGAGCGAGGCAAGAACAATCCAAAATCGCTGGTTTCTCTCCAGCGAGAAAACTTTCCTTG
GGACGACGGAAACTTTTTTCCTGCGCGCGCAGAGTCTGGGACAGAGGCGAGCGGCGGGTGTACG
CGGCTCCGCTCCTGTGACTCACGCCCGGGACCCCAAGGGGGTGCTGGCTGACAGTAGGGTTTTA
AGACACCCCAGAAGCAGCGTTGAGGGAAGCCTTTCTTTCCTGTGGGTGGCCAGAAGCTTCTGGT
CCTCAAGACACAGCTCAATCCTCACCTGGACTTATGACCCGCGGCCTTGCTCCCCTCCTGCCCA
TTGAGTTCCACAAGATGGGCTCCTTCCGCCGGCCTAGACCACGATTTATGAGCTCCCCTCTGCT
CAGCGAGCTGCCCCGCTTTCAGGCTGCCCGGCAGGCTCTGCAACTAAGTTCCAACTCAGCCTGG
AACAGTGTGCAGACGGCTGTGATCAACGTTTTCAAAGGGGGCGGCTTGCAGAGCAATGAGCTGT
ATGCACTGAACGAAAGCATCAGGCGGCTGCTGAAGAGTGAACTTGGATCGTTCATTACTGACTA
CTTCCAGAACCAGCTTCTTGCAAAAGGACTGTCCTTTGTGGAGGAGAAGATCAAGCAGTGTGAA
GGTGACAATCGCATTGAGGTTCTGGCTGAAGTCTGGGACCACTTCTTCACCGAGACACTCCCTA
CCCTGCAGGCAATATTTTATCCGGTTCAGGGACAGGAGCTGACCATCCGCCAGATCTCCCTGCT
GGGCTTCCGGGACCTGGTCTTGCTGAAGGTGAAGCTGGGTGACTTGCTGCTGTTGTCACAGTCC
AAGTTGCCTTCTTCTGTTATACAGATGCTTCTCATTCTGCAGAGTGTTCACGAGCCCACAGGCC
CAAGTGAGGGCTATTTGCAGCTGGAGGAGCTGGTGAAGCAAGTGGTGTCTCCCTTCCTCGGCCT
CAGCGGGGACCGCAGCTGCTCACGCCCCACACACTCACTGGCCAGGAGGCATTCCAGGGTCCGG
CCCAAGGTGACCGTCCTGAACTATGCCTCTCTGATGACCACGGTTGGCCGGCCACTGAATGAGA
TGGTCTTGACCCCTCTAACAGAACAGGAAGGAGAGGCATACCTGGAGAAGTGTGGCAGCGTCCG
GCGGCACACAGTGGCCAATGCCCACTCGGACATCCAGCTGCTGGCTATGGCCACCATGATGCAC
TCAGGGTTGGGGGAGGAGTCTGGAAGCGAGGACAAACACCTGCTCCTGCCACCCACCTTCCCAC
CACCACACCGCCAATGCTCCAGTGAGCCCAGCATCCTTGATAGTCCTGATGAAATGGAACTGGA
AGATGTAGCAAGTGGCAGCCAAGAGGACTCAGAGCTGAATTGTGCTTCCCTCAGCTGAGCCACC
ACCTCCAGGGACCCATTCCTACTTTGAGGCTAGGATGAGGACACCCTTCCTCCTCCACGGATCA
CCCAGGGGCTCTTGCATTGGGCAATATTGCCTTACTTCCTTTAGGGCACAAGTCAAGTCTCCAC
GCCCTTGGGAAACACCTGTTGACCTCCCAACTCTGGTGTCTGTGACCAGCTCCTCATGCCACCG
TTGTTCTGACTTCCAGCCTTGCCTCATTCACCTGGATCCTCATCCCTGGGCCTTCCGCATCCTA
TTGGACTGACTGGTACTCCTGGGATATAATGCTCTGGCATTATTTTTATAGCAGAAGGTTGGGC
TACTACACACGAGCTTCTGAAGTGTGCCAATCTCTGTAGTTTCTGTTATGATCTTATGAGGCAG
AAGCCAACGGGTGGAAAAAACAGTAAAGATTCTGTGTAGCATGGAAATCAGCTGCAGCCCGTAT
CGTACATGGTACTGGGAATGTGGCCTCATCACTTTAATTGCAGAGTTACTGGGAAACCATTTTC
CCACTTGTGGGCGAAGATTCATTCTTAGGAATGTCCAGATATCATGTTCTGTCTACATCATGGA
CTTTGGCCTAGGAGAACGTATTAGACTGGCACGGCCCTGTCTTGCATTAAGCCTCTCAGCCTGT
CTGTCTCAGGCTTCCTCTCAGACTCTGGGAATGAACCTTCTCAGTCACTGGTGCCTTACTCTTT
CTCCAGTTTCAGGAACTGACCACTTTTCTGTTGTGTATACGAGAGGCTGCTGACAGAAGCTGAT
GTAGACTGTACCTGGATTTCACTTGAATTTGTAAAATGTGTATTGCTCAAAAAAAATGTTTGCA
AATATTTGCACATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006234647 ⟹ XP_006234709

