Gene: Traf6 (TNF receptor associated factor 6) Rattus norvegicus
Symbol: Traf6
Name: TNF receptor associated factor 6
Description: ENCODES a protein that exhibits histone deacetylase binding (ortholog); identical protein binding (ortholog); mitogen-activated protein kinase kinase kinase binding (ortholog); INVOLVED IN cytokine-mediated signaling pathway; interleukin-1-mediated signaling pathway; JNK cascade; PARTICIPATES IN interleukin-1 signaling pathway; nuclear factor kappa B signaling pathway; p38 MAPK signaling pathway; ASSOCIATED WITH Arthritis, Rheumatoid (ortholog); Coronary Artery Disease (ortholog); FOUND IN protein complex; CD40 receptor complex (ortholog); cytoplasm (ortholog); INTERACTS WITH 2,6-dinitrotoluene; bisphenol A; C60 fullerene
Type: protein-coding
Also known as: E3 ubiquitin-protein ligase TRAF6; LOC311245; RING-type E3 ubiquitin transferase TRAF6; TNF receptor-associated factor 6; TNF receptor-associated factor 6, E3 ubiquitin protein ligase
Homo sapiens (human) : TRAF6 (TNF receptor associated factor 6)  HGNC  AGR
Mus musculus (house mouse) : Traf6 (TNF receptor-associated factor 6)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Traf6 (TNF receptor associated factor 6)
Pan paniscus (bonobo/pygmy chimpanzee) : TRAF6 (TNF receptor associated factor 6)
Canis lupus familiaris (dog) : TRAF6 (TNF receptor associated factor 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Traf6 (TNF receptor associated factor 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0391,252,829 - 91,271,607 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0397,912,482 - 97,935,027 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4386,827,582 - 86,847,408 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1386,728,165 - 86,742,912 (+)NCBI
Celera387,069,225 - 87,089,051 (+)NCBICelera
Cytogenetic Map3q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Traf6
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1306853
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2017-12-19
Status: ACTIVE