Kif18a (kinesin family member 18A)

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Gene: Kif18a (kinesin family member 18A) Rattus norvegicus

Analyze

Symbol:

Kif18a

Name:

kinesin family member 18A

RGD ID:

1561740

Description:

Predicted to enable several functions, including ATP hydrolysis activity; cytoskeletal protein binding activity; and plus-end-directed microtubule motor activity. Involved in cellular response to estradiol stimulus. Predicted to be located in several cellular components, including caveola; kinetochore microtubule; and ruffle. Predicted to be part of kinesin complex. Predicted to be active in mitotic spindle astral microtubule; mitotic spindle midzone; and nucleus. Orthologous to human KIF18A (kinesin family member 18A); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

kinesin-like protein KIF18A; LOC362186; RGD1561740; similar to Kinesin family member 18A

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	KIF18A (kinesin family member 18A)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Kif18a (kinesin family member 18A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Kif18a (kinesin family member 18A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	KIF18A (kinesin family member 18A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	KIF18A (kinesin family member 18A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Kif18a (kinesin family member 18A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	KIF18A (kinesin family member 18A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	KIF18A (kinesin family member 18A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Kif18a (kinesin family member 18A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Kif18a (kinesin family member 18A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	KIF18A (kinesin family member 18A)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	kif18a (kinesin family member 18A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	KIP3	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	Klp67A	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	95,764,388 - 95,824,756 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	95,764,388 - 95,824,582 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	99,327,315 - 99,387,814 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	3	107,926,278 - 107,986,777 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	3	105,687,071 - 105,747,262 (+)	NCBI	Rnor_WKY
Rnor_6.0	3	100,366,168 - 100,426,867 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	100,366,168 - 100,427,030 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	106,967,785 - 107,028,416 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	94,825,019 - 94,885,158 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	3	94,796,565 - 94,856,504 (+)	NCBI		Celera
Cytogenetic Map	3	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

colorectal cancer (ISO)

genetic disease (ISO)

hepatocellular carcinoma (ISO)

intellectual disability (ISO)

stomach cancer (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (EXP,ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-butoxyethanol (ISO)

3,4-methylenedioxymethamphetamine (ISO)

3-methylcholanthrene (EXP,ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrylamide (EXP,ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amphetamine (EXP)

arsenite(3-) (ISO)

azathioprine (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-ethylhexyl) phthalate (EXP)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

buta-1,3-diene (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

calcitriol (ISO)

cefaloridine (EXP)

choline (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

coumestrol (ISO)

CU-O LINKAGE (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

dicrotophos (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

Enterolactone (ISO)

ethanol (ISO)

folic acid (ISO)

furan (EXP)

gentamycin (EXP)

hydrogen peroxide (ISO)

hydroquinone (ISO)

L-methionine (ISO)

lead(0) (ISO)

lead(2+) (ISO)

leflunomide (ISO)

lidocaine (EXP)

N-Nitrosopyrrolidine (ISO)

ochratoxin A (ISO)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

PCB138 (ISO)

phenanthridone (ISO)

piroxicam (ISO)

potassium chromate (ISO)

propanal (ISO)

quercetin (ISO)

resveratrol (ISO)

rotenone (EXP)

SB 431542 (ISO)

senecionine (EXP)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

sophoraflavanone B (EXP)

sulforaphane (ISO)

sunitinib (ISO)

testosterone (ISO)

tetrachloromethane (ISO)

topotecan (EXP)

trichloroethene (EXP)

trichostatin A (ISO)

triclosan (ISO)

trimellitic anhydride (ISO)

trovafloxacin (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to estradiol stimulus (IEP)

male meiotic nuclear division (ISO)

microtubule depolymerization (IBA,ISO)

microtubule-based movement (IBA)

mitotic metaphase plate congression (ISO)

mitotic sister chromatid segregation (IBA)

regulation of microtubule cytoskeleton organization (ISO)

seminiferous tubule development (ISO)

Cellular Component

caveola (ISO)

cellular_component (ND)

cytoplasm (ISO)

kinesin complex (IBA)

kinetochore (ISO)

kinetochore microtubule (ISO)

microtubule cytoskeleton (ISO)

mitotic spindle astral microtubule (IBA)

mitotic spindle midzone (IBA,ISO)

nucleus (IBA,ISO)

ruffle (ISO)

Molecular Function

actin binding (ISO)

ATP binding (IEA)

