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Gene: Ifih1 (interferon induced with helicase C domain 1) Rattus norvegicus
Symbol: Ifih1
Name: interferon induced with helicase C domain 1
RGD ID: 1560496
Description: Predicted to have several functions, including RNA binding activity; identical protein binding activity; and zinc ion binding activity. Predicted to be involved in several processes, including cellular response to exogenous dsRNA; positive regulation of cytokine production; and protein sumoylation. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome. Orthologous to human IFIH1 (interferon induced with helicase C domain 1); PARTICIPATES IN influenza A pathway; measles pathway; Retinoic acid-inducible gene (RIG) I-like receptor signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
Also known as: interferon-induced helicase C domain-containing protein 1; LOC499801; RGD1560496; similar to HELICARD
Homo sapiens (human) : IFIH1 (interferon induced with helicase C domain 1)  HGNC  Alliance
Mus musculus (house mouse) : Ifih1 (interferon induced with helicase C domain 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ifih1 (interferon induced with helicase C domain 1)
Pan paniscus (bonobo/pygmy chimpanzee) : IFIH1 (interferon induced with helicase C domain 1)
Canis lupus familiaris (dog) : IFIH1 (interferon induced with helicase C domain 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ifih1 (interferon induced with helicase C domain 1)
Sus scrofa (pig) : IFIH1 (interferon induced with helicase C domain 1)
Chlorocebus sabaeus (African green monkey) : IFIH1 (interferon induced with helicase C domain 1)
Heterocephalus glaber (naked mole-rat) : Ifih1 (interferon induced with helicase C domain 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0348,557,696 - 48,604,097 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl348,557,696 - 48,604,097 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0355,221,682 - 55,269,581 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4344,547,092 - 44,593,969 (-)NCBIRGSC3.4rn4RGSC3.4
Celera346,870,143 - 46,916,330 (-)NCBICelera
Cytogenetic Map3q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Ifih1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1560496
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.