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Gene: Grb14 (growth factor receptor bound protein 14) Rattus norvegicus
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Symbol: Grb14
Name: growth factor receptor bound protein 14
Description: Exhibits phosphoprotein binding activity. Involved in several processes, including insulin receptor signaling pathway; negative regulation of insulin receptor signaling pathway; and negative regulation of meiotic cell cycle process involved in oocyte maturation. Localizes to the Golgi apparatus; endosome; and plasma membrane. Orthologous to human GRB14 (growth factor receptor bound protein 14); PARTICIPATES IN insulin signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: GRB14 adapter protein; growth factor receptor-bound protein 14
Orthologs:
Homo sapiens (human) : GRB14 (growth factor receptor bound protein 14)  HGNC  Alliance
Mus musculus (house mouse) : Grb14 (growth factor receptor bound protein 14)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grb14 (growth factor receptor bound protein 14)
Pan paniscus (bonobo/pygmy chimpanzee) : GRB14 (growth factor receptor bound protein 14)
Canis lupus familiaris (dog) : GRB14 (growth factor receptor bound protein 14)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grb14 (growth factor receptor bound protein 14)
Sus scrofa (pig) : GRB14 (growth factor receptor bound protein 14)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0350,937,403 - 51,054,447 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl350,937,669 - 51,054,378 (-)Ensembl
Rnor_5.0357,578,226 - 57,619,404 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0357,679,758 - 57,695,025 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4346,832,380 - 46,952,670 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1346,728,757 - 46,849,042 (-)NCBI
Celera349,175,830 - 49,290,450 (-)NCBICelera
Cytogenetic Map3q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Grb14
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61869
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.