Bmf (Bcl2 modifying factor) - Rat Genome Database

Name: Bmf
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Bmf (Bcl2 modifying factor) Rattus norvegicus

Analyze

Symbol:

Bmf

Name:

Bcl2 modifying factor

RGD ID:

628658

Description:

Predicted to be involved in several processes, including negative regulation of autophagic cell death; negative regulation of autophagy; and positive regulation of cellular component organization. Predicted to act upstream of or within anoikis; negative regulation of apoptotic signaling pathway; and positive regulation of apoptotic signaling pathway. Located in acrosomal vesicle. Orthologous to human BMF (Bcl2 modifying factor); PARTICIPATES IN intrinsic apoptotic pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Bcl-2 modifying factor; bcl-2-modifying factor; Bmf-pending

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	BMF (Bcl2 modifying factor)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Bmf (BCL2 modifying factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Bmf (Bcl2 modifying factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	BMF (Bcl2 modifying factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	BMF (Bcl2 modifying factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Bmf (Bcl2 modifying factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	BMF (Bcl2 modifying factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	BMF (Bcl2 modifying factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Bmf (Bcl2 modifying factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	ZNF521 (zinc finger protein 521)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	BMF (Bcl2 modifying factor)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Bmf (BCL2 modifying factor)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	bmf1 (BCL2 modifying factor 1)	Alliance	DIOPT (Hieranoid\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	bmf2 (BCL2 modifying factor 2)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	bmf	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	105,499,534 - 105,520,159 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	105,499,538 - 105,520,145 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	109,173,179 - 109,193,801 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	3	117,768,734 - 117,789,356 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	3	115,429,111 - 115,449,729 (-)	NCBI	Rnor_WKY
Rnor_6.0	3	110,303,515 - 110,324,125 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	110,306,067 - 110,324,084 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	116,849,170 - 116,869,775 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	104,966,652 - 104,984,752 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	104,863,079 - 104,881,180 (-)	NCBI
Celera	3	104,419,059 - 104,437,108 (-)	NCBI		Celera
Cytogenetic Map	3	q35	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

B-Cell Chronic Lymphocytic Leukemia (ISO)

Bloom syndrome (ISO)

colorectal cancer (ISO)

Experimental Liver Cirrhosis (ISO)

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(-)-alpha-phellandrene (ISO)

(1->4)-beta-D-glucan (ISO)

1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane (ISO)

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (ISO)

1H-pyrazole (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

3,3',5,5'-tetrabromobisphenol A (ISO)

3-methylcholanthrene (ISO)

4,4'-diaminodiphenylmethane (EXP)

4,4'-sulfonyldiphenol (ISO)

4-amino-2,6-dinitrotoluene (EXP)

4-aminopyridine (EXP)

5-aza-2'-deoxycytidine (ISO)

5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole (EXP)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acetylsalicylic acid (ISO)

adefovir pivoxil (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-phellandrene (ISO)

amiodarone (EXP)

ammonium chloride (EXP)

amphetamine (EXP)

antimycin A (ISO)

Aroclor 1254 (ISO)

arsenous acid (ISO)

azoxystrobin (ISO)

benzbromarone (EXP)

benzo[a]pyrene (ISO)

Benzo[k]fluoranthene (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP,ISO)

bromobenzene (EXP)

cadmium dichloride (ISO)

carbon nanotube (ISO)

chloroacetaldehyde (ISO)

chlorpyrifos (ISO)

cidofovir anhydrous (ISO)

ciguatoxin CTX1B (ISO)

cisplatin (ISO)

clofibrate (EXP,ISO)

copper(II) sulfate (ISO)

coumestrol (ISO)

Cuprizon (EXP)

cyclosporin A (EXP,ISO)

cypermethrin (ISO)

DDT (EXP)

deguelin (ISO)

depsipeptide (ISO)

dexamethasone (ISO)

diarsenic trioxide (ISO)

diazinon (EXP)

dichloroacetic acid (ISO)

diethyl maleate (EXP)

diethylstilbestrol (ISO)

dioxygen (ISO)

endosulfan (EXP)

Enterolactone (ISO)

epoxiconazole (ISO)

estriol (ISO)

fenofibrate (EXP,ISO)

fenpyroximate (ISO)

furan (EXP,ISO)

genistein (ISO)

gentamycin (EXP)

inulin (ISO)

isoprenaline (EXP)

L-ethionine (EXP)

leflunomide (ISO)

lidocaine (EXP)

lipopolysaccharide (ISO)

manganese(II) chloride (EXP)

metformin (EXP)

N-nitrosodiethylamine (ISO)

nickel dichloride (EXP)

