Fgf7 (fibroblast growth factor 7)

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Gene: Fgf7 (fibroblast growth factor 7) Rattus norvegicus

Analyze

Symbol:

Fgf7

Name:

fibroblast growth factor 7

RGD ID:

61805

Description:

Exhibits growth factor activity; heparin binding activity; and type 2 fibroblast growth factor receptor binding activity. Involved in several processes, including animal organ development; phosphatidylcholine biosynthetic process; and surfactant homeostasis. Localizes to extracellular space. Orthologous to human FGF7 (fibroblast growth factor 7); PARTICIPATES IN glypican signaling pathway; melanoma pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2-amino-2-deoxy-D-glucopyranose; acrylamide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

FGF-7; HBGF-7; heparin-binding growth factor 7; keratinocyte growth factor; Keratinocyte Growth Factor Fgf-7; Kgf; KGF/FGF7

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	FGF7 (fibroblast growth factor 7)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Fgf7 (fibroblast growth factor 7)	HGNC	Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Fgf7 (fibroblast growth factor 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LOC100995394 (uncharacterized LOC100995394)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	FGF7 (fibroblast growth factor 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Fgf7 (fibroblast growth factor 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	FGF7 (fibroblast growth factor 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	FGF7 (fibroblast growth factor 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Fgf7 (fibroblast growth factor 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Fgf7 (fibroblast growth factor 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Homo sapiens (human):	FGF7 (fibroblast growth factor 7)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Danio rerio (zebrafish):	fgf7 (fibroblast growth factor 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Drosophila melanogaster (fruit fly):	bnl	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	let-756	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	3	118,315,859 - 118,368,464 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	118,317,761 - 118,366,872 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	124,840,157 - 124,892,611 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	113,468,427 - 113,517,538 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	3	113,373,999 - 113,423,111 (+)	NCBI
Celera	3	112,134,799 - 112,183,941 (+)	NCBI		Celera
Cytogenetic Map	3	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

cervical squamous cell carcinoma (ISO)

cleft lip (ISO)

cleft palate (ISO)

endometrial carcinoma (ISO)

Gingival Hyperplasia (ISO)

leiomyoma (ISO)

liver cirrhosis (ISO)

Lung Injury (ISO)

Mammary Neoplasms, Experimental (ISO)

ovarian cancer (ISO)

prostate cancer (ISO)

prostatic hypertrophy (ISO)

pulmonary fibrosis (ISO)

Reperfusion Injury (ISO)

severe acute respiratory syndrome (ISO)

Spontaneous Abortions (ISO)

squamous cell carcinoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1-dichloroethene (ISO)

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-amino-2-deoxy-D-glucopyranose (EXP)

3,3',5-triiodo-L-thyronine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

3-methylcholanthrene (ISO)

5-azacytidine (ISO)

5-fluorouracil (ISO)

acrylamide (EXP)

aldehydo-D-glucosamine (EXP)

aldehydo-D-glucose (ISO)

ammonium chloride (EXP)

anthra[1,9-cd]pyrazol-6(2H)-one (ISO)

antirheumatic drug (ISO)

ANTU (EXP)

arabinoxylan (ISO)

Aroclor 1254 (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

azathioprine (ISO)

benzo[a]pyrene (ISO)

beta-D-glucosamine (EXP)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP,ISO)

boric acid (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

cholesterol (EXP,ISO)

cisplatin (ISO)

cyclosporin A (ISO)

D-glucose (ISO)

dermatan sulfate (ISO)

dexamethasone (ISO)

diarsenic trioxide (ISO)

doxorubicin (EXP)

fluoranthene (ISO)

geldanamycin (ISO)

glucose (ISO)

graphite (EXP)

heparan sulfate (ISO)

heparin (EXP)

hyaluronic acid (EXP)

hydrogen peroxide (ISO)

indometacin (EXP)

lead(0) (ISO)

lead(2+) (ISO)

lipopolysaccharide (ISO)

LY294002 (ISO)

medroxyprogesterone acetate (ISO)

methotrexate (ISO)

N-acetyl-L-cysteine (ISO)

N-nitrosodiethylamine (EXP)

naphthalene (ISO)

nickel atom (ISO)

nifedipine (ISO)

nitrofen (EXP)

oxaliplatin (EXP)

paclitaxel (ISO)

PCB138 (ISO)

pentanal (ISO)

phenethyl caffeate (EXP)

phorbol 13-acetate 12-myristate (ISO)

pioglitazone (ISO)

prostaglandin E2 (EXP)

quercetin (ISO)

resveratrol (ISO)

