Gene: Scn3a (sodium voltage-gated channel alpha subunit 3) Rattus norvegicus
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Symbol: Scn3a
Name: sodium voltage-gated channel alpha subunit 3
Description: ENCODES a protein that exhibits calmodulin binding; sodium ion binding; voltage-gated sodium channel activity; INVOLVED IN cellular response to antibiotic; nervous system development; neuronal action potential; ASSOCIATED WITH Spinal Cord Injuries; benign neonatal seizures (ortholog); complex partial epilepsy (ortholog); FOUND IN axon; neuronal cell body; voltage-gated sodium channel complex; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil
AGR Description: Exhibits calmodulin binding activity, sodium ion binding activity, and voltage-gated sodium channel activity; involved in several processes, including cellular response to antibiotic, nervous system development, and neuronal action potential; localizes to the axon, neuronal cell body, and voltage-gated sodium channel complex; orthologous to human SCN3A (sodium voltage-gated channel alpha subunit 3).
Merged Description: Exhibits calmodulin binding activity, sodium ion binding activity, and voltage-gated sodium channel activity; involved in several processes, including cellular response to antibiotic, nervous system development, and neuronal action potential; localizes to the axon, neuronal cell body, and voltage-gated sodium channel complex; orthologous to human SCN3A (sodium voltage-gated channel alpha subunit 3); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC100360249; Nav1.3; rCG26412-like; SCIII; Scn2a; sodium channel protein brain III subunit alpha; sodium channel protein type 3 subunit alpha; sodium channel protein type 3 subunit alpha-like; sodium channel protein type III subunit alpha; sodium channel protein, brain III subunit alpha; sodium channel, voltage-gated, type 3, alpha subunit; sodium channel, voltage-gated, type III, alpha; sodium channel, voltage-gated, type III, alpha polypeptide; sodium channel, voltage-gated, type III, alpha subunit; voltage-gated sodium channel subtype III; voltage-gated sodium channel subunit alpha Nav1.3
Orthologs:
Homo sapiens (human) : SCN3A (sodium voltage-gated channel alpha subunit 3)  HGNC  Alliance
Mus musculus (house mouse) : Scn3a (sodium channel, voltage-gated, type III, alpha)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Scn3a (sodium voltage-gated channel alpha subunit 3)
Pan paniscus (bonobo/pygmy chimpanzee) : SCN3A (sodium voltage-gated channel alpha subunit 3)
Canis lupus familiaris (dog) : SCN3A (sodium voltage-gated channel alpha subunit 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Scn3a (sodium voltage-gated channel alpha subunit 3)
Sus scrofa (pig) : SCN3A (sodium voltage-gated channel alpha subunit 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0351,530,897 - 51,643,140 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0358,165,763 - 58,277,870 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4347,501,895 - 47,512,863NCBIRGSC3.4rn4RGSC3.4
Celera349,742,093 - 49,851,946 (-)NCBICelera
Cytogenetic Map3q21NCBI
RH 3.4 Map3 RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Scn3a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3635
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.