Capn3 (calpain 3) - Rat Genome Database

Name: Capn3
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Capn3 (calpain 3) Rattus norvegicus

Analyze

Symbol:

Capn3

Name:

calpain 3

RGD ID:

2269

Description:

Enables several functions, including calcium-dependent cysteine-type endopeptidase activity; enzyme binding activity; and titin binding activity. Involved in several processes, including response to calcium ion; response to muscle activity; and sodium-dependent self proteolysis. Located in T-tubule and Z disc. Biomarker of hepatocellular carcinoma. Human ortholog(s) of this gene implicated in autosomal dominant limb-girdle muscular dystrophy; autosomal recessive limb-girdle muscular dystrophy type 2A; and muscular dystrophy. Orthologous to human CAPN3 (calpain 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; ammonium chloride.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

calcium-activated neutral proteinase 3; calpain L3; calpain p94; calpain-3; CANP 3; Lp82; Lp84; Lp85; muscle-specific calcium-activated neutral protease 3; p94

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CAPN3 (calpain 3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Capn3 (calpain 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Capn3 (calpain 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LOC100984344 (calpain-3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CAPN3 (calpain 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Capn3 (calpain 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CAPN3 (calpain 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CAPN3 (calpain 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Capn3 (calpain 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	CAPN3 (calpain 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Capn3 (calpain 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	capn3b (calpain 3b)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	capn3a (calpain 3a, (p94))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CalpA	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	clp-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	clp-7	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CalpB	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	clp-3	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	capn3	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	107,407,518 - 107,457,858 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	107,407,850 - 107,457,858 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	111,082,641 - 111,132,438 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	119,678,209 - 119,728,005 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	117,338,596 - 117,388,398 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	112,227,486 - 112,278,408 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	112,228,720 - 112,278,408 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	118,776,357 - 118,825,812 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	106,946,878 - 106,998,274 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	106,843,308 - 106,894,702 (+)	NCBI
Celera	3	106,315,875 - 106,366,640 (+)	NCBI		Celera
Cytogenetic Map	3	q35	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Autosomal Dominant Limb-Girdle Muscular Dystrophy Type 4 (ISO)

autosomal recessive limb-girdle muscular dystrophy (ISO)

autosomal recessive limb-girdle muscular dystrophy type 2A (ISO,ISS)

autosomal recessive limb-girdle muscular dystrophy type 2B (ISO)

Bloom syndrome (ISO)

Cardiac Arrhythmias (ISO)

colorectal cancer (ISO)

congenital muscular dystrophy (ISO)

Familial Idiopathic Inflammatory Myopathy (ISO)

genetic disease (ISO)

hepatocellular carcinoma (IEP)

isolated elevated serum creatine phosphokinase levels (ISO)

limb-girdle muscular dystrophy (ISO)

migraine (ISO)

Mobility Limitation (ISO)

Muscle Weakness (ISO)

muscular disease (ISO)

muscular dystrophy (ISO)

myopathy (ISO)

Paresthesia (ISO)

progressive muscular atrophy (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

amiodarone (ISO)

ammonium chloride (EXP)

amphetamine (EXP)

atrazine (EXP)

benzo[a]pyrene (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP)

cannabidiol (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chlordecone (ISO)

chlorpyrifos (ISO)

chrysene (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

dantrolene (EXP)

dexamethasone (ISO)

dichloroacetic acid (ISO)

dimethylarsinic acid (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

ethanol (ISO)

fenvalerate (EXP)

flavonoids (EXP)

furan (ISO)

genistein (ISO)

gentamycin (EXP)

indometacin (ISO)

leflunomide (ISO)

methylarsonic acid (ISO)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (EXP)

phenobarbital (EXP)

propanal (ISO)

resveratrol (ISO)

SB 431542 (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

succimer (ISO)

sunitinib (ISO)

testosterone (ISO)

topotecan (EXP)

triclosan (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

calcium-dependent self proteolysis (IEA,ISO,ISS)

cellular response to calcium ion (IEA,ISO,ISS)

cellular response to salt stress (IEA,ISO,ISS)

G1 to G0 transition involved in cell differentiation (IEA,ISO)

muscle structure development (ISO,ISS)

myofibril assembly (ISO,ISS)

negative regulation of apoptotic process (IBA,IEA,ISO,ISS)

negative regulation of DNA-templated transcription (IEA,ISO,ISS)

negative regulation of protein sumoylation (IEA,ISO,ISS)

negative regulation of skeletal muscle cell differentiation (ISO)

positive regulation of DNA-templated transcription (IEA,ISO,ISS)

positive regulation of proteolysis (IEA,ISO,ISS)

positive regulation of release of sequestered calcium ion into cytosol (IEA,ISO,ISS)

positive regulation of satellite cell activation involved in skeletal muscle regeneration (IEA,ISO,ISS)

programmed cell death (IEA,ISO)

protein catabolic process (IEA,ISO,ISS)

protein destabilization (IEA,ISO)

protein localization to membrane (IEA,ISO,ISS)

protein-containing complex assembly (IEA,ISO,ISS)

proteolysis (IBA,IDA,IEA,ISO,TAS)

regulation of canonical NF-kappaB signal transduction (IEA,ISO,ISS)

regulation of myoblast differentiation (IEA,ISO)

response to calcium ion (IDA)

response to muscle activity (IDA)

response to xenobiotic stimulus (IEP)

sarcomere organization (IEA,ISO,ISS)

self proteolysis (IDA,ISO)

sodium-dependent self proteolysis (IDA)

Cellular Component

cytoplasm (IBA,IEA,ISO)

cytosol (IEA,ISO,ISS)

myofibril (IDA)

nucleolus (IEA,ISO,ISS)

nucleus (ISO)

plasma membrane (IDA,IEA,ISO,ISS)

protein-containing complex (IEA,ISO,ISS)

T-tubule (IDA)

Z disc (IDA)

Molecular Function

calcium ion binding (IEA,ISO,ISS,TAS)

calcium-dependent cysteine-type endopeptidase activity (IBA,IDA,IEA,ISO,TAS)

catalytic activity (ISO,ISS)

enzyme binding (IPI)

identical protein binding (ISO)

ligase regulator activity (IEA,ISO,ISS)

molecular adaptor activity (IEA,ISO,ISS)

peptidase activity (IDA,ISO)

protein binding (IPI,ISO)

signaling receptor binding (IPI)

sodium ion binding (IEA,ISO,ISS)

structural constituent of muscle (IEA,ISO,ISS)

titin binding (IDA,IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Calpain-3 gene expression is decreased during experimental cancer cachexia.	Busquets S, etal., Biochim Biophys Acta. 2000 Jun 1;1475(1):5-9.
2.	Characterization and regulation of lens-specific calpain Lp82.	Fukiage C, etal., J Biol Chem. 2002 Jun 7;277(23):20678-85. Epub 2002 Mar 19.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
5.	Calpain 3 cleaves filamin C and regulates its ability to interact with gamma- and delta-sarcoglycans.	Guyon JR, etal., Muscle Nerve. 2003 Oct;28(4):472-83.
6.	Calpain 3 is expressed in astrocytes of rat and Microcebus brain.	Konig N, etal., J Chem Neuroanat 2003 Feb;25(2):129-36.
7.	Novel role of calpain-3 in the triad-associated protein complex regulating calcium release in skeletal muscle.	Kramerova I, etal., Hum Mol Genet. 2008 Nov 1;17(21):3271-80. doi: 10.1093/hmg/ddn223. Epub 2008 Aug 1.
8.	Protein for Lp82 calpain is expressed and enzymatically active in young rat lens.	Ma H, etal., Exp Eye Res 1998 Aug;67(2):221-9.
9.	Cloning and expression of mRNA for calpain Lp82 from rat lens: splice variant of p94.	Ma H, etal., Invest Ophthalmol Vis Sci 1998 Feb;39(2):454-61.
10.	Detection and localization of calpain 3-like protease in a neuronal cell line: possible regulation of apoptotic cell death through degradation of nuclear IkappaBalpha.	Marcilhac A, etal., Int J Biochem Cell Biol. 2006;38(12):2128-40. Epub 2006 Jul 5.
11.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
12.	Expression of tropism-related genes in regenerating skeletal muscle of rats treated with cyclosporin-A.	Miyabara EH, etal., Cell Tissue Res. 2005 Mar;319(3):479-89. Epub 2005 Jan 27.
13.	Endogenous calpain-3 activation is primarily governed by small increases in resting cytoplasmic [Ca2+] and is not dependent on stretch.	Murphy RM and Lamb GD, J Biol Chem. 2009 Mar 20;284(12):7811-9. doi: 10.1074/jbc.M808655200. Epub 2009 Jan 14.
14.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
15.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
16.	Skeletal muscle-specific calpain is an intracellular Na+-dependent protease.	Ono Y, etal., J Biol Chem. 2010 Jul 23;285(30):22986-98. doi: 10.1074/jbc.M110.126946. Epub 2010 May 11.
17.	GOA pipeline	RGD automated data pipeline
18.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
19.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
20.	Multiple independent molecular etiology for limb-girdle muscular dystrophy type 2A patients from various geographical origins.	Richard I, etal., Am J Hum Genet. 1997 May;60(5):1128-38.
21.	Molecular cloning of a novel mammalian calcium-dependent protease distinct from both m- and mu-types. Specific expression of the mRNA in skeletal muscle.	Sorimachi H, etal., J Biol Chem 1989 Nov 25;264(33):20106-11.
22.	Myopathy phenotype of transgenic mice expressing active site-mutated inactive p94 skeletal muscle-specific calpain, the gene product responsible for limb girdle muscular dystrophy type 2A.	Tagawa K, etal., Hum Mol Genet 2000 May 22;9(9):1393-402.

