Bdnf (brain-derived neurotrophic factor) - Rat Genome Database

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Gene: Bdnf (brain-derived neurotrophic factor) Rattus norvegicus
Symbol: Bdnf
Name: brain-derived neurotrophic factor
RGD ID: 2202
Description: Enables neurotrophin TRKB receptor binding activity. Involved in several processes, including behavioral response to cocaine; cellular response to norepinephrine stimulus; and regulation of neuronal synaptic plasticity. Acts upstream of or within positive regulation of DNA-binding transcription factor activity; positive regulation of glucocorticoid receptor signaling pathway; and positive regulation of peptidyl-serine phosphorylation. Located in several cellular components, including mitochondrial crista; perikaryon; and synaptic vesicle. Used to study Alzheimer's disease; cystitis; eye disease (multiple); neuropathy (multiple); and status epilepticus. Biomarker of several diseases, including alcohol use disorder; attention deficit hyperactivity disorder; hypertensive encephalopathy; middle cerebral artery infarction; and sciatic neuropathy. Human ortholog(s) of this gene implicated in several diseases, including cognitive disorder (multiple); congenital central hypoventilation syndrome; neurodegenerative disease (multiple); obstructive sleep apnea; and status epilepticus. Orthologous to human BDNF (brain derived neurotrophic factor); PARTICIPATES IN brain-derived neurotrophic factor signaling pathway; Huntington's disease pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH (+)-catechin; (+)-pilocarpine; (-)-epigallocatechin 3-gallate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Brain derived neurothrophic factor; brain derived neurotrophic factor; MGC105254
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Bdnfem1Sage  
Genetic Models: SD-Bdnfem1Sage+/-
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.2396,165,042 - 96,215,621 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl396,165,042 - 96,215,615 (+)Ensembl
Rnor_6.03100,768,637 - 100,819,216 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3100,768,637 - 100,819,210 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03107,371,329 - 107,421,908 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera395,191,318 - 95,241,949 (+)NCBICelera
Cytogenetic Map3q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations     Click to see Annotation Detail View
acoustic neuroma  (ISO)
alcohol use disorder  (IEP)
alopecia  (ISO)
Alzheimer's disease  (IEP,IMP,ISO)
amnestic disorder  (ISO)
amphetamine abuse  (ISO)
Amyloid Plaques  (ISO)
anxiety disorder  (IEP)
asthma  (ISO)
Ataxia  (ISO)
atopic dermatitis  (ISO)
attention deficit hyperactivity disorder  (IEP)
autism spectrum disorder  (ISO)
autistic disorder  (ISO)
bacterial meningitis  (IEP,ISO)
bipolar disorder  (ISO)
Body Weight  (ISO)
Brain Injuries  (IEP,ISO)
brain ischemia  (ISO)
Cerebral Hemorrhage  (ISO)
Chronic Pain  (IEP)
Cocaine-Related Disorders  (IMP,ISO)
cognitive disorder  (ISO)
colitis  (ISO)
color blindness  (ISO)
congenital central hypoventilation syndrome  (ISO)
cystitis  (IEP,IMP)
Deafness  (ISO)
Diabetic Nephropathies  (IMP)
diabetic neuropathy  (IMP)
diabetic retinopathy  (IEP)
Drug Eruptions  (ISO)
epilepsy  (ISO)
epilepsy with generalized tonic-clonic seizures  (ISO)
Experimental Autoimmune Encephalomyelitis  (IEP)
Experimental Diabetes Mellitus  (IEP)
focal epilepsy  (ISO)
Frontotemporal Lobar Degeneration  (ISO)
genetic disease  (ISO)
glaucoma  (IDA,IEP,ISO)
Gliosis  (ISO)
Hearing Loss  (IEP)
Hearing Loss, Noise-Induced  (IEP,ISO)
heroin dependence  (ISO)
Huntington's disease  (ISO)
Hyperalgesia  (IDA,IEP,IMP,ISO)
Hyperoxia  (IEP)
hypertensive encephalopathy  (IEP)
hypothyroidism  (IEP)
Hypoxia  (ISO)
Inflammation  (IEP,ISO)
inner ear disease  (ISO)
intellectual disability  (ISO)
intermediate coronary syndrome  (ISO)
interstitial lung disease  (ISO)
Intervertebral Disc Displacement  (IEP)
irritable bowel syndrome  (ISO)
keratoconus  (ISO)
Leukoencephalopathies  (IEP)
low tension glaucoma  (ISO)
major depressive disorder  (ISO)
Memory Disorders  (ISO)
mental depression  (IEP,ISO)
Metabolic Syndrome  (ISO)
middle cerebral artery infarction  (IEP)
morbid obesity  (ISO)
multiple sclerosis  (ISO)
Nasal Polyps  (ISO)