O-methyleugenol (ISO)

omeprazole (EXP)

ozone (ISO)

p-menthan-3-ol (ISO)

panobinostat (ISO)

paracetamol (EXP)

paraquat (EXP)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP)

phenobarbital (ISO)

picoxystrobin (ISO)

pirinixic acid (EXP,ISO)

potassium bromate (ISO)

potassium dichromate (ISO)

progesterone (ISO)

propiconazole (ISO)

propionic acid (ISO)

pyrazinecarboxamide (EXP)

resveratrol (ISO)

rotenone (EXP,ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

Se-methyl-L-selenocysteine (ISO)

Se-methylselenocysteine (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenate (ISO)

sodium dichromate (EXP)

sulforaphane (ISO)

sunitinib (ISO)

tebufenpyrad (ISO)

tetrachloromethane (EXP)

tetraphene (ISO)

thapsigargin (ISO)

thifluzamide (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

tributylstannane (ISO)

trichloroethene (EXP,ISO)

trichostatin A (ISO)

Triptolide (ISO)

triptonide (ISO)

tris(2-butoxyethyl) phosphate (ISO)

troglitazone (ISO)

trovafloxacin (ISO)

urethane (ISO)

valdecoxib (EXP)

valproic acid (ISO)

vinclozolin (EXP)

vorinostat (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

anoikis (IEA,ISO)

apoptotic process (IEA)

biological_process (ND)

cellular response to starvation (ISO)

cellular response to UV (IEA,ISO)

negative regulation of apoptotic signaling pathway (ISO)

negative regulation of autophagic cell death (ISO)

negative regulation of autophagy (IBA,IEA,ISO)

positive regulation of apoptotic process (IEA,ISO)

positive regulation of apoptotic signaling pathway (ISO)

positive regulation of protein-containing complex assembly (ISO)

positive regulation of release of cytochrome c from mitochondria (ISO)

Cellular Component

acrosomal vesicle (IDA)

actin cytoskeleton (ISO)

cytoplasm (ISO)

myosin complex (IBA,ISO)

Molecular Function

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

intrinsic apoptotic pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Bcl-2-related protein family gene expression during oligodendroglial differentiation.	Itoh T, etal., J Neurochem 2003 Jun;85(6):1500-12.
3.	BH3-only proteins in apoptosis and beyond: an overview.	Lomonosova E and Chinnadurai G, Oncogene. 2008 Dec;27 Suppl 1:S2-19.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	GOA pipeline	RGD automated data pipeline
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	Comprehensive gene review and curation	RGD comprehensive gene curation
8.	Testicular expression and distribution of the rat bcl2 modifying factor in response to reduced intratesticular testosterone.	Show MD, etal., Biol Reprod. 2004 Apr;70(4):1153-61. Epub 2003 Dec 10.

Additional References at PubMed

PMID:11546872	PMID:18222916	PMID:19671867	PMID:20841353	PMID:21041309	PMID:23629966	PMID:27539959	PMID:31200256	PMID:36315357

Genomics

Comparative Map Data

Bmf
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	105,499,534 - 105,520,159 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	105,499,538 - 105,520,145 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	109,173,179 - 109,193,801 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	3	117,768,734 - 117,789,356 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	3	115,429,111 - 115,449,729 (-)	NCBI	Rnor_WKY
Rnor_6.0	3	110,303,515 - 110,324,125 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	110,306,067 - 110,324,084 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	116,849,170 - 116,869,775 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	104,966,652 - 104,984,752 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	104,863,079 - 104,881,180 (-)	NCBI
Celera	3	104,419,059 - 104,437,108 (-)	NCBI		Celera
Cytogenetic Map	3	q35	NCBI

BMF
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	40,087,890 - 40,108,879 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	15	40,087,890 - 40,108,892 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	40,380,091 - 40,401,080 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	38,167,383 - 38,188,367 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	15	38,167,385 - 38,185,931	NCBI
Celera	15	17,145,999 - 17,167,002 (-)	NCBI		Celera
Cytogenetic Map	15	q15.1	NCBI
HuRef	15	17,223,445 - 17,244,440 (-)	NCBI		HuRef
CHM1_1	15	40,499,972 - 40,520,967 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	15	37,894,726 - 37,915,713 (-)	NCBI		T2T-CHM13v2.0

Bmf
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	118,359,238 - 118,385,280 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	118,359,238 - 118,380,168 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	118,528,757 - 118,549,686 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	118,528,757 - 118,549,687 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	118,354,493 - 118,375,414 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	118,220,198 - 118,241,119 (-)	NCBI		MGSCv36	mm8
Celera	2	119,683,712 - 119,704,619 (-)	NCBI		Celera
Cytogenetic Map	2	E5	NCBI

Bmf
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955416	7,052,290 - 7,068,910 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955416	7,048,654 - 7,068,917 (-)	NCBI	ChiLan1.0	ChiLan1.0

BMF
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	15	33,477,368 - 33,498,321 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	19,026,053 - 19,047,008 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	37,281,655 - 37,302,365 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	37,281,655 - 37,302,075 (-)	Ensembl	panpan1.1		panPan2

