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Gene: Gcg (glucagon) Rattus norvegicus
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Symbol: Gcg
Name: glucagon
Description: Exhibits glucagon receptor binding activity and hormone activity. Involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway; negative regulation of appetite; and response to L-arginine. Localizes to the extracellular space. Human ortholog(s) of this gene implicated in Alzheimer's disease and prediabetes syndrome. Orthologous to human GCG (glucagon); PARTICIPATES IN forkhead class A signaling pathway; glucagon signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 3',5'-cyclic AMP; 3-isobutyl-1-methyl-7H-xanthine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GLP-1; glucagon-like peptide-1
Orthologs:
Homo sapiens (human) : GCG (glucagon)  HGNC  Alliance
Mus musculus (house mouse) : Gcg (glucagon)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gcg (glucagon)
Pan paniscus (bonobo/pygmy chimpanzee) : GCG (glucagon)
Canis lupus familiaris (dog) : GCG (glucagon)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gcg (glucagon)
Sus scrofa (pig) : GCG (glucagon)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0348,442,635 - 48,451,650 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0355,108,272 - 55,117,287 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4344,433,180 - 44,438,004 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1344,329,550 - 44,334,376 (-)NCBI
Celera346,755,241 - 46,764,256 (-)NCBICelera
Cytogenetic Map3q21NCBI
RH 3.4 Map3602.83RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gcg
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2668
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-09-17
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.