neovascular inflammatory vitreoretinopathy  (ISO)
Nerve Degeneration  (IEP,ISO)
Nerve Injuries  (IEP)
nervous system disease  (ISO)
nicotine dependence  (ISO)
obesity  (ISO)
obsessive-compulsive disorder  (ISO)
obstructive sleep apnea  (ISO)
Optic Nerve Injuries  (IEP,ISO)
Pain  (IEP)
Pain, Referred  (IMP)
Parkinson's disease  (ISO)
Parkinsonism  (ISO)
Peripheral Nerve Injuries  (IEP,ISO)
post-traumatic stress disorder  (ISO)
Presbycusis  (IEP)
primary open angle glaucoma  (ISO)
psychotic disorder  (ISO)
pulmonary fibrosis  (ISO)
pulmonary sarcoidosis  (ISO)
Radiation Injuries  (IEP)
Reperfusion Injury  (IEP)
Respiration Disorders  (ISO)
Respiratory Tract Infections  (ISO)
Retina Reperfusion Injury  (ISO)
retinal degeneration  (IDA,ISO)
rhinitis  (IEP,ISO)
schizophrenia  (ISO)
sciatic neuropathy  (IDA,IEP)
Seasonal Allergic Rhinitis  (ISO)
sensorineural hearing loss  (ISO)
Sjogren's syndrome  (ISO)
Sleep Deprivation  (IEP)
Spinal Cord Injuries  (IDA,IEP,ISO)
Spinal Cord Reperfusion Injury  (IEP)
status epilepticus  (IMP,ISO)
Stomach Neoplasms  (ISO)
systemic scleroderma  (ISO)
Tinnitus  (IEP,ISO)
Tobacco Use Disorder  (ISO)
type 2 diabetes mellitus  (ISO)
urticaria  (ISO)
vascular dementia  (IEP)
Visceral Pain  (ISO)
visual epilepsy  (ISO)
withdrawal disorder  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (EXP)
(+)-epicatechin-3-O-gallate  (ISO)
(+)-pilocarpine  (EXP,ISO)
(+)-syringaresinol beta-D-glucoside  (ISO)
(-)-epigallocatechin 3-gallate  (EXP,ISO)
(20S)-ginsenoside Rg3  (ISO)
(R)-Salsolinol  (EXP)
(R,R,R)-alpha-tocopherol  (ISO)
(S)-3,5-dihydroxyphenylglycine  (ISO)
(S)-amphetamine  (EXP,ISO)
(S)-colchicine  (EXP)
(S)-nicotine  (EXP,ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (EXP)
1-bromopropane  (EXP,ISO)
1-chloro-2,4-dinitrobenzene  (EXP)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
13,14-dihydro-Delta(12)-prostaglandin J2  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2,5-hexanedione  (EXP)
2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid  (ISO)
2-methyl-6-(phenylethynyl)pyridine  (EXP)
3',5'-cyclic AMP  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-dihydroxybenzoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (EXP,ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-nitropropanoic acid  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-[1-hydroxy-2-[4-(phenylmethyl)-1-piperidinyl]propyl]phenol  (EXP)
4-hydroxynon-2-enal  (EXP)
5-aza-2'-deoxycytidine  (EXP,ISO)
5-azacytidine  (ISO)
5-fluorouracil  (EXP)
5-methoxypsoralen  (ISO)
6-anilino-5,8-quinolinedione  (ISO)
6-Cyano-7-nitroquinoxaline-2,3-dione  (EXP)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (ISO)
[6]-Shogaol  (ISO)
acrolein  (EXP)
acrylamide  (EXP)
actinomycin D  (EXP)
aflatoxin B1  (EXP,ISO)
agathisflavone  (EXP)
agmatine  (ISO)
agomelatine  (EXP,ISO)
alcohol  (ISO)
aldehydo-D-glucosamine  (ISO)
all-trans-retinoic acid  (ISO)
alpha-D-galactose  (ISO)
AM-251  (ISO)
amantadine  (EXP)
amiodarone  (EXP)
ammonium chloride  (EXP)
amphetamine  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
apigenin  (EXP)
arachidonic acid  (ISO)
aristolochic acid  (ISO)
Aroclor 1254  (ISO)
arsane  (EXP,ISO)
arsanilic acid  (EXP)
arsenic atom  (EXP,ISO)
arsenite(3-)  (ISO)
arsenous acid  (EXP,ISO)
Asiaticoside  (EXP)
atrazine  (EXP,ISO)
Bardoxolone methyl  (ISO)
Bay-K-8644  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-D-glucosamine  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
bromocriptine  (ISO)
bucladesine  (ISO)
buprenorphine  (EXP)
Butylparaben  (EXP)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (EXP)
calcitriol  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
cannabidiol  (EXP,ISO)
capsaicin  (EXP)
carbamazepine  (EXP)
carbon dioxide  (EXP)
carbon monoxide  (EXP)
carbon nanotube  (ISO)
chaetocin  (EXP)
chlorohydrocarbon  (ISO)
chloroprene  (ISO)
chlorpromazine  (EXP,ISO)
chlorpyrifos  (EXP,ISO)
cholesterol  (EXP)
choline  (ISO)
chondroitin sulfate  (ISO)
chrysin  (ISO)
cisplatin  (EXP,ISO)
Citreoviridin  (ISO)
clofibrate  (ISO)
clopidogrel  (ISO)
clozapine  (EXP)
cocaine  (EXP,ISO)
colforsin daropate hydrochloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
corticosterone  (EXP,ISO)
creatine  (ISO)
crocidolite asbestos  (ISO)
crocin-1  (EXP)
Cuprizon  (EXP)
curcumin  (EXP,ISO)