BMF
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	30	7,301,000 - 7,321,949 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	30	7,274,174 - 7,322,034 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	30	7,355,731 - 7,376,675 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	30	7,429,431 - 7,450,406 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	30	7,402,587 - 7,450,406 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	30	7,351,934 - 7,372,873 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	30	7,458,286 - 7,479,257 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	30	7,586,431 - 7,607,394 (-)	NCBI		UU_Cfam_GSD_1.0

Bmf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	85,725,364 - 85,746,902 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936471	3,577,221 - 3,594,981 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936471	3,573,437 - 3,594,438 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

BMF
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	131,178,315 - 131,200,393 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	131,178,021 - 131,199,668 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

BMF
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	42,893,997 - 42,915,062 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	26	42,894,460 - 42,915,062 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	98,040,714 - 98,061,923 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Bmf
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624804	7,423,547 - 7,440,014 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624804	7,420,003 - 7,440,012 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Bmf
59 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	212
Count of miRNA genes:	133
Interacting mature miRNAs:	160
Transcripts:	ENSRNOT00000010381
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	29463235	118376539	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	31172320	163586636	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	38192233	133483320	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	41874578	155617519	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	41874578	155617519	Rat
1581503	Cm58	Cardiac mass QTL 58	2.7	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	43827364	121056321	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	43827364	169034231	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	47233211	147415807	Rat
1358186	Ept2	Estrogen-induced pituitary tumorigenesis QTL 2	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	47233430	110362260	Rat
2292613	Ept16	Estrogen-induced pituitary tumorigenesis QTL 16	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	47233430	110362260	Rat
631665	Bw8	Body weight QTL 8	5.5		body mass (VT:0001259)	body weight (CMO:0000012)	3	50437042	119183768	Rat
724523	Tsu1	Thymus enlargement suppressive QTL 1	3.84		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	3	50437504	115638231	Rat
1582218	Bw74	Body weight QTL 74	3.9	0.0021	body mass (VT:0001259)	body weight (CMO:0000012)	3	53184593	115665732	Rat
1582238	Bw68	Body weight QTL 68	3.2	0.0064	body mass (VT:0001259)	body weight (CMO:0000012)	3	53184593	115665732	Rat
1582239	Epfw1	Epididymal fat weight QTL 1	4.5	0.0006	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	3	53184593	115665732	Rat
1581568	Rf53	Renal function QTL 53			urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	3	56395968	161299569	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	59242096	157323038	Rat
1300111	Rf12	Renal function QTL 12	3.78		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	61017749	121056321	Rat
1582210	Bw71	Body weight QTL 71	3.3	0.0012	body mass (VT:0001259)	body weight (CMO:0000012)	3	64655305	115665732	Rat
1582221	Kidm30	Kidney mass QTL 30	3.5	0.0008	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	3	64655305	115665732	Rat
12879848	Bw181	Body weght QTL 181		0.015	body mass (VT:0001259)	body weight (CMO:0000012)	3	70348525	121056321	Rat
2301414	Kidm37	Kidney mass QTL 37		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	70653097	121056321	Rat
1600376	Arunc5	Aerobic running capacity QTL 5		0.21	exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	3	73376539	118376539	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	78196190	146592722	Rat
2302273	Gluco35	Glucose level QTL 35	5.3	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	80800231	114297550	Rat
631649	Bp123	Blood pressure QTL 123	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	89772419	134772419	Rat
8694437	Bw167	Body weight QTL 167	22.46	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	3	91797474	136797474	Rat
631841	Niddm39	Non-insulin dependent diabetes mellitus QTL 39	3.36		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	94856903	159898684	Rat
724532	Cm17	Cardiac mass QTL 17	2		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	3	95735366	140735366	Rat
1582219	Bw63	Body weight QTL 63	3.8	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	3	96127817	115665732	Rat
1354611	Despr2	Despair related QTL 2	3.03	0.0028	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	3	97084464	142084464	Rat
2293087	Iddm27	Insulin dependent diabetes mellitus QTL 27	2.68		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	97551417	147415807	Rat
2312659	Slep7	Serum leptin concentration QTL 7		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	3	98535255	168026850	Rat
2312670	Bw94	Body weight QTL 94		0.01	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	3	98535255	168026850	Rat
2312673	Scl63	Serum cholesterol level QTL 63		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	98535255	168026850	Rat
2302373	Gluco39	Glucose level QTL 39	5.01		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	3	98535386	161695835	Rat
1582216	Bw65	Body weight QTL 65	6.3		body mass (VT:0001259)	body weight (CMO:0000012)	3	102200529	115665732	Rat