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	88,001,951 - 88,083,012 (-)	NCBI
Rnor_6.0	3	91,290,207 - 91,370,435 (-)	NCBI
Rnor_5.0	3	97,950,297 - 98,119,477 (-)	NCBI

Sequence:

show sequence

ACTTCCCTTGATTTGCAGCATCCTCCCCTGCTTTTTAGGACCACGAGCTTGGATTTCCTGAAAT
TGTTGAAGTGGATTTAAGCGCAGGTCTTCCGTCTCCTCTTGTTGTTGGAGAGGAGGCGTAGGAT
GGGGTGAAGCGAAGCGGGGGCGTTGGAGAGAAACCACAGCGATGTGCACCGGACAGGAAAAGTG
GGAGGAGGAGGGGGAGGAGGAGAGGAGGCGGCCGTAAGTTGAGAGAGGAGGGAAACAGTCACCA
GCCTGAGAGCTACGCTGAAGAGAAACCTGAGCAGGACACGACCCAGCGGAGGGCAGAGGTGGGA
GAGGACCTCGGGAGGGCGAGCGAGGCAAGAACAATCCAAAATCGCTGGTTTCTCTCCAGCGAGA
AAACTTTCCTTGGGACGACGGAAACTTTTTTCCTGCGCGCGCAGAGTCTGGGACAGAGGCGAGC
GGCGGGTGTACGCGGCTCCGCTCCTGTGACTCACGCCCGGGACCCCAAGGGGGTGAGTGGGGAA
GTCCCTGGAGGGCCTGGAGTCATCCTTCTGCAACTCCTCAGACTCGGAAAATAACTCTCCTGGC
GTGATCTGGGGGTGGGAGTGGGAGCACCGGAGACAGCGAGACTGAGGGGAGACTCCGCGTGGTT
AAGGAACCTCCGCATCGGATGCTGTAGGCGGGGAGGTAGACTACCAAGAGGTGCTGGCTGACAG
TAGGGTTTTAAGACACCCCAGAAGCAGCGTTGAGGGAAGCCTTTCTTTCCTGTGGGTGGCCAGA
AGCTTCTGGTCCTCAAGACACAGCTCAATCCTCACCTGGACTTATGACCCGCGGCCTTGCTCCC
CTCCTGCCCATTGAGTTCCACAAGATGGGCTCCTTCCGCCGGCCTAGACCACGATTTATGAGCT
CCCCTGTGCTCAGCGAGCTGCCCCGCTTTCAGGCTGCCCGGCAGGCTCTGCAACTAAGTTCCAA
CTCAGCCTGGAACAGTGTGCAGACGGCTGTGATCAACGTTTTCAAAGGGGGCGGCTTGCAGAGC
AATGAGCTGTATGCACTGAACGAAAGCATCAGGCGGCTGCTGAAGAGTGAACTTGGATCGTTCA
TTACTGACTACTTCCAGAACCAGCTTCTTGCAAAAGGACTGTCCTTTGTGGAGGAGAAGATCAA
GCAGTGTGAAGGTGACAATCGCATTGAGGTTCTGGCTGAAGTCTGGGACCACTTCTTCACCGAG
ACACTCCCTACCCTGCAGGCAATATTTTATCCGGTTCAGGGACAGGAGCTGACCATCCGCCAGA
TCTCCCTGCTGGGCTTCCGGGACCTGGTCTTGCTGAAGGTGAAGCTGGGTGACTTGCTGCTGTT
GTCACAGTCCAAGTTGCCTTCTTCTGTTATACAGATGCTTCTCATTCTGCAGAGTGTTCACGAG
CCCACAGGCCCAAGTGAGGGCTATTTGCAGCTGGAGGAGCTGGTGAAGCAAGTGGTGTCTCCCT
TCCTCGGCCTCAGCGGGGACCGCAGCTGCTCACGCCCCACACACTCACTGGCCAGGAGGCATTC
CAGGGTCCGGCCCAAGGTGACCGTCCTGAACTATGCCTCTCTGATGACCACGGTTGGCCGGCCA
CTGAATGAGATGGTCTTGACCCCTCTAACAGAACAGGAAGGAGAGGCATACCTGGAGAAGTGTG
GCAGCGTCCGGCGGCACACAGTGGCCAATGCCCACTCGGACATCCAGCTGCTGGCTATGGCCAC
CATGATGCACTCAGGGTTGGGGGAGGAGTCTGGAAGCGAGGACAAACACCTGCTCCTGCCACCC
ACCTTCCCACCACCACACCGCCAATGCTCCAGTGAGCCCAGCATCCTTGATAGTCCTGATGAAA
TGGAACTGGAAGATGTAGCAAGTGGCAGCCAAGAGGACTCAGAGCTGAATTGTGCTTCCCTCAG
CTGAGCCACCACCTCCAGGGACCCATTCCTACTTTGAGGCTAGGATGAGGACACCCTTCCTCCT
CCACGGATCACCCAGGGGCTCTTGCATTGGGCAATATTGCCTTACTTCCTTTAGGGCACAAGTC
AAGTCTCCACGCCCTTGGGAAACACCTGTTGACCTCCCAACTCTGGTGTCTGTGACCAGCTCCT