Additional References at PubMed

PMID:9642272	PMID:11120559	PMID:12482600	PMID:12658553	PMID:15138196	PMID:16107503	PMID:16857710	PMID:18073330	PMID:18310072	PMID:19295178	PMID:19386580	PMID:19556129
PMID:20139084	PMID:20694146	PMID:23300487	PMID:23357851	PMID:26569227	PMID:29783071	PMID:34638951

Genomics

Comparative Map Data

Capn3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	107,407,518 - 107,457,858 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	107,407,850 - 107,457,858 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	111,082,641 - 111,132,438 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	119,678,209 - 119,728,005 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	117,338,596 - 117,388,398 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	112,227,486 - 112,278,408 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	112,228,720 - 112,278,408 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	118,776,357 - 118,825,812 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	106,946,878 - 106,998,274 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	106,843,308 - 106,894,702 (+)	NCBI
Celera	3	106,315,875 - 106,366,640 (+)	NCBI		Celera
Cytogenetic Map	3	q35	NCBI

CAPN3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	42,359,501 - 42,412,317 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	42,359,498 - 42,412,949 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	42,651,699 - 42,704,515 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	40,427,593 - 40,491,807 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	15	40,427,592 - 40,491,807	NCBI
Celera	15	19,408,011 - 19,472,224 (+)	NCBI		Celera
Cytogenetic Map	15	q15.1	NCBI
HuRef	15	19,499,872 - 19,552,636 (+)	NCBI		HuRef
CHM1_1	15	42,770,186 - 42,823,000 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	15	40,165,536 - 40,218,365 (+)	NCBI		T2T-CHM13v2.0

Capn3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	120,294,074 - 120,335,400 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	120,294,053 - 120,335,399 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	120,463,593 - 120,504,919 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	120,456,019 - 120,504,913 (+)	Ensembl	GRCm38		mm10	GRCm38
GRCm38.p6 Ensembl	2	120,463,572 - 120,504,918 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	120,289,329 - 120,330,655 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	120,155,314 - 120,195,940 (+)	NCBI		MGSCv36	mm8
Celera	2	121,617,948 - 121,659,023 (+)	NCBI		Celera
Cytogenetic Map	2	E5	NCBI
cM Map	2	60.31	NCBI

Capn3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955416	9,070,399 - 9,117,794 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955416	9,070,479 - 9,121,099 (+)	NCBI	ChiLan1.0	ChiLan1.0

LOC100984344
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	15	35,671,129 - 35,815,136 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	21,227,371 - 21,372,406 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	39,458,400 - 39,528,820 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	39,386,377 - 39,468,956 (+)	Ensembl	panpan1.1		panPan2
PanPan1.1 Ensembl	15	39,476,302 - 39,528,820 (+)	Ensembl	panpan1.1		panPan2

CAPN3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	30	9,329,190 - 9,384,622 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	30	9,329,015 - 9,383,772 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	30	9,387,300 - 9,442,600 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	30	9,464,173 - 9,519,888 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	30	9,464,000 - 9,519,096 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	30	9,384,166 - 9,439,578 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	30	9,489,492 - 9,545,424 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	30	9,623,343 - 9,678,674 (+)	NCBI		UU_Cfam_GSD_1.0

Capn3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	87,819,711 - 87,863,585 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936471	5,668,169 - 5,711,075 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936471	5,667,839 - 5,711,822 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CAPN3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	128,960,118 - 129,013,546 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	128,960,117 - 129,013,508 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	143,852,337 - 143,905,767 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3
Pig Cytomap	1	q15-q17	NCBI

CAPN3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	40,568,320 - 40,657,443 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	26	40,568,885 - 40,625,597 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	100,380,987 - 100,442,711 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Capn3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624804	9,473,117 - 9,512,353 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624804	9,473,075 - 9,512,643 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Capn3
178 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	56
Count of miRNA genes:	53
Interacting mature miRNAs:	56
Transcripts:	ENSRNOT00000011761
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	29463235	118376539	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	31172320	163586636	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	38192233	133483320	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	41874578	155617519	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	41874578	155617519	Rat
1581503	Cm58	Cardiac mass QTL 58	2.7	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	43827364	121056321	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	43827364	169034231	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	47233211	147415807	Rat
1358186	Ept2	Estrogen-induced pituitary tumorigenesis QTL 2	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	47233430	110362260	Rat
2292613	Ept16	Estrogen-induced pituitary tumorigenesis QTL 16	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	47233430	110362260	Rat
631665	Bw8	Body weight QTL 8	5.5		body mass (VT:0001259)	body weight (CMO:0000012)	3	50437042	119183768	Rat
724523	Tsu1	Thymus enlargement suppressive QTL 1	3.84		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	3	50437504	115638231	Rat
1582218	Bw74	Body weight QTL 74	3.9	0.0021	body mass (VT:0001259)	body weight (CMO:0000012)	3	53184593	115665732	Rat
1582238	Bw68	Body weight QTL 68	3.2	0.0064	body mass (VT:0001259)	body weight (CMO:0000012)	3	53184593	115665732	Rat
1582239	Epfw1	Epididymal fat weight QTL 1	4.5	0.0006	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	3	53184593	115665732	Rat
1581568	Rf53	Renal function QTL 53			urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	3	56395968	161299569	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	59242096	157323038	Rat
1300111	Rf12	Renal function QTL 12	3.78		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	61017749	121056321	Rat
1582210	Bw71	Body weight QTL 71	3.3	0.0012	body mass (VT:0001259)	body weight (CMO:0000012)	3	64655305	115665732	Rat
1582221	Kidm30	Kidney mass QTL 30	3.5	0.0008	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	3	64655305	115665732	Rat
12879848	Bw181	Body weght QTL 181		0.015	body mass (VT:0001259)	body weight (CMO:0000012)	3	70348525	121056321	Rat
2301414	Kidm37	Kidney mass QTL 37		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	70653097	121056321	Rat
1600376	Arunc5	Aerobic running capacity QTL 5		0.21	exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	3	73376539	118376539	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	78196190	146592722	Rat
2302273	Gluco35	Glucose level QTL 35	5.3	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	80800231	114297550	Rat
631649	Bp123	Blood pressure QTL 123	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	89772419	134772419	Rat
8694437	Bw167	Body weight QTL 167	22.46	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	3	91797474	136797474	Rat
631841	Niddm39	Non-insulin dependent diabetes mellitus QTL 39	3.36		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	94856903	159898684	Rat
724532	Cm17	Cardiac mass QTL 17	2		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	3	95735366	140735366	Rat
1582219	Bw63	Body weight QTL 63	3.8	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	3	96127817	115665732	Rat
1354611	Despr2	Despair related QTL 2	3.03	0.0028	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	3	97084464	142084464	Rat
2293087	Iddm27	Insulin dependent diabetes mellitus QTL 27	2.68		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	97551417	147415807	Rat
2312659	Slep7	Serum leptin concentration QTL 7		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	3	98535255	168026850	Rat
2312670	Bw94	Body weight QTL 94		0.01	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	3	98535255	168026850	Rat
2312673	Scl63	Serum cholesterol level QTL 63		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	98535255	168026850	Rat
2302373	Gluco39	Glucose level QTL 39	5.01		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	3	98535386	161695835	Rat
1582216	Bw65	Body weight QTL 65	6.3		body mass (VT:0001259)	body weight (CMO:0000012)	3	102200529	115665732	Rat

