Ift70a1 (intraflagellar transport 70A1) - Rat Genome Database

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Gene: Ift70a1 (intraflagellar transport 70A1) Rattus norvegicus
Analyze
Symbol: Ift70a1 (Ensembl: Ttc30a)
Name: intraflagellar transport 70A1 (Ensembl:tetratricopeptide repeat domain 30A)
RGD ID: 2318157
Description: Predicted to enable intraciliary transport particle B binding activity. Predicted to be involved in intraciliary transport. Predicted to be located in centrosome and cilium. Predicted to be part of intraciliary transport particle B; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC100362431; tetratricopeptide repeat domain 30A; tetratricopeptide repeat domain 30A1; tetratricopeptide repeat domain 30B; Ttc30a; Ttc30a1
RGD Orthologs
Mouse
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8381,309,158 - 81,312,612 (-)NCBIGRCr8
mRatBN7.2360,901,896 - 60,905,350 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl360,901,896 - 60,905,350 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx364,275,387 - 64,278,841 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0372,859,020 - 72,862,474 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0370,626,381 - 70,629,835 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0362,803,635 - 62,810,291 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0369,354,544 - 69,354,889 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0369,350,554 - 69,352,213 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4358,645,228 - 58,651,177 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera360,401,611 - 60,405,065 (-)NCBICelera
Cytogenetic Map3q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15632090  


Genomics

Comparative Map Data
Ift70a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8381,309,158 - 81,312,612 (-)NCBIGRCr8
mRatBN7.2360,901,896 - 60,905,350 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl360,901,896 - 60,905,350 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx364,275,387 - 64,278,841 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0372,859,020 - 72,862,474 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0370,626,381 - 70,629,835 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0362,803,635 - 62,810,291 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0369,354,544 - 69,354,889 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0369,350,554 - 69,352,213 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4358,645,228 - 58,651,177 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera360,401,611 - 60,405,065 (-)NCBICelera
Cytogenetic Map3q23NCBI
Ift70a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39275,809,450 - 75,812,311 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl275,808,591 - 75,812,311 (-)EnsemblGRCm39 Ensembl
GRCm38275,979,106 - 75,981,967 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl275,978,247 - 75,981,967 (-)EnsemblGRCm38mm10GRCm38
MGSCv37275,817,163 - 75,820,024 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36275,779,086 - 75,782,608 (-)NCBIMGSCv36mm8
Celera277,640,924 - 77,643,785 (-)NCBICelera
Cytogenetic Map2C3NCBI
cM Map244.8NCBI

Variants

.
Variants in Ift70a1
15 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303593Gluco46Glucose level QTL 463blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)32846857173468571Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
631647Bp122Blood pressure QTL 1226.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)33068464275684642Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)31695470861954708Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)33851780383517803Rat
9590286Uminl1Urine mineral level QTL 13.50.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)32824968773249687Rat
8694196Abfw2Abdominal fat weight QTL 216.580.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)32824968773249687Rat
8694386Bw159Body weight QTL 1594.520.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)32824968773249687Rat
8552950Pigfal12Plasma insulin-like growth factor 1 level QTL 127.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)32824968773249687Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)33945463789115240Rat
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)34382736490905114Rat
1300169Bp177Blood pressure QTL 1772.96arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)33370334761017857Rat
1354590Despr11Despair related QTL 110.000031locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)32846857173468571Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)341874578104104347Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1582249Bw77Body weight QTL 773.20.0025epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)35318459364655484Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
61356Bp37Blood pressure QTL 373blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)33068464275684642Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)35318469289878207Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)33035677398535386Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31500542276927699Rat
2302055Pia30Pristane induced arthritis QTL 303.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)32793691972936919Rat
2301400Cm68Cardiac mass QTL 680.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)33142640370668733Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
10450804Scl70Serum cholesterol level QTL 704.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)33370334778196190Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)33945463789115240Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
10450794Scl69Serum cholesterol level QTL 696.30.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
11565451Bw177Body weight QTL 1770.002body mass (VT:0001259)body weight (CMO:0000012)33142640370668733Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)35378111291609953Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)35378111291609953Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35378111291609953Rat
11565452Kidm57Kidney mass QTL 570.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)33142640370668733Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
9590136Scort3Serum corticosterone level QTL 323.370.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)32824968773249687Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
12879867Cm95Cardiac mass QTL 950.047heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)33142640370668733Rat
12879868Am6Aortic mass QTL 60.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)33142640370668733Rat
2302276Bw82Body weight QTL 824.32body mass (VT:0001259)body weight (CMO:0000012)33945463762951183Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
12879866Cm94Cardiac mass QTL 940.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)33142640370668733Rat