CATGCCACCGTTGTTCTGACTTCCAGCCTTGCCTCATTCACCTGGATCCTCATCCCTGGGCCTT
CCGCATCCTATTGGACTGACTGGTACTCCTGGGATATAATGCTCTGGCATTATTTTTATAGCAG
AAGGTTGGGCTACTACACACGAGCTTCTGAAGTGTGCCAATCTCTGTAGTTTCTGTTATGATCT
TATGAGGCAGAAGCCAACGGGTGGAAAAAACAGTAAAGATTCTGTGTAGCATGGAAATCAGCTG
CAGCCCGTATCGTACATGGTACTGGGAATGTGGCCTCATCACTTTAATTGCAGAGTTACTGGGA
AACCATTTTCCCACTTGTGGGCGAAGATTCATTCTTAGGAATGTCCAGATATCATGTTCTGTCT
ACATCATGGACTTTGGCCTAGGAGAACGTATTAGACTGGCACGGCCCTGTCTTGCATTAAGCCT
CTCAGCCTGTCTGTCTCAGGCTTCCTCTCAGACTCTGGGAATGAACCTTCTCAGTCACTGGTGC
CTTACTCTTTCTCCAGTTTCAGGAACTGACCACTTTTCTGTTGTGTATACGAGAGGCTGCTGAC
AGAAGCTGATGTAGACTGTACCTGGATTTCACTTGAATTTGTAAAATGTGTATTGCTCAAAAAA
AATGTTTGCAAATATTTGCACATAGGGTCTTGCACTGCTCATTTCCAGTGGAGTGTGTTTGCAC
ACTAAACACAGGTGGACCCCTTCAAAAGGCGGTGGAATCGCTCAGAACAAAAGGATCAGTAGTA
GGTAGGACTCTCATACCTCAGAGCTCTAGAGGAGCCAGAACTGTGTCTGGAATGGCCTGTGTTG
TGAGTGTCTTGGCTTCTAGGGAAGGCTGTGCTGGGGTCAGGAAACTGCCTCTTCAGCAGGGGAG
TGTCGTGGCTGGACTGTATTTGCTTTACATCAGACAGGGAGAGATAGGGACGTGGACACGTTTT
ACTTGCTCCCTGAGATAACAGAAGTACCCAGAAGTCTCTGGAATCCCTGTCACATCTGCTTCGT
GTTGCTATTTGAGGCAGCAGACTTTATTTCTATGCTAGGTCCTCACTACTGCTCCCTTCAGGCT
GGGGAAAGGGAACATTTTGTCTCCATTGAGACATGCTCAGATAATTATCTGTTGATCTTGCTAA
TAGAAACTCAGAAAAATATAGACATTTTCTCCTGACCCTGTTTGTGGTATGTGCTGGCACTTTA
AGCTCTTCTAAGCTTCAATGGTGTCTCCCTTCTGGGCAAAGATCTGAAATATGACTATAGCCGG
GCTATTAATGGATTCTGCTTTAGAAGTTGCATTTTAAAAAGTGTTTTAATTTTGTCCTTCCAAG
AGATAATGACGAAAGAGAAATGTCTTCATGTGTGCACACACCCTGGTCCTGCACTTGCATATAC
ACACTTATACCCATACATGTGCACACACACACACTCCACATATGCAGAAAGAAATGTTCAGATT
CCTTTGAGAGCTTCAATCAAGTAATCTCTCTGTATGTGCTGTCTGAAGTCTACAGATTGGAGCT
GGAGAAGTGGCTTGGTGCTCAAGATCACTTGCTGCTCTTGCAGGAGGCCCAAGATGTGATTTAG
TTCCTACAACATCAGGCGGCTCACAACCACATGCCTATAACTCTAGTCCTAGAGGTTCTGATGC
TCTCTTCTGTCGTCCTAGGGCGTCTGAGTGTACACGCACACATGCACATGCGCGCGCGCGCACA
CACACACACACACACACACACATACACACACACACACACACACACACCACAAGCTGTTAACATA
TGTTAGTAGGCAGAACATTGCAGTTTGTTTAACCGATGGCTAGGTTCTTGTTACTACGCCAATC
ACACACTTGAGATTATTTATTGATCAAGGCAAAGCAATTAGTCATGTTTGGGTTTGCTTTTTTT
GTTGATAAGATTGACAACGCATGCTTTTTAAATGCCTTTTCCCCTTATTTTCGATGTCTCTGTC
GGGACGGAAGTTGTCAGCTAAAGACATGAGCTGTTGTATTGAAAGTGTACAGGCTGTAGACCTT
CATTGCTGCTGACTTCACACAGTTTACAGGATTCTCGTGGACACACCAGGTATTATTACAGAAA
TATCCCAGATCATGCACATAAACATTTTATGGGTGCAAGAGTGTCACCTGTAGGAGTTTTAACC
AAACTCCACTCCCCTGGTACCATGGAGACTCATCTTACTATTTAGTTTAGTGACAGGAAATAAT
CCCAGCTCTGGGCTCTGCTGGAACTCACAAATTCTTTCTGGTTGTCTGTTTTCAAAATAGATAG
AATAAACATTGTTATGCCGTGGA

hide sequence

RefSeq Acc Id:

