Kif18a (kinesin family member 18A) - Rat Genome Database

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Gene: Kif18a (kinesin family member 18A) Rattus norvegicus
Analyze
Symbol: Kif18a
Name: kinesin family member 18A
RGD ID: 1561740
Description: Predicted to enable several functions, including ATP hydrolysis activity; cytoskeletal protein binding activity; and plus-end-directed microtubule motor activity. Involved in cellular response to estradiol stimulus. Predicted to be located in several cellular components, including caveola; kinetochore microtubule; and ruffle. Predicted to be part of kinesin complex. Predicted to be active in mitotic spindle astral microtubule; mitotic spindle midzone; and nucleus. Orthologous to human KIF18A (kinesin family member 18A); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: kinesin-like protein KIF18A; LOC362186; RGD1561740; similar to Kinesin family member 18A
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83116,219,007 - 116,279,378 (+)NCBIGRCr8
mRatBN7.2395,764,388 - 95,824,756 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl395,764,388 - 95,824,582 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx399,327,315 - 99,387,814 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03107,926,278 - 107,986,777 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03105,687,071 - 105,747,262 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03100,366,168 - 100,426,867 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3100,366,168 - 100,427,030 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03106,967,785 - 107,028,416 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4394,825,019 - 94,885,158 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera394,796,565 - 94,856,504 (+)NCBICelera
Cytogenetic Map3q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-butoxyethanol  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-methylcholanthrene  (EXP,ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
amphetamine  (EXP)
arsenite(3-)  (ISO)
azathioprine  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buta-1,3-diene  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
cefaloridine  (EXP)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
CU-O LINKAGE  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
ethanol  (ISO)
folic acid  (ISO)
FR900359  (ISO)
furan  (EXP)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
leflunomide  (ISO)
lidocaine  (EXP)
methimazole  (EXP)
N-Nitrosopyrrolidine  (ISO)
ochratoxin A  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorooctanoic acid  (ISO)
phenanthridone  (ISO)
piroxicam  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
propanal  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
senecionine  (EXP)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sophoraflavanone B  (EXP)
sulfadimethoxine  (EXP)
sulforaphane  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thiram  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
trovafloxacin  (ISO)
valproic acid  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Kinesin 18A expression: clinical relevance to colorectal cancer progression. Nagahara M, etal., Int J Cancer. 2011 Dec 1;129(11):2543-52. doi: 10.1002/ijc.25916. Epub 2011 Jun 9.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. [Expression of KIF18A in gastric cancer and its association with prognosis]. Wang L, etal., Zhonghua Wei Chang Wai Ke Za Zhi. 2016 May;19(5):585-9.
8. The regulation of MS-KIF18A expression and cross talk with estrogen receptor. Zusev M and Benayahu D, PLoS One. 2009 Jul 28;4(7):e6407. doi: 10.1371/journal.pone.0006407.
Additional References at PubMed
PMID:17006958   PMID:17346968   PMID:18680169   PMID:20981276  