cyclophosphamide  (EXP)
cyclosporin A  (EXP,ISO)
cyfluthrin  (EXP)
cypermethrin  (EXP,ISO)
daidzein 7-O-beta-D-glucoside  (ISO)
dantrolene  (ISO)
decabromodiphenyl ether  (EXP,ISO)
deguelin  (ISO)
dermatan sulfate  (ISO)
desipramine  (ISO)
dexamethasone  (EXP,ISO)
diallyl disulfide  (ISO)
diarsenic trioxide  (EXP,ISO)
diazepam  (EXP,ISO)
diazinon  (ISO)
dibutyl phthalate  (EXP,ISO)
dichloroacetic acid  (ISO)
diethylstilbestrol  (EXP,ISO)
dihydroactinidiolide  (ISO)
diisopropyl fluorophosphate  (EXP)
dioxygen  (EXP,ISO)
disulfiram  (ISO)
dizocilpine maleate  (EXP)
donepezil hydrochloride  (ISO)
dopamine  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
echinacoside  (EXP)
elemental selenium  (EXP)
endosulfan  (EXP)
enzacamene  (EXP)
epoxiconazole  (EXP)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
etoposide  (ISO)
eugenol  (ISO)
excitatory amino acid agonist  (EXP)
fenvalerate  (EXP)
fingolimod hydrochloride  (ISO)
fisetin  (EXP)
fluoranthene  (ISO)
fluoxetine  (EXP,ISO)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
Fusaric acid  (EXP)
galactose  (ISO)
gallic acid  (ISO)
gallocatechin  (ISO)
gamma-aminobutyric acid  (EXP)
gamma-hexachlorocyclohexane  (EXP)
gemcitabine  (ISO)
genistein  (ISO)
gentamycin  (EXP)
geraniol  (ISO)
glycidol  (EXP)
glycyrrhizinic acid  (EXP)
glyphosate  (ISO)
haloperidol  (EXP,ISO)
herbicide  (EXP)
heroin  (EXP,ISO)
hydrogen peroxide  (ISO)
ifosfamide  (EXP)
imipramine  (EXP,ISO)
kainic acid  (EXP)
ketamine  (EXP,ISO)
ketanserin  (EXP)
KT 5823  (EXP,ISO)
L-ascorbic acid  (ISO)
L-methionine  (ISO)
lamotrigine  (EXP)
lead diacetate  (EXP,ISO)
lead(0)  (EXP)
lead(2+)  (EXP)
linuron  (EXP)
lipopolysaccharide  (EXP)
lithium atom  (EXP,ISO)
lithium chloride  (ISO)
lithium hydride  (EXP,ISO)
lovastatin  (EXP)
LY294002  (ISO)
lycopene  (EXP,ISO)
maneb  (EXP,ISO)
manganese atom  (EXP,ISO)
manganese(0)  (EXP,ISO)
manganese(II) chloride  (EXP,ISO)
melatonin  (EXP,ISO)
mercury atom  (ISO)
mercury dibromide  (ISO)
mercury dichloride  (ISO)
mercury(0)  (ISO)
metformin  (EXP)
methamphetamine  (EXP,ISO)
methyl beta-cyclodextrin  (ISO)
methyl methanesulfonate  (ISO)
methylglyoxal  (ISO)
methyllycaconitine  (ISO)
methylmercury chloride  (EXP,ISO)
methylphenidate  (EXP,ISO)
mevastatin  (ISO)
mifepristone  (EXP,ISO)
morin  (EXP)
morphine  (EXP,ISO)
muscimol  (EXP)
N-acetyl-L-cysteine  (ISO)
N-ethyl-N-nitrosourea  (EXP)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP)
N-methyl-N-nitrosourea  (EXP)
naproxen  (EXP)
nicardipine  (EXP)
nickel atom  (ISO)
nicotine  (EXP,ISO)
nicotinic acid  (EXP)
nifedipine  (EXP)
nimodipine  (ISO)
nitric oxide  (ISO)
ochratoxin A  (EXP)
olanzapine  (EXP,ISO)
ouabain  (EXP)
Oxadiazon  (ISO)
oxaliplatin  (EXP)
oxidopamine  (ISO)
ozone  (EXP,ISO)
paclitaxel  (EXP)
paliperidone palmitate  (EXP)
panaxydol  (EXP)
papaverine  (EXP)
paracetamol  (EXP,ISO)
paraldehyde  (EXP)
paraquat  (EXP,ISO)
parathion-methyl  (EXP)
paroxetine  (ISO)
pentetrazol  (EXP,ISO)
pentobarbital  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
permethrin  (EXP,ISO)
peroxynitrous acid  (EXP)
phenobarbital  (ISO)
phenylephrine  (EXP)
picrotoxin  (EXP,ISO)
pioglitazone  (ISO)
poly(I:C)  (EXP,ISO)
potassium atom  (EXP,ISO)
potassium chloride  (ISO)
potassium chromate  (ISO)
prasugrel hydrochloride  (EXP)
prochloraz  (EXP)
procymidone  (EXP)
progesterone  (EXP,ISO)
propanal  (ISO)
pyrethrins  (ISO)
Pyridostigmine bromide  (ISO)
pyrrolidine dithiocarbamate  (ISO)
quercetin  (ISO)
quetiapine fumarate  (EXP)
quinolinic acid  (EXP)
reserpine  (EXP,ISO)
resveratrol  (EXP,ISO)
rimonabant  (ISO)
risperidone  (EXP,ISO)
ritanserin  (EXP)
rivastigmine  (EXP)
rolipram  (EXP)
romidepsin  (EXP)
rotenone  (EXP,ISO)
salvianolic acid B  (ISO)
saxagliptin  (EXP)
SB 431542  (ISO)
scopolamine  (EXP,ISO)
selenium atom  (EXP)
serotonin  (EXP,ISO)
sertraline  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (EXP)
sirolimus  (ISO)
SKF-96365 hydrochloride  (ISO)
SL-327  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (EXP,ISO)
Soman  (EXP)
sterigmatocystin  (EXP)
streptozocin  (EXP,ISO)
sulforaphane  (ISO)
sumatriptan  (EXP)
tacrine  (ISO)
tacrolimus hydrate  (EXP)
tadalafil  (ISO)
tamibarotene  (EXP,ISO)
tamoxifen  (ISO)
taurine  (EXP,ISO)
telmisartan  (ISO)
tert-butyl hydroperoxide  (ISO)
Testosterone propionate  (EXP)