XM_006234648 ⟹ XP_006234710

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	91,290,207 - 91,461,208 (-)	NCBI
Rnor_5.0	3	97,950,297 - 98,119,477 (-)	NCBI

Sequence:

show sequence

TCCTGCTGGTAGAGGCGGCCTTTCAGATTCTGTTTTCGTTCCCATTAGTTTTCAGAGTCAGTGA
GTGGTGAGTGGGGCCTACTGTCAAAGTGTCACCACCTCAGAAGGCTGGAAGGACAGGACACTTC
ACCTCTCCTGGGAAAGTTCTGAAGATATGTTGTGTTCGTGAAAACTTCGCTCGGAAATTGAACC
CCGGATCCTTAAATTCATTTCGCTACGCTAATGAAGACGCAAACAAGTGTGGAATCGGTTTGAG
GACCTATCTTTAAAACGCATTCGCGCGTGCGCGCCCCCAAGCAGCAACAAAAAACTCTCCCAGC
CTCAGAAATGTGCTGCAGAACTCCAGTCCTTTTTTATCTGGTCGCACGTACACCTCTGGACTCC
AGGAGGAGGGTTTAGCGGTGGGAGACCAATCTCCTCTTGGCTTAATGAAAGGTGCTGGCTGACA
GTAGGGTTTTAAGACACCCCAGAAGCAGCGTTGAGGGAAGCCTTTCTTTCCTGTGGGTGGCCAG
AAGCTTCTGGTCCTCAAGACACAGCTCAATCCTCACCTGGACTTATGACCCGCGGCCTTGCTCC
CCTCCTGCCCATTGAGTTCCACAAGATGGGCTCCTTCCGCCGGCCTAGACCACGATTTATGAGC
TCCCCTGTGCTCAGCGAGCTGCCCCGCTTTCAGGCTGCCCGGCAGGCTCTGCAACTAAGTTCCA
ACTCAGCCTGGAACAGTGTGCAGACGGCTGTGATCAACGTTTTCAAAGGGGGCGGCTTGCAGAG
CAATGAGCTGTATGCACTGAACGAAAGCATCAGGCGGCTGCTGAAGAGTGAACTTGGATCGTTC
ATTACTGACTACTTCCAGAACCAGCTTCTTGCAAAAGGACTGTCCTTTGTGGAGGAGAAGATCA
AGCAGTGTGAAGGTGACAATCGCATTGAGGTTCTGGCTGAAGTCTGGGACCACTTCTTCACCGA
GACACTCCCTACCCTGCAGGCAATATTTTATCCGGTTCAGGGACAGGAGCTGACCATCCGCCAG
ATCTCCCTGCTGGGCTTCCGGGACCTGGTCTTGCTGAAGGTGAAGCTGGGTGACTTGCTGCTGT
TGTCACAGTCCAAGTTGCCTTCTTCTGTTATACAGATGCTTCTCATTCTGCAGAGTGTTCACGA
GCCCACAGGCCCAAGTGAGGGCTATTTGCAGCTGGAGGAGCTGGTGAAGCAAGTGGTGTCTCCC
TTCCTCGGCCTCAGCGGGGACCGCAGCTGCTCACGCCCCACACACTCACTGGCCAGGAGGCATT
CCAGGGTCCGGCCCAAGGTGACCGTCCTGAACTATGCCTCTCTGATGACCACGGTTGGCCGGCC
ACTGAATGAGATGGTCTTGACCCCTCTAACAGAACAGGAAGGAGAGGCATACCTGGAGAAGTGT
GGCAGCGTCCGGCGGCACACAGTGGCCAATGCCCACTCGGACATCCAGCTGCTGGCTATGGCCA
CCATGATGCACTCAGGGTTGGGGGAGGAGTCTGGAAGCGAGGACAAACACCTGCTCCTGCCACC
CACCTTCCCACCACCACACCGCCAATGCTCCAGTGAGCCCAGCATCCTTGATAGTCCTGATGAA
ATGGAACTGGAAGATGTAGCAAGTGGCAGCCAAGAGGACTCAGAGCTGAATTGTGCTTCCCTCA
GCTGAGCCACCACCTCCAGGGACCCATTCCTACTTTGAGGCTAGGATGAGGACACCCTTCCTCC
TCCACGGATCACCCAGGGGCTCTTGCATTGGGCAATATTGCCTTACTTCCTTTAGGGCACAAGT
CAAGTCTCCACGCCCTTGGGAAACACCTGTTGACCTCCCAACTCTGGTGTCTGTGACCAGCTCC
TCATGCCACCGTTGTTCTGACTTCCAGCCTTGCCTCATTCACCTGGATCCTCATCCCTGGGCCT
TCCGCATCCTATTGGACTGACTGGTACTCCTGGGATATAATGCTCTGGCATTATTTTTATAGCA