SB 203580 (ISO)

shikimic acid (ISO)

sirolimus (ISO)

sodium atom (ISO)

sodium aurothiomalate (ISO)

sunitinib (ISO)

suramin (ISO)

tamoxifen (ISO)

tetrachloromethane (EXP,ISO)

tetraphene (ISO)

thioacetamide (EXP)

topotecan (EXP)

trichloroethene (ISO)

trimellitic anhydride (ISO)

valproic acid (ISO)

wortmannin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

actin cytoskeleton reorganization (IEA,ISO)

animal organ morphogenesis (IBA)

branching involved in salivary gland morphogenesis (IEA,ISO)

cell differentiation (IBA)

fibroblast growth factor receptor signaling pathway (IBA,IEA,ISO)

hair follicle morphogenesis (IEA,ISO)

lung development (IBA,IMP)

mesenchymal cell proliferation (IEA,ISO)

ovarian follicle development (IMP)

phosphatidylcholine biosynthetic process (IMP)

phospholipid biosynthetic process (IMP)

positive chemotaxis (IBA,IEA,ISO)

positive regulation of cell division (IEA)

positive regulation of cell population proliferation (IBA,ISO)

positive regulation of epithelial cell proliferation (IBA,IDA,IMP,ISO)

positive regulation of epithelial cell proliferation involved in lung morphogenesis (IEA,ISO)

positive regulation of gene expression (IBA)

positive regulation of keratinocyte migration (IEA,ISO)

positive regulation of keratinocyte proliferation (IEA,ISO)

positive regulation of peptidyl-tyrosine phosphorylation (IBA,IEA,ISO)

positive regulation of protein phosphorylation (IBA)

positive regulation of transcription, DNA-templated (IBA,IEA,ISO)

protein localization to cell surface (IEA,ISO)

regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling (IEA,ISO)

regulation of cell migration (IBA)

secretion by lung epithelial cell involved in lung growth (IEA,ISO)

surfactant homeostasis (IMP)

wound healing (IDA)

Cellular Component

cytoplasm (IBA)

extracellular region (IEA,ISO)

extracellular space (IBA,IDA)

Golgi apparatus (IEA,ISO)

Molecular Function

chemoattractant activity (IEA,ISO)

fibroblast growth factor receptor binding (IBA,IEA)

growth factor activity (IBA,IEA,IMP)

heparin binding (IDA)

protein binding (ISO)

type 2 fibroblast growth factor receptor binding (IBA,IDA)

Molecular Pathway Annotations Click to see Annotation Detail View

glypican signaling pathway (ISO)

melanoma pathway (IEA)

mitogen activated protein kinase signaling pathway (IEA)

References

References - curated


1.	Adamson IY and Bakowska J, Exp Lung Res. 2001 Oct-Nov;27(7):605-16.
2.	Boget S, etal., Farmaco. 2001 May-Jul;56(5-7):467-9.
3.	Chelly N, etal., Endocrinology 2001 May;142(5):1814-9.
4.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5.	GOA data from the GO Consortium
6.	Ishiwata T, etal., Exp Mol Pathol 2002 Dec;73(3):181-90.
7.	Kezele P, etal., Biol Reprod. 2005 Nov;73(5):967-73. Epub 2005 Jul 6.
8.	Kitsberg DI and Leder P, Oncogene. 1996 Dec 19;13(12):2507-15.
9.	Kong SL, etal., Virus Res. 2009 Nov;145(2):260-9. Epub 2009 Jul 25.
10.	Leung HY, etal., Oncogene. 1997 Aug 28;15(9):1115-20.
11.	Litovkin KV, etal., Exp Oncol. 2008 Jun;30(2):106-11.
12.	Luo Y, etal., Biochemistry. 1998 Nov 24;37(47):16506-15.
13.	Manavi M, etal., Gynecol Oncol. 2007 May;105(2):418-26. Epub 2007 Feb 15.
14.	Mason RJ, etal., J Clin Invest 2003 Jul;112(2):244-55.
15.	MGD data from the GO Consortium
16.	NCBI rat LocusLink and RefSeq merged data July 26, 2002
17.	Pandey J and Wendell DL, Mamm Genome. 2006 Jan;17(1):49-57. Epub 2006 Jan 13.
18.	Parrott JA, etal., Mol Cell Endocrinol. 2000 Sep 25;167(1-2):77-87.
19.	Pereira CT, etal., J Surg Res. 2007 May 15;139(2):222-8. Epub 2007 Feb 9.
20.	Pipeline to import KEGG annotations from KEGG into RGD
21.	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
22.	RGD automated data pipeline
23.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
24.	RGD automated import pipeline for gene-chemical interactions
25.	Siegfried S, etal., Cancer. 1997 Mar 15;79(6):1166-71.
26.	Yan G, etal., Mol Endocrinol. 1992 Dec;6(12):2123-8.
27.	Zhao H, etal., Biochem Biophys Res Commun 2002 Mar 29;292(2):482-91.

Additional References at PubMed

PMID:1869483	PMID:8663044	PMID:9740653	PMID:10541313	PMID:11023837	PMID:11098134	PMID:11493558	PMID:12581741	PMID:12837279	PMID:12861530	PMID:14506240	PMID:14697353
PMID:15690149	PMID:15806171	PMID:17187775	PMID:17392324	PMID:17394208	PMID:17449030	PMID:17872496	PMID:18091341	PMID:18559345	PMID:19266047	PMID:20069574	PMID:21136143
PMID:21436609	PMID:26894526	PMID:27035760	PMID:30816491	PMID:30858037	PMID:30894415	PMID:31017714

