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Gene: Fbn1 (fibrillin 1) Rattus norvegicus
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Symbol: Fbn1
Name: fibrillin 1
Description: Predicted to have several functions, including heparin binding activity; identical protein binding activity; and signaling receptor binding activity. Involved in cellular response to insulin-like growth factor stimulus; cellular response to transforming growth factor beta stimulus; and metanephros development. Localizes to collagen-containing extracellular matrix. Biomarker of glomerulonephritis; hypertension; liver cirrhosis; mesangial proliferative glomerulonephritis; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including CREST syndrome; Weill-Marchesani syndrome; aortic disease (multiple); autosomal dominant isolated ectopia lentis 1; and bone disease (multiple). Orthologous to human FBN1 (fibrillin 1); INTERACTS WITH 1-naphthyl isothiocyanate; 3,3',4,4',5-pentachlorobiphenyl; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: fibrillin-1
Orthologs:
Homo sapiens (human) : FBN1 (fibrillin 1)  HGNC  Alliance
Mus musculus (house mouse) : Fbn1 (fibrillin 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbn1 (fibrillin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FBN1 (fibrillin 1)
Canis lupus familiaris (dog) : FBN1 (fibrillin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbn1 (fibrillin 1)
Sus scrofa (pig) : FBN1 (fibrillin 1)
Chlorocebus sabaeus (African green monkey) : FBN1 (fibrillin 1)
Heterocephalus glaber (naked mole-rat) : Fbn1 (fibrillin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03117,569,708 - 117,766,160 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3117,569,697 - 117,766,120 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03124,094,458 - 124,290,346 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43112,608,480 - 112,804,118 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13112,514,052 - 112,709,691 (-)NCBI
Celera3111,411,207 - 111,605,886 (-)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model