Markers in Region

D15S214

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	105,519,233 - 105,519,547 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	110,323,212 - 110,323,527	NCBI	Rnor6.0
Rnor_5.0	3	116,868,867 - 116,869,182	UniSTS	Rnor5.0
RGSC_v3.4	3	104,983,880 - 104,984,195	UniSTS	RGSC3.4
Celera	3	104,436,198 - 104,436,551	UniSTS
Cytogenetic Map	3	q35	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium		12	31	19	19	19			16	34	33	11
Low	3	31	26	22		22	8	11	58	1	6		8
Below cutoff											2

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001401791	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_139258	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006234723	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006234724	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008762079	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039104249	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005501773	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF506761	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000118	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000010381 ⟹ ENSRNOP00000010381

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	105,499,538 - 105,520,145 (-)	Ensembl
Rnor_6.0 Ensembl	3	110,306,067 - 110,324,084 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000105313 ⟹ ENSRNOP00000096398

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	105,499,538 - 105,517,800 (-)	Ensembl

RefSeq Acc Id:

NM_139258 ⟹ NP_640351

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	105,502,085 - 105,520,104 (-)	NCBI
Rnor_6.0	3	110,306,067 - 110,324,084 (-)	NCBI
Rnor_5.0	3	116,849,170 - 116,869,775 (-)	NCBI
RGSC_v3.4	3	104,966,652 - 104,984,752 (-)	RGD
Celera	3	104,419,059 - 104,437,108 (-)	RGD

Sequence:

show sequence

ATTTTGGAAACAATACCGCGCGGTGCGCGGTGGCCTCCTCCCGCGCCAGCTCACGCCCACAGCA
GTCGCTGCCCGAGCCCGCGCCACCACCTCCCACCGCAGCCCGCTGGAGTTTGTCCCCTTCTTCC
CAATCGAGTGTGGGCGCCAAGTCCCCCGAGTGTTCGTCACCCTGGACCCTGGCGCAGAGCCCTG
GCATCACGACTCGGAGGCTGAGACGCTGTCCTGGAGTCACCCAGGAGACATGGAGCCACCTCAG
TGTGTGGAGGAACTAGAAGATGATGTGTTCCAGCCAGAGGATGGGGAGCCAGGGACACAGCCTG
GGAGCTTGCTCTCTGCTGACCTGTTTGCCCAGAGCCAGCTGGATTGTCCCCTCAGTCGGCTTCA
GCTCTTCCCGCTTACCCACTGCTGTGGTCCTGGGCTCCGGCCTGTAAGCCAGGAAGACAAGGCC
ACCCAGACCCTCAGCCCAGCCTCCCCAAGCCAGGGTGTCATGCTGCCTTGTGGGGTGACAGAGG
AACCCCAGAGACTCTTTTACGGCAACGCTGGCTACAGGCTTCCTCTCCCTGCCAGTTTCCCCGC
AGGCTCAGCCCTTGGGGAGCAGCCCCCTGAAGGACAGTTCCTTCAGCACCGAGCAGAGGTACAG
ATCGCCAGAAAGCTTCAGTGCATTGCAGACCAGTTCCATCGGCTTCATATGCAACAACACCAGC
AGAACCGAGACCGAGCATGGCGGCAGGTCTTCCTCTTCCTTCAAAACCTGGCCTTGAACAGACG
AGAAAACAGGGAAGGGGTGGGTCCCTGGTGAGACTGGGCTGCTCTTGTCGGATAGATCGCCCGG
AATGCAGTCTGGAACAGACATTCTGGGAGGACAGATACTGTCTTGTCAAGTTTTGTCATTCTGA
ATTTTCTTTCCATGTGTACATATTACATACCCCAGTGGGATCTTTTTTCCCCGTTCAGAACGTC
TCCTGGGGATGGGGGCCTTTGTCAAACACTGTTGAAGGAGAGGCAGCTGTGTCTGCTGGTTGAG
TTCCTAAGGCTCTGAAGATGACCAACTGGCGATGTTCTCCAGGAAGTGAACTGAGGCTTGCTAC
TGGAGCTGGTTAAGTCAGGTGAGGCTCCCAGTACCATCAGACGTGCCAGCCTTGCCTCGTGCGT
GCCTGACGGAATCATGGCTTTAACCCACCAGGATCTTGCCTGGGAGCTTTCTGGCTAAGAACAG
CTGTGCCTCGGCTAGCTAGCTTTACATCTGGGTTCCCACTTGGCACAGCCAGTGCCCACCGCAT
GGGCTCAGGGATTCTTACTCAGTCGCTGTCAACCTCCAGAAGACCTCAGGGAGGGTTGGACTTC
ACCAAGAACCCCTCAAAGGTGCCACAAAAATGAATCAAGCTTGATAGGCTTCAAGTCTGACTCG
GTCCTACATGGAGACCCTTGGATTGGTCCCAAGGGTGCAAACTGCTGCCACCTTTGCTGCCTGG
GTGTCAACCACGTGGGAGCCAAGTAGTCAGTTACCACCATGCTGTTGTACCAGCGGCCCGTGAC
TTTGTCAGCTTTGTTTTCAAAGACTCTGCCAATGACTGGACTGGATTGGACTGCGTCCAGATCA
GCAGCAGCGCTCCAAGATGCGGTGGGCTTGCTGGGGGCGTGGGAGCCAAGCAGCCATCCCACTG
ATAAACCGGTCCCAGGGGAATCCTAGACCTCTTGGTTTCCTTGGAAACGTGTACCTCCTCCCCC
TCACCCCAATTCCTTTTCTGTACCTAGTGGGATACGGGAAGAAGCGAGGACAGTGGCTTTGTCA
GCTGGAAAGCGACTTTGGAAGGAGCAGACGTGACTATGGGACCTGCCGACTCGAGAGCTGACAC
ATCTCGAATCTTCTTCCTTCAGCTTTCAGCTAGGCCAGAAGGGAGAGTTCTAGAAGGATCTCAG
CTGCCTCCGACCTTCTTCCTTCTCTCCCTGACGCAGCGCTCAGGGAGGCAACGATAAGCAGCTG
ATCTTAGAAATCAAGTCCTAACTTTTATGTATGTAAGGAAAGACATTGGTGCTAAAATGAAGGG
GAGCCAAGGCTCAAATAAAAGATGGCTTCCCTGAGC

