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Gene: Itpka (inositol-trisphosphate 3-kinase A) Rattus norvegicus
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Symbol: Itpka
Name: inositol-trisphosphate 3-kinase A
RGD ID: 619950
Description: Exhibits Rac GTPase binding activity; calmodulin-dependent protein kinase activity; and inositol-1,4,5-trisphosphate 3-kinase activity. Involved in actin cytoskeleton organization; dendritic spine maintenance; and positive regulation of dendritic spine morphogenesis. Localizes to dendritic spine. Orthologous to human ITPKA (inositol-trisphosphate 3-kinase A); PARTICIPATES IN inositol metabolic pathway; inositol phosphate metabolic pathway; calcium/calcium-mediated signaling pathway; INTERACTS WITH (+)-schisandrin B; 1,3,5-trinitro-1,3,5-triazinane; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: inositol 1,4,5-triphosphate 3-kinase; inositol 1,4,5-trisphosphate 3-kinase A; inositol 145-triphosphate 3-kinase; insP 3-kinase A; IP3 3-kinase A; IP3K A
Orthologs:
Homo sapiens (human) : ITPKA (inositol-trisphosphate 3-kinase A)  HGNC  Alliance
Mus musculus (house mouse) : Itpka (inositol 1,4,5-trisphosphate 3-kinase A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itpka (inositol-trisphosphate 3-kinase A)
Pan paniscus (bonobo/pygmy chimpanzee) : ITPKA (inositol-trisphosphate 3-kinase A)
Canis lupus familiaris (dog) : ITPKA (inositol-trisphosphate 3-kinase A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itpka (inositol-trisphosphate 3-kinase A)
Sus scrofa (pig) : ITPKA (inositol-trisphosphate 3-kinase A)
Chlorocebus sabaeus (African green monkey) : ITPKA (inositol-trisphosphate 3-kinase A)
Heterocephalus glaber (naked mole-rat) : Itpka (inositol-trisphosphate 3-kinase A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03111,545,007 - 111,553,605 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3111,545,007 - 111,553,604 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03118,093,293 - 118,102,060 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43106,257,482 - 106,266,160 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13106,153,909 - 106,162,588 (+)NCBI
Celera3105,636,919 - 105,645,481 (+)NCBICelera
Cytogenetic Map3q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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More on Itpka
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619950
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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