tetrodotoxin  (EXP,ISO)
thioacetamide  (ISO)
titanium dioxide  (ISO)
toluene  (ISO)
topiramate  (EXP)
torcetrapib  (ISO)
tranylcypromine  (EXP)
triacsin C  (ISO)
triazolam  (ISO)
triazophos  (EXP)
trichloroethene  (ISO)
trichostatin A  (EXP,ISO)
undecane  (EXP)
valproic acid  (EXP,ISO)
venlafaxine hydrochloride  (EXP)
veratridine  (EXP,ISO)
vinclozolin  (EXP)
VX nerve agent  (ISO)
wortmannin  (EXP,ISO)
xenon atom  (EXP)
xenon(0)  (EXP)
zearalenone  (ISO)
zinc atom  (ISO)
zinc dichloride  (EXP)
zinc sulfate  (ISO)
zinc(0)  (ISO)
zolpidem  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aging  (IEP)
axon extension  (ISO)
axon guidance  (ISO)
axon target recognition  (ISO)
behavioral fear response  (ISO)
behavioral response to cocaine  (IMP)
cellular response to nerve growth factor stimulus  (IEP)
cellular response to norepinephrine stimulus  (IEP)
cellular response to tumor necrosis factor  (IEP)
chronic inflammatory response  (IEP)
circadian rhythm  (ISO)
cognition  (IEP)
collateral sprouting  (IEA,ISO)
conditioned place preference  (IMP)
dendrite development  (ISO)
dendrite extension  (ISO)
excitatory postsynaptic potential  (IMP)
fear response  (ISO)
feeding behavior  (ISO)
gamma-aminobutyric acid signaling pathway  (ISO)
glutamate secretion  (ISO)
inhibitory postsynaptic potential  (ISO)
inner ear development  (ISO)
learning  (IMP)
learning or memory  (ISO)
mechanoreceptor differentiation  (ISO)
memory  (IBA)
mitochondrial electron transport, NADH to ubiquinone  (IMP)
modulation of chemical synaptic transmission  (IBA)
negative regulation of apoptotic process  (ISO)
negative regulation of apoptotic signaling pathway  (ISO)
negative regulation of cell death  (ISO)
negative regulation of myotube differentiation  (IMP)
negative regulation of neuroblast proliferation  (ISO)
negative regulation of neuron apoptotic process  (IBA,ISO)
negative regulation of neuron death  (IMP)
negative regulation of striated muscle tissue development  (IMP)
negative regulation of synaptic transmission, GABAergic  (ISO)
nerve development  (IBA,ISO)
nerve growth factor signaling pathway  (IBA)
nervous system development  (IDA)
neuron apoptotic process  (ISO)
neuron differentiation  (TAS)
neuron projection extension  (IDA)
neuron projection morphogenesis  (IBA)
neuron recognition  (ISO)
peptidyl-serine phosphorylation  (ISO)
peripheral nervous system development  (IBA)
positive regulation of axon extension  (ISO)
positive regulation of collateral sprouting  (IBA,IEA,ISO)
positive regulation of DNA-binding transcription factor activity  (IDA)
positive regulation of glucocorticoid receptor signaling pathway  (IDA)
positive regulation of long-term neuronal synaptic plasticity  (IMP)
positive regulation of neuron differentiation  (ISO)
positive regulation of neuron projection development  (ISO)
positive regulation of peptidyl-serine phosphorylation  (IBA,IGI,ISO)
positive regulation of receptor binding  (IDA,IEA,ISO)
positive regulation of synapse assembly  (IEA,ISO)
regeneration  (IDA)
regulation of axon extension  (IMP)
regulation of collateral sprouting  (ISO)
regulation of long-term neuronal synaptic plasticity  (IDA)
regulation of metabolic process  (ISO)
regulation of neuron apoptotic process  (ISO)
regulation of neuron differentiation  (IBA)
regulation of retinal cell programmed cell death  (ISO)
regulation of short-term neuronal synaptic plasticity  (IDA)
regulation of synaptic plasticity  (ISO)
response to activity  (IEP)
response to anesthetic  (IEP)
response to auditory stimulus  (IEP)
response to electrical stimulus  (IEP)
response to food  (IEP)
response to hormone  (IEP)
response to hyperoxia  (IEP)
response to hypoxia  (IEP)
response to L-glutamate  (IEP)
response to light intensity  (IEP)
response to light stimulus  (IEP)
response to nerve growth factor  (IEP)
response to nutrient levels  (IEP)
response to potassium ion  (IEP)
response to tumor necrosis factor  (IEP)
response to vitamin A  (IEP)
response to xenobiotic stimulus  (IEP,ISO)
retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission  (ISO)
signal transduction  (IEA)
synapse assembly  (IEA,ISO)
taste bud development  (ISO)
transmembrane receptor protein tyrosine kinase signaling pathway  (IBA)
ureteric bud development  (ISO)

Cellular Component

Molecular Function


