Ankrd63 (ankyrin repeat domain 63) - Rat Genome Database

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Gene: Ankrd63 (ankyrin repeat domain 63) Rattus norvegicus
Analyze
Symbol: Ankrd63
Name: ankyrin repeat domain 63
RGD ID: 1595953
Description: Orthologous to human ANKRD63 (ankyrin repeat domain 63); INTERACTS WITH fenvalerate; paracetamol; trichloroethene.
Type: protein-coding
RefSeq Status: INFERRED
Previously known as: ankyrin repeat domain-containing protein 63; LOC691770; similar to Ankyrin repeat domain-containing protein 28
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83126,129,069 - 126,133,891 (-)NCBIGRCr8
mRatBN7.23105,675,148 - 105,679,970 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3105,663,638 - 105,682,404 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3109,348,012 - 109,352,839 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03117,943,576 - 117,948,403 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03115,603,938 - 115,608,765 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03110,488,092 - 110,496,876 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3110,491,226 - 110,492,398 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03117,029,008 - 117,038,164 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43105,196,986 - 105,198,158 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3104,589,553 - 104,598,334 (-)NCBICelera
Cytogenetic Map3q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Ankrd63
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83126,129,069 - 126,133,891 (-)NCBIGRCr8
mRatBN7.23105,675,148 - 105,679,970 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3105,663,638 - 105,682,404 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3109,348,012 - 109,352,839 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03117,943,576 - 117,948,403 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03115,603,938 - 115,608,765 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03110,488,092 - 110,496,876 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3110,491,226 - 110,492,398 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03117,029,008 - 117,038,164 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43105,196,986 - 105,198,158 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3104,589,553 - 104,598,334 (-)NCBICelera
Cytogenetic Map3q35NCBI
ANKRD63
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381540,278,372 - 40,283,064 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1540,278,372 - 40,283,064 (-)EnsemblGRCh38hg38GRCh38
GRCh371540,570,573 - 40,575,265 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361538,360,937 - 38,362,079 (-)NCBINCBI36Build 36hg18NCBI36
Celera1517,339,637 - 17,340,779 (-)NCBICelera
Cytogenetic Map15q15.1NCBI
HuRef1517,416,603 - 17,417,745 (-)NCBIHuRef
CHM1_11540,693,611 - 40,694,753 (-)NCBICHM1_1
T2T-CHM13v2.01538,085,289 - 38,089,977 (-)NCBIT2T-CHM13v2.0
Ankrd63
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392118,529,584 - 118,534,444 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2118,529,584 - 118,534,444 (-)EnsemblGRCm39 Ensembl
GRCm382118,699,103 - 118,703,963 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2118,699,103 - 118,703,963 (-)EnsemblGRCm38mm10GRCm38
MGSCv372118,524,839 - 118,529,699 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362118,390,542 - 118,395,404 (-)NCBIMGSCv36mm8
MGSCv362119,646,125 - 119,650,987 (-)NCBIMGSCv36mm8
Celera2119,853,410 - 119,858,268 (-)NCBICelera
Cytogenetic Map2E5NCBI
cM Map259.43NCBI
Ankrd63
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554167,212,413 - 7,216,526 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554167,212,413 - 7,216,526 (-)NCBIChiLan1.0ChiLan1.0
ANKRD63
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21629,512,374 - 29,517,350 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11533,663,804 - 33,668,781 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01519,212,457 - 19,217,434 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11537,467,417 - 37,471,486 (-)NCBIpanpan1.1PanPan1.1panPan2
ANKRD63
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1307,465,387 - 7,468,382 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl307,466,081 - 7,467,229 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha307,518,697 - 7,521,544 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0307,590,571 - 7,593,421 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl307,591,913 - 7,593,061 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1307,515,123 - 7,517,971 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0307,621,483 - 7,623,924 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0307,750,061 - 7,752,502 (-)NCBIUU_Cfam_GSD_1.0
Ankrd63
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864085,900,015 - 85,905,674 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364713,751,068 - 3,752,234 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364713,751,068 - 3,752,234 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANKRD63
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1131,034,252 - 131,035,406 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11131,032,619 - 131,040,348 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21146,279,776 - 146,285,973 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ANKRD63
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12642,732,737 - 42,736,964 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2642,732,823 - 42,733,968 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604898,227,413 - 98,232,227 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ankrd63
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248047,588,025 - 7,589,182 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248047,585,240 - 7,589,913 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:95
Count of miRNA genes:68
Interacting mature miRNAs:74
Transcripts:ENSRNOT00000056450
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)396509147141509147Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)373592512136118980Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
1582216Bw65Body weight QTL 656.3body mass (VT:0001259)body weight (CMO:0000012)3122654702136118980Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)349872657138829559Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582219Bw63Body weight QTL 633.80.001body mass (VT:0001259)body weight (CMO:0000012)3116582412136118980Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)385062224136118980Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)385062224136118980Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)381425008141509147Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)370845569136091483Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)393829559138829559Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)3112250810157250810Rat
2302273Gluco35Glucose level QTL 355.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)3101255536134750886Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)396509147141509147Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)3117537367162537367Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3125116475170116475Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3110225882155225882Rat
631200Cm25Cardiac mass QTL 254.80.0001heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)381541464126563126Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)390755164141509147Rat
5686842Rf59Renal function QTL 59urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)3122395989167395989Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)398651826167012663Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)3125814931139636791Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3110634702155634702Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)3116188400161188400Rat