Markers in Region
D3Rat179  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2360,907,147 - 60,907,273 (+)MAPPERmRatBN7.2
Rnor_6.0362,812,090 - 62,812,215NCBIRnor6.0
Rnor_5.0369,356,688 - 69,356,813UniSTSRnor5.0
RGSC_v3.4358,653,182 - 58,653,308RGDRGSC3.4
RGSC_v3.4358,653,183 - 58,653,308UniSTSRGSC3.4
RGSC_v3.1358,549,407 - 58,549,722RGD
Celera360,406,863 - 60,406,986UniSTS
SHRSP x BN Map338.3398UniSTS
SHRSP x BN Map338.3398RGD
RH133128  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2360,902,761 - 60,902,971 (+)MAPPERmRatBN7.2
Rnor_6.0362,804,501 - 62,804,710NCBIRnor6.0
Rnor_5.0369,351,420 - 69,351,629UniSTSRnor5.0
RGSC_v3.4358,648,797 - 58,649,006UniSTSRGSC3.4
Celera360,402,477 - 60,402,686UniSTS
Cytogenetic Map3q23UniSTS
RH138121  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2360,899,226 - 60,899,375 (+)MAPPERmRatBN7.2
Rnor_6.0362,800,966 - 62,801,114NCBIRnor6.0
Rnor_5.0369,347,885 - 69,348,033UniSTSRnor5.0
RGSC_v3.4358,645,262 - 58,645,410UniSTSRGSC3.4
Celera360,398,942 - 60,399,090UniSTS
Cytogenetic Map3q23UniSTS


Expression


Sequence


RefSeq Acc Id: ENSRNOT00000100897   ⟹   ENSRNOP00000081765
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl360,901,896 - 60,905,350 (-)Ensembl
RefSeq Acc Id: NM_001271494   ⟹   NP_001258423
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8381,309,158 - 81,312,612 (-)NCBI
mRatBN7.2360,901,896 - 60,905,350 (-)NCBI
Rnor_6.0362,803,635 - 62,810,291 (-)NCBI
Rnor_5.0369,350,554 - 69,352,213 (-)NCBI
Rnor_5.0369,354,544 - 69,354,889 (-)NCBI
Celera360,401,611 - 60,405,065 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001258423 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL79217 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000045862.2
  ENSRNOP00000081765
  ENSRNOP00000081765.1
RefSeq Acc Id: NP_001258423   ⟸   NM_001271494
- UniProtKB: A0A8I5ZT76 (UniProtKB/TrEMBL),   A6HMG6 (UniProtKB/TrEMBL),   A0A0H2UHX9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000081765   ⟸   ENSRNOT00000100897

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-49294 BioCyc
Ensembl Genes ENSRNOG00000059460 UniProtKB/TrEMBL
  ENSRNOG00000069321 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000050515.3 UniProtKB/TrEMBL
  ENSRNOT00000100897 ENTREZGENE
  ENSRNOT00000100897.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
InterPro TPR-like_helical_dom_sf UniProtKB/TrEMBL
  TPR_repeat UniProtKB/TrEMBL
  TT30 UniProtKB/TrEMBL
KEGG Report rno:100362431 UniProtKB/TrEMBL
NCBI Gene 100362431 ENTREZGENE
PANTHER PTHR20931 UniProtKB/TrEMBL
  TETRATRICOPEPTIDE REPEAT PROTEIN 30B UniProtKB/TrEMBL
Pfam TPR_16 UniProtKB/TrEMBL
PhenoGen Ift70a1 PhenoGen
RatGTEx ENSRNOG00000059460 RatGTEx
  ENSRNOG00000069321 RatGTEx
SMART TPR UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/TrEMBL
UniProt A0A0H2UHX9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZT76 ENTREZGENE, UniProtKB/TrEMBL
  A6HMG6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-03-16 Ift70a1  intraflagellar transport 70A1  Ttc30a1  tetratricopeptide repeat domain 30A1  Name and Symbol changed 629549 APPROVED
2023-02-27 Ttc30a1  tetratricopeptide repeat domain 30A1  Ttc30a  tetratricopeptide repeat domain 30A  Name and Symbol changed 629549 APPROVED
2014-07-18 Ttc30a  tetratricopeptide repeat domain 30A  LOC100362431  tetratricopeptide repeat domain 30B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-05 LOC100362431  tetratricopeptide repeat domain 30B      Symbol and Name status set to provisional 70820 PROVISIONAL