Markers in Region

D3Rat261

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	107,411,819 - 107,412,032 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	112,232,846 - 112,233,058	NCBI	Rnor6.0
Rnor_5.0	3	118,780,585 - 118,780,797	UniSTS	Rnor5.0
RGSC_v3.4	3	106,951,512 - 106,951,725	RGD	RGSC3.4
RGSC_v3.4	3	106,951,513 - 106,951,725	UniSTS	RGSC3.4
RGSC_v3.1	3	106,847,940 - 106,848,153	RGD
Celera	3	106,319,855 - 106,320,067	UniSTS
SHRSP x BN Map	3	52.8698	RGD
SHRSP x BN Map	3	52.8698	UniSTS
Cytogenetic Map	3	q35	UniSTS

RH130533

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	107,457,515 - 107,457,712 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	112,278,066 - 112,278,262	NCBI	Rnor6.0
Rnor_5.0	3	118,825,470 - 118,825,666	UniSTS	Rnor5.0
RGSC_v3.4	3	106,997,932 - 106,998,128	UniSTS	RGSC3.4
Celera	3	106,366,298 - 106,366,494	UniSTS
RH 3.4 Map	3	940.1	UniSTS
Cytogenetic Map	3	q35	UniSTS

RH130699

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	107,405,888 - 107,406,075 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	112,226,671 - 112,226,857	NCBI	Rnor6.0
Rnor_5.0	3	118,774,410 - 118,774,596	UniSTS	Rnor5.0
RGSC_v3.4	3	106,944,931 - 106,945,117	UniSTS	RGSC3.4
Celera	3	106,313,928 - 106,314,114	UniSTS
RH 3.4 Map	3	939.7	UniSTS
Cytogenetic Map	3	q35	UniSTS

RH94578

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	3	q35	UniSTS

Capn3

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	107,408,172 - 107,408,347 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	112,228,953 - 112,229,127	NCBI	Rnor6.0
Rnor_5.0	3	118,776,692 - 118,776,866	UniSTS	Rnor5.0
RGSC_v3.4	3	106,947,213 - 106,947,387	UniSTS	RGSC3.4
Celera	3	106,316,210 - 106,316,384	UniSTS
Cytogenetic Map	3	q35	UniSTS

GDB:595526

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	107,408,074 - 107,408,515 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	112,228,855 - 112,229,295	NCBI	Rnor6.0
Rnor_5.0	3	118,776,594 - 118,777,034	UniSTS	Rnor5.0
RGSC_v3.4	3	106,947,115 - 106,947,555	UniSTS	RGSC3.4
Celera	3	106,316,112 - 106,316,552	UniSTS
Cytogenetic Map	3	q35	UniSTS

SKM-CALPOV

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	107,408,069 - 107,408,327 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	112,228,850 - 112,229,107	NCBI	Rnor6.0
Rnor_5.0	3	118,776,589 - 118,776,846	UniSTS	Rnor5.0
RGSC_v3.4	3	106,947,110 - 106,947,367	UniSTS	RGSC3.4
Celera	3	106,316,107 - 106,316,364	UniSTS
Cytogenetic Map	3	q35	UniSTS

CANP3SKM

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	107,443,333 - 107,444,231 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	112,263,884 - 112,264,781	NCBI	Rnor6.0
Rnor_5.0	3	118,811,288 - 118,812,185	UniSTS	Rnor5.0
RGSC_v3.4	3	106,983,750 - 106,984,647	UniSTS	RGSC3.4
Celera	3	106,352,115 - 106,353,012	UniSTS
Cytogenetic Map	3	q35	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium							8	11					8
Low		18	23	16	17	16			63	3	31	11
Below cutoff	3	25	27	18	2	18			11	32	10

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_017117	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006234728	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006234729	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008762080	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008762081	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017591508	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039104419	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039104420	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039104421	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039104422	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF052540	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF061726	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF173834	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF184950	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	J05121	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000118	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U96367	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000011761 ⟹ ENSRNOP00000011761

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	107,407,850 - 107,457,858 (+)	Ensembl
Rnor_6.0 Ensembl	3	112,228,919 - 112,278,038 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000079079 ⟹ ENSRNOP00000069651

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	107,407,850 - 107,457,858 (+)	Ensembl
Rnor_6.0 Ensembl	3	112,228,720 - 112,278,022 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000080533 ⟹ ENSRNOP00000071494

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	107,421,257 - 107,457,856 (+)	Ensembl
Rnor_6.0 Ensembl	3	112,242,270 - 112,278,408 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000082876 ⟹ ENSRNOP00000075081

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	107,421,257 - 107,457,856 (+)	Ensembl
Rnor_6.0 Ensembl	3	112,242,326 - 112,278,401 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000108270 ⟹ ENSRNOP00000080932

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	107,407,850 - 107,457,858 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000109382 ⟹ ENSRNOP00000079180

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	107,407,850 - 107,457,858 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000115649 ⟹ ENSRNOP00000087393

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	107,421,257 - 107,457,856 (+)	Ensembl

RefSeq Acc Id:

NM_017117 ⟹ NP_058813

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	107,407,838 - 107,457,858 (+)	NCBI
Rnor_6.0	3	112,228,618 - 112,278,408 (+)	NCBI
Rnor_5.0	3	118,776,357 - 118,825,812 (+)	NCBI
RGSC_v3.4	3	106,946,878 - 106,998,274 (+)	RGD
Celera	3	106,315,875 - 106,366,640 (+)	RGD

Sequence:

show sequence

TTTTCTTTTTTTCCTCTGGCAAGCCTGCTGCTGGTAGGCACCCCCAGGTAGAAGCTGCGTCTAA
ATCCTTTATTGCCTCTTCCTCAGGAATACCTATTGCTCTAGGGTCATAGTTCACCTATTTAAGC
TGGTCAGAGGCCAGCCAATTTTCTGATAGGATTTAAACTTTGAAGAGACTGTAGCCATTTTTTT
CCTCAGATGACAGAATCACTTCAACTTCCACTTTGTAATCGCTTCCTTTCCTTGAAGGTAGCTG
AATCTTGTTTTCTTTAAAAACGTCTTCCTTCCAAAGTTGCCTGCCATGCCGACCGTTATTAGTC
CAACTGTGGCCCCAAGGACAGGAGCTGAGCCCAGGTCCCCAGGGCCAGTTCCTCACCCAGCTCA
AGGCAAGACCACTGAGGCTGGAGGTGGACACCCGGGTGGCATCTATTCAGCCATCATCAGCCGC
AATTTTCCGATCATTGGTGTGAAAGAGAAGACATTCGAGCAGCTCCACAAGAAGTGCCTAGAGA
AGAAAGTTCTTTACCTGGATCCCGAGTTCCCACCGGATGAGACCTCTCTCTTTTACAGCCAGAA
GTTCCCCATCCAGTTCGTCTGGAAGAGACCTCCGGAAATTTGTGAGAATCCCCGATTTATCATT
GGTGGAGCCAACAGGACTGACATCTGCCAAGGAGATCTAGGGGACTGCTGGCTTCTTGCAGCCA
TTGCCTGTCTGACCCTGAATGAGCGACTGCTTTTCCGAGTTATACCTCATGATCAAAGTTTCAC
TGAAAACTACGCAGGGATCTTCCACTTCCAGTTCTGGCGCTATGGAGACTGGGTAGATGTGGTT
ATTGACGACTGTCTGCCGACATACAACAACCAGCTGGTCTTCACCAAATCCAACCACCGCAATG
AGTTCTGGAGTGCTCTACTGGAGAAAGCATATGCCAAGCTCCATGGTTCCTATGAAGCTCTGAA
AGGTGGGAACACCACAGAAGCCATGGAGGACTTCACAGGAGGGGTGACAGAGTTTTTTGAGATC
AAGGATGCTCCGAGTGACATGTACAAGATCATGAGGAAAGCTATCGAGAGAGGCTCCCTCATGG
GCTGCTCCATTGATGATGGCACCAACATGACTTATGGAACCTCTCCTTCTGGTCTGAACATGGG
GGAATTGATTGCGCGGATGGTGAGAAATATGGATAACTCGCTGCTCAGAGACTCAGACCTGGAC
CCCAGGGCCTCAGATGACAGACCGTCACGGACAATTGTTCCGGTGCAGTATGAAACAAGAATGG
CCTGTGGACTGGTGAAAGGGCACGCCTATTCAGTCACTGGGCTGGAGGAGGCCCTGTTCAAAGG
CGAGAAGGTGAAGCTGGTGCGGCTGCGGAACCCCTGGGGCCAGGTGGAGTGGAACGGCTCTTGG
AGTGATGGTTGGAAGGACTGGAGCTTTGTGGACAAAGACGAGAAGGCCCGTCTGCAGCACCAGG
TCACCGAGGATGGAGAGTTCTGGATGTCATATGATGACTTTGTCTACCATTTCACAAAGCTGGA
GATCTGCAACCTCACAGCTGATGCCCTGGAGTCCGATAAGCTTCAGACCTGGACAGTGTCTGTA
AATGAGGGCCGCTGGGTGAGGGGCTGTTCTGCTGGAGGCTGCCGGAACTTCCCAGACACTTTCT
GGACCAACCCGCAGTACCGTCTCAAGCTCCTGGAGGAGGATGATGACCCTGATGACTCTGAGGT
GATTTGCAGCTTCCTCGTGGCTCTGATGCAGAAAAATCGGCGCAAGGACCGGAAGCTGGGGGCC
AACCTCTTCACCATTGGCTTCGCTATCTACGAGGTTCCCAAAGAGATGCACGGGAATAAGCAAC
ACCTGCAGAAGGACTTCTTCTTGTACAATGCCTCCAAGGCCAGGAGCAAAACCTACATCAACAT
GCGGGAGGTGTCCCAGCGCTTCCGCCTGCCGCCCAGCGAGTATGTCATTGTCCCCTCCACTTAC
GAGCCCCATCAGGAGGGGGAATTCATCCTCCGGGTCTTCTCTGAAAAGAGGAATCTCTCTGAGG
AAGCTGAGAATACAATCTCTGTGGACCGGCCAGTGAAAAAGAAAAAAAACAAGCCCATCATCTT
CGTTTCAGACAGAGCAAACAGCAACAAGGAGCTGGGTGTGGACCAGGAGGCAGAGGAGGGCAAA
GACAAAACAGGGCCGGATAAACAAGGGGAAAGCCCACAGCCACGGCCTGGCCACACAGACCAGG
AGAGTGAGGAGCAGCAGCAATTCCGGAACATCTTCAGGCAGATTGCAGGCGACGACATGGAGAT
CTGTGCGGATGAACTCAAGAATGTCCTTAATACGGTGGTGAACAAACACAAGGACCTGAAGACA
CAAGGGTTCACTCTGGAGTCCTGCAGAAGCATGATAGCTCTCATGGATACAGATGGCTCTGGGA
GACTGAATCTTCAAGAGTTCCATCACCTCTGGAAAAAGATCAAGGCCTGGCAGAAAATCTTCAA
ACACTATGACACTGACCATTCTGGTACCATCAATAGCTATGAGATGCGAAATGCAGTCAATGAT
GCAGGCTTCCATCTCAACAGCCAACTCTATGACATCATCACCATGCGCTACGCAGACAAACACA
TGAACATCGACTTTGACAGCTTCATCTGCTGCTTCGTCAGGCTGGAAGGGATGTTCAGAGCTTT
TCACGCATTTGACAAGGATGGAGATGGCATCATCAAACTGAACGTACTTGAGTGGCTGCAGCTT
ACCATGTATGCCTGAACCAGATGACCTCATGTAAGATCAACCAGGATTCCATCTCAACACGACA
CAGCTAGGGCTGTTTACCACAAGGAACCCAGTAGGCACACCTCCACCAAACTGGGCTCCTGGTC
ACGTTCCTTCTCCACTTTGACCCAAGTCTTGGTGCACAGCCACCTCAAGTGTCTGGCTTGCTGG
GAGCTCTGCAGACGCTGTCTACATAGCTTGTAACTGGGTTGTCCACAGCCCTGTCACCATCTGC
ACTCAGTTCTGCCAGTTTTAGGGTGGGTCTACTCTGGGGTCCATAGGGTGTGGATACCTGACAA
AAATGTGGCTACACTTCTGAAAGAATCTATCTAAATAAAGGCACGCACATGGCTGGTTCCACCA
TT

hide sequence

RefSeq Acc Id:

XM_006234728 ⟹ XP_006234790

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	107,421,308 - 107,457,856 (+)	NCBI
Rnor_6.0	3	112,242,243 - 112,278,406 (+)	NCBI
Rnor_5.0	3	118,776,357 - 118,825,812 (+)	NCBI

Sequence:

show sequence

GCTCCGGGCCATTCACCAGAGGATTAGGCCTGGGCTGAGGGTGCAGCAGGAGAGGCCGCAGGGA
AGGCCGGGTTCCACTGCTCGTCATCATGCCCTACCTGCTGCCGGGATTCTTCTGTGACAGAGTG
ATCAGAGAAAGGGACAGGAGAAATGGAGAGGGCACCGTCTCACAGCCTCTCAAGTTTGAGGGGC
AGGATTTTGTCGTTCTCAAACAACGGTGTCTGGCTCAGAAGTGCCTCTTTGAAGATCGAGTCTT
CCCAGCAGGTACACAGGCCCTTGGCTCACATGAGCTGAGCCAGAAAGCCAAGATGAAGGCCATC
ACTTGGAAGAGGCCAAAGGAAATTTGTGAGAATCCCCGATTTATCATTGGTGGAGCCAACAGGA
CTGACATCTGCCAAGGAGATCTAGGGGACTGCTGGTTTCTTGCAGCCATTGCCTGTCTGACCCT
GAATGAGCGACTGCTTTTCCGAGTTATACCTCATGATCAAAGTTTCACTGAAAACTACGCAGGG
ATCTTCCACTTCCAGTTCTGGCGCTATGGAGACTGGGTAGATGTGGTTATTGACGACTGTCTGC
CGACATACAACAACCAGCTGGTCTTCACCAAATCCAACCACCGCAATGAGTTCTGGAGTGCTCT
ACTGGAGAAAGCATATGCCAAGCTCCATGGTTCCTATGAAGCTCTGAAAGGTGGGAACACCACA
GAAGCCATGGAGGACTTCACAGGAGGGGTGACAGAGTTTTTTGAGATCAAGGATGCTCCGAGTG
ACATGTACAAGATCATGAGGAAAGCTATCGAGAGAGGCTCCCTCATGGGCTGCTCCATTGATGA
TGGCACCAACATGACTTATGGAACCTCTCCTTCTGGTCTGAACATGGGGGAATTGATTGCGCGG
ATGGTGAGAAATATGGATAACTCGCTGCTCAGAGACTCAGACCTGGACCCCAGGGCCTCAGATG
ACAGACCGTCACGGACAATTGTTCCGGTGCAGTATGAAACAAGAATGGCCTGTGGACTGGTGAA
AGGGCACGCCTATTCAGTCACTGGGCTGGAGGAGGCCCTGTTCAAAGGCGAGAAGGTGAAGCTG
GTGCGGCTGCGGAACCCCTGGGGCCAGGTGGAGTGGAACGGCTCTTGGAGTGATGGTTGGAAGG
ACTGGAGCTTTGTGGACAAAGACGAGAAGGCCCGTCTGCAGCACCAGGTCACCGAGGATGGAGA
GTTCTGGATGTCATATGATGACTTTGTCTACCATTTCACAAAGCTGGAGATCTGCAACCTCACA
GCTGATGCCCTGGAGTCCGATAAGCTTCAGACCTGGACAGTGTCTGTAAATGAGGGCCGCTGGG
TGAGGGGCTGTTCTGCTGGAGGCTGCCGGAACTTCCCAGACACTTTCTGGACCAACCCGCAGTA
CCGTCTCAAGCTCCTGGAGGAGGATGATGACCCTGATGACTCTGAGGTGATTTGCAGCTTCCTC
GTGGCTCTGATGCAGAAAAATCGGCGCAAGGACCGGAAGCTGGGGGCCAACCTCTTCACCATTG
GCTTCGCTATCTACGAGGTTCCCAAAGAGATGCACGGGAATAAGCAACACCTGCAGAAGGACTT
CTTCTTGTACAATGCCTCCAAGGCCAGGAGCAAAACCTACATCAACATGCGGGAGGTGTCCCAG
CGCTTCCGCCTGCCGCCCAGCGAGTATGTCATTGTCCCCTCCACTTACGAGCCCCATCAGGAGG
GGGAATTCATCCTCCGGGTCTTCTCTGAAAAGAGGAATCTCTCTGAGGAAGCTGAGAATACAAT
CTCTGTGGACCGGCCAGTGCCACGGCCTGGCCACACAGACCAGGAGAGTGAGGAGCAGCAGCAA
TTCCGGAACATCTTCAGGCAGATTGCAGGCGACGACATGGAGATCTGTGCGGATGAACTCAAGA
ATGTCCTTAATACGGTGGTGAACAAACGTGAGCGACTCGCGCCAGACGTGGGGGATGGGCAGGG
GCCCCAGCTGTCTGAAAGCAGCTCCTCACCCTTCTCCATCCCCCCAGACAAGGACCTGAAGACA
CAAGGGTTCACTCTGGAGTCCTGCAGAAGCATGATAGCTCTCATGGATACAGATGGCTCTGGGA
GACTGAATCTTCAAGAGTTCCATCACCTCTGGAAAAAGATCAAGGCCTGGCAGAAAATCTTCAA
ACACTATGACACTGACCATTCTGGTACCATCAATAGCTATGAGATGCGAAATGCAGTCAATGAT
GCAGGCTTCCATCTCAACAGCCAACTCTATGACATCATCACCATGCGCTACGCAGACAAACACA
TGAACATCGACTTTGACAGCTTCATCTGCTGCTTCGTCAGGCTGGAAGGGATGTTCAGAGCTTT
TCACGCATTTGACAAGGATGGAGATGGCATCATCAAACTGAACGTACTTGAGTGGCTGCAGCTT
ACCATGTATGCCTGAACCAGATGACCTCATGTAAGATCAACCAGGATTCCATCTCAACACGACA
CAGCTAGGGCTGTTTACCACAAGGAACCCAGTAGGCACACCTCCACCAAACTGGGCTCCTGGTC
ACGTTCCTTCTCCACTTTGACCCAAGTCTTGGTGCACAGCCACCTCAAGTGTCTGGCTTGCTGG
GAGCTCTGCAGACGCTGTCTACATAGCTTGTAACTGGGTTGTCCACAGCCCTGTCACCATCTGC
ACTCAGTTCTGCCAGTTTTAGGGTGGGTCTACTCTGGGGTCCATAGGGTGTGGATACCTGACAA
AAATGTGGCTACATTCTGAAAGAATCTATCTAAATAAAGGCACGCACATGGCTGGTTCCACCA