References - curated
1. Aid T, etal., J Neurosci Res. 2007 Feb 15;85(3):525-35.
2. Al-Ayadhi LY, Neurochem Res. 2012 Feb;37(2):394-400. doi: 10.1007/s11064-011-0624-x. Epub 2011 Oct 9.
3. Alonso M, etal., Hippocampus 2002;12(4):551-60.
4. Andiappan AK, etal., Cytokine. 2011 Nov;56(2):218-23. doi: 10.1016/j.cyto.2011.05.008. Epub 2011 Jun 30.
5. Asai N, etal., Exp Eye Res. 2007 Sep;85(3):346-55. Epub 2007 Jun 15.
6. Avwenagha O, etal., Neuroscience. 2006 Jul 7;140(3):913-28. Epub 2006 Apr 19.
7. Baker-Herman TL, etal., Nat Neurosci. 2004 Jan;7(1):48-55. Epub 2003 Dec 14.
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PMID:18052976   PMID:18191115   PMID:18194437   PMID:18219447   PMID:18242714   PMID:18262500   PMID:18289509   PMID:18301726   PMID:18304740   PMID:18309046   PMID:18338800   PMID:18339694  
PMID:18353280   PMID:18373519   PMID:18381242   PMID:18395922   PMID:18398848   PMID:18420184   PMID:18432062   PMID:18445109   PMID:18445478   PMID:18450779   PMID:18474605   PMID:18496748  
PMID:18515408   PMID:18538870   PMID:18539944   PMID:18544182   PMID:18547240   PMID:18563704   PMID:18571429   PMID:18573344   PMID:18585459   PMID:18586239   PMID:18596175   PMID:18604298  
PMID:18625328   PMID:18635195   PMID:18636983   PMID:18637202   PMID:18655199   PMID:18680554   PMID:18685070   PMID:18728191   PMID:18766297   PMID:18813339   PMID:18852301   PMID:18923034  
PMID:18937073   PMID:18957307   PMID:18973595   PMID:18992724   PMID:19036963   PMID:19046371   PMID:19059263   PMID:19072257   PMID:19083991   PMID:19094092   PMID:19124536   PMID:19126684  
PMID:19147841   PMID:19150054   PMID:19150437   PMID:19164786   PMID:19175406   PMID:19179431   PMID:19181453   PMID:19181454   PMID:19183490   PMID:19188859   PMID:19190544   PMID:19217433  
PMID:19222557   PMID:19267952   PMID:19295157   PMID:19295451   PMID:19321768   PMID:19332029   PMID:19339597   PMID:19344636   PMID:19368814   PMID:19387610   PMID:19418263   PMID:19418634  
PMID:19424097   PMID:19437410   PMID:19448629   PMID:19524026   PMID:19524560   PMID:19530223   PMID:19546592   PMID:19547753   PMID:19555673   PMID:19555760   PMID:19558709   PMID:19570026  
PMID:19662538   PMID:19665523   PMID:19702335   PMID:19726361   PMID:19726638   PMID:19755135   PMID:19796445   PMID:19805324   PMID:19818836   PMID:19822210   PMID:19837135   PMID:19864562  
PMID:19880806   PMID:19893098   PMID:19906967   PMID:19923273   PMID:19925812   PMID:19937808   PMID:19959385   PMID:19965374   PMID:20029969   PMID:20029971   PMID:20034565   PMID:20047714  
PMID:20083190   PMID:20087891   PMID:20138132   PMID:20164202   PMID:20170723   PMID:20172535   PMID:20176405   PMID:20186743   PMID:20206238   PMID:20219632   PMID:20220070   PMID:20222154  
PMID:20226152   PMID:20232397   PMID:20335141   PMID:20392195   PMID:20398635   PMID:20405200   PMID:20407211   PMID:20410295   PMID:20427644   PMID:20452683   PMID:20522777   PMID:20535563  
PMID:20580927   PMID:20601027   PMID:20603120   PMID:20614233   PMID:20615547   PMID:20625416   PMID:20635439   PMID:20639200   PMID:20643185   PMID:20644345   PMID:20648648   PMID:20649532  
PMID:20649843   PMID:20708057   PMID:20708081   PMID:20711185   PMID:20722975   PMID:20728493   PMID:20731656   PMID:20814019   PMID:20838921   PMID:20848610   PMID:20854252   PMID:20890994  
PMID:20946939   PMID:21034794   PMID:21044076   PMID:21074587   PMID:21082236   PMID:21098478   PMID:21134422   PMID:21172615   PMID:21198979   PMID:21210848   PMID:21225335   PMID:21248226  
PMID:21254300   PMID:21255015   PMID:21269288   PMID:21306736   PMID:21307245   PMID:21307800   PMID:21334417   PMID:21335064   PMID:21338685   PMID:21349227   PMID:21357693   PMID:21420441  
PMID:21430148   PMID:21436126   PMID:21474450   PMID:21515660   PMID:21525862   PMID:21527636   PMID:21530554   PMID:21540781   PMID:21562951   PMID:21656118   PMID:21690335   PMID:21723373  
PMID:21730062   PMID:21756773   PMID:21756980   PMID:21767606   PMID:21792677   PMID:21801814   PMID:21803120   PMID:21835234   PMID:21839142   PMID:21839807   PMID:21856381   PMID:21861389  
PMID:21865474   PMID:21890320   PMID:21907460   PMID:21945647   PMID:21946312   PMID:22024546   PMID:22027236   PMID:22044922   PMID:22050733   PMID:22069327   PMID:22128191   PMID:22134693  
PMID:22174809   PMID:22178325   PMID:22178659   PMID:22193444   PMID:22195050   PMID:22209827   PMID:22223265   PMID:22227452   PMID:22234237   PMID:22244747   PMID:22253429   PMID:22265241  
PMID:22272355   PMID:22280975   PMID:22306205   PMID:22345308   PMID:22374757   PMID:22410736   PMID:22426107   PMID:22428625   PMID:22442695   PMID:22469747   PMID:22499464   PMID:22500633  
PMID:22510533   PMID:22515203   PMID:22521816   PMID:22527999   PMID:22553040   PMID:22561407   PMID:22573254   PMID:22573708   PMID:22649026   PMID:22650038   PMID:22650039   PMID:22650040  
PMID:22650041   PMID:22650043   PMID:22672085   PMID:22678720   PMID:22730318   PMID:22778217   PMID:22796076   PMID:22841916   PMID:22847550   PMID:22848609   PMID:22886995   PMID:22917619  
PMID:22930524   PMID:22936723   PMID:22959240   PMID:23017014   PMID:23035088   PMID:23056528   PMID:23058367   PMID:23080167   PMID:23086941   PMID:23134146   PMID:23157205   PMID:23160045  
PMID:23168995   PMID:23179587   PMID:23185000   PMID:23189980   PMID:23219910   PMID:23237316   PMID:23255148   PMID:23261589   PMID:23271640   PMID:23274899   PMID:23326507   PMID:23337714  
PMID:23337936   PMID:23349925   PMID:23367482   PMID:23376487   PMID:23392678   PMID:23432085   PMID:23436435   PMID:23439217   PMID:23512738   PMID:23531843   PMID:23534605   PMID:23550026  
PMID:23564488   PMID:23588198   PMID:23599427   PMID:23643896   PMID:23700463   PMID:23704876   PMID:23715956   PMID:23749289   PMID:23762244   PMID:23770418   PMID:23785138   PMID:23811393  
PMID:23825410   PMID:23842743   PMID:23870838   PMID:23918351   PMID:23942837   PMID:23949197   PMID:23963709   PMID:23993653   PMID:23999152   PMID:24006456   PMID:24021607   PMID:24035762  
PMID:24076087   PMID:24092446   PMID:24103311   PMID:24114393   PMID:24127005   PMID:24157309   PMID:24201284   PMID:24244357   PMID:24280707   PMID:24302729   PMID:24303055   PMID:24316448  
PMID:24321407   PMID:24345682   PMID:24361450   PMID:24365909   PMID:24372023   PMID:24378336   PMID:24401942   PMID:24431454   PMID:24440750   PMID:24465591   PMID:24503120   PMID:24573299  
PMID:24625911   PMID:24709620   PMID:24714156   PMID:24747049   PMID:24747659   PMID:24753016   PMID:24802968   PMID:24811179   PMID:24839168   PMID:24917666   PMID:24921856   PMID:24934279  
PMID:24965890   PMID:24966334   PMID:24968020   PMID:24978397   PMID:24978930   PMID:24993297   PMID:25010399   PMID:25011012   PMID:25052557   PMID:25055143   PMID:25059794   PMID:25082546  
PMID:25087780   PMID:25110093   PMID:25143381   PMID:25182413   PMID:25203492   PMID:25209292   PMID:25226925   PMID:25231482   PMID:25241777   PMID:25282819   PMID:25392083   PMID:25424467  
PMID:25444867   PMID:25445195   PMID:25449846   PMID:25451258   PMID:25453757   PMID:25481360   PMID:25519736   PMID:25527489   PMID:25542970   PMID:25555929   PMID:25559382   PMID:25568287  
PMID:25623071   PMID:25665281   PMID:25681548   PMID:25692578   PMID:25755749   PMID:25783782   PMID:25860428   PMID:25868795   PMID:25869354   PMID:25886766   PMID:25894678   PMID:25904806  
PMID:25934485   PMID:25963324   PMID:26000806   PMID:26019338   PMID:26027495   PMID:26047381   PMID:26088421   PMID:26090759   PMID:26111610   PMID:26111928   PMID:26146031   PMID:26148339  
PMID:26163515   PMID:26166726   PMID:26189832   PMID:26198255   PMID:26200505   PMID:26211445   PMID:26239042   PMID:26239616   PMID:26291061   PMID:26339375   PMID:26368940   PMID:26388293  
PMID:26391661   PMID:26396035   PMID:26398857   PMID:26449489   PMID:26459016   PMID:26469350   PMID:26471218   PMID:26554621   PMID:26571801   PMID:26586578   PMID:26630405   PMID:26659122  
PMID:26676568   PMID:26682524   PMID:26691781   PMID:26700412   PMID:26708520   PMID:26712630   PMID:26794594   PMID:26802511   PMID:26820887   PMID:26844865   PMID:26861177   PMID:26877199  
PMID:26881097   PMID:26888068   PMID:26926964   PMID:26941165   PMID:26960058   PMID:27006395   PMID:27010597   PMID:27013094   PMID:27028464   PMID:27085775   PMID:27094192   PMID:27132084  
PMID:27137405   PMID:27151332   PMID:27154426   PMID:27181637   PMID:27252349   PMID:27267245   PMID:27270670   PMID:27306412   PMID:27310873   PMID:27329329   PMID:27381812   PMID:27435421  
PMID:27474832   PMID:27503312   PMID:27521083   PMID:27550421   PMID:27569259   PMID:27597545   PMID:27611779   PMID:27624937   PMID:27639585   PMID:27683907   PMID:27693383   PMID:27727393  
PMID:27744091   PMID:27771283   PMID:27830679   PMID:27832087   PMID:27857218   PMID:27874237   PMID:27913431   PMID:27914953   PMID:27926876   PMID:28072837   PMID:28078614   PMID:28119091  
PMID:28145853   PMID:28238708   PMID:28254195   PMID:28258626   PMID:28261618   PMID:28281382   PMID:28306606   PMID:28330827   PMID:28420943   PMID:28440877   PMID:28445707   PMID:28492549  
PMID:28524001   PMID:28576309   PMID:28598964   PMID:28600519   PMID:28622174   PMID:28634074   PMID:28640008   PMID:28663119   PMID:28698933   PMID:28711394   PMID:28767193   PMID:28770018  
PMID:28821448   PMID:28829495   PMID:28854337   PMID:28855298   PMID:28857460   PMID:28865749   PMID:28890399   PMID:28965325   PMID:29075579   PMID:29098710   PMID:29126980   PMID:29263199  