Genomics

Comparative Map Data
Kif18a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83116,219,007 - 116,279,378 (+)NCBIGRCr8
mRatBN7.2395,764,388 - 95,824,756 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl395,764,388 - 95,824,582 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx399,327,315 - 99,387,814 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03107,926,278 - 107,986,777 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03105,687,071 - 105,747,262 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03100,366,168 - 100,426,867 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3100,366,168 - 100,427,030 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03106,967,785 - 107,028,416 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4394,825,019 - 94,885,158 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera394,796,565 - 94,856,504 (+)NCBICelera
Cytogenetic Map3q34NCBI
KIF18A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381128,020,619 - 28,108,156 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1128,020,619 - 28,108,156 (-)EnsemblGRCh38hg38GRCh38
GRCh371128,042,166 - 28,129,703 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361127,998,739 - 28,086,322 (-)NCBINCBI36Build 36hg18NCBI36
Build 341127,998,741 - 28,086,223NCBI
Celera1128,188,055 - 28,275,612 (-)NCBICelera
Cytogenetic Map11p14.1NCBI
HuRef1127,740,692 - 27,828,542 (-)NCBIHuRef
CHM1_11128,041,056 - 28,128,676 (-)NCBICHM1_1
T2T-CHM13v2.01128,161,289 - 28,248,842 (-)NCBIT2T-CHM13v2.0
Kif18a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392109,111,165 - 109,172,094 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2109,111,083 - 109,172,092 (+)EnsemblGRCm39 Ensembl
GRCm382109,280,738 - 109,341,749 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2109,280,738 - 109,341,747 (+)EnsemblGRCm38mm10GRCm38
MGSCv372109,120,895 - 109,181,904 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362109,081,577 - 109,142,586 (+)NCBIMGSCv36mm8
Celera2110,441,710 - 110,502,913 (+)NCBICelera
Cytogenetic Map2E3NCBI
cM Map256.55NCBI
Kif18a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554767,058,573 - 7,109,610 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554767,058,682 - 7,117,496 (-)NCBIChiLan1.0ChiLan1.0
KIF18A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2930,234,673 - 30,322,407 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11130,236,640 - 30,323,236 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01127,989,506 - 28,076,078 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11127,890,317 - 27,976,429 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1127,888,435 - 27,976,429 (-)Ensemblpanpan1.1panPan2
KIF18A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12148,497,752 - 48,574,930 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2148,498,087 - 48,565,651 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2147,996,571 - 48,074,757 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02149,642,091 - 49,720,944 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2149,641,761 - 49,720,876 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12148,644,615 - 48,722,982 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02148,795,947 - 48,874,039 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02149,391,450 - 49,469,640 (-)NCBIUU_Cfam_GSD_1.0
Kif18a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494736,048,853 - 36,118,133 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365339,173,715 - 9,239,931 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365339,173,739 - 9,242,928 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KIF18A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl232,244,137 - 32,335,736 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1232,244,073 - 32,331,392 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2234,827,426 - 34,914,679 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KIF18A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1137,003,325 - 37,088,705 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl137,003,357 - 37,088,640 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038134,292,420 - 134,378,450 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kif18a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476617,564,560 - 17,622,932 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476617,565,072 - 17,622,342 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Kif18a
306 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:301
Count of miRNA genes:190
Interacting mature miRNAs:217
Transcripts:ENSRNOT00000006689
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)364655305115665732Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)364655305115665732Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)373376539118376539Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)391797474136797474Rat
2302273Gluco35Glucose level QTL 355.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)380800231114297550Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)389772419134772419Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)33035677398535386Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)341874578104104347Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)395735366140735366Rat

Markers in Region
RH132762  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2395,775,394 - 95,775,906 (+)MAPPERmRatBN7.2
Rnor_6.03100,377,206 - 100,377,717NCBIRnor6.0
Rnor_5.03106,978,935 - 106,979,446UniSTSRnor5.0
RGSC_v3.4394,835,972 - 94,836,483UniSTSRGSC3.4
Celera394,807,327 - 94,807,838UniSTS
RH 3.4 Map3755.6UniSTS
Cytogenetic Map3q33UniSTS
RH134079  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2395,824,402 - 95,824,622 (+)MAPPERmRatBN7.2
Rnor_6.03100,426,508 - 100,426,727NCBIRnor6.0
Rnor_5.03107,028,237 - 107,028,456UniSTSRnor5.0
RGSC_v3.4394,884,979 - 94,885,198UniSTSRGSC3.4
Celera394,856,325 - 94,856,544UniSTS
RH 3.4 Map3753.6UniSTS
Cytogenetic Map3q33UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 6 24 18 12 18 28 14 28
Low 3 29 28 18 7 18 4 4 37 20 13 11 4
Below cutoff 7 5 5 5 4 6 9 1 4