Genomics

Comparative Map Data

Fgf7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	3	118,315,859 - 118,368,464 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	118,317,761 - 118,366,872 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	124,840,157 - 124,892,611 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	113,468,427 - 113,517,538 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	3	113,373,999 - 113,423,111 (+)	NCBI
Celera	3	112,134,799 - 112,183,941 (+)	NCBI		Celera
Cytogenetic Map	3	q36	NCBI

FGF7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	15	49,423,237 - 49,488,775 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38.p13 Ensembl	15	49,423,178 - 49,488,775 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	15	49,423,242 - 49,488,775 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	15	49,715,375 - 49,779,523 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	47,502,751 - 47,566,815 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	15	47,502,750 - 47,566,815	NCBI
Celera	15	26,608,551 - 26,672,713 (+)	NCBI
Cytogenetic Map	15	q21.2	NCBI
HuRef	15	26,547,279 - 26,611,441 (+)	NCBI		HuRef
CHM1_1	15	49,833,504 - 49,897,659 (+)	NCBI		CHM1_1

Fgf7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	125,876,578 - 125,933,105 (+)	NCBI	GRCm39		mm39
GRCm38	2	126,034,658 - 126,091,185 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	126,034,658 - 126,091,185 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	125,860,394 - 125,916,921 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	2	125,726,225 - 125,781,966 (+)	NCBI			mm8
Celera	2	127,270,998 - 127,337,627 (+)	NCBI		Celera
Cytogenetic Map	2	F1	NCBI

Fgf7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955409	4,632,858 - 4,686,860 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955409	4,633,542 - 4,686,768 (-)	NCBI	ChiLan1.0	ChiLan1.0

LOC100995394
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	15	46,702,119 - 46,795,923 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	46,702,119 - 46,770,163 (+)	Ensembl	panpan1.1		panPan2

FGF7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	30	15,555,266 - 15,606,521 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	30	15,555,016 - 15,608,230 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Fgf7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936471	11,636,733 - 11,692,782 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FGF7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	122,215,878 - 122,542,224 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	122,215,878 - 122,278,705 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	135,926,619 - 135,928,879 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FGF7
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	33,802,349 - 33,867,743 (-)	NCBI
ChlSab1.1 Ensembl	26	33,802,328 - 33,867,333 (-)	Ensembl

Fgf7
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624731	10,413,715 - 10,468,660 (-)	NCBI

Position Markers

D3Mco11

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	3	118,335,462 - 118,335,705	NCBI	Rnor6.0
Rnor_5.0	3	124,859,156 - 124,859,399	UniSTS	Rnor5.0
RGSC_v3.4	3	113,486,127 - 113,486,371	RGD	RGSC3.4
RGSC_v3.4	3	113,486,128 - 113,486,371	UniSTS	RGSC3.4
RGSC_v3.1	3	113,391,700 - 113,391,944	RGD
Celera	3	112,152,539 - 112,152,780	UniSTS
Cytogenetic Map	3	q36	UniSTS

FGF7

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	3	118,365,609 - 118,366,797	NCBI	Rnor6.0
Rnor_5.0	3	124,889,756 - 124,890,944	UniSTS	Rnor5.0
RGSC_v3.4	3	113,516,275 - 113,517,463	UniSTS	RGSC3.4
Celera	3	112,182,678 - 112,183,866	UniSTS
Cytogenetic Map	3	q36	UniSTS