hide sequence

RefSeq Acc Id:

XM_006234724 ⟹ XP_006234786

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	105,503,224 - 105,520,159 (-)	NCBI
Rnor_6.0	3	110,307,259 - 110,324,125 (-)	NCBI
Rnor_5.0	3	116,849,170 - 116,869,775 (-)	NCBI

Sequence:

show sequence

GGGGCCTCATCAGCTGTTTGCGGGATGCCCGGAGCGGGCGTATTTTGGAAACAATACCGCGCGG
TGCGCGGTGGCCTCCTCCCGCGCCAGCTCACGCCCACAGCAGTCGCTGCCCGAGCCCGCGCCAC
CACCTCCCACCGCAGCCCGCTGGAGTTTGTCCCCTTCTTCCCAATCGAGTGTGGGCGCCAAGTC
CCCCGAGTGTTCGTCACCCTGGACCCTGGCGCAGAGCCCTGGCATCACGACTCGGAGGCTGAGA
CGCTGTCCTGGAGTCACCCAGGAGACATGGAGCCACCTCAGTGTGTGGAGGAACTAGAAGATGA
TGTGTTCCAGCCAGAGGATGGGGAGCCAGGGACACAGCCTGGGAGCTTGCTCTCTGCTGACCTG
TTTGCCCAGAGCCAGCTGGATTGTCCCCTCAGTCGGCTTCAGCTCTTCCCGCTTACCCACTGCT
GTGGTCCTGGGCTCCGGCCTGTAAGCCAGGAAGACAAGGCCACCCAGACCCTCAGCCCAGCCTC
CCCAAGCCAGGGTGTCATGCTGCCTTGTGGGGTGACAGAGGAACCCCAGAGACTCTTTTACGGC
AACGCTGGCTACAGGCTTCCTCTCCCTGCCAGTTTCCCCGCAGGCTCAGCCCTTGGGGAGCAGC
CCCCTGAAGGACAGTTCCTTCAGCACCGAGCAGAGCACCAGCAGAACCGAGACCGAGCATGGCG
GCAGGTCTTCCTCTTCCTTCAAAACCTGGCCTTGAACAGACGAGAAAACAGGGAAGGGGTGGGT
CCCTGGTGAGACTGGGCTGCTCTTGTCGGATAGATCGCCCGGAATGCAGTCTGGAACAGACATT
CTGGGAGGACAGATACTGTCTTGTCAAGTTTTGTCATT

hide sequence

RefSeq Acc Id:

XM_008762079 ⟹ XP_008760301

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	105,499,534 - 105,520,159 (-)	NCBI
Rnor_6.0	3	110,303,515 - 110,324,122 (-)	NCBI

Sequence:

show sequence

GCCTCATCAGCTGTTTGCGGGATGCCCGGAGCGGGCGTATTTTGGAAACAATACCGCGCGGTGC
GCGGTGGCCTCCTCCCGCGCCAGCTCACGCCCACAGCAGTCGCTGCCCGAGCCCGCGCCACCAC
CTCCCACCGCAGCCCGCTGGAGTTTGTCCCCTTCTTCCCAATCGAGTGTGGGCGCCAAGTCCCC
CGAGTGTTCGTCACCCTGGACCCTGGCGCAGAGCCCTGGCATCACGACTCGGAGGCTGAGACGC
TGTCCTGGAGTCACCCAGGAGACATGGAGCCACCTCAGTGTGTGGAGGAACTAGAAGATGATGT
GTTCCAGCCAGAGGATGGGGAGCCAGGGACACAGCCTGGGAGCTTGCTCTCTGCTGACCTGTTT
GCCCAGAGCCAGCTGGATTGTCCCCTCAGTCGGCTTCAGCTCTTCCCGCTTACCCACTGCTGTG
GTCCTGGGCTCCGGCCTGTAAGCCAGGAAGACAAGGCCACCCAGACCCTCAGCCCAGCCTCCCC
AAGCCAGGGTGTCATGCTGCCTTGTGGGGTGACAGAGGAACCCCAGAGACTCTTTTACGCACCA
GCAGAACCGAGACCGAGCATGGCGGCAGGTCTTCCTCTTCCTTCAAAACCTGGCCTTGAACAGA
CGAGAAAACAGGGAAGGGGTGGGTCCCTGGTGAGACTGGGCTGCTCTTGTCGGATAGATCGCCC
GGAATGCAGTCTGGAACAGACATTCTGGGAGGACAGATACTGTCTTGTCAAGTTTTGTCATTCT
GAATTTTCTTTCCATGTGTACATATTACATACCCCAGTGGGATCTTTTTTCCCCGTTCAGAACG
TCTCCTGGGGATGGGGGCCTTTGTCAAACACTGTTGAAGGAGAGGCAGCTGTGTCTGCTGGTTG
AGTTCCTAAGGCTCTGAAGATGACCAACTGGCGATGTTCTCCAGGAAGTGAACTGAGGCTTGCT
ACTGGAGCTGGTTAAGTCAGGTGAGGCTCCCAGTACCATCAGACGTGCCAGCCTTGCCTCGTGC
GTGCCTGACGGAATCATGGCTTTAACCCACCAGGATCTTGCCTGGGAGCTTTCTGGCTAAGAAC
AGCTGTGCCTCGGCTAGCTAGCTTTACATCTGGGTTCCCACTTGGCACAGCCAGTGCCCACCGC
ATGGGCTCAGGGATTCTTACTCAGTCGCTGTCAACCTCCAGAAGACCTCAGGGAGGGTTGGACT
TCACCAAGAACCCCTCAAAGGTGCCACAAAAATGAATCAAGCTTGATAGGCTTCAAGTCTGACT
CGGTCCTACATGGAGACCCTTGGATTGGTCCCAAGGGTGCAAACTGCTGCCACCTTTGCTGCCT
GGGTGTCAACCACGTGGGAGCCAAGTAGTCAGTTACCACCATGCTGTTGTACCAGCGGCCCGTG
ACTTTGTCAGCTTTGTTTTCAAAGACTCTGCCAATGACTGGACTGGATTGGACTGCGTCCAGAT
CAGCAGCAGCGCTCCAAGATGCGGTGGGCTTGCTGGGGGCGTGGGAGCCAAGCAGCCATCCCAC
TGATAAACCGGTCCCAGGGGAATCCTAGACCTCTTGGTTTCCTTGGAAACGTGTACCTCCTCCC
CCTCACCCCAATTCCTTTTCTGTACCTAGTGGGATACGGGAAGAAGCGAGGACAGTGGCTTTGT
CAGCTGGAAAGCGACTTTGGAAGGAGCAGACGTGACTATGGGACCTGCCGACTCGAGAGCTGAC
ACATCTCGAATCTTCTTCCTTCAGCTTTCAGCTAGGCCAGAAGGGAGAGTTCTAGAAGGATCTC
AGCTGCCTCCGACCTTCTTCCTTCTCTCCCTGACGCAGCGCTCAGGGAGGCAACGATAAGCAGC
TGATCTTAGAAATCAAGTCCTAACTTTTATGTATGTAAGGAAAGACATTGGTGCTAAAATGAAG
GGGAGCCAAGGCTCAAATAAAAGATGGCTTCCCTGAGCAAAGAAGACCACGGGGTCACTCAAGG
AACTTGGAGGAGAAACTCAGAGTAGACTCTCGAATTGAACAAGCCCAGTGACTCCAGTTTCTGC
AGAGGAGGGTGGGGGCTTCAGTACCATAGAAGGGCACCTGGTCTCCTGGGCGTACACTTGGGCA
GGTTTCTCATGGCACAAGGCTGCCTACAGAGGGGGCTCATAGAGGCTGAAGTCCAGCCTGTGCT
CTGCTCTCTAGGCTGCACATCCTGATGTGGGCTGGGTCTGCCCAGAGTTAGGGATGGCTTCCTG