GAAGGTTGGGCTACTACACACGAGCTTCTGAAGTGTGCCAATCTCTGTAGTTTCTGTTATGATC
TTATGAGGCAGAAGCCAACGGGTGGAAAAAACAGTAAAGATTCTGTGTAGCATGGAAATCAGCT
GCAGCCCGTATCGTACATGGTACTGGGAATGTGGCCTCATCACTTTAATTGCAGAGTTACTGGG
AAACCATTTTCCCACTTGTGGGCGAAGATTCATTCTTAGGAATGTCCAGATATCATGTTCTGTC
TACATCATGGACTTTGGCCTAGGAGAACGTATTAGACTGGCACGGCCCTGTCTTGCATTAAGCC
TCTCAGCCTGTCTGTCTCAGGCTTCCTCTCAGACTCTGGGAATGAACCTTCTCAGTCACTGGTG
CCTTACTCTTTCTCCAGTTTCAGGAACTGACCACTTTTCTGTTGTGTATACGAGAGGCTGCTGA
CAGAAGCTGATGTAGACTGTACCTGGATTTCACTTGAATTTGTAAAATGTGTATTGCTCAAAAA
AAATGTTTGCAAATATTTGCACATAGGGTCTTGCACTGCTCATTTCCAGTGGAGTGTGTTTGCA
CACTAAACACAGGTGGACCCCTTCAAAAGGCGGTGGAATCGCTCAGAACAAAAGGATCAGTAGT
AGGTAGGACTCTCATACCTCAGAGCTCTAGAGGAGCCAGAACTGTGTCTGGAATGGCCTGTGTT
GTGAGTGTCTTGGCTTCTAGGGAAGGCTGTGCTGGGGTCAGGAAACTGCCTCTTCAGCAGGGGA
GTGTCGTGGCTGGACTGTATTTGCTTTACATCAGACAGGGAGAGATAGGGACGTGGACACGTTT
TACTTGCTCCCTGAGATAACAGAAGTACCCAGAAGTCTCTGGAATCCCTGTCACATCTGCTTCG
TGTTGCTATTTGAGGCAGCAGACTTTATTTCTATGCTAGGTCCTCACTACTGCTCCCTTCAGGC
TGGGGAAAGGGAACATTTTGTCTCCATTGAGACATGCTCAGATAATTATCTGTTGATCTTGCTA
ATAGAAACTCAGAAAAATATAGACATTTTCTCCTGACCCTGTTTGTGGTATGTGCTGGCACTTT
AAGCTCTTCTAAGCTTCAATGGTGTCTCCCTTCTGGGCAAAGATCTGAAATATGACTATAGCCG
GGCTATTAATGGATTCTGCTTTAGAAGTTGCATTTTAAAAAGTGTTTTAATTTTGTCCTTCCAA
GAGATAATGACGAAAGAGAAATGTCTTCATGTGTGCACACACCCTGGTCCTGCACTTGCATATA
CACACTTATACCCATACATGTGCACACACACACACTCCACATATGCAGAAAGAAATGTTCAGAT
TCCTTTGAGAGCTTCAATCAAGTAATCTCTCTGTATGTGCTGTCTGAAGTCTACAGATTGGAGC
TGGAGAAGTGGCTTGGTGCTCAAGATCACTTGCTGCTCTTGCAGGAGGCCCAAGATGTGATTTA
GTTCCTACAACATCAGGCGGCTCACAACCACATGCCTATAACTCTAGTCCTAGAGGTTCTGATG
CTCTCTTCTGTCGTCCTAGGGCGTCTGAGTGTACACGCACACATGCACATGCGCGCGCGCGCAC
ACACACACACACACACACACACATACACACACACACACACACACACACCACAAGCTGTTAACAT
ATGTTAGTAGGCAGAACATTGCAGTTTGTTTAACCGATGGCTAGGTTCTTGTTACTACGCCAAT
CACACACTTGAGATTATTTATTGATCAAGGCAAAGCAATTAGTCATGTTTGGGTTTGCTTTTTT
TGTTGATAAGATTGACAACGCATGCTTTTTAAATGCCTTTTCCCCTTATTTTCGATGTCTCTGT
CGGGACGGAAGTTGTCAGCTAAAGACATGAGCTGTTGTATTGAAAGTGTACAGGCTGTAGACCT
TCATTGCTGCTGACTTCACACAGTTTACAGGATTCTCGTGGACACACCAGGTATTATTACAGAA
ATATCCCAGATCATGCACATAAACATTTTATGGGTGCAAGAGTGTCACCTGTAGGAGTTTTAAC
CAAACTCCACTCCCCTGGTACCATGGAGACTCATCTTACTATTTAGTTTAGTGACAGGAAATAA
TCCCAGCTCTGGGCTCTGCTGGAACTCACAAATTCTTTCTGGTTGTCTGTTTTCAAAATAGATA
GAATAAACATTGTTATGCCGTGGA

hide sequence

RefSeq Acc Id:

XM_017591900 ⟹ XP_017447389

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	88,001,951 - 88,173,532 (-)	NCBI
Rnor_6.0	3	91,290,207 - 91,461,208 (-)	NCBI

Sequence:

show sequence

TCCTGCTGGTAGAGGCGGCCTTTCAGATTCTGTTTTCGTTCCCATTAGTTTTCAGAGTCAGTGA
GTGGTGAGTGGGGCCTACTGTCAAAGTGTCACCACCTCAGAAGGCTGGAAGGACAGGACACTTC
ACCTCTCCTGGGAAAGGTGCTGGCTGACAGTAGGGTTTTAAGACACCCCAGAAGCAGCGTTGAG
GGAAGCCTTTCTTTCCTGTGGGTGGCCAGAAGCTTCTGGTCCTCAAGACACAGCTCAATCCTCA
CCTGGACTTATGACCCGCGGCCTTGCTCCCCTCCTGCCCATTGAGTTCCACAAGATGGGCTCCT
TCCGCCGGCCTAGACCACGATTTATGAGCTCCCCTGTGCTCAGCGAGCTGCCCCGCTTTCAGGC
TGCCCGGCAGGCTCTGCAACTAAGTTCCAACTCAGCCTGGAACAGTGTGCAGACGGCTGTGATC
AACGTTTTCAAAGGGGGCGGCTTGCAGAGCAATGAGCTGTATGCACTGAACGAAAGCATCAGGC
GGCTGCTGAAGAGTGAACTTGGATCGTTCATTACTGACTACTTCCAGAACCAGCTTCTTGCAAA
AGGACTGTCCTTTGTGGAGGAGAAGATCAAGCAGTGTGAAGGTGACAATCGCATTGAGGTTCTG
GCTGAAGTCTGGGACCACTTCTTCACCGAGACACTCCCTACCCTGCAGGCAATATTTTATCCGG
TTCAGGGACAGGAGCTGACCATCCGCCAGATCTCCCTGCTGGGCTTCCGGGACCTGGTCTTGCT
GAAGGTGAAGCTGGGTGACTTGCTGCTGTTGTCACAGTCCAAGTTGCCTTCTTCTGTTATACAG
ATGCTTCTCATTCTGCAGAGTGTTCACGAGCCCACAGGCCCAAGTGAGGGCTATTTGCAGCTGG
AGGAGCTGGTGAAGCAAGTGGTGTCTCCCTTCCTCGGCCTCAGCGGGGACCGCAGCTGCTCACG
CCCCACACACTCACTGGCCAGGAGGCATTCCAGGGTCCGGCCCAAGGTGACCGTCCTGAACTAT
GCCTCTCTGATGACCACGGTTGGCCGGCCACTGAATGAGATGGTCTTGACCCCTCTAACAGAAC
AGGAAGGAGAGGCATACCTGGAGAAGTGTGGCAGCGTCCGGCGGCACACAGTGGCCAATGCCCA
CTCGGACATCCAGCTGCTGGCTATGGCCACCATGATGCACTCAGGGTTGGGGGAGGAGTCTGGA
AGCGAGGACAAACACCTGCTCCTGCCACCCACCTTCCCACCACCACACCGCCAATGCTCCAGTG
AGCCCAGCATCCTTGATAGTCCTGATGAAATGGAACTGGAAGATGTAGCAAGTGGCAGCCAAGA
GGACTCAGAGCTGAATTGTGCTTCCCTCAGCTGAGCCACCACCTCCAGGGACCCATTCCTACTT
TGAGGCTAGGATGAGGACACCCTTCCTCCTCCACGGATCACCCAGGGGCTCTTGCATTGGGCAA
TATTGCCTTACTTCCTTTAGGGCACAAGTCAAGTCTCCACGCCCTTGGGAAACACCTGTTGACC
TCCCAACTCTGGTGTCTGTGACCAGCTCCTCATGCCACCGTTGTTCTGACTTCCAGCCTTGCCT
CATTCACCTGGATCCTCATCCCTGGGCCTTCCGCATCCTATTGGACTGACTGGTACTCCTGGGA
TATAATGCTCTGGCATTATTTTTATAGCAGAAGGTTGGGCTACTACACACGAGCTTCTGAAGTG
TGCCAATCTCTGTAGTTTCTGTTATGATCTTATGAGGCAGAAGCCAACGGGTGGAAAAAACAGT
AAAGATTCTGTGTAGCATGGAAATCAGCTGCAGCCCGTATCGTACATGGTACTGGGAATGTGGC