FGF7

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	3	118,365,613 - 118,366,869	NCBI	Rnor6.0
Rnor_5.0	3	124,889,760 - 124,891,016	UniSTS	Rnor5.0
RGSC_v3.4	3	113,516,279 - 113,517,535	UniSTS	RGSC3.4
Celera	3	112,182,682 - 112,183,938	UniSTS
Cytogenetic Map	3	q36	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	10639528	127023997	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	10639528	127023997	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	30114912	123700444	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	30846101	172879276	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	39248391	140271184	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	43295930	163640485	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	43295930	163640485	Rat
1581503	Cm58	Cardiac mass QTL 58	2.7	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	45406058	127023997	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	45406058	177699992	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	48561928	155263151	Rat
631665	Bw8	Body weight QTL 8	5.5		body mass (VT:0001259)	body weight (CMO:0000012)	3	51821836	124513579	Rat
724523	Tsu1	Thymus enlargement suppressive QTL 1	3.84		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	3	51822008	120917851	Rat
1582218	Bw74	Body weight QTL 74	3.9	0.0021	body mass (VT:0001259)	body weight (CMO:0000012)	3	54630948	119830094	Rat
1582238	Bw68	Body weight QTL 68	3.2	0.0064	body mass (VT:0001259)	body weight (CMO:0000012)	3	54630948	119830094	Rat
1582239	Epfw1	Epididymal fat weight QTL 1	4.5	0.0006	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	3	54630948	119830094	Rat
1581568	Rf53	Renal function QTL 53			total urine protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	3	58204463	170534769	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	61241033	165369047	Rat
1300111	Rf12	Renal function QTL 12	3.78		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	62922868	127023997	Rat
1582221	Kidm30	Kidney mass QTL 30	3.5	0.0008	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	3	66711607	119830094	Rat
1582210	Bw71	Body weight QTL 71	3.3	0.0012	body mass (VT:0001259)	body weight (CMO:0000012)	3	66711607	119830094	Rat
12879848	Bw181	Body weght QTL 181		0.015	body mass (VT:0001259)	body weight (CMO:0000012)	3	72672290	127023997	Rat
2301414	Kidm37	Kidney mass QTL 37		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	72973445	127023997	Rat
1600376	Arunc5	Aerobic running capacity QTL 5		0.21	exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	3	78700444	123700444	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	total urine protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	81136227	154416635	Rat
2302273	Gluco35	Glucose level QTL 35	5.3	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	83817637	119509260	Rat
7387306	Bw124	Body weight QTL 124	3.2	0.0003	body mass (VT:0001259)	body weight (CMO:0000012)	3	88910015	133910015	Rat
631649	Bp123	Blood pressure QTL 123	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	94788365	139788365	Rat
8694437	Bw167	Body weight QTL 167	22.46	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	3	97009185	142009185	Rat
631841	Niddm39	Non-insulin dependent diabetes mellitus QTL 39	3.36		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	99465522	168732722	Rat
1582219	Bw63	Body weight QTL 63	3.8	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	3	100730984	119830094	Rat
724532	Cm17	Cardiac mass QTL 17	2		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	3	101058963	146058963	Rat
2293087	Iddm27	Insulin dependent diabetes mellitus QTL 27	2.68		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	102152812	155263151	Rat
1354611	Despr2	Despair related QTL 2	3.03	0.0028	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	3	102466149	147466149	Rat
2312659	Slep7	Serum leptin concentration QTL 7		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	3	103141814	176418101	Rat
2312670	Bw94	Body weight QTL 94		0.01	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	3	103141814	176418101	Rat
2312673	Scl63	Serum cholesterol level QTL 63		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	103141814	176418101	Rat
2302373	Gluco39	Glucose level QTL 39	5.01		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	3	103141944	170934860	Rat
1582216	Bw65	Body weight QTL 65	6.3		body mass (VT:0001259)	body weight (CMO:0000012)	3	106900427	119830094	Rat
619618	Rf3	Renal disease susceptibility QTL 3	6.5	0.001	urine albumin amount (VT:0002871)	urine albumin excretion rate to body weight ratio (CMO:0001270)	3	114376250	159376250	Rat
1331758	Bp207	Blood pressure QTL 207	2.848		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	117303473	141971336	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	79
Count of miRNA genes:	73
Interacting mature miRNAs:	77
Transcripts:	ENSRNOT00000012700
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	1		5		11		3	3			6	11	3
Low	2	33	19	8	8	8	5	8	25	31	28		5
Below cutoff		6	11	11		11			35	4	7

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_022182	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006234903	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017591518	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAHX01024880	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AAHX01024881	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC139594	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF295300	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X56551	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X95743	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000012700 ⟹ ENSRNOP00000012700

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	3	118,317,761 - 118,366,872 (+)	Ensembl

RefSeq Acc Id:

NM_022182 ⟹ NP_071518

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	118,317,761 - 118,366,872 (+)	NCBI
Rnor_5.0	3	124,840,157 - 124,892,611 (+)	NCBI
RGSC_v3.4	3	113,468,427 - 113,517,538 (+)	RGD
Celera	3	112,134,799 - 112,183,941 (+)	RGD

Sequence:

show sequence

CAATCTACAATTCACAGATAGGAGGAGGCCCATGACCTAGGAGTAGCGATCAACTCAAGGTCCA
GTTCTCATTATGTTATTCATGGACACCCGGGGCACTGCTCTATAATGCGCAAATGGATACTGAC
ACGGATCCTGCCGACTCCGCTCTACAGACCGTGCTTCCACCTCGTCTGTCTTGTGGGCACCATA
TCTTTAGCTTGCAATGACATGAGTCCAGAGCAGACGGCCACGAGCGTGAACTGTTCTAGCCCCG
AGCGACACACGAGAAGTTATGACTACATGGAAGGAGGGGATATAAGGGTGAGGAGACTGTTCTG
TCGCACCCAGTGGTACCTGAGGATTGACAAACGAGGCAAAGTGAAAGGGACCCAGGAGATGAGG
AACAGCTACAACATCATGGAAATCATGACTGTGGCAGTTGGAATTGTGGCAATCAAAGGGGTGG
AAAGTGAATACTATCTTGCCATGAACAAACAAGGGGAACTCTATGCAAAGAAAGAATGCAATGA
GGATTGCAACTTCAAAGAACTGATTCTGGAAAACCATTACAACACCTCTGCATCAGCTAAATGG
ACACACAGCGGAGGGGAAATGTTCGTGGCCTTAAATCAAAAGGGGCTTCCTGTCAAAGGGAAGA
AAACGAAGAAAGAACAAAAAACGGCCCACTTTCTTCCTATGGCAATAACTTAA

hide sequence

RefSeq Acc Id:

XM_006234903 ⟹ XP_006234965

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	118,315,859 - 118,368,464 (+)	NCBI
Rnor_5.0	3	124,840,157 - 124,892,611 (+)	NCBI

Sequence:

show sequence

TGTGCATGTGTGTGTGTGTTGCAGGTACATGGAAAAGAGAATTTTAACATATGTTTTCTTAAAT
ACTCATTTAGATTGGTGATACAATGGCTCCATTCTAAATATAAAATACAATTACAATCTTGCTC
AGTACAGGATAGGCACAGACTCATTTTGGAAAGCAAAAGGGCTCTCCTATGTCCATTAGCTATT
GGCCTTACAATTACTGGATTTATCAGTTATTTTTTTTATGCTATTGCTCTCAGGGAGGCACAAG
TCAAACACCAAGGCACAAACCATTTTTCTAAAAGAATGATAGTTTTGCAAAGCATGTGTCCTTT
GTTTCTGTGAGTCGTCTGTTGGAATAAATCACAAGATGGGATGCTAAAATGACAGCACAGCACT
GGTCTGATTAGGCATGGCCATTGATTTGATACCTGAAGCAGCAGCTGGGCCACAGGGAAGTAAG
TGACTGATCCAAGGCCACATTGTTTGTTAGAATCCCAGTCTAATAAGAAACTAAGACTCACACA
CAATGGTGCACTATCTGAGAAAAGGTATGTTCTTGCCTAGGAATACCTACTCTCAGCCCTGAGC
CTGCTGCTCTAGTACTCTGAGTATGAAGGAATATGAACTTACCTCCCCAGTGTATTGTAAAGAC
CATCTAACTATTGAAAGCCCTTCTATATGTTCTAGGAAATGTTTTTCACAGACTGTACAGCTTC
TGTGCTTAAAAGGGCTAACACTTCCCTTTCTCTATGTAAGTGCTTGAGAATCAGAGGTCTGTTT
CCACAGAGCGGATGCCCACTTGTGGATTTAAACCAAAGCCGTGTCCATAGCTCCCCCTTATGAC
CACTCAACGGTACACAAGCCTTCATCTATTCCTGCTGTTTCAGACAACGAACAGCTCACTGGTT
AAGCTTTAATTGCTTCCAATGAGGTCAGCAAAGGTATTTATTGAAAATCTCTGAATAAAAGGGT
CCACGCACTCACACAAGCGCACGCGCTCACACACGGAGAAAATCCTTTTGCCTGTTGATTTATG
GAAACAATTATGATTCTGCTGGAGGACTTCTCAGCTGAGAAATAGTTTGTAGCTACAGTAGAGG
CTCAAGTTGCACCAGGCAGACAGCAGACACGGAACTCTTGTGTACCCAGCTGTTCCAAACAGAA
CAAAAGTCAAGCAGCAAATGCACGGCAGCAACTGGCCTTGTTCCGACCGGTTTCTACAAGGATA
TACCCATCAACTGTGCTCCTGAAGAAGGAATCCTCTTATTGGCATCAGAAGCTAAAAGATAAGG
TTAACAGTTTGGAAAGAGCGAGGACCTTTTCTCAAATCAATCTCCAGTTCACAGACAGGAGGAG
GCCCATGACCTAGGAGTAGCGATCAACTCAAGGTCCAGTTCTCATTATGTTATTCATGGACACC
CGGGGCACTGCTCTATAATGCGCAAATGGATACTGACACGGATCCTGCCGACTCCGCTCTACAG
ATCGTGCTTCCACCTCGTCTGTCTTGTGGGCACCATATCTTTAGCTTGCAATGACATGAGTCCA
GAGCAGACGGCCACGAGCGTGAACTGTTCTAGCCCCGAGCGACACACGAGAAGTTATGACTACA
TGGAAGGAGGGGATATAAGGGTGAGGAGACTGTTCTGTCGCACCCAGTGGTACCTGAGGATTGA
CAAACGAGGCAAAGTGAAAGGGACCCAGGAGATGAGGAACAGCTACAACATCATGGAAATCAGG
ACTGTGGCAGTTGGAATTGTGGCAATCAAAGGGGTGGAAAGTGAATACTATCTTGCCATGAACA
AAGAAGGGAAACTCTATGCAAAGAAAGAATGCAATGAGGATTGCAACTTCAAAGAACTGATTCT
GGAAAACCATTACAACACCTATGCATCAGCTAAATGGACACACAGCGGAGGGGAAATGTTCGTG
GCCTTAAATCAAAAGGGGCTTCCTGTCAAAGGGAAGAAAACGAAGAAAGAACAAAAAACGGCCC
ATTTTCTTCCCATGGCAATAACCTAAGCATACAGGGTGTTTGAGAAACCAGTTTCACTCAGCAG
GGAGATTTATTTCCAGTGGACTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC
TCTCTCTAAGTAACCAAGAAAGGCTGGAAAACTACTGAAAAACCGATCAAGCTGGACTTGCGCA
TTTTTGTTTATTTTAAAAGACTGCATTAAAGAAAGATTTGAAGAATATACACAAAATTCAGATT
TAGTAAAAGTTGTAAAAAGTTGTAAAAGTGGTTGTACAATCATGATGTTAGTGACGTGATATTT
TTCTTAAGTTAATTTACCCTTAAGAGTATGTTAGATTTGACTATCTGATAATGAATATTTAATA
TCACTATCTGCTTATAAAATGGCTGCTATAATAATATTAATAATGCAGATGATGTTATATAAGG
TATGTCAGACCTAAAGGCTGCTGGGACGCTTTGTCAGATGATCAAGCCCCATACAAACTGTAGA
CGATGAGCAGTGTTTGAAAGCTTTCCAGAAAGAACTAAACTCCACTTCAACTCTATTCAGAAAA
GTGAATGTTCTCAACATTTTATTATAGAATACAATCTACAGGTGGTTTTACAAAATCATGCCTG
TCCTGATTAACGTGAAAAAAAATCCACTCAAATTGGAAAGGTATTGCTAACAGGATGCTTTAAA
AGTCTGTGTATGAAATAGCAATGATGATGATAATACTGCATTTCATCTTGCCACAAAGGAACAT
TTTATAATCCCTAAAAGTAAACTTCAGAAATCTTTACATTTTTTCAAGTAACATCTATCTTTTG
TATAATTCACATTTGGGAACACGACTTTCAGTAATGTTCTTCCCACAAATAATCATGCTTATTT
CCCTCTGTGATTACAGCATTAAACTCTACTTTAAGTTGTATTTGAATTTTATTGTTTTGTTATT
TAAGTTTTTGTTATTTATAAAGAAAAAAACTTAAGAAGCTGTATCTGTTTCATATGCTTTTAAT
TTCAAGGGGACAACAAACCCGTCTGGCTGCACTGCAGATGTCTCCTCCCCTGGTGGCTGACACC
AAGTCTAGCACACAACACTTGGCTAGCAAGTGCTGGATGGCAGACAAAAACGACAGGCTGCAGC
CATGCCTCCAATAGATGTCTCATAGTGAACGATACGAATATGTGGGAAAGATTTCACACAACGC
TCATGCCAATGAATTTGGATCATATAAGTAAAAGAAATCAAAGTATTTAGTGAGGACATATTTT
TGAAAGTAGGCATATTTAAAGTTAGCAATTTGATCATCTTTAGAAGTTTCTGCCATACAAAATA
TGCCAACTTTGAAATGTCAAGAGTAAAACCCCAAATAGAGGTTGTAGTCAGGGTACAGGGCCCT
AAACACCTTGAGGCTTCAGGTCAGGCCACAGATAACAGGCTTAAAAAACACATGAACTTACTCC
ATAGTTCTGCCACCAGTGGATGCTGACAGAAATGTATATATACTTATGAAGGGAAGTGCAACAT
TTATTTAAATTGTTGGTATATTAATTAATGTGATATCAACTTCATAGTGGTTGTCATTAAAGTT
TCTTTATATTACATACAA

