Itgb6 (integrin subunit beta 6) - Rat Genome Database

Name: Itgb6
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Itgb6 (integrin subunit beta 6) Rattus norvegicus

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Symbol:

Itgb6

Name:

integrin subunit beta 6

RGD ID:

1303119

Description:

Predicted to enable integrin binding activity and molecular function activator activity. Predicted to be involved in several processes, including cell adhesion mediated by integrin; integrin-mediated signaling pathway; and transforming growth factor beta production. Predicted to act upstream of or within several processes, including Langerhans cell differentiation; enamel mineralization; and lung development. Predicted to be located in several cellular components, including centrosome; external side of plasma membrane; and nucleoplasm. Predicted to be part of integrin alphav-beta6 complex. Predicted to be active in cell surface and focal adhesion. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 1H. Orthologous to human ITGB6 (integrin subunit beta 6); PARTICIPATES IN integrin mediated signaling pathway; arrhythmogenic right ventricular cardiomyopathy pathway; cell-extracellular matrix signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

integrin beta 6; integrin beta-6; integrin, beta 6; MGC94023

RGD Orthologs

Alliance Orthologs

More Info

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More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ITGB6 (integrin subunit beta 6)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Itgb6 (integrin beta 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Itgb6 (integrin subunit beta 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ITGB6 (integrin subunit beta 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ITGB6 (integrin subunit beta 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Itgb6 (integrin subunit beta 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ITGB6 (integrin subunit beta 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ITGB6 (integrin subunit beta 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Itgb6 (integrin subunit beta 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ITGB6 (integrin subunit beta 6)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Itgb6 (integrin beta 6)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	itgb6 (integrin, beta 6)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	pat-3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	mys	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoInspector\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	itgb6	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	65,454,964 - 65,579,179 (-)	NCBI		GRCr8
mRatBN7.2	3	45,046,295 - 45,170,532 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	45,048,044 - 45,121,671 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	48,404,699 - 48,477,782 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	56,988,255 - 57,061,340 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	54,757,778 - 54,831,418 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	46,652,624 - 46,775,362 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	46,652,623 - 46,726,958 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	51,760,871 - 51,883,770 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	42,286,140 - 42,360,793 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	42,182,533 - 42,257,165 (-)	NCBI
Celera	3	44,745,206 - 44,817,710 (-)	NCBI		Celera
Cytogenetic Map	3	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

amelogenesis imperfecta type 1H (ISO)

asthma (ISS)

autistic disorder (ISO)

autoimmune disease (ISO)

cholangitis (ISO)

Chronic Hepatitis C (ISO)

Experimental Liver Cirrhosis (IMP,ISO)

genetic disease (ISO)

liver cirrhosis (ISO)

liver disease (ISO)

microcephaly (ISO)

prostate cancer (ISO)

pulmonary emphysema (ISO,ISS)

Spontaneous Abortions (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (ISO)

17alpha-ethynylestradiol (EXP,ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-palmitoylglycerol (ISO)

3,4-methylenedioxymethamphetamine (ISO)

3-chloropropane-1,2-diol (EXP)

4,4'-sulfonyldiphenol (EXP,ISO)

4-hydroxynon-2-enal (ISO)

6-propyl-2-thiouracil (EXP)

7,12-dimethyltetraphene (EXP)

aflatoxin B1 (EXP,ISO)

alpha-Zearalanol (EXP)

amitriptyline (EXP)

aristolochic acid A (ISO)

benzo[a]pyrene (EXP,ISO)

Benzo[k]fluoranthene (ISO)

beta-naphthoflavone (EXP)

bexarotene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP,ISO)

bortezomib (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

calcitriol (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chloroprene (ISO)

choline (ISO)

cisplatin (ISO)

cobalt dichloride (EXP)

cocaine (ISO)

copper atom (EXP,ISO)

copper(0) (EXP,ISO)

Cuprizon (EXP)

cycloheximide (ISO)

cyclosporin A (ISO)

cypermethrin (EXP)

DDE (ISO)

dextran sulfate (ISO)

dibutyl phthalate (ISO)

dimethylarsinic acid (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

folic acid (ISO)

furan (EXP)

gemcitabine (ISO)

genistein (ISO)

gentamycin (EXP)

glyphosate (ISO)

hydrogen peroxide (ISO)

Indeno[1,2,3-cd]pyrene (ISO)

indole-3-methanol (EXP)

L-methionine (ISO)

manganese(II) chloride (EXP,ISO)

mercury dibromide (ISO)

methimazole (EXP)

N-methyl-4-phenylpyridinium (EXP)

N-nitrosodiethylamine (EXP)

nickel atom (ISO)

ozone (ISO)

paclitaxel (ISO)

paracetamol (EXP)

paraquat (EXP)

perfluorooctanoic acid (EXP,ISO)

permethrin (ISO)

phenobarbital (EXP)

phenylmercury acetate (ISO)

phorbol 13-acetate 12-myristate (ISO)

pirinixic acid (ISO)

pravastatin (ISO)

progesterone (ISO)

SB 203580 (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sucrose (EXP)

tert-butyl hydroperoxide (ISO)

testosterone (ISO)

tetrachloromethane (ISO)

tetrathiomolybdate(2-) (EXP)

Theaflavin 3,3'-digallate (ISO)

thioacetamide (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

triptonide (ISO)

valproic acid (ISO)

vinclozolin (EXP)

zaragozic acid A (EXP,ISO)

zinc atom (ISO)

zinc dichloride (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

bone development (ISO)

bronchiole development (ISO)

cell adhesion mediated by integrin (ISO,ISS)

cell morphogenesis (ISO)

cell-cell adhesion (IBA)

cell-matrix adhesion (ISO)

cellular response to ionizing radiation (ISO)

enamel mineralization (ISO)

gene expression (ISO)

hard palate development (ISO)

immune response (ISO)

inflammatory response (ISO)

integrin-mediated signaling pathway (IBA)