ATP hydrolysis activity (IBA)

microtubule binding (IBA,ISO)

microtubule plus-end binding (ISO)

molecular_function (ND)

plus-end-directed microtubule motor activity (IBA,ISO)

protein binding (ISO)

tubulin-dependent ATPase activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Kinesin 18A expression: clinical relevance to colorectal cancer progression.	Nagahara M, etal., Int J Cancer. 2011 Dec 1;129(11):2543-52. doi: 10.1002/ijc.25916. Epub 2011 Jun 9.
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Comprehensive gene review and curation	RGD comprehensive gene curation
7.	[Expression of KIF18A in gastric cancer and its association with prognosis].	Wang L, etal., Zhonghua Wei Chang Wai Ke Za Zhi. 2016 May;19(5):585-9.
8.	The regulation of MS-KIF18A expression and cross talk with estrogen receptor.	Zusev M and Benayahu D, PLoS One. 2009 Jul 28;4(7):e6407. doi: 10.1371/journal.pone.0006407.

Additional References at PubMed

PMID:17006958	PMID:17346968	PMID:18680169	PMID:20981276

Genomics

Comparative Map Data

Kif18a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	95,764,388 - 95,824,756 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	95,764,388 - 95,824,582 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	99,327,315 - 99,387,814 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	3	107,926,278 - 107,986,777 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	3	105,687,071 - 105,747,262 (+)	NCBI	Rnor_WKY
Rnor_6.0	3	100,366,168 - 100,426,867 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	100,366,168 - 100,427,030 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	106,967,785 - 107,028,416 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	94,825,019 - 94,885,158 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	3	94,796,565 - 94,856,504 (+)	NCBI		Celera
Cytogenetic Map	3	q34	NCBI

KIF18A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	28,020,619 - 28,108,156 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	11	28,020,619 - 28,108,156 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	28,042,166 - 28,129,703 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	27,998,739 - 28,086,322 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	27,998,741 - 28,086,223	NCBI
Celera	11	28,188,055 - 28,275,612 (-)	NCBI		Celera
Cytogenetic Map	11	p14.1	NCBI
HuRef	11	27,740,692 - 27,828,542 (-)	NCBI		HuRef
CHM1_1	11	28,041,056 - 28,128,676 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	28,161,289 - 28,248,820 (-)	NCBI		T2T-CHM13v2.0

Kif18a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	109,111,083 - 109,172,094 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	109,111,083 - 109,172,092 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	109,280,738 - 109,341,749 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	109,280,738 - 109,341,747 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	109,120,895 - 109,181,904 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	109,081,577 - 109,142,586 (+)	NCBI		MGSCv36	mm8
Celera	2	110,441,710 - 110,502,913 (+)	NCBI		Celera
Cytogenetic Map	2	E3	NCBI

Kif18a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955476	7,058,573 - 7,109,610 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955476	7,058,682 - 7,117,496 (-)	NCBI	ChiLan1.0	ChiLan1.0

KIF18A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	11	27,890,317 - 27,976,429 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	27,888,435 - 27,976,429 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	11	27,989,506 - 28,076,078 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

KIF18A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	21	48,497,752 - 48,574,930 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	21	48,498,087 - 48,565,651 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	21	47,996,571 - 48,074,757 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	21	49,642,091 - 49,720,944 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	21	49,641,761 - 49,720,876 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	21	48,644,615 - 48,722,982 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	21	48,795,947 - 48,874,039 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	21	49,391,450 - 49,469,640 (-)	NCBI		UU_Cfam_GSD_1.0

