GRB14 (growth factor receptor bound protein 14) - Rat Genome Database

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Gene: GRB14 (growth factor receptor bound protein 14) Sus scrofa
Analyze
Symbol: GRB14
Name: growth factor receptor bound protein 14
RGD ID: 14126311
Description: ENCODES a protein that exhibits phosphoprotein binding (ortholog); INVOLVED IN cellular response to insulin stimulus (ortholog); insulin receptor signaling pathway (ortholog); intracellular signal transduction (ortholog); PARTICIPATES IN insulin signaling pathway; ASSOCIATED WITH type 2 diabetes mellitus (ortholog); Weight Gain (ortholog); FOUND IN cytoplasm (ortholog); endosome (ortholog); Golgi apparatus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: growth factor receptor-bound protein 14
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1571,119,926 - 71,247,393 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11571,119,928 - 71,247,426 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21579,273,968 - 79,340,255 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
GRB14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1571,119,926 - 71,247,393 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11571,119,928 - 71,247,426 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21579,273,968 - 79,340,255 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GRB14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2164,492,417 - 164,621,482 (-)EnsemblGRCh38hg38GRCh38
GRCh382164,492,417 - 164,622,959 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372165,348,927 - 165,477,992 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362165,057,569 - 165,186,606 (-)NCBINCBI36hg18NCBI36
Build 342165,174,839 - 165,303,865NCBI
Celera2158,959,227 - 159,088,293 (-)NCBI
Cytogenetic Map2q24.3NCBI
HuRef2157,231,772 - 157,360,824 (-)NCBIHuRef
CHM1_12165,355,217 - 165,484,258 (-)NCBICHM1_1
Grb14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39264,742,820 - 64,853,354 (-)NCBIGRCm39mm39
GRCm39 Ensembl264,742,820 - 64,855,331 (-)Ensembl
GRCm38264,912,476 - 65,022,766 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl264,912,476 - 65,024,987 (-)EnsemblGRCm38mm10GRCm38
MGSCv37264,750,535 - 64,860,823 (-)NCBIGRCm37mm9NCBIm37
MGSCv36264,713,317 - 64,823,605 (-)NCBImm8
Celera266,583,155 - 66,693,422 (-)NCBICelera
Cytogenetic Map2C1.3NCBI
Grb14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2349,568,210 - 49,683,805 (-)NCBI
Rnor_6.0 Ensembl350,937,669 - 51,054,378 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0350,937,403 - 51,054,447 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0357,679,758 - 57,695,025 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0357,578,226 - 57,619,404 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4346,832,380 - 46,952,670 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1346,728,757 - 46,849,042 (-)NCBI
Celera349,175,830 - 49,290,450 (-)NCBICelera
Cytogenetic Map3q21NCBI
Grb14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554499,466,706 - 9,591,598 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554499,466,764 - 9,589,559 (+)NCBIChiLan1.0ChiLan1.0
GRB14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B169,135,019 - 169,262,834 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B169,135,231 - 169,263,874 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B51,773,844 - 51,902,420 (-)NCBIMhudiblu_PPA_v0panPan3
GRB14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1369,711,885 - 9,843,266 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl369,712,142 - 9,721,769 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha369,856,214 - 9,987,580 (-)NCBI
ROS_Cfam_1.0369,844,049 - 9,975,461 (-)NCBI
UMICH_Zoey_3.1369,855,062 - 9,986,361 (-)NCBI
UNSW_CanFamBas_1.0369,897,060 - 10,011,627 (-)NCBI
UU_Cfam_GSD_1.03610,011,150 - 10,142,536 (-)NCBI
Grb14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303126,875,121 - 126,989,222 (-)NCBI
SpeTri2.0NW_00493646914,628,478 - 14,742,327 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GRB14
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11049,952,835 - 50,085,274 (-)NCBI
ChlSab1.1 Ensembl1049,953,059 - 50,084,869 (-)Ensembl
Vero_WHO_p1.0NW_023666040149,415,172 - 149,544,225 (+)NCBI
Grb14
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624732811,486 - 949,972 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 1 2
Low 5 3 3 5 2 21 3 1
Below cutoff 4 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000017314   ⟹   ENSSSCP00000016851
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1571,120,194 - 71,186,447 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000041677   ⟹   ENSSSCP00000052265
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1571,119,926 - 71,247,384 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000046043   ⟹   ENSSSCP00000053994
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1571,120,194 - 71,247,393 (-)Ensembl
RefSeq Acc Id: XM_013984198   ⟹   XP_013839652
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11571,119,928 - 71,186,472 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021075426   ⟹   XP_020931085
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11571,119,928 - 71,247,425 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021075427   ⟹   XP_020931086
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11571,119,928 - 71,247,426 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021075428   ⟹   XP_020931087
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11571,119,928 - 71,247,425 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013839652 (Get FASTA)   NCBI Sequence Viewer  
  XP_020931085 (Get FASTA)   NCBI Sequence Viewer  
  XP_020931086 (Get FASTA)   NCBI Sequence Viewer  
  XP_020931087 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020931086   ⟸   XM_021075427
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_020931087   ⟸   XM_021075428
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_020931085   ⟸   XM_021075426
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013839652   ⟸   XM_013984198
- Peptide Label: isoform X4
- UniProtKB: F1RPN5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000052265   ⟸   ENSSSCT00000041677
RefSeq Acc Id: ENSSSCP00000016851   ⟸   ENSSSCT00000017314
RefSeq Acc Id: ENSSSCP00000053994   ⟸   ENSSSCT00000046043
Protein Domains
PH   Ras-associating   SH2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000015901 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070025435 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000016851 UniProtKB/TrEMBL
  ENSSSCP00000052265 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000053994 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070042982 UniProtKB/TrEMBL
  ENSSSCP00070042984 UniProtKB/TrEMBL
  ENSSSCP00070042987 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000017314 UniProtKB/TrEMBL
  ENSSSCT00000041677 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000046043 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070050845 UniProtKB/TrEMBL
  ENSSSCT00070050846 UniProtKB/TrEMBL
  ENSSSCT00070050849 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  3.30.505.10 UniProtKB/TrEMBL
InterPro BPS-dom UniProtKB/TrEMBL
  GRB/APBB1IP UniProtKB/TrEMBL
  Grb14 UniProtKB/TrEMBL
  Grb14_SH2 UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_APBB1IP UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  RA_dom UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
KEGG Report ssc:100514075 UniProtKB/TrEMBL
NCBI Gene GRB14 ENTREZGENE
PANTHER PTHR11243 UniProtKB/TrEMBL
  PTHR11243:SF22 UniProtKB/TrEMBL
Pfam BPS UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
  PF00788 UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
PRINTS SH2DOMAIN UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
  PS50200 UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
SMART SH2 UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
  SM00314 UniProtKB/TrEMBL
Superfamily-SCOP SSF54236 UniProtKB/TrEMBL
  SSF55550 UniProtKB/TrEMBL
UniProt A0A287B7H4_PIG UniProtKB/TrEMBL
  A0A287BCB8_PIG UniProtKB/TrEMBL
  A0A480SVQ1_PIG UniProtKB/TrEMBL
  A0A4X1VLU8_PIG UniProtKB/TrEMBL
  A0A4X1VMD2_PIG UniProtKB/TrEMBL
  A0A4X1VMD7_PIG UniProtKB/TrEMBL
  F1RPN5 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:96336 ENTREZGENE