Scn3a (sodium voltage-gated channel alpha subunit 3) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Scn3a (sodium voltage-gated channel alpha subunit 3) Ictidomys tridecemlineatus
Analyze
Symbol: Scn3a
Name: sodium voltage-gated channel alpha subunit 3
RGD ID: 12578732
Description: ENCODES a protein that exhibits calmodulin binding (ortholog); sodium ion binding (ortholog); voltage-gated sodium channel activity (ortholog); INVOLVED IN cellular response to antibiotic (ortholog); nervous system development (ortholog); neuronal action potential (ortholog); ASSOCIATED WITH asphyxiating thoracic dystrophy (ortholog); asphyxiating thoracic dystrophy 1 (ortholog); benign familial infantile seizures 3 (ortholog); FOUND IN axon (ortholog); neuronal cell body (ortholog); voltage-gated sodium channel complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sodium channel protein type 3 subunit alpha; sodium channel, voltage-gated, type III, alpha subunit; sodium voltage-gated channel alpha subunit 3, transcript variant X1; sodium voltage-gated channel alpha subunit 3, transcript variant X2; sodium voltage-gated channel alpha subunit 3, transcript variant X3; sodium voltage-gated channel alpha subunit 3, transcript variant X4; sodium voltage-gated channel alpha subunit 3, transcript variant X5; sodium voltage-gated channel alpha subunit 3, transcript variant X6; sodium voltage-gated channel alpha subunit 3, transcript variant X7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303127,437,094 - 127,545,534 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646914,101,868 - 14,179,998 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646914,072,182 - 14,180,552 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Scn3a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303127,437,094 - 127,545,534 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646914,101,868 - 14,179,998 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646914,072,182 - 14,180,552 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SCN3A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382165,087,526 - 165,204,050 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2165,087,526 - 165,204,050 (-)EnsemblGRCh38hg38GRCh38
GRCh372165,944,036 - 166,060,560 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362165,652,276 - 165,768,823 (-)NCBINCBI36Build 36hg18NCBI36
Build 342165,769,546 - 165,886,060NCBI
Celera2159,554,632 - 159,671,179 (-)NCBICelera
Cytogenetic Map2q24.3NCBI
HuRef2157,826,522 - 157,942,999 (-)NCBIHuRef
CHM1_12165,949,962 - 166,066,539 (-)NCBICHM1_1
T2T-CHM13v2.02165,544,858 - 165,661,382 (-)NCBIT2T-CHM13v2.0
Scn3a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39265,287,462 - 65,397,935 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl265,288,607 - 65,397,971 (-)EnsemblGRCm39 Ensembl
GRCm38265,457,118 - 65,567,591 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl265,457,118 - 65,567,627 (-)EnsemblGRCm38mm10GRCm38
MGSCv37265,295,175 - 65,405,549 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36265,260,704 - 65,368,333 (-)NCBIMGSCv36mm8
Celera267,134,509 - 67,244,961 (-)NCBICelera
Cytogenetic Map2C1.3NCBI
cM Map238.55NCBI
Scn3a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8370,554,496 - 70,666,198 (-)NCBIGRCr8
mRatBN7.2350,146,411 - 50,258,119 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl350,148,139 - 50,258,119 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx353,491,661 - 53,601,660 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0362,075,268 - 62,185,269 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0359,858,870 - 59,968,781 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0351,530,897 - 51,643,140 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl351,532,627 - 51,643,140 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0358,165,763 - 58,277,870 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4347,501,895 - 47,512,863NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera349,742,093 - 49,851,946 (-)NCBICelera
RH 3.4 Map3 RGD
Cytogenetic Map3q21NCBI
Scn3a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554498,896,454 - 9,009,304 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554498,896,454 - 9,009,304 (+)NCBIChiLan1.0ChiLan1.0
SCN3A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21367,748,846 - 67,865,733 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B67,763,601 - 67,880,709 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B52,363,020 - 52,479,818 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B169,722,134 - 169,838,590 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B169,722,134 - 169,838,590 (-)Ensemblpanpan1.1panPan2
SCN3A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13610,300,091 - 10,405,361 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3610,302,191 - 10,377,923 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3610,443,366 - 10,548,111 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03610,431,868 - 10,536,904 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3610,431,875 - 10,536,895 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13610,504,943 - 10,609,699 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03610,485,818 - 10,590,745 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03610,598,953 - 10,703,719 (-)NCBIUU_Cfam_GSD_1.0