Kif18a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	36,048,853 - 36,118,133 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936533	9,173,715 - 9,239,931 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936533	9,173,739 - 9,242,928 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KIF18A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	32,244,137 - 32,335,736 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	32,244,073 - 32,331,392 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	34,827,426 - 34,914,679 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KIF18A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	37,003,325 - 37,088,705 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	37,003,357 - 37,088,640 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	134,292,420 - 134,378,450 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Kif18a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624766	17,564,560 - 17,622,932 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624766	17,565,072 - 17,622,342 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Kif18a
303 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	301
Count of miRNA genes:	190
Interacting mature miRNAs:	217
Transcripts:	ENSRNOT00000006689
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	29463235	118376539	Rat
61419	Cia11	Collagen induced arthritis QTL 11	5.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	3	30356773	98535386	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	31172320	163586636	Rat
1354604	Bw36	Body weight QTL 36	2.9		body mass (VT:0001259)	body weight (CMO:0000012)	3	33703347	104104347	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	38192233	133483320	Rat
1354597	Kidm13	Kidney mass QTL 13	2.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	3	41874578	104104347	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	41874578	155617519	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	41874578	155617519	Rat
1581503	Cm58	Cardiac mass QTL 58	2.7	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	43827364	121056321	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	43827364	169034231	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	47233211	147415807	Rat
1358186	Ept2	Estrogen-induced pituitary tumorigenesis QTL 2	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	47233430	110362260	Rat
2292613	Ept16	Estrogen-induced pituitary tumorigenesis QTL 16	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	47233430	110362260	Rat
631665	Bw8	Body weight QTL 8	5.5		body mass (VT:0001259)	body weight (CMO:0000012)	3	50437042	119183768	Rat
724523	Tsu1	Thymus enlargement suppressive QTL 1	3.84		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	3	50437504	115638231	Rat
1582218	Bw74	Body weight QTL 74	3.9	0.0021	body mass (VT:0001259)	body weight (CMO:0000012)	3	53184593	115665732	Rat
1582238	Bw68	Body weight QTL 68	3.2	0.0064	body mass (VT:0001259)	body weight (CMO:0000012)	3	53184593	115665732	Rat
1582239	Epfw1	Epididymal fat weight QTL 1	4.5	0.0006	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	3	53184593	115665732	Rat
1581568	Rf53	Renal function QTL 53			urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	3	56395968	161299569	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	59242096	157323038	Rat
1300111	Rf12	Renal function QTL 12	3.78		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	61017749	121056321	Rat
1582210	Bw71	Body weight QTL 71	3.3	0.0012	body mass (VT:0001259)	body weight (CMO:0000012)	3	64655305	115665732	Rat
1582221	Kidm30	Kidney mass QTL 30	3.5	0.0008	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	3	64655305	115665732	Rat
12879848	Bw181	Body weght QTL 181		0.015	body mass (VT:0001259)	body weight (CMO:0000012)	3	70348525	121056321	Rat
2301414	Kidm37	Kidney mass QTL 37		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	70653097	121056321	Rat
1600376	Arunc5	Aerobic running capacity QTL 5		0.21	exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	3	73376539	118376539	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	78196190	146592722	Rat
2302273	Gluco35	Glucose level QTL 35	5.3	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	80800231	114297550	Rat
631649	Bp123	Blood pressure QTL 123	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	89772419	134772419	Rat
8694437	Bw167	Body weight QTL 167	22.46	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	3	91797474	136797474	Rat
631841	Niddm39	Non-insulin dependent diabetes mellitus QTL 39	3.36		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	94856903	159898684	Rat
724532	Cm17	Cardiac mass QTL 17	2		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	3	95735366	140735366	Rat

Markers in Region

RH132762

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	95,775,394 - 95,775,906 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	100,377,206 - 100,377,717	NCBI	Rnor6.0
Rnor_5.0	3	106,978,935 - 106,979,446	UniSTS	Rnor5.0
RGSC_v3.4	3	94,835,972 - 94,836,483	UniSTS	RGSC3.4
Celera	3	94,807,327 - 94,807,838	UniSTS
RH 3.4 Map	3	755.6	UniSTS
Cytogenetic Map	3	q33	UniSTS

RH134079

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	95,824,402 - 95,824,622 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	100,426,508 - 100,426,727	NCBI	Rnor6.0
Rnor_5.0	3	107,028,237 - 107,028,456	UniSTS	Rnor5.0
RGSC_v3.4	3	94,884,979 - 94,885,198	UniSTS	RGSC3.4
Celera	3	94,856,325 - 94,856,544	UniSTS
RH 3.4 Map	3	753.6	UniSTS
Cytogenetic Map	3	q33	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium		6	24	18	12	18			28	14	28
Low	3	29	28	18	7	18	4	4	37	20	13	11	4
Below cutoff		7	5	5		5	4	6	9	1			4

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001137642	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017591907	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017591908	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105450	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105451	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105452	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105453	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000118	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000006689 ⟹ ENSRNOP00000006689

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	95,764,388 - 95,824,582 (+)	Ensembl
Rnor_6.0 Ensembl	3	100,366,168 - 100,426,687 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000085176 ⟹ ENSRNOP00000069771

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	95,764,470 - 95,824,397 (+)	Ensembl
Rnor_6.0 Ensembl	3	100,373,439 - 100,427,030 (+)	Ensembl

RefSeq Acc Id:

NM_001137642 ⟹ NP_001131114

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	95,764,388 - 95,824,582 (+)	NCBI
Rnor_6.0	3	100,366,168 - 100,426,687 (+)	NCBI
Rnor_5.0	3	106,967,785 - 107,028,416 (+)	NCBI
RGSC_v3.4	3	94,825,019 - 94,885,158 (+)	RGD
Celera	3	94,796,565 - 94,856,504 (+)	RGD

Sequence:

show sequence

GCGAGACGCCGGGGAAAACGACCGACGTGCTGACGTCAGCCGATCGGCAGCCAATGAAATGGAT
AGCTGAGGAAGCTGGCTTGGGTTTGAATTTGTGGCTGTGTTTGGAGCGCCTGGAAGCCAACTCA
GCCAAGTTGTCGCGGTCACTTCTAGTATTTGCATATGGTGCCACTGGATCTGGGAAGACTCACA
CAATGCTGGGATCAACTGCTGAACCCGGGGTCATGTACCTAACAATGCTGGACCTTTTCAAATG
CATGGATGAGGTTAAAGACGAGAAAGAGTGTAGTACTGCAGTCTCTTATCTGGAGGTATATAAT
GAACAGATTCGTGACCTCTTGACAAACTCAGGGCCACTTGCTGTCCGGGAAGATGCCCAAAAAG
GAGTGGTTGTTCAGGGTCTTACTCTACACCAGCCTAAATCTTCAGAGGAAATATTGCAGCTACT
AGACAATGGAAACAAAAACAGGACGCAGCATCCCACTGACATGAATGCTGCGTCTTCTCGTTCT
CATGCTGTTTTCCAGATTTATTTACGACAACAGGACAAAACAGCAAGCATCAATCAAAATGTCC
ATATAGCCAAAATGTCACTCATTGACCTCGCAGGATCTGAGCGGGCCAGTATTTCTGGTACTAA
AGGGACAAGATTTGTAGAAGGCACAAATATTAACAAATCTCTTCTAGCTCTTGGGAATGTCATC
AATGCCTTAGCAGATACAAAGAGAAGAAATCAGCATATTCCTTACAGAAATAGTAAACTTACTC
GTTTGCTGAAGGATTCTCTTGGAGGAAACTGTCAAACTATAATGATAGCTGCTGTTAGTCCTTC
CTCTTTATTCTACGATGACACATATAACACTCTTAAGTACGCAAATCGTGCCAAAGACATTAAG
TCTTCTCAGTTGAAGAGCAATGTTGTCAACCTCAGTAGTCACATATCACAGTATGTAAAGATCT
GCAACATGCAGAAGGCAGAGATTTTAATGTTGAAAGAGAAACTAAAGGCCTATGAAGGACAGAA
AGCTCTGACTGACAGAAATGACTGTGCTAAATTAGTACATTCAAACGTGGAGGACAAAGAGATT
GAAAGATTTCAAGAAATTCTGAACTGCTTGTTCCAGAATCGAGAAGGAATGAGGCAAGAATATC
TGAAGGTAGAAATGTTACTTAAAGAAAATGAACTAAAGTCATCCTATCATCAACAGTGCCATAA
GCAAATAGAAATGATGTGTTCTGAGGACAAATTGGAAAAGGCCACTTGCAGACGAGATCACAGA
CTTGAAAAGTTGAAAAGCAACCGCTGTGTGCTAGAGAAAAAGAAAGAAGAGATGTTGAAACAGT
TTGATGAAAATACTAATTGGCTACATCGAGTGGAAAGTGAAATGCGACTCTTAGGTCAAAATGG
TGATATTCCCGAGGGACTCAATAAAGATCTTCATTGTCACCATTTACACCTCCAAAACAAAGAC
CTGAAAACACAAATGGGACACATGATGACTCTGGCTGCTCTCCAGGAGCAGCAGCATGGGCAGA
CTGAAGCAGTACTGAATGCTTTGCTTCCAGTCCTAAGAAAACAGTATTGGAGATTGAAAGAAAC
CGGCCTGTCAAACGCTGCTTTTGATTCTGACTTCAAAGATATTGAACATTTAGTAGAGAGAAAA
AAGGTAGTGGCTTGGGCTGACCAAACTGCTGAACATTCAAACCAAAGTGATGTTCCTGGTACTT
CTCTTCTTATGACCTTCCCACAGCTTGGACCAATTCAGTCTATTCCTTGTTGCTCATCCATGAG
TGACCCTAGCATACTTAAGATTACTCCACAAAGAAGAACCAAAAGAAAATTAATACCTTCTCCA
TTGAAAGTAAAACATACTCAGAAGTCTGCACTGTCTGAAAGGACACAGCTTAATGATTCTTTTA
GCAAAGAACTTCAGCCTATTGTTTACACCCCAGAGGACAGCAGAAGAACTGTTCAGGACCTCTC
TCCACCCTTAGCAAGAGCGTCCTCACATTCTGCAAATGGAATGAATGATAATTCCCTGAAAGCA
CTGTGTAGAACAGAATCTCCTCTCAGCAGAACCGAGTGTAAAGAGGGTTTGTACTCTACATCTG
CTATATGTGATGGTATCAAAAGCTTGAAAAATAATTTGCCTGAACCACTACCGAGCAGCAAAAG
CACTTTACACAGGGTGGAGTCTTCCTCATTTCCAACGAAGGATTCTAGGTCTGTATCAACAAGT
GTGCCATCCTACATGGCGATGACCACTGCTGCAAAGAGGAAGTGGAAATTCATGAGTTCTACAT
CAGATGCTTCATTAAAATCTGATGAAAGTTGTGGACTTGCCAAACGCATTCGACAGGATAATTC
AAGTGTTAAGCTCATCCGAGAAAACAGACTGAGAGTGGGCTATAAAAAAACCACCAACAAAACA
AATTCAAACATGCTTAGAAAATTTAGAAGAAACACTTCAAAAGAAAATGTACAATAAGAAGAAT
CAATGTCCTTTGTATGGTATTTGTTTCTTCAGAAATGTATTTCAAGTCTGTGAAAGGAGACCAT
CTAAAACTGTTTGCTCAAATATTTTCAGCAGCAAAATGAGACTTTTGTATTTAAAATAAATATA
AAATTACAACAGGGTATGTTTCCCATTTCTCAGATATTTGGTACTCTTGAAAATCTCTCTAAGT
CACCATGATGCCAATTTACTTGTACTTTACCAGAACTTGATTGGAACATTGTAGAAAAAATAGA
AAATTAAACTGCCCTTATTATTTTCAAAAATAAAGAGACTTTAGAAGTCATAGTTATGGCCAAG
ATGTTTTGGTCTTCTGCTGTGTGTCAATATGTTGGTATATTCATACACGTGATTTTACTTTCTA
AAATTTTGGTGTAAAAATGTAGATATATATCCATAACATTGTAAATATTGTTTAAATACTCACC
ATAAATAATATGGTAATATTTTATTACTTGGTATATTAAAGATGTAGATTTTAAATA

