Or4f54 (olfactory receptor family 4 subfamily F member 54) - Rat Genome Database

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Gene: Or4f54 (olfactory receptor family 4 subfamily F member 54) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or4f54
Name: olfactory receptor family 4 subfamily F member 54
RGD ID: 1585049
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC691368; olfactory receptor 4F15; rCG27146-like; similar to olfactory receptor 1278
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83118,361,533 - 118,362,471 (+)NCBIGRCr8
mRatBN7.2397,907,004 - 97,907,942 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl397,904,061 - 97,908,745 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.03102,510,339 - 102,511,282 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3102,510,339 - 102,511,277 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03109,109,421 - 109,110,359 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4396,875,377 - 96,884,409 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera396,912,291 - 96,913,193 (+)NCBICelera
Cytogenetic Map3q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or4f54Ratdetection of chemical stimulus involved in sensory perception of smell involved_inIEAGO:00049841600115GO_REF:0000108GOCGO_REF:0000108
Or4f54RatG protein-coupled receptor signaling pathway involved_inIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043
Or4f54RatG protein-coupled receptor signaling pathway involved_inIEAInterPro:IPR000276 and InterPro:IPR0007251600115GO_REF:0000002InterProGO_REF:0000002
Or4f54Ratsensory perception of smell involved_inIEAUniProtKB-KW:KW-05521600115GO_REF:0000043UniProtGO_REF:0000043
Or4f54Ratsignal transduction involved_inIEAUniProtKB-KW:KW-08071600115GO_REF:0000043UniProtGO_REF:0000043

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or4f54Ratmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
Or4f54Ratmembrane located_inIEAInterPro:IPR000276 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Or4f54Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Or4f54Ratplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044
Or4f54Ratplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or4f54RatG protein-coupled receptor activity enablesIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043
Or4f54RatG protein-coupled receptor activity enablesIEAInterPro:IPR0002761600115GO_REF:0000002InterProGO_REF:0000002
Or4f54Ratolfactory receptor activity enablesIEAInterPro:IPR0007251600115GO_REF:0000002InterProGO_REF:0000002
Or4f54Ratolfactory receptor activity enablesIBAMGI:3030568 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline


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Variants in Or4f54
2 total Variants

Predicted Target Of
Summary Value
Count of predictions:78
Count of miRNA genes:63
Interacting mature miRNAs:64
Transcripts:ENSRNOT00000074883
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 39 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582219Bw63Body weight QTL 633.80.001body mass (VT:0001259)body weight (CMO:0000012)396127817115665732Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)364655305115665732Rat

1 to 10 of 39 rows



endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
reproductive system
respiratory system
1 2 1 1 1 2 1 13 1



Ensembl Acc Id: ENSRNOT00000074883   ⟹   ENSRNOP00000065671
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl397,904,061 - 97,908,745 (+)Ensembl
Rnor_6.0 Ensembl3102,510,339 - 102,511,277 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101381   ⟹   ENSRNOP00000081788
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl397,904,061 - 97,908,745 (+)Ensembl
RefSeq Acc Id: NM_001409466   ⟹   NP_001396395
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83118,361,533 - 118,362,471 (+)NCBI
mRatBN7.2397,907,004 - 97,907,942 (+)NCBI
Protein RefSeqs NP_001396395 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL79775 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000065671.1
  ENSRNOP00000081788
  ENSRNOP00000081788.1
Ensembl Acc Id: ENSRNOP00000065671   ⟸   ENSRNOT00000074883
Ensembl Acc Id: ENSRNOP00000081788   ⟸   ENSRNOT00000101381
RefSeq Acc Id: NP_001396395   ⟸   NM_001409466
- UniProtKB: M0R879 (UniProtKB/TrEMBL),   A6HP24 (UniProtKB/TrEMBL)
G-protein coupled receptors family 1 profile

Name Modeler Protein Id AA Range Protein Structure
AF-M0R879-F1-model_v2 AlphaFold M0R879 1-312 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 26 of 26 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-48453 BioCyc
Ensembl Genes ENSRNOG00000048301 Ensembl
  ENSRNOG00000064719 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000085957 ENTREZGENE
Ensembl Transcript ENSRNOT00000074883.2 UniProtKB/TrEMBL
  ENSRNOT00000101381 ENTREZGENE
  ENSRNOT00000101381.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
  Olfactory_Receptors UniProtKB/TrEMBL
NCBI Gene 691368 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or4f54 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000048301 RatGTEx
  ENSRNOG00000064719 RatGTEx
  ENSRNOG00000085957 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A6HP24 ENTREZGENE, UniProtKB/TrEMBL
  M0R879 ENTREZGENE, UniProtKB/TrEMBL
1 to 26 of 26 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or4f54  olfactory receptor family 4 subfamily F member 54  LOC691368  similar to olfactory receptor 1278  Symbol and Name Changed 1299863 APPROVED
2013-05-24 LOC691368  similar to olfactory receptor 1278  LOC100364493  rCG27146-like  Data merged from RGD:2320967 1643240 APPROVED
2010-05-05 LOC100364493  rCG27146-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-01-09 LOC691368  similar to olfactory receptor 1278  LOC687802  similar to olfactory receptor 1278  Data merged from RGD:1596301 1643240 APPROVED
2006-11-20 LOC687802  similar to olfactory receptor 1278      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC691368  similar to olfactory receptor 1278      Symbol and Name status set to provisional 70820 PROVISIONAL