PMID:29288061   PMID:29305263   PMID:29353374   PMID:29380665   PMID:29401579   PMID:29420916   PMID:29425916   PMID:29499310   PMID:29540150   PMID:29545098   PMID:29611441   PMID:29621970  
PMID:29648487   PMID:29704115   PMID:29773102   PMID:29777700   PMID:29781158   PMID:29800645   PMID:29802680   PMID:29911174   PMID:30001178   PMID:30024334   PMID:30076998   PMID:30100066  
PMID:30102916   PMID:30119135   PMID:30127343   PMID:30129982   PMID:30132570   PMID:30151608   PMID:30185459   PMID:30200858   PMID:30226568   PMID:30308090   PMID:30308117   PMID:30373907  
PMID:30477252   PMID:30483749   PMID:30503681   PMID:30548775   PMID:30550948   PMID:30569121   PMID:30639279   PMID:30680641   PMID:30695408   PMID:30710509   PMID:30741614   PMID:30761261  
PMID:30851317   PMID:30940563   PMID:30956976   PMID:31014242   PMID:31017891   PMID:31114979   PMID:31134851   PMID:31213568   PMID:31219215   PMID:31281833   PMID:31327126   PMID:31329835  
PMID:31412259   PMID:31415765   PMID:31449911   PMID:31492038   PMID:31524100   PMID:31539886   PMID:31557760   PMID:31577916   PMID:31694441   PMID:31770584   PMID:31773433   PMID:31828524  
PMID:31883222   PMID:31883511   PMID:31915257   PMID:31922368   PMID:31960229   PMID:31973999   PMID:31982414   PMID:32027953   PMID:32043504   PMID:32120967   PMID:32179157   PMID:32189593  
PMID:32193501   PMID:32214273   PMID:32219700   PMID:32222405   PMID:32323597   PMID:32417176   PMID:32445041   PMID:32488870   PMID:32505509   PMID:32507324   PMID:32585251   PMID:32588398  
PMID:32671697   PMID:32681810   PMID:32738378   PMID:32770453   PMID:32820184   PMID:32822705   PMID:33075004   PMID:33103739   PMID:33147870   PMID:33148515   PMID:33204065   PMID:33206632  
PMID:33245480   PMID:33290797   PMID:33359781   PMID:33436052   PMID:33560226   PMID:33577886   PMID:33649977   PMID:33745752   PMID:33763156   PMID:33874962   PMID:33961393   PMID:33982757  
PMID:34008409   PMID:34061025   PMID:34068707   PMID:34086671   PMID:34101873   PMID:34102241   PMID:34192516   PMID:34225593   PMID:34274327   PMID:34295224   PMID:34299002   PMID:34328517  
PMID:34348149   PMID:34374467   PMID:34374900   PMID:34454019   PMID:34497360   PMID:34529365   PMID:34536437   PMID:34543287   PMID:34619155   PMID:34695541   PMID:34700232   PMID:34743976  
PMID:34869766   PMID:34929632   PMID:34937120   PMID:34948299   PMID:34960080   PMID:35013359   PMID:35216241   PMID:35256586   PMID:35439934  


Comparative Map Data
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.2396,165,042 - 96,215,621 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl396,165,042 - 96,215,615 (+)Ensembl
Rnor_6.03100,768,637 - 100,819,216 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3100,768,637 - 100,819,210 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03107,371,329 - 107,421,908 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera395,191,318 - 95,241,949 (+)NCBICelera
Cytogenetic Map3q34NCBI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381127,654,893 - 27,722,030 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1127,654,893 - 27,722,058 (-)EnsemblGRCh38hg38GRCh38
GRCh371127,676,440 - 27,743,577 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361127,633,016 - 27,699,872 (-)NCBINCBI36hg18NCBI36
Build 341127,633,019 - 27,637,249NCBI
Celera1127,822,548 - 27,889,725 (-)NCBI
Cytogenetic Map11p14.1NCBI
HuRef1127,374,586 - 27,441,772 (-)NCBIHuRef
CHM1_11127,675,184 - 27,742,527 (-)NCBICHM1_1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm392109,505,045 - 109,557,388 (+)NCBIGRCm39mm39
GRCm39 Ensembl2109,505,045 - 109,557,352 (+)Ensembl
GRCm382109,674,700 - 109,727,043 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2109,674,700 - 109,727,007 (+)EnsemblGRCm38mm10GRCm38
MGSCv372109,514,857 - 109,567,200 (+)NCBIGRCm37mm9NCBIm37
MGSCv362109,475,539 - 109,527,845 (+)NCBImm8
Celera2110,835,441 - 110,887,723 (+)NCBICelera
Cytogenetic Map2E3NCBI
cM Map256.63NCBI
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
ChiLan1.0 EnsemblNW_0049554766,772,088 - 6,822,588 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554766,773,244 - 6,822,201 (-)NCBIChiLan1.0ChiLan1.0
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
PanPan1.11127,520,306 - 27,589,239 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1127,520,312 - 27,589,239 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01127,618,322 - 27,687,661 (-)NCBIMhudiblu_PPA_v0panPan3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.12148,191,580 - 48,243,699 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2148,192,670 - 48,204,480 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2147,689,871 - 47,691,000 (-)NCBI
ROS_Cfam_1.02149,335,793 - 49,386,964 (-)NCBI
UMICH_Zoey_3.12148,338,131 - 48,339,260 (-)NCBI
UNSW_CanFamBas_1.02148,489,388 - 48,490,517 (-)NCBI
UU_Cfam_GSD_1.02149,083,467 - 49,084,596 (-)NCBI
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
HiC_Itri_2NW_02440494736,374,992 - 36,427,979 (+)NCBI
SpeTri2.0NW_0049365405,530,081 - 5,582,765 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
Sscrofa11.1 Ensembl232,623,268 - 32,679,164 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1232,623,668 - 32,679,293 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2235,206,996 - 35,265,002 (+)NCBISscrofa10.2Sscrofa10.2susScr3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
ChlSab1.1137,386,825 - 37,451,380 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl137,449,593 - 37,450,336 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666038134,690,869 - 134,762,531 (+)NCBIVero_WHO_p1.0
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
HetGla 1.0NW_00462476617,281,882 - 17,330,601 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2396,210,913 - 96,211,109 (+)MAPPERmRatBN7.2
Rnor_6.03100,814,509 - 100,814,704NCBIRnor6.0
Rnor_5.03107,417,201 - 107,417,396UniSTSRnor5.0
Celera395,237,242 - 95,237,437UniSTS
Cytogenetic Map3q33UniSTS
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2396,210,959 - 96,211,098 (+)MAPPERmRatBN7.2
Rnor_6.03100,814,555 - 100,814,693NCBIRnor6.0
Rnor_5.03107,417,247 - 107,417,385UniSTSRnor5.0
Celera395,237,288 - 95,237,426UniSTS
Cytogenetic Map3q33UniSTS
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2396,212,191 - 96,212,608 (+)MAPPERmRatBN7.2
Rnor_6.03100,815,787 - 100,816,203NCBIRnor6.0
Rnor_5.03107,418,479 - 107,418,895UniSTSRnor5.0
Celera395,238,520 - 95,238,936UniSTS
Cytogenetic Map3q33UniSTS
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2396,213,832 - 96,213,987 (+)MAPPERmRatBN7.2
Rnor_6.03100,817,428 - 100,817,582NCBIRnor6.0
Rnor_5.03107,420,120 - 107,420,274UniSTSRnor5.0
Celera395,240,161 - 95,240,315UniSTS
RH 3.4 Map3750.8UniSTS
Cytogenetic Map3q33UniSTS
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2396,212,223 - 96,212,305 (+)MAPPERmRatBN7.2
Rnor_6.03100,815,819 - 100,815,900NCBIRnor6.0
Rnor_5.03107,418,511 - 107,418,592UniSTSRnor5.0
Celera395,238,552 - 95,238,633UniSTS
Cytogenetic Map3q33UniSTS
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2396,211,989 - 96,212,604 (+)MAPPERmRatBN7.2
Rnor_6.03100,815,585 - 100,816,199NCBIRnor6.0
Rnor_5.03107,418,277 - 107,418,891UniSTSRnor5.0
Celera395,238,318 - 95,238,932UniSTS
Cytogenetic Map3q33UniSTS
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2396,212,236 - 96,212,458 (+)MAPPERmRatBN7.2
Rnor_6.03100,815,832 - 100,816,053NCBIRnor6.0
Rnor_5.03107,418,524 - 107,418,745UniSTSRnor5.0
Celera395,238,565 - 95,238,786UniSTS
Cytogenetic Map3q33UniSTS

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)395735366140735366Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)389772419134772419Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)364655305115665732Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582219Bw63Body weight QTL 633.80.001body mass (VT:0001259)body weight (CMO:0000012)396127817115665732Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)364655305115665732Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
1582252Sual1Serum uric acid level QTL 13.40.0123blood uric acid amount (VT:0010302)blood uric acid level (CMO:0000501)396127817102200699Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1581546Pur13Proteinuria QTL 132.930.0335total urine protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
1581568Rf53Renal function QTL 53total urine protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)373376539118376539Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)341874578104104347Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
2302273Gluco35Glucose level QTL 355.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)380800231114297550Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)33035677398535386Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)391797474136797474Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat

Genetic Models
This gene Bdnf is modified in the following models/strains
miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mirlet7drno-let-7d-5pMirtarbaseexternal_infoWestern blot;qRT-PCRNon-Functional MTI19703567
Mir376brno-miR-376b-5pMirtarbaseexternal_infoWestern blot//Luciferase reporter assayFunctional MTI22396777
Mir134rno-miR-134-5pMirtarbaseexternal_infoMicroarrayFunctional MTI (Weak)18258830

Predicted Target Of
Summary Value
Count of predictions:424
Count of miRNA genes:216
Interacting mature miRNAs:297
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (
For more information about miRGate, see PMID:25858286 or access the full paper here.