hide sequence

RefSeq Acc Id:

XM_017591908 ⟹ XP_017447397

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	95,764,405 - 95,824,756 (+)	NCBI
Rnor_6.0	3	100,373,224 - 100,426,867 (+)	NCBI

Sequence:

show sequence

AGAAATAGCCCGCGTCTTCATCGTAACAGGAATTGAGGGTAACTAAATGTATCTGGACTGAGGA
GGACTTATGTCACCACATGAAAGTAGTGTCCGTGTCCGTCCGAGAACCACAAAAGAAAAGGGCT
GATCAGTTACATAGAAGGTTCATGGTAGTGGATATAGCATATACTCGTTTTGATCCGAAACAAG
AAGAAAATCAAGTTTTTTCACAGAAAAAAAACTCAAATTTTGATATTACTAAAGGCAAAATAAA
GATCTTTAAGTTTGTCATTTGATGCTGTTTTGATGAAACCTCAACTCAAATGGAAGTTTTTGAA
CACACAACCAAGCCAATTCTCATAGTTTTCTGAATGGATATAATTGCACAGTATTTGCATATGG
TGCCACTGGATCTGGGAAGACTCACACAATGCTGGGATCAACTGCTGAACCCGGGGTCATGTAC
CTAACAATGCTGGACCTTTTCAAATGCATGGATGAGGTTAAAGACGAGAAAGAGTGTAGTACTG
CAGTCTCTTATCTGGAGGTATATAATGAACAGATTCGTGACCTCTTGACAAACTCAGGGCCACT
TGCTGTCCGGGAAGATGCCCAAAAAGGAGTGGTTGTTCAGGGTCTTACTCTACACCAGCCTAAA
TCTTCAGAGGAAATATTGCAGCTACTAGACAATGGAAACAAAAACAGGACGCAGCATCCCACTG
ACATGAATGCTGCGTCTTCTCGTTCTCATGCTGTTTTCCAGATTTATTTACGACAACAGGACAA
AACAGCAAGCATCAATCAAAATGTCCATATAGCCAAAATGTCACTCATTGACCTCGCAGGATCT
GAGCGGGCCAGTATTTCTGGTACTAAAGGGACAAGATTTGTAGAAGGCACAAATATTAACAAAT
CTCTTCTAGCTCTTGGGAATGTCATCAATGCCTTAGCAGATACAAAGAGAAGAAATCAGCATAT
TCCTTACAGAAATAGTAAACTTACTCGTTTGCTGAAGGATTCTCTTGGAGGAAACTGTCAAACT
ATAATGATAGCTGCTGTTAGTCCTTCCTCTTTATTCTACGATGACACATATAACACTCTTAAGT
ACGCAAATCGTGCCAAAGACATTAAGTCTTCTTTGAAGAGCAATGTTGTCAACCTCAGTAGTCA
CATATCACAGTATGTAAAGATCTGCAACATGCAGAAGGCAGAGATTTTAATGTTGAAAGAGAAA
CTAAAGGCCTATGAAGGACAGAAAGCTCTGACTGACAGAAATGACTGTGCTAAATTAGTACATT
CAAACGTGGAGGACAAAGAGATTGAAAGATTTCAAGAAATTCTGAACTGCTTGTTCCAGAATCG
AGAAGGAATGAGGCAAGAATATCTGAAGGTAGAAATGTTACTTAAAGAAAATGAACTAAAGTCA
TCCTATCATCAACAGTGCCATAAGCAAATAGAAATGATGTGTTCTGAGGACAAATTGGAAAAGG
CCACTTGCAGACGAGATCACAGACTTGAAAAGTTGAAAAGCAACCGCTGTGTGCTAGAGAAAAA
GAAAGAAGAGATGTTGAAACAGTTTGATGAAAATACTAATTGGCTACATCGAGTGGAAAGTGAA