ATTTGCACAGAGGTACTGTGTGCTCTCGGTGGTCCCGAGGAGGAACTTAAAGCATGCGTACAAG
CCTTTGTGCTTTTCTGCTCAGATGACCTGGAGATATTACCTCTTCTTGGCCACAGTCATTTTCT
CAGGGTGTATACCATGGTTCGTCTGCTAAGAAACTGGGTTCCTGTTTGCAAGGAGAGGGGATCC
AAGAAATGAATATGAAGACTGGTTCCGAGGCACACTAATTATTGTGAAGCCCAGCCTTCCTACA
TCCCACTCCCTCTGCCGTTTAGATGTGTGTGGGACATATGTGGTCTGCCCCTTTCCTGGATCAA
GGCTAGGACAGGCAGGCAGGCAGGCAGGCAGGCTTCTGGTATGTTCTTGGTGGTACATGTGTGC
CCCTCCCCATACAGAACCTTGTACATCAGTCACCTTTAACCTGATTTAGTAGACTTTCCATCTG
AGCTAAGGCTTAGCTGTCAGCTTCAGCAACCTTGCCAGGTACAGGCTGGGTACCCTGTGGCCTG
AGAACTGAGCCCAGAGTTTGACCTGAACATTGAGCCTGGGACCAGGCAGAAGCTGGTCAGAATG
CACTGTCTTCACTTTGGGCCGAACTAGGACCAACCTCACTAACTTGGGCAAGCCAGGGTGAAAC
TTAAACCCTCTTTTATCTTCCACCAACCTGAATCCAGGCTGGAGTTGAAGCTCAGAGATAAAGG
GCTTGCCTGTCAGTCAAGAGACCCTTGGATAGATCCCAGGACTGGAAAATATAAATAATANAAA
ATTATGCTCCCTCCCCCCACCCCACCCCACCACCCCTAGATCTAGGAGGCAGCTGGAAGCCCAG
CTCAAGGAGGCAAGAGGTTCCCCCTGGCTGGTTGCTCTAATTGGCCAGTGATCTCTGCCTGTTG
AATTGGCTTTAGAGTCTCCCAGGACAGCCCCTCCCCTTTGCCTCTCCCCAACTCCAGGAGCCTG
GCTGTCTCTAGTGAAGAGTGGAGATTCAGATTCAGAGGGAGGGAAGGTCTGACCTGTGTGGTGA
CCTGTAACCAGCTGAAGGCAGCAGGGCTTTTGTGGTGTGCTGAGGATGGGGGTGGGAGAGGGGC
TGGGAAACTCAGTGTCGAAATAGCCTAGAGGAACAGAAGCCCCATATTCAGGGGCTGAACTGAT
CTCCTAATTCACAATCCCCAGGGGCATTTCTAAAAGCCAGTGAACAGATCTGGAGGGGAACGTC
CCCCCAGTCCAGTCACTGACTCCCCCGGGGAGGCTGGGGTGGTACACAGGAGGGTGGGGGGTGG
GCACTGTGCCTGGCCCTGTCTCTCTGTTTCAAAGTTTGGCTGTGCTGTTCAGTTGTCCCCAGTG
GCCTTGTCTTGCTTAATCAGAGGTGGAAAAAGATCACCTCCCGGTGACCTCCTTCAGGCCCCAG
GGGATGGGCTGTGTCCAGAGCTGTGTGGCAGAGCTTGTCTCCAGGGTCCAGAGAGGCCCAGCTG
GCCTGCCTTGCTGCCCCAGCCACGAAACCCAAGCCCAACCTCAAGCATGGCAGGGAGTGGGTGT
TGGGGACAGTCTAGCCAAGGCCTCTGTCTGCCCCAAGCTTTCCAGGAACTAAGTAGTGAAGTCA
CTGTGACCGTCCTGGTCAGTGAGGAGAATATTCTGGTGAGAGCTTCCGTTTCTGGGAACTTGAG
AGGGAGTGGGTACGGGTGCATGGAGTAGCAAAAGACCCCAGCCTTCGTGGCTCTGCAGGATGTG
GGGGAATCAGTACTGTGGCCACCATTCCCCCAGTGGAGCAAACTGGCTCTGTGAATATAAGACT
TGTGGAGGCAGGCTATCCTGGCCTCATACCCTGGCTGGACCCAGAGGGACACAGGGTGGAGCCA
CAGGCATTTAAACTTTCTCTGGCTCCCTGTGGGCTGCAGGCCTAGGGGACAGAGCCTCACGGGA
ACAGCAGAACAAAGCTGGTCTCTTCCATAAGTGCCCAGCTTTGGCCAAGGTGCTATGAGATACG
TGGCCCCCAGCTTGCACTGCCCCTCTCTCTACAGCTGTCTGTCTCTACCCCTTCTCTGGGTCCA
CAGCAAGTGACATGGGGAGACCCAGTGAGATGTAGCATTTCCTCCATCCCCAGTTCAGTTGGCA
TGGGGTCTGGGCATTTCTGCCTTAAGGAAAGGAATGGGGACTGTTATGTTTTAACCTGTATATA
ATATTTGACTGTTTTGGTTCTTTATTTGTATACATGTGTAAATACCCTCTCACCCATCAAGTGG
TACCGTTTTTAATAAAACCATTTAAATCAG