SCN3A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1571,717,334 - 71,824,160 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11571,717,330 - 71,824,190 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21580,183,966 - 80,256,583 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SCN3A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11050,563,560 - 50,679,179 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1050,563,568 - 50,637,179 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040148,830,543 - 148,945,804 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Scn3a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624732251,860 - 328,917 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624732222,657 - 330,959 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSSTOT00000014181   ⟹   ENSSTOP00000012705
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493646914,101,868 - 14,179,998 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000037276   ⟹   ENSSTOP00000031805
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493646914,101,868 - 14,179,998 (+)Ensembl
RefSeq Acc Id: XM_005315716   ⟹   XP_005315773
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303127,437,094 - 127,545,534 (-)NCBI
SpeTri2.0NW_00493646914,072,182 - 14,180,552 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005315717   ⟹   XP_005315774
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303127,437,094 - 127,545,534 (-)NCBI
SpeTri2.0NW_00493646914,072,182 - 14,180,552 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005315720   ⟹   XP_005315777
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303127,437,094 - 127,545,534 (-)NCBI
SpeTri2.0NW_00493646914,072,182 - 14,180,552 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005315721   ⟹   XP_005315778
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303127,437,094 - 127,545,534 (-)NCBI
SpeTri2.0NW_00493646914,072,182 - 14,180,552 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021728551   ⟹   XP_021584226
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303127,437,094 - 127,545,534 (-)NCBI
SpeTri2.0NW_00493646914,072,182 - 14,180,552 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021728584   ⟹   XP_021584259
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303127,437,094 - 127,545,534 (-)NCBI
SpeTri2.0NW_00493646914,072,182 - 14,180,552 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040294404   ⟹   XP_040150338
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303127,437,094 - 127,545,534 (-)NCBI
RefSeq Acc Id: XM_040294405   ⟹   XP_040150339
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303127,437,094 - 127,515,861 (-)NCBI
RefSeq Acc Id: XM_040294406   ⟹   XP_040150340
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303127,437,094 - 127,480,441 (-)NCBI
RefSeq Acc Id: XP_005315774   ⟸   XM_005315717
- Peptide Label: isoform X2
- UniProtKB: A0A287DE16 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005315778   ⟸   XM_005315721
- Peptide Label: isoform X7
- UniProtKB: I3MMF3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005315773   ⟸   XM_005315716
- Peptide Label: isoform X1
- UniProtKB: A0A287DE16 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005315777   ⟸   XM_005315720
- Peptide Label: isoform X6
- UniProtKB: I3MMF3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021584226   ⟸   XM_021728551
- Peptide Label: isoform X3
- UniProtKB: A0A287DE16 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021584259   ⟸   XM_021728584
- Peptide Label: isoform X4
- UniProtKB: I3MMF3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040150338   ⟸   XM_040294404
- Peptide Label: isoform X5
- UniProtKB: I3MMF3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040150339   ⟸   XM_040294405
- Peptide Label: isoform X8
- UniProtKB: A0A287DE16 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040150340   ⟸   XM_040294406
- Peptide Label: isoform X9
RefSeq Acc Id: ENSSTOP00000012705   ⟸   ENSSTOT00000014181
RefSeq Acc Id: ENSSTOP00000031805   ⟸   ENSSTOT00000037276

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000014168 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000014181.3 UniProtKB/TrEMBL
  ENSSTOT00000037276.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.70 UniProtKB/TrEMBL
  1.20.120.350 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
  iswi atpase UniProtKB/TrEMBL
InterPro Ion_trans_dom UniProtKB/TrEMBL
  IQ_motif_EF-hand-BS UniProtKB/TrEMBL
  Na_channel_asu UniProtKB/TrEMBL
  Na_chnl_inactivation_gate UniProtKB/TrEMBL
  Na_trans_assoc UniProtKB/TrEMBL
  Na_trans_cytopl UniProtKB/TrEMBL
  VGCC_Ca_Na UniProtKB/TrEMBL
  Volt_channel_dom_sf UniProtKB/TrEMBL
NCBI Gene Scn3a ENTREZGENE
PANTHER PTHR10037 UniProtKB/TrEMBL
  SODIUM CHANNEL PROTEIN TYPE 3 SUBUNIT ALPHA UniProtKB/TrEMBL
Pfam Ion_trans UniProtKB/TrEMBL
  Na_trans_assoc UniProtKB/TrEMBL
  Na_trans_cytopl UniProtKB/TrEMBL
PRINTS NACHANNEL UniProtKB/TrEMBL
PROSITE PS50096 UniProtKB/TrEMBL
Superfamily-SCOP Voltage-gated potassium channels UniProtKB/TrEMBL
UniProt A0A287DE16 ENTREZGENE, UniProtKB/TrEMBL
  I3MMF3 ENTREZGENE, UniProtKB/TrEMBL