ATGCGACTCTTAGGTCAAAATGGTGATATTCCCGAGGGACTCAATAAAGATCTTCATTGTCACC
ATTTACACCTCCAAAACAAAGACCTGAAAACACAAATGGGACACATGATGACTCTGGCTGCTCT
CCAGGAGCAGCAGCATGGGCAGACTGAAGCAGTACTGAATGCTTTGCTTCCAGTCCTAAGAAAA
CAGTATTGGAGATTGAAAGAAACCGGCCTGTCAAACGCTGCTTTTGATTCTGACTTCAAAGATA
TTGAACATTTAGTAGAGAGAAAAAAGGTAGTGGCTTGGGCTGACCAAACTGCTGAACATTCAAA
CCAAAGTGATGTTCCTGGTACTTCTCTTCTTATGACCTTCCCACAGCTTGGACCAATTCAGTCT
ATTCCTTGTTGCTCATCCATGAGTGACCCTAGCATACTTAAGATTACTCCACAAAGAAGAACCA
AAAGAAAATTAATACCTTCTCCATTGAAAGTAAAACATACTCAGAAGTCTGCACTGTCTGAAAG
GACACAGCTTAATGATTCTTTTAGCAAAGAACTTCAGCCTATTGTTTACACCCCAGAGGACAGC
AGAAGAACTGTTCAGGACCTCTCTCCACCCTTAGCAAGAGCGTCCTCACATTCTGCAAATGGAA
TGAATGATAATTCCCTGAAAGCACTGTGTAGAACAGAATCTCCTCTCAGCAGAACCGAGTGTAA
AGAGGGTTTGTACTCTACATCTGCTATATGTGATGGTATCAAAAGCTTGAAAAATAATTTGCCT
GAACCACTACCGAGCAGCAAAAGCACTTTACACAGGGTGGAGTCTTCCTCATTTCCAACGAAGG
ATTCTAGGTCTGTATCAACAAGTGTGCCATCCTACATGGCGATGACCACTGCTGCAAAGAGGAA
GTGGAAATTCATGAGTTCTACATCAGATGCTTCATTAAAATCTGATGAAAGTTGTGGACTTGCC
AAACGCATTCGACAGGATAATTCAAGTGTTAAGCTCATCCGAGAAAACAGACTGAGAGTGGGCT
ATAAAAAAACCACCAACAAAACAAATTCAAACATGCTTAGAAAATTTAGAAGAAACACTTCAAA
AGAAAATGTACAATAAGAAGAATCAATGTCCTTTGTATGGTATTTGTTTCTTCAGAAATGTATT
TCAAGTCTGTGAAAGGAGACCATCTAAAACTGTTTGCTCAAATATTTTCAGCAGCAAAATGAGA
CTTTTGTATTTAAAATAAATATAAAATTACAACAGGGTATGTTTCCCATTTCTCAGATATTTGG
TACTCTTGAAAATCTCTCTAAGTCACCATGATGCCAATTTACTTGTACTTTACCAGAACTTGAT
TGGAACATTGTAGAAAAAATAGAAAATTAAACTGCCCTTATTATTTTCAAAAATAAAGAGACTT
TAGAAGTCATAGTTATGGCCAAGATGTTTTGGTCTTCTGCTGTGTGTCAATATGTTGGTATATT
CATACACGTGATTTTACTTTCTAAAATTTTGGTGTAAAAATGTAGATATATATCCATAACATTG
TAAATATTGTTTAAATACTCACCATAAATAATATGGTAATATTTTATTACTTGGTATATTAAAG
ATGTAGATTTTAAATAGTTTGTTTTTCCTGTTTTATTGCAATCCCTTATATGCTCTAAATGTTA
TTTTATATAAGCATGAGTTTTGTAAATTTGTTTTTCCTATCTTGTTCCTATGGGACCATTGTGT
ACCTAGACCAAATTTGTAAACAATCCATAGGTTTCTTAATAAATAGAAATGGTGAGAAAGCATT
TTAA