Markers in Region
RH143470  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23105,676,679 - 105,676,789 (+)MAPPERmRatBN7.2
Rnor_6.03110,489,625 - 110,489,734NCBIRnor6.0
Rnor_5.03117,030,542 - 117,030,651UniSTSRnor5.0
RGSC_v3.43105,195,385 - 105,195,494UniSTSRGSC3.4
Celera3104,591,086 - 104,591,195UniSTS
RH 3.4 Map3913.5UniSTS
Cytogenetic Map3q35UniSTS
RH139578  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23105,675,279 - 105,675,474 (+)MAPPERmRatBN7.2
Rnor_6.03110,488,225 - 110,488,419NCBIRnor6.0
Rnor_5.03117,029,142 - 117,029,336UniSTSRnor5.0
RGSC_v3.43105,193,985 - 105,194,179UniSTSRGSC3.4
Celera3104,589,686 - 104,589,880UniSTS
RH 3.4 Map3913.5UniSTS
Cytogenetic Map3q35UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 10 19 78 45 46 17 25 17 6 113 63 58 16 26 29

Sequence


Ensembl Acc Id: ENSRNOT00000056450   ⟹   ENSRNOP00000053288
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl3110,491,226 - 110,492,398 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108588   ⟹   ENSRNOP00000087166
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3105,663,638 - 105,682,404 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109172   ⟹   ENSRNOP00000089504
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3105,663,638 - 105,682,404 (-)Ensembl
RefSeq Acc Id: NM_001399655   ⟹   NP_001386584
RefSeq Status: INFERRED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83126,129,069 - 126,133,891 (-)NCBI
mRatBN7.23105,675,148 - 105,679,970 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001386584 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000087166.1
  ENSRNOP00000089504.1
Ensembl Acc Id: ENSRNOP00000053288   ⟸   ENSRNOT00000056450
Ensembl Acc Id: ENSRNOP00000087166   ⟸   ENSRNOT00000108588
Ensembl Acc Id: ENSRNOP00000089504   ⟸   ENSRNOT00000109172
RefSeq Acc Id: NP_001386584   ⟸   NM_001399655
- UniProtKB: A0A8I6AAG2 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZKY6-F1-model_v2 AlphaFold D3ZKY6 1-390 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1595953 AgrOrtholog
BioCyc Gene G2FUF-48242 BioCyc
Ensembl Genes ENSRNOG00000042446 Ensembl
  ENSRNOG00000062526 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000108588.1 UniProtKB/TrEMBL
  ENSRNOT00000109172.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
NCBI Gene 691770 ENTREZGENE
PANTHER ANKYRIN REPEAT FAMILY A UniProtKB/TrEMBL
  REPEAT PROTEIN, PUTATIVE-RELATED UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/TrEMBL
PhenoGen Ankrd63 PhenoGen
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000042446 RatGTEx
  ENSRNOG00000062526 RatGTEx
SMART ANK UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/TrEMBL
UniProt A0A8I6AAG2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Ankrd63  ankyrin repeat domain 63  Ankrd63  ankyrin repeat domain 63  Data merged from RGD:149736222 737654 PROVISIONAL
2021-08-09 Ankrd63  ankyrin repeat domain 63      Symbol and Name status set to provisional 45752 PROVISIONAL
2011-06-10 Ankrd63  ankyrin repeat domain 63  LOC691770  similar to Ankyrin repeat domain-containing protein 28  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC691770  similar to Ankyrin repeat domain-containing protein 28  LOC687982  similar to Ankyrin repeat domain-containing protein 28  Data merged from RGD:1594869 1643240 APPROVED
2006-11-20 LOC691770  similar to Ankyrin repeat domain-containing protein 28      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC687982  similar to Ankyrin repeat domain-containing protein 28      Symbol and Name status set to provisional 70820 PROVISIONAL