Sequence


RefSeq Acc Id: ENSRNOT00000006689   ⟹   ENSRNOP00000006689
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl395,764,388 - 95,824,582 (+)Ensembl
Rnor_6.0 Ensembl3100,366,168 - 100,426,687 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000085176   ⟹   ENSRNOP00000069771
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl395,764,470 - 95,824,397 (+)Ensembl
Rnor_6.0 Ensembl3100,373,439 - 100,427,030 (+)Ensembl
RefSeq Acc Id: NM_001137642   ⟹   NP_001131114
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83116,219,007 - 116,279,198 (+)NCBI
mRatBN7.2395,764,388 - 95,824,582 (+)NCBI
Rnor_6.03100,366,168 - 100,426,687 (+)NCBI
Rnor_5.03106,967,785 - 107,028,416 (+)NCBI
RGSC_v3.4394,825,019 - 94,885,158 (+)RGD
Celera394,796,565 - 94,856,504 (+)RGD
Sequence:
RefSeq Acc Id: XM_017591908   ⟹   XP_017447397
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83116,219,024 - 116,279,378 (+)NCBI
mRatBN7.2395,764,405 - 95,824,756 (+)NCBI
Rnor_6.03100,373,224 - 100,426,867 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039105450   ⟹   XP_038961378
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83116,219,024 - 116,279,378 (+)NCBI
mRatBN7.2395,764,405 - 95,824,756 (+)NCBI
RefSeq Acc Id: XM_039105451   ⟹   XP_038961379
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83116,219,036 - 116,279,378 (+)NCBI
mRatBN7.2395,764,417 - 95,824,756 (+)NCBI
RefSeq Acc Id: XM_039105452   ⟹   XP_038961380
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83116,219,077 - 116,279,378 (+)NCBI
mRatBN7.2395,764,452 - 95,824,756 (+)NCBI
RefSeq Acc Id: XM_063284155   ⟹   XP_063140225
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83116,219,024 - 116,271,777 (+)NCBI
RefSeq Acc Id: NP_001131114   ⟸   NM_001137642
- UniProtKB: D3ZIA5 (UniProtKB/TrEMBL),   A6HNZ9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017447397   ⟸   XM_017591908
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000006689   ⟸   ENSRNOT00000006689
RefSeq Acc Id: ENSRNOP00000069771   ⟸   ENSRNOT00000085176
RefSeq Acc Id: XP_038961378   ⟸   XM_039105450
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JW74 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038961379   ⟸   XM_039105451
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JW74 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038961380   ⟸   XM_039105452
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JW74 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140225   ⟸   XM_063284155
- Peptide Label: isoform X3
Protein Domains
Kinesin motor

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZIA5-F1-model_v2 AlphaFold D3ZIA5 1-811 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692277
Promoter ID:EPDNEW_R2802
Type:initiation region
Name:Kif18a_1
Description:kinesin family member 18A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03100,366,220 - 100,366,280EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561740 AgrOrtholog
BioCyc Gene G2FUF-48483 BioCyc
Ensembl Genes ENSRNOG00000005037 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006689 ENTREZGENE
  ENSRNOT00000006689.7 UniProtKB/TrEMBL
  ENSRNOT00000085176.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.850.10 UniProtKB/TrEMBL
InterPro Kinesin-like_fam UniProtKB/TrEMBL
  Kinesin_motor_CS UniProtKB/TrEMBL
  Kinesin_motor_dom UniProtKB/TrEMBL
  Kinesin_motor_dom_sf UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report rno:362186 UniProtKB/TrEMBL
NCBI Gene 362186 ENTREZGENE
PANTHER CENTROMERE PROTEIN E UniProtKB/TrEMBL
  KINESIN-LIKE PROTEIN UniProtKB/TrEMBL
Pfam Kinesin UniProtKB/TrEMBL
PhenoGen Kif18a PhenoGen
PRINTS KINESINHEAVY UniProtKB/TrEMBL
PROSITE KINESIN_MOTOR_DOMAIN1 UniProtKB/TrEMBL
  KINESIN_MOTOR_DOMAIN2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000005037 RatGTEx
SMART KISc UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0G2JW74 ENTREZGENE, UniProtKB/TrEMBL
  A6HNZ9 ENTREZGENE, UniProtKB/TrEMBL
  D3ZIA5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-29 Kif18a  kinesin family member 18A  RGD1561740_predicted  similar to Kinesin family member 18A (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1561740_predicted  similar to Kinesin family member 18A (predicted)  LOC362186  similar to Kinesin family member 18A  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC362186  similar to Kinesin family member 18A      Symbol and Name status set to provisional 70820 PROVISIONAL