hide sequence

RefSeq Acc Id:

XM_039105450 ⟹ XP_038961378

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	95,764,405 - 95,824,756 (+)	NCBI

RefSeq Acc Id:

XM_039105451 ⟹ XP_038961379

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	95,764,417 - 95,824,756 (+)	NCBI

RefSeq Acc Id:

XM_039105452 ⟹ XP_038961380

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	95,764,452 - 95,824,756 (+)	NCBI

RefSeq Acc Id:

XM_039105453 ⟹ XP_038961381

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	95,764,577 - 95,824,756 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001131114	(Get FASTA)	NCBI Sequence Viewer
	XP_017447397	(Get FASTA)	NCBI Sequence Viewer
	XP_038961378	(Get FASTA)	NCBI Sequence Viewer
	XP_038961379	(Get FASTA)	NCBI Sequence Viewer
	XP_038961380	(Get FASTA)	NCBI Sequence Viewer
	XP_038961381	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL79750	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001131114 ⟸ NM_001137642

- UniProtKB:

D3ZIA5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MKWIAEEAGLGLNLWLCLERLEANSAKLSRSLLVFAYGATGSGKTHTMLGSTAEPGVMYLTMLD
LFKCMDEVKDEKECSTAVSYLEVYNEQIRDLLTNSGPLAVREDAQKGVVVQGLTLHQPKSSEEI
LQLLDNGNKNRTQHPTDMNAASSRSHAVFQIYLRQQDKTASINQNVHIAKMSLIDLAGSERASI
SGTKGTRFVEGTNINKSLLALGNVINALADTKRRNQHIPYRNSKLTRLLKDSLGGNCQTIMIAA
VSPSSLFYDDTYNTLKYANRAKDIKSSQLKSNVVNLSSHISQYVKICNMQKAEILMLKEKLKAY
EGQKALTDRNDCAKLVHSNVEDKEIERFQEILNCLFQNREGMRQEYLKVEMLLKENELKSSYHQ
QCHKQIEMMCSEDKLEKATCRRDHRLEKLKSNRCVLEKKKEEMLKQFDENTNWLHRVESEMRLL
GQNGDIPEGLNKDLHCHHLHLQNKDLKTQMGHMMTLAALQEQQHGQTEAVLNALLPVLRKQYWR
LKETGLSNAAFDSDFKDIEHLVERKKVVAWADQTAEHSNQSDVPGTSLLMTFPQLGPIQSIPCC
SSMSDPSILKITPQRRTKRKLIPSPLKVKHTQKSALSERTQLNDSFSKELQPIVYTPEDSRRTV
QDLSPPLARASSHSANGMNDNSLKALCRTESPLSRTECKEGLYSTSAICDGIKSLKNNLPEPLP
SSKSTLHRVESSSFPTKDSRSVSTSVPSYMAMTTAAKRKWKFMSSTSDASLKSDESCGLAKRIR
QDNSSVKLIRENRLRVGYKKTTNKTNSNMLRKFRRNTSKENVQ

hide sequence

RefSeq Acc Id:

XP_017447397 ⟸ XM_017591908

- Peptide Label:

isoform X2

- Sequence:

show sequence

MLGSTAEPGVMYLTMLDLFKCMDEVKDEKECSTAVSYLEVYNEQIRDLLTNSGPLAVREDAQKG
VVVQGLTLHQPKSSEEILQLLDNGNKNRTQHPTDMNAASSRSHAVFQIYLRQQDKTASINQNVH
IAKMSLIDLAGSERASISGTKGTRFVEGTNINKSLLALGNVINALADTKRRNQHIPYRNSKLTR
LLKDSLGGNCQTIMIAAVSPSSLFYDDTYNTLKYANRAKDIKSSLKSNVVNLSSHISQYVKICN
MQKAEILMLKEKLKAYEGQKALTDRNDCAKLVHSNVEDKEIERFQEILNCLFQNREGMRQEYLK
VEMLLKENELKSSYHQQCHKQIEMMCSEDKLEKATCRRDHRLEKLKSNRCVLEKKKEEMLKQFD
ENTNWLHRVESEMRLLGQNGDIPEGLNKDLHCHHLHLQNKDLKTQMGHMMTLAALQEQQHGQTE
AVLNALLPVLRKQYWRLKETGLSNAAFDSDFKDIEHLVERKKVVAWADQTAEHSNQSDVPGTSL
LMTFPQLGPIQSIPCCSSMSDPSILKITPQRRTKRKLIPSPLKVKHTQKSALSERTQLNDSFSK
ELQPIVYTPEDSRRTVQDLSPPLARASSHSANGMNDNSLKALCRTESPLSRTECKEGLYSTSAI
CDGIKSLKNNLPEPLPSSKSTLHRVESSSFPTKDSRSVSTSVPSYMAMTTAAKRKWKFMSSTSD
ASLKSDESCGLAKRIRQDNSSVKLIRENRLRVGYKKTTNKTNSNMLRKFRRNTSKENVQ

hide sequence

RefSeq Acc Id:

ENSRNOP00000006689 ⟸ ENSRNOT00000006689

RefSeq Acc Id:

ENSRNOP00000069771 ⟸ ENSRNOT00000085176

RefSeq Acc Id:	XP_038961378 ⟸ XM_039105450
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2JW74 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038961379 ⟸ XM_039105451
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2JW74 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038961380 ⟸ XM_039105452
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2JW74 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038961381 ⟸ XM_039105453
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2JW74 (UniProtKB/TrEMBL)

Protein Domains

Kinesin motor

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZIA5-F1-model_v2	AlphaFold	D3ZIA5	1-811	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692277

Promoter ID:

EPDNEW_R2802

Type:

initiation region

Name:

Kif18a_1

Description:

kinesin family member 18A

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	100,366,220 - 100,366,280	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1561740	AgrOrtholog
BioCyc Gene	G2FUF-48483	BioCyc
Ensembl Genes	ENSRNOG00000005037	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000006689	ENTREZGENE
	ENSRNOP00000006689.5	UniProtKB/TrEMBL
	ENSRNOP00000069771	ENTREZGENE
	ENSRNOP00000069771.2	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000006689	ENTREZGENE
	ENSRNOT00000006689.7	UniProtKB/TrEMBL
	ENSRNOT00000085176	ENTREZGENE
	ENSRNOT00000085176.2	UniProtKB/TrEMBL
Gene3D-CATH	3.40.850.10	UniProtKB/TrEMBL
InterPro	Kinesin-like_fam	UniProtKB/TrEMBL
	Kinesin_motor_CS	UniProtKB/TrEMBL
	Kinesin_motor_dom	UniProtKB/TrEMBL
	Kinesin_motor_dom_sf	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
KEGG Report	rno:362186	UniProtKB/TrEMBL
NCBI Gene	362186	ENTREZGENE
PANTHER	CENTROMERE PROTEIN E	UniProtKB/TrEMBL
	KINESIN-LIKE PROTEIN	UniProtKB/TrEMBL
Pfam	Kinesin	UniProtKB/TrEMBL
PhenoGen	Kif18a	PhenoGen
PRINTS	KINESINHEAVY	UniProtKB/TrEMBL
PROSITE	KINESIN_MOTOR_DOMAIN1	UniProtKB/TrEMBL
	KINESIN_MOTOR_DOMAIN2	UniProtKB/TrEMBL
SMART	KISc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	A0A0G2JW74	ENTREZGENE, UniProtKB/TrEMBL
	D3ZIA5	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-02-29	Kif18a	kinesin family member 18A	RGD1561740_predicted	similar to Kinesin family member 18A (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1561740_predicted	similar to Kinesin family member 18A (predicted)	LOC362186	similar to Kinesin family member 18A	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC362186	similar to Kinesin family member 18A			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD