Mybpc3 (myosin binding protein C3)

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Gene: Mybpc3 (myosin binding protein C3) Rattus norvegicus

Analyze

Symbol:

Mybpc3

Name:

myosin binding protein C3

RGD ID:

1305950

Description:

Predicted to enable identical protein binding activity and myosin heavy chain binding activity. Predicted to be a structural constituent of muscle. Involved in cardiac muscle contraction and regulation of striated muscle contraction. Located in striated muscle myosin thick filament. Human ortholog(s) of this gene implicated in familial hypertrophic cardiomyopathy; hypertrophic cardiomyopathy; and hypertrophic cardiomyopathy 4. Orthologous to human MYBPC3 (myosin binding protein C3); PARTICIPATES IN dilated cardiomyopathy pathway; hypertrophic cardiomyopathy pathway; INTERACTS WITH acetamide; amphetamine; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

C-protein, cardiac muscle isoform; cardiac MyBP-C; LOC295929; myosin binding protein C, cardiac; myosin-binding protein C, cardiac-type

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MYBPC3 (myosin binding protein C3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, PhylomeDB, Treefam
Mus musculus (house mouse):	Mybpc3 (myosin binding protein C, cardiac)	HGNC	Treefam, EggNOG, NCBI, OMA, HomoloGene, Inparanoid, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Mybpc3 (myosin binding protein C3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MYBPC3 (myosin binding protein C3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MYBPC3 (myosin binding protein C3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Mybpc3 (myosin binding protein C3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MYBPC3 (myosin binding protein C3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MYBPC3 (myosin binding protein C3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Mybpc3 (myosin binding protein C3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	MYBPC2 (myosin binding protein C2)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	MYBPC3 (myosin binding protein C3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Mus musculus (house mouse):	Mybpc3 (myosin binding protein C, cardiac)	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Danio rerio (zebrafish):	mybpc3 (myosin binding protein C, cardiac)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|TreeFam)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	77,095,165 - 77,113,406 (+)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	3	77,095,252 - 77,113,405 (+)	Ensembl
Rnor_6.0	3	79,940,509 - 79,958,731 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	79,940,561 - 79,958,730 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	86,649,264 - 86,667,484 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	75,478,579 - 75,496,750 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	3	75,375,715 - 75,394,374 (+)	NCBI
Celera	3	76,303,526 - 76,321,687 (+)	NCBI		Celera
Cytogenetic Map	3	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Animal Disease Models (ISO)

arrhythmogenic right ventricular dysplasia 1 (ISO)

Brugada syndrome (ISO)

cardiac arrest (ISO)

Cardiomegaly (ISO)

cardiomyopathy (ISO)

catecholaminergic polymorphic ventricular tachycardia (ISO)

catecholaminergic polymorphic ventricular tachycardia 1 (ISO)

congenital disorder of glycosylation type IIc (ISO)

dilated cardiomyopathy (ISO)

dilated cardiomyopathy 1A (ISO)

dilated cardiomyopathy 1B (ISO)

dilated cardiomyopathy 1H (ISO)

Dilated Cardiomyopathy with Left Ventricular Noncompaction (ISO)

Dyspnea (ISO)

Familial Amyloid Polyneuropathies (ISO)

familial hypertrophic cardiomyopathy (ISO)

genetic disease (ISO)

Heart Block (ISO)

Hirschsprung's disease (ISO)

hypertrophic cardiomyopathy (ISO)

hypertrophic cardiomyopathy 1 (ISO)

hypertrophic cardiomyopathy 4 (ISO)

intellectual disability (ISO)

Isolated Noncompaction of the Ventricular Myocardium (ISO)

Left Ventricular Hypertrophy (ISO)

left ventricular noncompaction (ISO)

Left Ventricular Noncompaction 1 (ISO)

Left Ventricular Noncompaction 10 (ISO)

long QT syndrome (ISO)

neuritis (ISO)

neuropathy (ISO)

Paroxysmal Atrial Fibrillation (ISO)

peripheral nervous system disease (ISO)

Sudden Cardiac Death (ISO)

Sudden Death (ISO)

Sudden Unexpected Nocturnal Death Syndrome (ISO)

Tachycardia (ISO)

transthyretin amyloidosis (ISO)

Ventricular Premature Complexes (ISO)

Wolff-Parkinson-White syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile (ISO)

4,4'-sulfonyldiphenol (ISO)

acetamide (EXP)

amphetamine (EXP)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

C60 fullerene (EXP)

calcium atom (ISO)

calcium(0) (ISO)

chlorpyrifos (ISO)

crocidolite asbestos (ISO)

decabromodiphenyl ether (EXP)

dextran sulfate (ISO)

dibutyl phthalate (EXP,ISO)

disodium selenite (ISO)

doxorubicin (ISO)

endosulfan (EXP)

folic acid (ISO)

genistein (ISO)

glycidol (EXP)

Indeno[1,2,3-cd]pyrene (ISO)

isoprenaline (ISO)

linsidomine (EXP)

methamphetamine (ISO)

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO)

N-nitrosodiethylamine (ISO)

nitrofen (EXP)

paraquat (EXP)

perfluorooctanoic acid (EXP)

phenylephrine (ISO)

piperonyl butoxide (ISO)

sulforaphane (ISO)

sunitinib (ISO)

thalidomide (ISO)

titanium dioxide (ISO)

triclosan (ISO)

triptonide (ISO)

verapamil (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cardiac muscle contraction (IEP,ISO)

cell adhesion (IEA)

heart morphogenesis (ISO)

muscle contraction (ISO)

myosin filament assembly (ISO)

regulation of heart contraction (ISO)

regulation of heart rate (ISO)

regulation of striated muscle contraction (IEP)

sarcomere organization (ISO)

ventricular cardiac muscle tissue morphogenesis (ISO)

Cellular Component

A band (ISO)

cardiac myofibril (ISO)

myofibril (ISO)

sarcomere (ISO)

striated muscle myosin thick filament (IDA,ISO)

Molecular Function

actin binding (IEA)

identical protein binding (ISO)

metal ion binding (IEA)

molecular_function (ND)

myosin binding (ISO)

myosin heavy chain binding (IBA,ISO)

protein binding (ISO)

structural constituent of muscle (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

dilated cardiomyopathy pathway (IEA)

hypertrophic cardiomyopathy pathway (IEA)

References

References - curated


1.	Brown LJ, etal., Eur Biophys J. 2002 Sep;31(5):400-8. Epub 2002 Jun 25.
2.	Carrier L, etal., Circ Res. 1997 Mar;80(3):427-34.
3.	Garcia-Castro M, etal., Int J Cardiol. 2005 Jul 20;102(3):501-7. Epub 2004 Sep 23.
4.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5.	GOA data from the GO Consortium
6.	Jaaskelainen P, etal., J Mol Med. 2002 Jul;80(7):412-22. Epub 2002 Apr 11.
7.	MGD data from the GO Consortium
8.	Niimura H, etal., N Engl J Med. 1998 Apr 30;338(18):1248-57.
9.	OMIM Disease Annotation Pipeline
10.	Peddy SB, etal., Pediatrics. 2006 May;117(5):1830-3.
11.	Pipeline to import KEGG annotations from KEGG into RGD
12.	RGD automated data pipeline
13.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14.	RGD automated import pipeline for gene-chemical interactions
15.	RGD comprehensive gene curation
16.	Van Driest SL, etal., J Am Coll Cardiol. 2004 Nov 2;44(9):1903-10.
17.	Wang P, etal., Biochem Biophys Res Commun. 2005 Apr 8;329(2):796-9.
18.	Weisberg A and Winegrad S, Proc Natl Acad Sci U S A. 1996 Aug 20;93(17):8999-9003.

Additional References at PubMed

PMID:7493025	PMID:8618961	PMID:9784245	PMID:10024460	PMID:10532952	PMID:10545522	PMID:11815426	PMID:14500336	PMID:15059932	PMID:15472117	PMID:16224063	PMID:16380103
PMID:16754800	PMID:17075052	PMID:17192269	PMID:17254601	PMID:18201573	PMID:19850579	PMID:21971072	PMID:22527638	PMID:22982234	PMID:25512492	PMID:25583989	PMID:25771144
PMID:26316108	PMID:27233767	PMID:28315668	PMID:29470978	PMID:30082313	PMID:31308242

Genomics

Comparative Map Data

Mybpc3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	77,095,165 - 77,113,406 (+)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	3	77,095,252 - 77,113,405 (+)	Ensembl
Rnor_6.0	3	79,940,509 - 79,958,731 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	79,940,561 - 79,958,730 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	86,649,264 - 86,667,484 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	75,478,579 - 75,496,750 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	3	75,375,715 - 75,394,374 (+)	NCBI
Celera	3	76,303,526 - 76,321,687 (+)	NCBI		Celera
Cytogenetic Map	3	q24	NCBI

MYBPC3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	11	47,331,406 - 47,352,702 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	11	47,331,406 - 47,352,702 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	11	47,352,957 - 47,374,253 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	47,309,533 - 47,330,829 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	11	47,309,526 - 47,330,798	NCBI
Celera	11	47,492,237 - 47,513,531 (-)	NCBI
Cytogenetic Map	11	p11.2	NCBI
HuRef	11	47,052,045 - 47,073,383 (-)	NCBI		HuRef
CHM1_1	11	47,352,197 - 47,373,500 (-)	NCBI		CHM1_1

Mybpc3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	90,948,459 - 90,966,861 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	2	90,948,489 - 90,966,861 (+)	Ensembl
GRCm38	2	91,118,114 - 91,136,516 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	91,118,144 - 91,136,516 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	90,958,301 - 90,976,673 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	2	90,919,009 - 90,937,348 (+)	NCBI			mm8
Celera	2	92,502,890 - 92,521,291 (+)	NCBI		Celera
Cytogenetic Map	2	E1	NCBI

Mybpc3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	888,589 - 901,725 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955422	888,529 - 902,074 (+)	NCBI	ChiLan1.0	ChiLan1.0

MYBPC3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	11	47,830,605 - 47,851,909 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	47,831,087 - 47,851,849 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	11	47,277,799 - 47,299,102 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

MYBPC3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	42,271,159 - 42,288,782 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	42,271,724 - 42,289,215 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	41,000,886 - 41,017,318 (+)	NCBI
ROS_Cfam_1.0	18	42,926,187 - 42,943,245 (+)	NCBI
UMICH_Zoey_3.1	18	42,412,622 - 42,429,047 (+)	NCBI
UNSW_CanFamBas_1.0	18	41,967,840 - 41,984,282 (+)	NCBI
UU_Cfam_GSD_1.0	18	42,697,140 - 42,713,582 (+)	NCBI

Mybpc3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	19,759,573 - 19,778,450 (+)	NCBI
SpeTri2.0	NW_004936562	1,871,194 - 1,890,092 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MYBPC3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	15,247,539 - 15,270,104 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	15,247,679 - 15,269,714 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	16,454,543 - 16,476,408 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MYBPC3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	17,964,581 - 17,986,351 (+)	NCBI
ChlSab1.1 Ensembl	1	17,963,706 - 17,985,758 (+)	Ensembl
Vero_WHO_p1.0	NW_023666038	115,266,096 - 115,286,419 (+)	NCBI

Mybpc3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624767	1,406,563 - 1,420,778 (+)	NCBI

Position Markers

PMC181559P1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	77,111,683 - 77,112,044 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	79,957,009 - 79,957,369	NCBI	Rnor6.0
Rnor_5.0	3	86,665,762 - 86,666,122	UniSTS	Rnor5.0
RGSC_v3.4	3	75,495,029 - 75,495,389	UniSTS	RGSC3.4
Celera	3	76,319,966 - 76,320,326	UniSTS
Cytogenetic Map	3	q24	UniSTS

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2290452	Scl56	Serum cholesterol level QTL 56	2.26		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	3	1	91609953	Rat
1358905	Hrtrt17	Heart rate QTL 17	5.9	0.000014	heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	10861912	89878372	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	29463235	118376539	Rat
61419	Cia11	Collagen induced arthritis QTL 11	5.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	3	30356773	98535386	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	31172320	163586636	Rat
1354589	Bw31	Body weight QTL 31	3.3		body mass (VT:0001259)	body weight (CMO:0000012)	3	33703347	78196190	Rat
1354604	Bw36	Body weight QTL 36	2.9		body mass (VT:0001259)	body weight (CMO:0000012)	3	33703347	104104347	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	38192233	133483320	Rat
738019	Anxrr10	Anxiety related response QTL 10	3.9		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	3	38517803	83517803	Rat
1331777	Bw24	Body weight QTL 24	3.503		body mass (VT:0001259)	body weight (CMO:0000012)	3	39454637	89115240	Rat
1331795	Rf30	Renal function QTL 30	3.708		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	3	39454637	89115240	Rat
1354597	Kidm13	Kidney mass QTL 13	2.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	3	41874578	104104347	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	41874578	155617519	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	41874578	155617519	Rat
1300178	Hrtrt4	Heart rate QTL 4	3.74		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	43827364	90905114	Rat
1581503	Cm58	Cardiac mass QTL 58	2.7	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	43827364	121056321	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	43827364	169034231	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)