CTCATCACTTTAATTGCAGAGTTACTGGGAAACCATTTTCCCACTTGTGGGCGAAGATTCATTC
TTAGGAATGTCCAGATATCATGTTCTGTCTACATCATGGACTTTGGCCTAGGAGAACGTATTAG
ACTGGCACGGCCCTGTCTTGCATTAAGCCTCTCAGCCTGTCTGTCTCAGGCTTCCTCTCAGACT
CTGGGAATGAACCTTCTCAGTCACTGGTGCCTTACTCTTTCTCCAGTTTCAGGAACTGACCACT
TTTCTGTTGTGTATACGAGAGGCTGCTGACAGAAGCTGATGTAGACTGTACCTGGATTTCACTT
GAATTTGTAAAATGTGTATTGCTCAAAAAAAATGTTTGCAAATATTTGCACATAGGGTCTTGCA
CTGCTCATTTCCAGTGGAGTGTGTTTGCACACTAAACACAGGTGGACCCCTTCAAAAGGCGGTG
GAATCGCTCAGAACAAAAGGATCAGTAGTAGGTAGGACTCTCATACCTCAGAGCTCTAGAGGAG
CCAGAACTGTGTCTGGAATGGCCTGTGTTGTGAGTGTCTTGGCTTCTAGGGAAGGCTGTGCTGG
GGTCAGGAAACTGCCTCTTCAGCAGGGGAGTGTCGTGGCTGGACTGTATTTGCTTTACATCAGA
CAGGGAGAGATAGGGACGTGGACACGTTTTACTTGCTCCCTGAGATAACAGAAGTACCCAGAAG
TCTCTGGAATCCCTGTCACATCTGCTTCGTGTTGCTATTTGAGGCAGCAGACTTTATTTCTATG
CTAGGTCCTCACTACTGCTCCCTTCAGGCTGGGGAAAGGGAACATTTTGTCTCCATTGAGACAT
GCTCAGATAATTATCTGTTGATCTTGCTAATAGAAACTCAGAAAAATATAGACATTTTCTCCTG
ACCCTGTTTGTGGTATGTGCTGGCACTTTAAGCTCTTCTAAGCTTCAATGGTGTCTCCCTTCTG
GGCAAAGATCTGAAATATGACTATAGCCGGGCTATTAATGGATTCTGCTTTAGAAGTTGCATTT
TAAAAAGTGTTTTAATTTTGTCCTTCCAAGAGATAATGACGAAAGAGAAATGTCTTCATGTGTG
CACACACCCTGGTCCTGCACTTGCATATACACACTTATACCCATACATGTGCACACACACACAC
TCCACATATGCAGAAAGAAATGTTCAGATTCCTTTGAGAGCTTCAATCAAGTAATCTCTCTGTA
TGTGCTGTCTGAAGTCTACAGATTGGAGCTGGAGAAGTGGCTTGGTGCTCAAGATCACTTGCTG
CTCTTGCAGGAGGCCCAAGATGTGATTTAGTTCCTACAACATCAGGCGGCTCACAACCACATGC
CTATAACTCTAGTCCTAGAGGTTCTGATGCTCTCTTCTGTCGTCCTAGGGCGTCTGAGTGTACA
CGCACACATGCACATGCGCGCGCGCGCACACACACACACACACACACACACATACACACACACA
CACACACACACACCACAAGCTGTTAACATATGTTAGTAGGCAGAACATTGCAGTTTGTTTAACC
GATGGCTAGGTTCTTGTTACTACGCCAATCACACACTTGAGATTATTTATTGATCAAGGCAAAG
CAATTAGTCATGTTTGGGTTTGCTTTTTTTGTTGATAAGATTGACAACGCATGCTTTTTAAATG
CCTTTTCCCCTTATTTTCGATGTCTCTGTCGGGACGGAAGTTGTCAGCTAAAGACATGAGCTGT
TGTATTGAAAGTGTACAGGCTGTAGACCTTCATTGCTGCTGACTTCACACAGTTTACAGGATTC
TCGTGGACACACCAGGTATTATTACAGAAATATCCCAGATCATGCACATAAACATTTTATGGGT
GCAAGAGTGTCACCTGTAGGAGTTTTAACCAAACTCCACTCCCCTGGTACCATGGAGACTCATC
TTACTATTTAGTTTAGTGACAGGAAATAATCCCAGCTCTGGGCTCTGCTGGAACTCACAAATTC
TTTCTGGTTGTCTGTTTTCAAAATAGATAGAATAAACATTGTTATGCCGTGGA