hide sequence

RefSeq Acc Id:

XM_039104249 ⟹ XP_038960177

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	105,499,534 - 105,519,951 (-)	NCBI

RefSeq Acc Id:

XR_005501773

RefSeq Status:

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	105,515,550 - 105,520,159 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001388720	(Get FASTA)	NCBI Sequence Viewer
	NP_640351	(Get FASTA)	NCBI Sequence Viewer
	XP_006234786	(Get FASTA)	NCBI Sequence Viewer
	XP_008760301	(Get FASTA)	NCBI Sequence Viewer
	XP_038960177	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAM28890	(Get FASTA)	NCBI Sequence Viewer
	EDL79864	(Get FASTA)	NCBI Sequence Viewer
	EDL79865	(Get FASTA)	NCBI Sequence Viewer
	Q8K589	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_640351 ⟸ NM_139258
- UniProtKB:	A0A8L2Q4K3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEPPQCVEELEDDVFQPEDGEPGTQPGSLLSADLFAQSQLDCPLSRLQLFPLTHCCGPGLRPVS QEDKATQTLSPASPSQGVMLPCGVTEEPQRLFYGNAGYRLPLPASFPAGSALGEQPPEGQFLQH RAEVQIARKLQCIADQFHRLHMQQHQQNRDRAWRQVFLFLQNLALNRRENREGVGPW hide sequence

RefSeq Acc Id:

XP_006234786 ⟸ XM_006234724

- Peptide Label:

isoform X2

- Sequence:

show sequence

MPGAGVFWKQYRAVRGGLLPRQLTPTAVAARARATTSHRSPLEFVPFFPIECGRQVPRVFVTLD
PGAEPWHHDSEAETLSWSHPGDMEPPQCVEELEDDVFQPEDGEPGTQPGSLLSADLFAQSQLDC
PLSRLQLFPLTHCCGPGLRPVSQEDKATQTLSPASPSQGVMLPCGVTEEPQRLFYGNAGYRLPL
PASFPAGSALGEQPPEGQFLQHRAEHQQNRDRAWRQVFLFLQNLALNRRENREGVGPW

hide sequence

RefSeq Acc Id:

XP_008760301 ⟸ XM_008762079

- Peptide Label:

isoform X1

- Sequence:

show sequence

MPGAGVFWKQYRAVRGGLLPRQLTPTAVAARARATTSHRSPLEFVPFFPIECGRQVPRVFVTLD
PGAEPWHHDSEAETLSWSHPGDMEPPQCVEELEDDVFQPEDGEPGTQPGSLLSADLFAQSQLDC
PLSRLQLFPLTHCCGPGLRPVSQEDKATQTLSPASPSQGVMLPCGVTEEPQRLFYAPAEPRPSM
AAGLPLPSKPGLEQTRKQGRGGSLVRLGCSCRIDRPECSLEQTFWEDRYCLVKFCHSEFSFHVY
ILHTPVGSFFPVQNVSWGWGPLSNTVEGEAAVSAG

hide sequence

RefSeq Acc Id:

ENSRNOP00000010381 ⟸ ENSRNOT00000010381

RefSeq Acc Id:	XP_038960177 ⟸ XM_039104249
- Peptide Label:	isoform X3

RefSeq Acc Id:

ENSRNOP00000096398 ⟸ ENSRNOT00000105313

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8K589-F1-model_v2	AlphaFold	Q8K589	1-185	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692310

Promoter ID:

EPDNEW_R2834

Type:

multiple initiation site

Name:

Bmf_1

Description:

Bcl2 modifying factor

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	110,324,078 - 110,324,138	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:628658	AgrOrtholog
BioCyc Gene	G2FUF-48249	BioCyc
Ensembl Genes	ENSRNOG00000007529	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000010381	ENTREZGENE
	ENSRNOP00000010381.4	UniProtKB/TrEMBL
	ENSRNOP00000096398	ENTREZGENE
	ENSRNOP00000096398.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000010381	ENTREZGENE
	ENSRNOT00000010381.5	UniProtKB/TrEMBL
	ENSRNOT00000105313	ENTREZGENE
	ENSRNOT00000105313.1	UniProtKB/TrEMBL
InterPro	BMF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:246142	UniProtKB/Swiss-Prot
NCBI Gene	246142	ENTREZGENE
PANTHER	BCL-2-MODIFYING FACTOR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR32014	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	BMF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Bmf	PhenoGen
UniProt	A0A8I6GLK7_RAT	UniProtKB/TrEMBL
	A0A8L2Q4K3	ENTREZGENE, UniProtKB/TrEMBL
	BMF_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-09-10	Bmf	Bcl2 modifying factor		Bcl-2 modifying factor	Name updated	1299863	APPROVED
2003-02-27	Bmf	Bcl-2 modifying factor			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_domains	contains a BH3 domain	631874

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations