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Gene: GRB14 (growth factor receptor bound protein 14) Homo sapiens
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Symbol: GRB14
Name: growth factor receptor bound protein 14
Description: Exhibits protein homodimerization activity and receptor tyrosine kinase binding activity. Involved in negative regulation of insulin receptor signaling pathway. Localizes to the cytoplasm; intracellular membrane-bounded organelle; and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: GRB14 adapter protein; growth factor receptor-bound protein 14
Orthologs:
Mus musculus (house mouse) : Grb14 (growth factor receptor bound protein 14)  MGI  Alliance
Rattus norvegicus (Norway rat) : Grb14 (growth factor receptor bound protein 14)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grb14 (growth factor receptor bound protein 14)
Pan paniscus (bonobo/pygmy chimpanzee) : GRB14 (growth factor receptor bound protein 14)
Canis lupus familiaris (dog) : GRB14 (growth factor receptor bound protein 14)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grb14 (growth factor receptor bound protein 14)
Sus scrofa (pig) : GRB14 (growth factor receptor bound protein 14)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382164,492,417 - 164,622,959 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372165,349,323 - 165,478,360 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362165,057,569 - 165,186,606 (-)NCBINCBI36hg18NCBI36
Build 342165,174,839 - 165,303,865NCBI
Celera2158,959,227 - 159,088,293 (-)NCBI
Cytogenetic Map2q24.3NCBI
HuRef2157,231,772 - 157,360,824 (-)NCBIHuRef
CHM1_12165,354,810 - 165,484,258 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on GRB14
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732013
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.