hide sequence

RefSeq Acc Id:

XM_039105436 ⟹ XP_038961364

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	88,001,951 - 88,083,688 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001073619	(Get FASTA)	NCBI Sequence Viewer
	XP_006234709	(Get FASTA)	NCBI Sequence Viewer
	XP_017447389	(Get FASTA)	NCBI Sequence Viewer
	XP_038961364	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	A1L1K1	(Get FASTA)	NCBI Sequence Viewer
	AAI29105	(Get FASTA)	NCBI Sequence Viewer
	EDL79626	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001073619 ⟸ NM_001080150

- UniProtKB:

A1L1K1 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MTRGLAPLLPIEFHKMGSFRRPRPRFMSSPLLSELPRFQAARQALQLSSNSAWNSVQTAVINVF
KGGGLQSNELYALNESIRRLLKSELGSFITDYFQNQLLAKGLSFVEEKIKQCEGDNRIEVLAEV
WDHFFTETLPTLQAIFYPVQGQELTIRQISLLGFRDLVLLKVKLGDLLLLSQSKLPSSVIQMLL
ILQSVHEPTGPSEGYLQLEELVKQVVSPFLGLSGDRSCSRPTHSLARRHSRVRPKVTVLNYASL
MTTVGRPLNEMVLTPLTEQEGEAYLEKCGSVRRHTVANAHSDIQLLAMATMMHSGLGEESGSED
KHLLLPPTFPPPHRQCSSEPSILDSPDEMELEDVASGSQEDSELNCASLS

hide sequence

RefSeq Acc Id:

XP_006234710 ⟸ XM_006234648

- Peptide Label:

isoform X1

- Sequence:

show sequence

MTRGLAPLLPIEFHKMGSFRRPRPRFMSSPVLSELPRFQAARQALQLSSNSAWNSVQTAVINVF
KGGGLQSNELYALNESIRRLLKSELGSFITDYFQNQLLAKGLSFVEEKIKQCEGDNRIEVLAEV
WDHFFTETLPTLQAIFYPVQGQELTIRQISLLGFRDLVLLKVKLGDLLLLSQSKLPSSVIQMLL
ILQSVHEPTGPSEGYLQLEELVKQVVSPFLGLSGDRSCSRPTHSLARRHSRVRPKVTVLNYASL
MTTVGRPLNEMVLTPLTEQEGEAYLEKCGSVRRHTVANAHSDIQLLAMATMMHSGLGEESGSED
KHLLLPPTFPPPHRQCSSEPSILDSPDEMELEDVASGSQEDSELNCASLS

hide sequence

RefSeq Acc Id:	XP_006234709 ⟸ XM_006234647
- Peptide Label:	isoform X1
- UniProtKB:	F1LQP5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTRGLAPLLPIEFHKMGSFRRPRPRFMSSPVLSELPRFQAARQALQLSSNSAWNSVQTAVINVF KGGGLQSNELYALNESIRRLLKSELGSFITDYFQNQLLAKGLSFVEEKIKQCEGDNRIEVLAEV WDHFFTETLPTLQAIFYPVQGQELTIRQISLLGFRDLVLLKVKLGDLLLLSQSKLPSSVIQMLL ILQSVHEPTGPSEGYLQLEELVKQVVSPFLGLSGDRSCSRPTHSLARRHSRVRPKVTVLNYASL MTTVGRPLNEMVLTPLTEQEGEAYLEKCGSVRRHTVANAHSDIQLLAMATMMHSGLGEESGSED KHLLLPPTFPPPHRQCSSEPSILDSPDEMELEDVASGSQEDSELNCASLS hide sequence

RefSeq Acc Id:	XP_017447389 ⟸ XM_017591900
- Peptide Label:	isoform X1
- UniProtKB:	F1LQP5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTRGLAPLLPIEFHKMGSFRRPRPRFMSSPVLSELPRFQAARQALQLSSNSAWNSVQTAVINVF KGGGLQSNELYALNESIRRLLKSELGSFITDYFQNQLLAKGLSFVEEKIKQCEGDNRIEVLAEV WDHFFTETLPTLQAIFYPVQGQELTIRQISLLGFRDLVLLKVKLGDLLLLSQSKLPSSVIQMLL ILQSVHEPTGPSEGYLQLEELVKQVVSPFLGLSGDRSCSRPTHSLARRHSRVRPKVTVLNYASL MTTVGRPLNEMVLTPLTEQEGEAYLEKCGSVRRHTVANAHSDIQLLAMATMMHSGLGEESGSED KHLLLPPTFPPPHRQCSSEPSILDSPDEMELEDVASGSQEDSELNCASLS hide sequence

RefSeq Acc Id:

ENSRNOP00000006291 ⟸ ENSRNOT00000006291

RefSeq Acc Id:	XP_038961364 ⟸ XM_039105436
- Peptide Label:	isoform X1

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692244

Promoter ID:

EPDNEW_R2768

Type:

single initiation site

Name:

Prr5l_1

Description:

proline rich 5 like

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	91,370,173 - 91,370,233	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309969	AgrOrtholog
Ensembl Genes	ENSRNOG00000004666	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000006291	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000006291	ENTREZGENE, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7100178	IMAGE-MGC_LOAD
InterPro	Bit61/PRR5	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:362171	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:156710	IMAGE-MGC_LOAD
NCBI Gene	362171	ENTREZGENE
PANTHER	PTHR32428	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	HbrB	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Prr5l	PhenoGen
Transposagen	RGD1309969	Transposagen
UniProt	A1L1K1	ENTREZGENE
	F1LQP5	ENTREZGENE, UniProtKB/TrEMBL
	PRR5L_RAT	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-12-06	RGD1309969	similar to RIKEN cDNA 2600010E01	RGD1309969_predicted	similar to RIKEN cDNA 2600010E01 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1309969_predicted	similar to RIKEN cDNA 2600010E01 (predicted)	LOC362171_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC362171_predicted	similar to RIKEN cDNA 2600010E01 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

RGD Manual Annotations