hide sequence

RefSeq Acc Id:

XM_006234729 ⟹ XP_006234791

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	107,421,264 - 107,457,856 (+)	NCBI
Rnor_6.0	3	112,242,247 - 112,278,406 (+)	NCBI
Rnor_5.0	3	118,776,357 - 118,825,812 (+)	NCBI

Sequence:

show sequence

CGGGCCATTCACCAGAGGATTAGGCCTGGGCTGAGGGTGCAGCAGGAGAGGCCGCAGGGAAGGC
CGGGTTCCACTGCTCGTCATCATGCCCTACCTGCTGCCGGGATTCTTCTGTGACAGAGTGATCA
GAGAAAGGGACAGGAGAAATGGAGAGGGCACCGTCTCACAGCCTCTCAAGTTTGAGGGGCAGGA
TTTTGTCGTTCTCAAACAACGGTGTCTGGCTCAGAAGTGCCTCTTTGAAGATCGAGTCTTCCCA
GCAGGTACACAGGCCCTTGGCTCACATGAGCTGAGCCAGAAAGCCAAGATGAAGGCCATCACTT
GGAAGAGGCCAAAGGAAATTTGTGAGAATCCCCGATTTATCATTGGTGGAGCCAACAGGACTGA
CATCTGCCAAGGAGATCTAGGGGACTGCTGGTTTCTTGCAGCCATTGCCTGTCTGACCCTGAAT
GAGCGACTGCTTTTCCGAGTTATACCTCATGATCAAAGTTTCACTGAAAACTACGCAGGGATCT
TCCACTTCCAGTTCTGGCGCTATGGAGACTGGGTAGATGTGGTTATTGACGACTGTCTGCCGAC
ATACAACAACCAGCTGGTCTTCACCAAATCCAACCACCGCAATGAGTTCTGGAGTGCTCTACTG
GAGAAAGCATATGCCAAGCTCCATGGTTCCTATGAAGCTCTGAAAGGTGGGAACACCACAGAAG
CCATGGAGGACTTCACAGGAGGGGTGACAGAGTTTTTTGAGATCAAGGATGCTCCGAGTGACAT
GTACAAGATCATGAGGAAAGCTATCGAGAGAGGCTCCCTCATGGGCTGCTCCATTGATGATGGC
ACCAACATGACTTATGGAACCTCTCCTTCTGGTCTGAACATGGGGGAATTGATTGCGCGGATGG
TGAGAAATATGGATAACTCGCTGCTCAGAGACTCAGACCTGGACCCCAGGGCCTCAGATGACAG
ACCGTCACGGACAATTGTTCCGGTGCAGTATGAAACAAGAATGGCCTGTGGACTGGTGAAAGGG
CACGCCTATTCAGTCACTGGGCTGGAGGAGGCCCTGTTCAAAGGCGAGAAGGTGAAGCTGGTGC
GGCTGCGGAACCCCTGGGGCCAGGTGGAGTGGAACGGCTCTTGGAGTGATGGTTGGAAGGACTG
GAGCTTTGTGGACAAAGACGAGAAGGCCCGTCTGCAGCACCAGGTCACCGAGGATGGAGAGTTC
TGGATGTCATATGATGACTTTGTCTACCATTTCACAAAGCTGGAGATCTGCAACCTCACAGCTG
ATGCCCTGGAGTCCGATAAGCTTCAGACCTGGACAGTGTCTGTAAATGAGGGCCGCTGGGTGAG
GGGCTGTTCTGCTGGAGGCTGCCGGAACTTCCCAGACACTTTCTGGACCAACCCGCAGTACCGT
CTCAAGCTCCTGGAGGAGGATGATGACCCTGATGACTCTGAGGTGATTTGCAGCTTCCTCGTGG
CTCTGATGCAGAAAAATCGGCGCAAGGACCGGAAGCTGGGGGCCAACCTCTTCACCATTGGCTT
CGCTATCTACGAGGTTCCCAAAGAGATGCACGGGAATAAGCAACACCTGCAGAAGGACTTCTTC
TTGTACAATGCCTCCAAGGCCAGGAGCAAAACCTACATCAACATGCGGGAGGTGTCCCAGCGCT
TCCGCCTGCCGCCCAGCGAGTATGTCATTGTCCCCTCCACTTACGAGCCCCATCAGGAGGGGGA
ATTCATCCTCCGGGTCTTCTCTGAAAAGAGGAATCTCTCTGAGGAAGCTGAGAATACAATCTCT
GTGGACCGGCCAGTGCCACGGCCTGGCCACACAGACCAGGAGAGTGAGGAGCAGCAGCAATTCC
GGAACATCTTCAGGCAGATTGCAGGCGACGACATGGAGATCTGTGCGGATGAACTCAAGAATGT
CCTTAATACGGTGGTGAACAAACACAAGGACCTGAAGACACAAGGGTTCACTCTGGAGTCCTGC
AGAAGCATGATAGCTCTCATGGATACAGATGGCTCTGGGAGACTGAATCTTCAAGAGTTCCATC
ACCTCTGGAAAAAGATCAAGGCCTGGCAGAAAATCTTCAAACACTATGACACTGACCATTCTGG
TACCATCAATAGCTATGAGATGCGAAATGCAGTCAATGATGCAGGCTTCCATCTCAACAGCCAA
CTCTATGACATCATCACCATGCGCTACGCAGACAAACACATGAACATCGACTTTGACAGCTTCA
TCTGCTGCTTCGTCAGGCTGGAAGGGATGTTCAGAGCTTTTCACGCATTTGACAAGGATGGAGA
TGGCATCATCAAACTGAACGTACTTGAGTGGCTGCAGCTTACCATGTATGCCTGAACCAGATGA
CCTCATGTAAGATCAACCAGGATTCCATCTCAACACGACACAGCTAGGGCTGTTTACCACAAGG
AACCCAGTAGGCACACCTCCACCAAACTGGGCTCCTGGTCACGTTCCTTCTCCACTTTGACCCA
AGTCTTGGTGCACAGCCACCTCAAGTGTCTGGCTTGCTGGGAGCTCTGCAGACGCTGTCTACAT
AGCTTGTAACTGGGTTGTCCACAGCCCTGTCACCATCTGCACTCAGTTCTGCCAGTTTTAGGGT
GGGTCTACTCTGGGGTCCATAGGGTGTGGATACCTGACAAAAATGTGGCTACATTCTGAAAGAA
TCTATCTAAATAAAGGCACGCACATGGCTGGTTCCACCA

hide sequence

RefSeq Acc Id:

XM_008762081 ⟹ XP_008760303

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	107,407,522 - 107,457,856 (+)	NCBI
Rnor_6.0	3	112,227,487 - 112,278,406 (+)	NCBI

Sequence:

show sequence

GCGCGCGCGTGTTTGTGTGGGTGAGACGGGCATGAACATGAACACATGGGCGTGCCATGCCACA
CAGAGGAGGACAGTCTGGGGTGTTGGCCCTTGCCTTCCACCTTATTTGTGACACAGTGAGACAT
AGTCTTTTTGTCATTTTTTGCTGTGTGGGCTGACAACCTGCCGATGCTTCTATGGCTTCTCTGC
CTGTGCCTCTCATCCCACTGGGGATATACTGGGATGGCAGACATGTTACTGCACTAGTTTTATG
TGGGAGCTCAGATCCTCACTTGTAAATGGCAAGTGCTACCACTGAGCCATCTCTCCTGCCCTAT
GCCCCCCACCACAGTTGTCACCTCCTACCCTTTCCTCTCTTCTAAACTTGGATCTATAGGGCTG
GTCACTTAGGAACAGGCACAGCTGCAAGCTAGGACAAGCCTCTACTCTGTCATATGTCAGATAT
AACCATTTCATTATGACCCAGAGAGCAACTACCATGGTAAAACAAAAACAAAAACAAAACAAAA
CAAAACAAATACAGGTAGAAGCCAGGCAATCAACTCCCTCTTTGATTCCCACTTAAAAGCCCTG
AAGCTGAGTCCTCACTAGGCATGACATCTTAGGACTCGACATTAACCTGGCTCTATTTCCAGTT
CTGTCTAGACGCTGATGTGGTGCAGCTAAATAATCTAGCGCAGAATCTACTAGGATATACATTG
TGTAATAGACTTGATCTCACTGTGTCCAGTGGGCAAGAAGAGAGAGATTTCCTTGGCTGGAAAT
TCTGCTGAGTGGCATTTTCTACCCACTTGGATGGAAAGCTGACTCCAGAATATTCTAGAAAAGA
TACTGACTCTAAAATACTCTTTTCCATGTATCCAGCGGCTACTGCTCCAGTAGCCTGTATGGCT
GCCTAGTCCTTAACACAAGTTGCTGATTTCTGTCGTTCACTTGTCTCAGATACTCTCACTTCTT
GACAAGCCGAGTTCCTTAATGTCAATTCAGAAATATCTCTAGCTAGGTCCTTCCCTACCACTCA
GTCTAGCCACGCACTGGCCTCTTGCTTCCATGTTCACGATCTCACTTCACATCTATTTTTAGTT
TTCCTGGCTTAAGCTTCTTCAGGCCACTGAAACACAACCCTCATTCTCTTTTTCTCCTCTGGCA
AGCCTGCTGCTGGTAGGCACCCCCAGGTAGAAGCTGCGTCTAAATCCTTTATTGCCTCTTCCTC
AGGAATACCTATTGCTCTAGGGTCATAGTTCACCTATTTAAGCTGGTCAGAGGCCAGCCAATTT
TCTGATAGGATTTAAACTTTGAAGAGACTGTAGCCATTTTTTTCCTCAGATGACAGAATCACTT
CAACTTCCACTTTGTAATCGCTTCCTTTCCTTGAAGGTAGCTGAATCTTGTTTTCTTTAAAAAC
GTCTTCCTTCCAAAGTTGCCTGCCATGCCGACCGTTATTAGTCCAACTGTGGCCCCAAGGACAG
GAGCTGAGCCCAGGTCCCCAGGGCCAGTTCCTCACCCAGCTCAAGGCAAGACCACTGAGGCTGG
AGGTGGACACCCGGGTGGCATCTATTCAGCCATCATCAGCCGCAATTTTCCGATCATTGGTGTG
AAAGAGAAGACATTCGAGCAGCTCCACAAGAAGTGCCTAGAGAAGAAAGTTCTTTACCTGGATC
CCGAGTTCCCACCGGATGAGACCTCTCTCTTTTACAGCCAGAAGTTCCCCATCCAGTTCGTCTG
GAAGAGACCTCCGGAAATTTGTGAGAATCCCCGATTTATCATTGGTGGAGCCAACAGGACTGAC
ATCTGCCAAGGAGATCTAGGGGACTGCTGGTTTCTTGCAGCCATTGCCTGTCTGACCCTGAATG
AGCGACTGCTTTTCCGAGTTATACCTCATGATCAAAGTTTCACTGAAAACTACGCAGGGATCTT
CCACTTCCAGTTCTGGCGCTATGGAGACTGGGTAGATGTGGTTATTGACGACTGTCTGCCGACA
TACAACAACCAGCTGGTCTTCACCAAATCCAACCACCGCAATGAGTTCTGGAGTGCTCTACTGG
AGAAAGCATATGCCAAGCTCCATGGTTCCTATGAAGCTCTGAAAGGTGGGAACACCACAGAAGC
CATGGAGGACTTCACAGGAGGGGTGACAGAGTTTTTTGAGATCAAGGATGCTCCGAGTGACATG
TACAAGATCATGAGGAAAGCTATCGAGAGAGGCTCCCTCATGGGCTGCTCCATTGATGATGGCA
CCAACATGACTTATGGAACCTCTCCTTCTGGTCTGAACATGGGGGAATTGATTGCGCGGATGGT
GAGAAATATGGATAACTCGCTGCTCAGAGACTCAGACCTGGACCCCAGGGCCTCAGATGACAGA
CCGTCACGGACAATTGTTCCGGTGCAGTATGAAACAAGAATGGCCTGTGGACTGGTGAAAGGGC
ACGCCTATTCAGTCACTGGGCTGGAGGAGGCCCTGTTCAAAGGCGAGAAGGTGAAGCTGGTGCG
GCTGCGGAACCCCTGGGGCCAGGTGGAGTGGAACGGCTCTTGGAGTGATGGTTGGAAGGACTGG
AGCTTTGTGGACAAAGACGAGAAGGCCCGTCTGCAGCACCAGGTCACCGAGGATGGAGAGTTCT
GGATGTCATATGATGACTTTGTCTACCATTTCACAAAGCTGGAGATCTGCAACCTCACAGCTGA
TGCCCTGGAGTCCGATAAGCTTCAGACCTGGACAGTGTCTGTAAATGAGGGCCGCTGGGTGAGG
GGCTGTTCTGCTGGAGGCTGCCGGAACTTCCCAGACACTTTCTGGACCAACCCGCAGTACCGTC
TCAAGCTCCTGGAGGAGGATGATGACCCTGATGACTCTGAGGTGATTTGCAGCTTCCTCGTGGC
TCTGATGCAGAAAAATCGGCGCAAGGACCGGAAGCTGGGGGCCAACCTCTTCACCATTGGCTTC
GCTATCTACGAGGTTCCCAAAGAGATGCACGGGAATAAGCAACACCTGCAGAAGGACTTCTTCT
TGTACAATGCCTCCAAGGCCAGGAGCAAAACCTACATCAACATGCGGGAGGTGTCCCAGCGCTT
CCGCCTGCCGCCCAGCGAGTATGTCATTGTCCCCTCCACTTACGAGCCCCATCAGGAGGGGGAA
TTCATCCTCCGGGTCTTCTCTGAAAAGAGGAATCTCTCTGAGGAAGCTGAGAATACAATCTCTG
TGGACCGGCCAGTGCCACGGCCTGGCCACACAGACCAGGAGAGTGAGGAGCAGCAGCAATTCCG
GAACATCTTCAGGCAGATTGCAGGCGACGACATGGAGATCTGTGCGGATGAACTCAAGAATGTC
CTTAATACGGTGGTGAACAAACACAAGGACCTGAAGACACAAGGGTTCACTCTGGAGTCCTGCA
GAAGCATGATAGCTCTCATGGATACAGATGGCTCTGGGAGACTGAATCTTCAAGAGTTCCATCA
CCTCTGGAAAAAGATCAAGGCCTGGCAGAAAATCTTCAAACACTATGACACTGACCATTCTGGT
ACCATCAATAGCTATGAGATGCGAAATGCAGTCAATGATGCAGGCTTCCATCTCAACAGCCAAC
TCTATGACATCATCACCATGCGCTACGCAGACAAACACATGAACATCGACTTTGACAGCTTCAT
CTGCTGCTTCGTCAGGCTGGAAGGGATGTTCAGAGCTTTTCACGCATTTGACAAGGATGGAGAT
GGCATCATCAAACTGAACGTACTTGAGTGGCTGCAGCTTACCATGTATGCCTGAACCAGATGAC
CTCATGTAAGATCAACCAGGATTCCATCTCAACACGACACAGCTAGGGCTGTTTACCACAAGGA
ACCCAGTAGGCACACCTCCACCAAACTGGGCTCCTGGTCACGTTCCTTCTCCACTTTGACCCAA
GTCTTGGTGCACAGCCACCTCAAGTGTCTGGCTTGCTGGGAGCTCTGCAGACGCTGTCTACATA
GCTTGTAACTGGGTTGTCCACAGCCCTGTCACCATCTGCACTCAGTTCTGCCAGTTTTAGGGTG
GGTCTACTCTGGGGTCCATAGGGTGTGGATACCTGACAAAAATGTGGCTACATTCTGAAAGAAT
CTATCTAAATAAAGGCACGCACATGGCTGGTTCCACCA

hide sequence

RefSeq Acc Id:

XM_039104419 ⟹ XP_038960347

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	107,407,521 - 107,457,856 (+)	NCBI

RefSeq Acc Id:

XM_039104420 ⟹ XP_038960348

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	107,421,308 - 107,457,856 (+)	NCBI

RefSeq Acc Id:

XM_039104421 ⟹ XP_038960349

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	107,407,518 - 107,457,856 (+)	NCBI

RefSeq Acc Id:

XM_039104422 ⟹ XP_038960350

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	3	107,421,266 - 107,457,856 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_058813	(Get FASTA)	NCBI Sequence Viewer
	XP_006234790	(Get FASTA)	NCBI Sequence Viewer
	XP_006234791	(Get FASTA)	NCBI Sequence Viewer
	XP_008760303	(Get FASTA)	NCBI Sequence Viewer
	XP_038960347	(Get FASTA)	NCBI Sequence Viewer
	XP_038960348	(Get FASTA)	NCBI Sequence Viewer
	XP_038960349	(Get FASTA)	NCBI Sequence Viewer
	XP_038960350	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA41790	(Get FASTA)	NCBI Sequence Viewer
	AAC04848	(Get FASTA)	NCBI Sequence Viewer
	AAC15423	(Get FASTA)	NCBI Sequence Viewer
	AAC23592	(Get FASTA)	NCBI Sequence Viewer
	AAD51699	(Get FASTA)	NCBI Sequence Viewer
	AAD56236	(Get FASTA)	NCBI Sequence Viewer
	EDL79941	(Get FASTA)	NCBI Sequence Viewer
	EDL79942	(Get FASTA)	NCBI Sequence Viewer
	EDL79943	(Get FASTA)	NCBI Sequence Viewer
	EDL79944	(Get FASTA)	NCBI Sequence Viewer
	EDL79945	(Get FASTA)	NCBI Sequence Viewer
	EDL79946	(Get FASTA)	NCBI Sequence Viewer
	EDL79947	(Get FASTA)	NCBI Sequence Viewer
	EDL79948	(Get FASTA)	NCBI Sequence Viewer
	EDL79949	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000011761.7
	ENSRNOP00000069651.2
	ENSRNOP00000071494
	ENSRNOP00000071494.2
	ENSRNOP00000075081
	ENSRNOP00000075081.1
	ENSRNOP00000079180
	ENSRNOP00000079180.1
	ENSRNOP00000080932
	ENSRNOP00000080932.1
	ENSRNOP00000087393.1
GenBank Protein	P16259	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_058813 ⟸ NM_017117

- UniProtKB:

P16259 (UniProtKB/Swiss-Prot), A0A8I5ZRY1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPTVISPTVAPRTGAEPRSPGPVPHPAQGKTTEAGGGHPGGIYSAIISRNFPIIGVKEKTFEQL
HKKCLEKKVLYLDPEFPPDETSLFYSQKFPIQFVWKRPPEICENPRFIIGGANRTDICQGDLGD
CWLLAAIACLTLNERLLFRVIPHDQSFTENYAGIFHFQFWRYGDWVDVVIDDCLPTYNNQLVFT
KSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVTEFFEIKDAPSDMYKIMRKAI
ERGSLMGCSIDDGTNMTYGTSPSGLNMGELIARMVRNMDNSLLRDSDLDPRASDDRPSRTIVPV
QYETRMACGLVKGHAYSVTGLEEALFKGEKVKLVRLRNPWGQVEWNGSWSDGWKDWSFVDKDEK
ARLQHQVTEDGEFWMSYDDFVYHFTKLEICNLTADALESDKLQTWTVSVNEGRWVRGCSAGGCR
NFPDTFWTNPQYRLKLLEEDDDPDDSEVICSFLVALMQKNRRKDRKLGANLFTIGFAIYEVPKE
MHGNKQHLQKDFFLYNASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRVFSE
KRNLSEEAENTISVDRPVKKKKNKPIIFVSDRANSNKELGVDQEAEEGKDKTGPDKQGESPQPR
PGHTDQESEEQQQFRNIFRQIAGDDMEICADELKNVLNTVVNKHKDLKTQGFTLESCRSMIALM
DTDGSGRLNLQEFHHLWKKIKAWQKIFKHYDTDHSGTINSYEMRNAVNDAGFHLNSQLYDIITM
RYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA

hide sequence

RefSeq Acc Id:	XP_006234791 ⟸ XM_006234729
- Peptide Label:	isoform X4
- UniProtKB:	O70482 (UniProtKB/TrEMBL), Q9QZF9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPYLLPGFFCDRVIRERDRRNGEGTVSQPLKFEGQDFVVLKQRCLAQKCLFEDRVFPAGTQALG SHELSQKAKMKAITWKRPKEICENPRFIIGGANRTDICQGDLGDCWFLAAIACLTLNERLLFRV IPHDQSFTENYAGIFHFQFWRYGDWVDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKL HGSYEALKGGNTTEAMEDFTGGVTEFFEIKDAPSDMYKIMRKAIERGSLMGCSIDDGTNMTYGT SPSGLNMGELIARMVRNMDNSLLRDSDLDPRASDDRPSRTIVPVQYETRMACGLVKGHAYSVTG LEEALFKGEKVKLVRLRNPWGQVEWNGSWSDGWKDWSFVDKDEKARLQHQVTEDGEFWMSYDDF VYHFTKLEICNLTADALESDKLQTWTVSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLLEED DDPDDSEVICSFLVALMQKNRRKDRKLGANLFTIGFAIYEVPKEMHGNKQHLQKDFFLYNASKA RSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRVFSEKRNLSEEAENTISVDRPVPR PGHTDQESEEQQQFRNIFRQIAGDDMEICADELKNVLNTVVNKHKDLKTQGFTLESCRSMIALM DTDGSGRLNLQEFHHLWKKIKAWQKIFKHYDTDHSGTINSYEMRNAVNDAGFHLNSQLYDIITM RYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA hide sequence

RefSeq Acc Id:	XP_006234790 ⟸ XM_006234728
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2K9P9 (UniProtKB/TrEMBL), Q9QZF9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPYLLPGFFCDRVIRERDRRNGEGTVSQPLKFEGQDFVVLKQRCLAQKCLFEDRVFPAGTQALG SHELSQKAKMKAITWKRPKEICENPRFIIGGANRTDICQGDLGDCWFLAAIACLTLNERLLFRV IPHDQSFTENYAGIFHFQFWRYGDWVDVVIDDCLPTYNNQLVFTKSNHRNEFWSALLEKAYAKL HGSYEALKGGNTTEAMEDFTGGVTEFFEIKDAPSDMYKIMRKAIERGSLMGCSIDDGTNMTYGT SPSGLNMGELIARMVRNMDNSLLRDSDLDPRASDDRPSRTIVPVQYETRMACGLVKGHAYSVTG LEEALFKGEKVKLVRLRNPWGQVEWNGSWSDGWKDWSFVDKDEKARLQHQVTEDGEFWMSYDDF VYHFTKLEICNLTADALESDKLQTWTVSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLLEED DDPDDSEVICSFLVALMQKNRRKDRKLGANLFTIGFAIYEVPKEMHGNKQHLQKDFFLYNASKA RSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRVFSEKRNLSEEAENTISVDRPVPR PGHTDQESEEQQQFRNIFRQIAGDDMEICADELKNVLNTVVNKRERLAPDVGDGQGPQLSESSS SPFSIPPDKDLKTQGFTLESCRSMIALMDTDGSGRLNLQEFHHLWKKIKAWQKIFKHYDTDHSG TINSYEMRNAVNDAGFHLNSQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGD GIIKLNVLEWLQLTMYA hide sequence

RefSeq Acc Id:	XP_008760303 ⟸ XM_008762081
- Peptide Label:	isoform X2
- UniProtKB:	F1LSQ2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPTVISPTVAPRTGAEPRSPGPVPHPAQGKTTEAGGGHPGGIYSAIISRNFPIIGVKEKTFEQL HKKCLEKKVLYLDPEFPPDETSLFYSQKFPIQFVWKRPPEICENPRFIIGGANRTDICQGDLGD CWFLAAIACLTLNERLLFRVIPHDQSFTENYAGIFHFQFWRYGDWVDVVIDDCLPTYNNQLVFT KSNHRNEFWSALLEKAYAKLHGSYEALKGGNTTEAMEDFTGGVTEFFEIKDAPSDMYKIMRKAI ERGSLMGCSIDDGTNMTYGTSPSGLNMGELIARMVRNMDNSLLRDSDLDPRASDDRPSRTIVPV QYETRMACGLVKGHAYSVTGLEEALFKGEKVKLVRLRNPWGQVEWNGSWSDGWKDWSFVDKDEK ARLQHQVTEDGEFWMSYDDFVYHFTKLEICNLTADALESDKLQTWTVSVNEGRWVRGCSAGGCR NFPDTFWTNPQYRLKLLEEDDDPDDSEVICSFLVALMQKNRRKDRKLGANLFTIGFAIYEVPKE MHGNKQHLQKDFFLYNASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRVFSE KRNLSEEAENTISVDRPVPRPGHTDQESEEQQQFRNIFRQIAGDDMEICADELKNVLNTVVNKH KDLKTQGFTLESCRSMIALMDTDGSGRLNLQEFHHLWKKIKAWQKIFKHYDTDHSGTINSYEMR NAVNDAGFHLNSQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVL EWLQLTMYA hide sequence

RefSeq Acc Id:

ENSRNOP00000075081 ⟸ ENSRNOT00000082876

RefSeq Acc Id:

ENSRNOP00000069651 ⟸ ENSRNOT00000079079

RefSeq Acc Id:

ENSRNOP00000071494 ⟸ ENSRNOT00000080533

RefSeq Acc Id:

ENSRNOP00000011761 ⟸ ENSRNOT00000011761

RefSeq Acc Id:	XP_038960349 ⟸ XM_039104421
- Peptide Label:	isoform X6
- UniProtKB:	A0A8I5ZMW7 (UniProtKB/TrEMBL), F1LSQ2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038960347 ⟸ XM_039104419
- Peptide Label:	isoform X3
- UniProtKB:	P16259 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038960350 ⟸ XM_039104422
- Peptide Label:	isoform X7
- UniProtKB:	O08702 (UniProtKB/TrEMBL), A0A0G2K0L5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038960348 ⟸ XM_039104420
- Peptide Label:	isoform X5
- UniProtKB:	O70376 (UniProtKB/TrEMBL), A0A0G2K0L5 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000080932 ⟸ ENSRNOT00000108270

RefSeq Acc Id:

ENSRNOP00000079180 ⟸ ENSRNOT00000109382

RefSeq Acc Id:

ENSRNOP00000087393 ⟸ ENSRNOT00000115649

Protein Domains

Calpain catalytic EF-hand

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P16259-F1-model_v2	AlphaFold	P16259	1-821	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:2269	AgrOrtholog
BioCyc Gene	G2FUF-48164	BioCyc
Ensembl Genes	ENSRNOG00000008609	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000011761.7	UniProtKB/TrEMBL
	ENSRNOT00000079079.2	UniProtKB/TrEMBL
	ENSRNOT00000080533	ENTREZGENE
	ENSRNOT00000080533.2	UniProtKB/TrEMBL
	ENSRNOT00000082876	ENTREZGENE
	ENSRNOT00000082876.2	UniProtKB/TrEMBL
	ENSRNOT00000108270	ENTREZGENE
	ENSRNOT00000108270.1	UniProtKB/TrEMBL
	ENSRNOT00000109382	ENTREZGENE
	ENSRNOT00000109382.1	UniProtKB/TrEMBL
	ENSRNOT00000115649.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.120.380	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Cysteine proteinases	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	EF-hand	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	C2_III	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Calpain_cysteine_protease	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Calpain_domain_III	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Calpain_III	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Calpain_III_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CAPN3/9	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	EF-hand-dom_pair	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	EF_Hand_1_Ca_BS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	EF_hand_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Papain-like_cys_pep_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Pept_cys_AS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Peptidase_C2_calpain_cat	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:29155	UniProtKB/Swiss-Prot
NCBI Gene	29155	ENTREZGENE
PANTHER	CALPAIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR10183:SF329	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Calpain_III	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Calpain_u2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	EF-hand_8	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Peptidase_C2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Capn3	PhenoGen
PRINTS	CALPAIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	CALPAIN_CAT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	EF_HAND_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	EF_HAND_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	THIOL_PROTEASE_CYS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000008609	RatGTEx
SMART	calpain_III	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CysPc	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	EFh	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF47473	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF49758	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF54001	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0G2JVX0_RAT	UniProtKB/TrEMBL
	A0A0G2K0L5	ENTREZGENE, UniProtKB/TrEMBL
	A0A0G2K9P9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZMW7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZRY1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A336_RAT	UniProtKB/TrEMBL
	A6HPJ0_RAT	UniProtKB/TrEMBL
	A6HPJ1_RAT	UniProtKB/TrEMBL
	A6HPJ2_RAT	UniProtKB/TrEMBL
	A6HPJ3_RAT	UniProtKB/TrEMBL
	A6HPJ4_RAT	UniProtKB/TrEMBL
	A6HPJ7_RAT	UniProtKB/TrEMBL
	A6HPJ8_RAT	UniProtKB/TrEMBL
	CAN3_RAT	UniProtKB/Swiss-Prot
	F1LSQ2	ENTREZGENE, UniProtKB/TrEMBL
	O08702	ENTREZGENE, UniProtKB/TrEMBL
	O70376	ENTREZGENE, UniProtKB/TrEMBL
	O70482	ENTREZGENE, UniProtKB/TrEMBL
	P16259	ENTREZGENE
	Q9QZF9	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2002-06-10	Capn3	calpain 3			Symbol and Name status set to approved	70586	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expressed in the muscle, forebrain, in the corpus callosum and in the dentate gyrus of the brain	634694
gene_expression	p94 isoform expressed only in skeletal muscle, not expressed in heart or in smooth muscle	69795
gene_expression	Lp84 isoform expressed exclusively in lens of eye	1299839
gene_function	calcium-dependent protease	634694
gene_function	Lp82 isoform exhibits calcium-activated protease activity	1299852
gene_process	may be involved in astrocyte plasticity and/or motility	634694
gene_process	Lp82 isoform may contribute to proteolysis of lens crystallin proteins in both normal development and in cataract formation	1299852
gene_transcript	alternatively spliced into p94 or Lp82 isoforms via usage of alternative exon 1 and deletions of IS1 and IS2 regions	1299839

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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