hide sequence

RefSeq Acc Id:

XM_017591518 ⟹ XP_017447007

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	118,315,859 - 118,368,464 (+)	NCBI

Sequence:

show sequence

TGTGCATGTGTGTGTGTGTTGCAGGTACATGGAAAAGAGAATTTTAACATATGTTTTCTTAAAT
ACTCATTTAGATTGGTGATACAATGGCTCCATTCTAAATATAAAATACAATTACAATCTTGCTC
AGTACAGGATAGGCACAGACTCATTTTGGAAAGCAAAAGGGCTCTCCTATGTCCATTAGCTATT
GGCCTTACAATTACTGGATTTATCAGTTATTTTTTTTATGCTATTGCTCTCAGGGAGGCACAAG
TCAAACACCAAGGCACAAACCATTTTTCTAAAAGAATGATAGTTTTGCAAAGCATGTGTCCTTT
GTTTCTGTGAGTCGTCTGTTGGAATAAATCACAAGATGGGATGCTAAAATGACAGCACAGCACT
GGTCTGATTAGGCATGGCCATTGATTTGATACCTGAAGCAGCAGCTGGGCCACAGGGAAGTAAG
TGACTGATCCAAGGCCACATTGTTTGTTAGAATCCCAGTCTAATAAGAAACTAAGACTCACACA
CAATGGTGCACTATCTGAGAAAAGGTATGTTCTTGCCTAGGAATACCTACTCTCAGCCCTGAGC
CTGCTGCTCTAGTACTCTGAGTATGAAGGAATATGAACTTACCTCCCCAGTGTATTGTAAAGAC
CATCTAACTATTGAAAGCCCTTCTATATGTTCTAGGAAATGTTTTTCACAGACTGTACAGCTTC
TGTGCTTAAAAGGGCTAACACTTCCCTTTCTCTATGTAAGTGCTTGAGAATCAGAGGTCTGTTT
CCACAGAGCGGATGCCCACTTGTGGATTTAAACCAAAGCCGTGTCCATAGCTCCCCCTTATGAC
CACTCAACGGTACACAAGCCTTCATCTATTCCTGCTGTTTCAGACAACGAACAGCTCACTGGTT
AAGCTTTAATTGCTTCCAATGAGGTCAGCAAAGGTATTTATTGAAAATCTCTGAATAAAAGGGT
CCACGCACTCACACAAGCGCACGCGCTCACACACGGAGAAAATCCTTTTGCCTGTTGATTTATG
GAAACAATTATGATTCTGCTGGAGGACTTCTCAGCTGAGAAATAGTTTGTAGCTACAGTAGAGG
CTCAAGTTGCACCAGGCAGACAGCAGACACGGAACTCTTGTGTACCCAGCTGTTCCAAACAGAA
CAAGTAAGTTACTGTTATTTGTCTTTTAAACAATGCTGAATCTTTTCTGAAAGATTTTCTCTCT
CTATGGTTAGAGTACTGAGGGAGGGGTGGCTTTTTAGCTGTGTAAATATCTACAGAAATTGTGC
TGTAGTACGTATGGAAAGAGACGCTTGAAGTTCTCCAGGGCAATCCTGACACTTAACTTGAAAA
ATCTGGGCAGTTTCAGAGAAAATAATTATTAAGCACAAATGTAAAAGCGTATACTCATGGATCC
CAAGGAGAGTGTTTCAACTTTGTCGATAGTGGCTGTAAAACTCGATTTAACCCAATAGCTAAGT
CAAGCAGCAAATGCACGGCAGCAACTGGCCTTGTTCCGACCGGTTTCTACAAGGATATACCCAT
CAACTGTGCTCCTGAAGAAGGAATCCTCTTATTGGCATCAGAAGCTAAAAGATAAGGTTAACAG
TTTGGAAAGAGCGAGGACCTTTTCTCAAATCAATCTCCAGTTCACAGACAGGAGGAGGCCCATG
ACCTAGGAGTAGCGATCAACTCAAGGTCCAGTTCTCATTATGTTATTCATGGACACCCGGGGCA
CTGCTCTATAATGCGCAAATGGATACTGACACGGATCCTGCCGACTCCGCTCTACAGATCGTGC
TTCCACCTCGTCTGTCTTGTGGGCACCATATCTTTAGCTTGCAATGACATGAGTCCAGAGCAGA
CGGCCACGAGCGTGAACTGTTCTAGCCCCGAGCGACACACGAGAAGTTATGACTACATGGAAGG
AGGGGATATAAGGGTGAGGAGACTGTTCTGTCGCACCCAGTGGTACCTGAGGATTGACAAACGA
GGCAAAGTGAAAGGGACCCAGGAGATGAGGAACAGCTACAACATCATGGAAATCAGGACTGTGG
CAGTTGGAATTGTGGCAATCAAAGGGGTGGAAAGTGAATACTATCTTGCCATGAACAAAGAAGG
GAAACTCTATGCAAAGAAAGAATGCAATGAGGATTGCAACTTCAAAGAACTGATTCTGGAAAAC
CATTACAACACCTATGCATCAGCTAAATGGACACACAGCGGAGGGGAAATGTTCGTGGCCTTAA
ATCAAAAGGGGCTTCCTGTCAAAGGGAAGAAAACGAAGAAAGAACAAAAAACGGCCCATTTTCT
TCCCATGGCAATAACCTAAGCATACAGGGTGTTTGAGAAACCAGTTTCACTCAGCAGGGAGATT
TATTTCCAGTGGACTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT
AAGTAACCAAGAAAGGCTGGAAAACTACTGAAAAACCGATCAAGCTGGACTTGCGCATTTTTGT
TTATTTTAAAAGACTGCATTAAAGAAAGATTTGAAGAATATACACAAAATTCAGATTTAGTAAA
AGTTGTAAAAAGTTGTAAAAGTGGTTGTACAATCATGATGTTAGTGACGTGATATTTTTCTTAA
GTTAATTTACCCTTAAGAGTATGTTAGATTTGACTATCTGATAATGAATATTTAATATCACTAT
CTGCTTATAAAATGGCTGCTATAATAATATTAATAATGCAGATGATGTTATATAAGGTATGTCA
GACCTAAAGGCTGCTGGGACGCTTTGTCAGATGATCAAGCCCCATACAAACTGTAGACGATGAG
CAGTGTTTGAAAGCTTTCCAGAAAGAACTAAACTCCACTTCAACTCTATTCAGAAAAGTGAATG
TTCTCAACATTTTATTATAGAATACAATCTACAGGTGGTTTTACAAAATCATGCCTGTCCTGAT
TAACGTGAAAAAAAATCCACTCAAATTGGAAAGGTATTGCTAACAGGATGCTTTAAAAGTCTGT
GTATGAAATAGCAATGATGATGATAATACTGCATTTCATCTTGCCACAAAGGAACATTTTATAA
TCCCTAAAAGTAAACTTCAGAAATCTTTACATTTTTTCAAGTAACATCTATCTTTTGTATAATT
CACATTTGGGAACACGACTTTCAGTAATGTTCTTCCCACAAATAATCATGCTTATTTCCCTCTG
TGATTACAGCATTAAACTCTACTTTAAGTTGTATTTGAATTTTATTGTTTTGTTATTTAAGTTT
TTGTTATTTATAAAGAAAAAAACTTAAGAAGCTGTATCTGTTTCATATGCTTTTAATTTCAAGG
GGACAACAAACCCGTCTGGCTGCACTGCAGATGTCTCCTCCCCTGGTGGCTGACACCAAGTCTA
GCACACAACACTTGGCTAGCAAGTGCTGGATGGCAGACAAAAACGACAGGCTGCAGCCATGCCT
CCAATAGATGTCTCATAGTGAACGATACGAATATGTGGGAAAGATTTCACACAACGCTCATGCC
AATGAATTTGGATCATATAAGTAAAAGAAATCAAAGTATTTAGTGAGGACATATTTTTGAAAGT
AGGCATATTTAAAGTTAGCAATTTGATCATCTTTAGAAGTTTCTGCCATACAAAATATGCCAAC
TTTGAAATGTCAAGAGTAAAACCCCAAATAGAGGTTGTAGTCAGGGTACAGGGCCCTAAACACC
TTGAGGCTTCAGGTCAGGCCACAGATAACAGGCTTAAAAAACACATGAACTTACTCCATAGTTC
TGCCACCAGTGGATGCTGACAGAAATGTATATATACTTATGAAGGGAAGTGCAACATTTATTTA
AATTGTTGGTATATTAATTAATGTGATATCAACTTCATAGTGGTTGTCATTAAAGTTTCTTTAT
ATTACATACAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_071518	(Get FASTA)	NCBI Sequence Viewer
	XP_006234965	(Get FASTA)	NCBI Sequence Viewer
	XP_017447007	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAG31597	(Get FASTA)	NCBI Sequence Viewer
	CAA39892	(Get FASTA)	NCBI Sequence Viewer
	CAA65056	(Get FASTA)	NCBI Sequence Viewer
	EDL80082	(Get FASTA)	NCBI Sequence Viewer
	Q02195	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_071518 ⟸ NM_022182
- Peptide Label:	precursor
- UniProtKB:	Q02195 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MRKWILTRILPTPLYRPCFHLVCLVGTISLACNDMSPEQTATSVNCSSPERHTRSYDYMEGGDI RVRRLFCRTQWYLRIDKRGKVKGTQEMRNSYNIMEIMTVAVGIVAIKGVESEYYLAMNKQGELY AKKECNEDCNFKELILENHYNTSASAKWTHSGGEMFVALNQKGLPVKGKKTKKEQKTAHFLPMA IT hide sequence

RefSeq Acc Id:	XP_006234965 ⟸ XM_006234903
- Peptide Label:	isoform X1
- UniProtKB:	G3V775 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRKWILTRILPTPLYRSCFHLVCLVGTISLACNDMSPEQTATSVNCSSPERHTRSYDYMEGGDI RVRRLFCRTQWYLRIDKRGKVKGTQEMRNSYNIMEIRTVAVGIVAIKGVESEYYLAMNKEGKLY AKKECNEDCNFKELILENHYNTYASAKWTHSGGEMFVALNQKGLPVKGKKTKKEQKTAHFLPMA IT hide sequence

RefSeq Acc Id:	XP_017447007 ⟸ XM_017591518
- Peptide Label:	isoform X1
- UniProtKB:	G3V775 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRKWILTRILPTPLYRSCFHLVCLVGTISLACNDMSPEQTATSVNCSSPERHTRSYDYMEGGDI RVRRLFCRTQWYLRIDKRGKVKGTQEMRNSYNIMEIRTVAVGIVAIKGVESEYYLAMNKEGKLY AKKECNEDCNFKELILENHYNTYASAKWTHSGGEMFVALNQKGLPVKGKKTKKEQKTAHFLPMA IT hide sequence

RefSeq Acc Id:

ENSRNOP00000012700 ⟸ ENSRNOT00000012700

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692385

Promoter ID:

EPDNEW_R2910

Type:

initiation region

Name:

Fgf7_1

Description:

fibroblast growth factor 7

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	118,317,831 - 118,317,891	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:61805	AgrOrtholog
Ensembl Genes	ENSRNOG00000009425	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000012700	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000012700	ENTREZGENE, UniProtKB/TrEMBL
InterPro	FGF7	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Fibroblast_GF_fam	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IL1/FGF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:29348	UniProtKB/Swiss-Prot
NCBI Gene	29348	ENTREZGENE
PANTHER	PTHR11486	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR11486:SF20	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	FGF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Fgf7	PhenoGen
PRINTS	HBGFFGF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	HBGF_FGF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	FGF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF50353	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene	Rn.98842	ENTREZGENE
UniProt	FGF7_RAT	UniProtKB/Swiss-Prot
	G3V775	ENTREZGENE, UniProtKB/TrEMBL
	Q02195	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2002-06-10	Fgf7	fibroblast growth factor 7			Symbol and Name status set to approved	70586	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expressed at higher levels in prostates of older animals than in younger animals	68696
gene_expression	expressed at higher levels in prostates of older animals than in younger animals	70812
gene_expression	expressed in embryonic lungs	68696
gene_expression	expressed in embryonic lungs	70812
gene_expression	produced by stromal mesenchyme-derived cells	68696
gene_expression	produced by stromal mesenchyme-derived cells	70812
gene_process	enhances glucocorticoid stimulation of fetal alveolar epithelial type II cell maturation	68696
gene_process	enhances glucocorticoid stimulation of fetal alveolar epithelial type II cell maturation	70812
gene_process	stimulates surfactant component synthesis	68696
gene_process	stimulates surfactant component synthesis	70812
gene_regulation	regulated by androgen	68696
gene_regulation	regulated by androgen	70812

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)