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Gene: Cacnb4 (calcium voltage-gated channel auxiliary subunit beta 4) Rattus norvegicus
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Symbol: Cacnb4
Name: calcium voltage-gated channel auxiliary subunit beta 4
Description: Exhibits protein kinase binding activity and voltage-gated calcium channel activity. Involved in several processes, including negative regulation of G1/S transition of mitotic cell cycle; positive regulation of protein localization to nucleolus; and positive regulation of voltage-gated calcium channel activity. Localizes to the cytoplasm; nucleus; and presynapse. Human ortholog(s) of this gene implicated in dilated cardiomyopathy; episodic ataxia; episodic ataxia type 5; and idiopathic generalized epilepsy. Orthologous to human CACNB4 (calcium voltage-gated channel auxiliary subunit beta 4); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; arrhythmogenic right ventricular cardiomyopathy pathway; INTERACTS WITH (RS)-amphetamine; 17beta-estradiol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CAB4; calcium channel beta 4 subunit; calcium channel voltage-dependent beta 4 subunit; calcium channel voltage-dependent subunit beta 4; calcium channel, voltage-dependent, beta 4 subunit; voltage-dependent L-type calcium channel subunit beta-4
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0337,950,846 - 38,211,478 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0343,050,530 - 43,312,292 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4333,934,478 - 34,072,070 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1333,830,849 - 34,089,967 (-)NCBI
Celera335,052,892 - 35,186,998 (-)NCBICelera
Cytogenetic Map3q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cacnb4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68385
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.