ITPKA (inositol-trisphosphate 3-kinase A) - Rat Genome Database

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Gene: ITPKA (inositol-trisphosphate 3-kinase A) Sus scrofa
Analyze
Symbol: ITPKA
Name: inositol-trisphosphate 3-kinase A
RGD ID: 14120998
Description: ENCODES a protein that exhibits calmodulin-dependent protein kinase activity (ortholog); inositol-1,4,5-trisphosphate 3-kinase activity (ortholog); small GTPase binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); dendritic spine maintenance (ortholog); inositol metabolic process (ortholog); PARTICIPATES IN inositol metabolic pathway; inositol phosphate metabolic pathway; ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); genetic disease (ortholog); FOUND IN dendritic spine (ortholog); glutamatergic synapse (ortholog); postsynaptic actin cytoskeleton (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: inositol 1,4,5-trisphosphate 3-kinase A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1129,867,642 - 129,875,639 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11129,867,261 - 129,877,762 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21144,939,082 - 144,947,563 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ITPKA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1129,867,642 - 129,875,639 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11129,867,261 - 129,877,762 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21144,939,082 - 144,947,563 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ITPKA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381541,493,874 - 41,503,551 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1541,493,393 - 41,503,551 (+)EnsemblGRCh38hg38GRCh38
GRCh371541,786,072 - 41,795,749 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361539,573,414 - 39,583,039 (+)NCBINCBI36Build 36hg18NCBI36
Build 341539,573,413 - 39,583,037NCBI
Celera1518,554,082 - 18,563,706 (+)NCBICelera
Cytogenetic Map15q15.1NCBI
HuRef1518,634,270 - 18,643,970 (+)NCBIHuRef
CHM1_11541,904,654 - 41,914,323 (+)NCBICHM1_1
T2T-CHM13v2.01539,300,037 - 39,309,713 (+)NCBIT2T-CHM13v2.0
Itpka
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392119,572,818 - 119,581,734 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2119,572,818 - 119,581,744 (+)EnsemblGRCm39 Ensembl
GRCm382119,742,337 - 119,751,253 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2119,742,337 - 119,751,263 (+)EnsemblGRCm38mm10GRCm38
MGSCv372119,568,073 - 119,576,989 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362119,433,778 - 119,442,694 (+)NCBIMGSCv36mm8
Celera2120,898,643 - 120,907,740 (+)NCBICelera
Cytogenetic Map2E5NCBI
cM Map259.97NCBI
Itpka
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83127,179,841 - 127,188,405 (+)NCBIGRCr8
mRatBN7.23106,726,036 - 106,734,601 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3106,726,036 - 106,734,600 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3110,401,341 - 110,409,898 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03118,996,888 - 119,005,445 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03116,657,281 - 116,665,838 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03111,545,007 - 111,553,605 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3111,545,007 - 111,553,604 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03118,093,293 - 118,102,060 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43106,257,482 - 106,266,160 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13106,153,909 - 106,162,588 (+)NCBI
Celera3105,636,919 - 105,645,481 (+)NCBICelera
Cytogenetic Map3q35NCBI
Itpka
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554168,299,318 - 8,309,865 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554168,300,059 - 8,310,225 (+)NCBIChiLan1.0ChiLan1.0
ITPKA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21630,735,096 - 30,744,968 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11534,886,349 - 34,896,201 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01520,434,532 - 20,444,389 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11538,663,857 - 38,685,172 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1538,675,600 - 38,684,779 (+)Ensemblpanpan1.1panPan2
ITPKA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1308,532,191 - 8,541,273 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl308,532,284 - 8,541,285 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha308,591,175 - 8,600,076 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0308,666,590 - 8,675,492 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl308,666,590 - 8,675,501 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1308,587,903 - 8,596,796 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0308,695,316 - 8,704,204 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0308,827,050 - 8,835,956 (+)NCBIUU_Cfam_GSD_1.0
Itpka
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864086,992,042 - 87,000,822 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364714,840,152 - 4,848,881 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364714,840,113 - 4,848,881 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ITPKA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12641,502,417 - 41,512,131 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604899,468,986 - 99,479,279 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Itpka
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248048,655,777 - 8,664,600 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248048,655,762 - 8,664,599 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ITPKA
100 total Variants

Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000005245   ⟹   ENSSSCP00000080445
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1129,867,642 - 129,875,639 (-)Ensembl
RefSeq Acc Id: XM_021097438   ⟹   XP_020953097
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11129,867,261 - 129,877,762 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020953097 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000080445.1
  ENSSSCP00025031439.1
  ENSSSCP00050039647.1
  ENSSSCP00055038984.1
  ENSSSCP00065043993.1
  ENSSSCP00070033127.1
Reference Protein Sequences
RefSeq Acc Id: XP_020953097   ⟸   XM_021097438
- UniProtKB: A0A4X1UWK1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000080445   ⟸   ENSSSCT00000005245


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000004746 Ensembl, UniProtKB/TrEMBL
  ENSSSCG00025053062 UniProtKB/TrEMBL
  ENSSSCG00050067478 UniProtKB/TrEMBL
  ENSSSCG00055024772 UniProtKB/TrEMBL
  ENSSSCG00065072840 UniProtKB/TrEMBL
  ENSSSCG00070019942 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000005245.5 UniProtKB/TrEMBL
  ENSSSCT00025072567.1 UniProtKB/TrEMBL
  ENSSSCT00050092032.1 UniProtKB/TrEMBL
  ENSSSCT00055048837.1 UniProtKB/TrEMBL
  ENSSSCT00065100147.1 UniProtKB/TrEMBL
  ENSSSCT00070039551.1 UniProtKB/TrEMBL
Gene3D-CATH Inositol polyphosphate kinase UniProtKB/TrEMBL
InterPro IPK UniProtKB/TrEMBL
  IPK_sf UniProtKB/TrEMBL
NCBI Gene ITPKA ENTREZGENE
PANTHER INOSITOL POLYPHOSPHATE KINASE UniProtKB/TrEMBL
  INOSITOL-TRISPHOSPHATE 3-KINASE A UniProtKB/TrEMBL
Pfam IPK UniProtKB/TrEMBL
Superfamily-SCOP SAICAR synthase-like UniProtKB/TrEMBL
UniProt A0A4X1UWK1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FM71_PIG UniProtKB/TrEMBL