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Gene: Acvr2a (activin A receptor type 2A) Rattus norvegicus
Symbol: Acvr2a
Name: activin A receptor type 2A
RGD ID: 70911
Description: Exhibits activin binding activity and inhibin binding activity. Involved in adrenal gland development; positive regulation of follicle-stimulating hormone secretion; and response to organic substance. Predicted to localize to several cellular components, including activin receptor complex; cell surface; and inhibin-betaglycan-ActRII complex. Human ortholog(s) of this gene implicated in colon cancer. Orthologous to human ACVR2A (activin A receptor type 2A); PARTICIPATES IN activin signaling pathway; cytokine mediated signaling pathway; transforming growth factor-beta superfamily mediated signaling pathway; INTERACTS WITH 6-propyl-2-thiouracil; acetamide; ammonium chloride.
Type: protein-coding
Also known as: activin A receptor, type IIA; activin receptor IIA; activin receptor type IIA; activin receptor type-2A; ACTR-IIA; Acvr2; rActR-II; type II activin receptor
Homo sapiens (human) : ACVR2A (activin A receptor type 2A)  HGNC  Alliance
Mus musculus (house mouse) : Acvr2a (activin receptor IIA)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acvr2a (activin A receptor type 2A)
Pan paniscus (bonobo/pygmy chimpanzee) : ACVR2A (activin A receptor type 2A)
Canis lupus familiaris (dog) : ACVR2A (activin A receptor type 2A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acvr2a (activin A receptor type 2A)
Sus scrofa (pig) : ACVR2A (activin A receptor type 2A)
Chlorocebus sabaeus (African green monkey) : ACVR2A (activin A receptor type 2A)
Heterocephalus glaber (naked mole-rat) : Acvr2a (activin A receptor type 2A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0332,947,901 - 33,034,598 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl332,947,378 - 33,034,282 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0338,113,728 - 38,197,531 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4329,779,827 - 29,808,881 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1329,676,198 - 29,705,253 (+)NCBI
Celera331,412,348 - 31,490,813 (+)NCBICelera
Cytogenetic Map3q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Acvr2a
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70911
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.