Langerhans cell differentiation (ISO)

lung alveolus development (ISO)

phospholipid homeostasis (ISO)

response to virus (ISO)

response to wounding (ISO)

skin development (ISO)

surfactant homeostasis (ISO)

transforming growth factor beta production (ISO)

transforming growth factor beta receptor signaling pathway (ISO)

wound healing (ISO)

Cellular Component

cell junction (ISO)

cell surface (IBA,ISO)

centrosome (IEA,ISO)

external side of plasma membrane (ISO)

focal adhesion (IBA,ISO,ISS)

integrin alphav-beta6 complex (IBA,ISO,ISS)

nucleoplasm (IEA,ISO)

receptor complex (ISO)

Molecular Function

integrin binding (IBA,ISO)

metal ion binding (IEA)

molecular function activator activity (ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

arrhythmogenic right ventricular cardiomyopathy pathway (IEA)

cell-extracellular matrix signaling pathway (IEA)

dilated cardiomyopathy pathway (IEA)

hypertrophic cardiomyopathy pathway (IEA)

integrin mediated signaling pathway (ISO,ISS)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Integrins: bidirectional, allosteric signaling machines.	Hynes RO Cell 2002 Sep 20;110(6):673-87.
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	Loss of integrin alpha(v)beta6-mediated TGF-beta activation causes Mmp12-dependent emphysema.	Morris DG, etal., Nature 2003 Mar 13;422(6928):169-73.
5.	Inhibition of integrin alphavbeta6 on cholangiocytes blocks transforming growth factor-beta activation and retards biliary fibrosis progression.	Patsenker E, etal., Gastroenterology. 2008 Aug;135(2):660-70. Epub 2008 Apr 16.
6.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
7.	Integrin alphavbeta6 is a marker of the progression of biliary and portal liver fibrosis and a novel target for antifibrotic therapies.	Popov Y, etal., J Hepatol. 2008 Mar;48(3):453-64. Epub 2008 Jan 14.
8.	GOA pipeline	RGD automated data pipeline
9.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
11.	Comprehensive gene review and curation	RGD comprehensive gene curation
12.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
13.	The integrins.	Takada Y, etal., Genome Biol. 2007;8(5):215.

Additional References at PubMed

PMID:8601592	PMID:9553049	PMID:15489334	PMID:15963261	PMID:17158881	PMID:22278742	PMID:22885106	PMID:23376485	PMID:23382219	PMID:23422496	PMID:24681597	PMID:26279426
PMID:36307995

Genomics

Comparative Map Data

Itgb6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	65,454,964 - 65,579,179 (-)	NCBI		GRCr8
mRatBN7.2	3	45,046,295 - 45,170,532 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	45,048,044 - 45,121,671 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	48,404,699 - 48,477,782 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	56,988,255 - 57,061,340 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	54,757,778 - 54,831,418 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	46,652,624 - 46,775,362 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	46,652,623 - 46,726,958 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	51,760,871 - 51,883,770 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	42,286,140 - 42,360,793 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	42,182,533 - 42,257,165 (-)	NCBI
Celera	3	44,745,206 - 44,817,710 (-)	NCBI		Celera
Cytogenetic Map	3	q21	NCBI

ITGB6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	160,099,671 - 160,200,272 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	160,099,667 - 160,271,888 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	160,956,182 - 161,056,783 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	160,666,479 - 160,764,836 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	160,783,739 - 160,882,097	NCBI
Celera	2	154,569,718 - 154,668,069 (-)	NCBI		Celera
Cytogenetic Map	2	q24.2	NCBI
HuRef	2	152,841,567 - 152,939,796 (-)	NCBI		HuRef
CHM1_1	2	160,964,913 - 161,062,919 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	160,557,539 - 160,657,754 (-)	NCBI		T2T-CHM13v2.0

Itgb6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	60,428,636 - 60,553,005 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	60,428,636 - 60,552,987 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	60,598,292 - 60,722,603 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	60,598,292 - 60,722,643 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	60,436,349 - 60,560,660 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	60,399,131 - 60,474,500 (-)	NCBI		MGSCv36	mm8
Celera	2	62,295,485 - 62,419,857 (-)	NCBI		Celera
Cytogenetic Map	2	C1.1- C1.2	NCBI
cM Map	2	34.81	NCBI

Itgb6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955449	13,448,084 - 13,520,879 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955449	13,387,013 - 13,520,879 (+)	NCBI	ChiLan1.0	ChiLan1.0

ITGB6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	62,791,601 - 62,961,884 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	62,806,572 - 62,909,714 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	47,386,913 - 47,496,491 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	164,757,913 - 164,867,426 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	164,764,251 - 164,867,426 (-)	Ensembl	panpan1.1		panPan2

ITGB6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	36	5,833,206 - 5,962,699 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	36	5,834,638 - 5,962,633 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	36	5,972,263 - 6,101,021 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	36	5,957,679 - 6,086,682 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	36	5,957,684 - 6,086,586 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	36	5,974,904 - 6,103,502 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	36	6,018,081 - 6,146,821 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	36	6,127,531 - 6,256,234 (-)	NCBI		UU_Cfam_GSD_1.0

Itgb6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	122,961,499 - 123,089,078 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936469	18,581,840 - 18,650,123 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936469	18,581,855 - 18,650,109 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ITGB6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	67,041,522 - 67,175,234 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	67,041,516 - 67,175,409 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	74,181,822 - 74,276,814 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ITGB6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	45,506,355 - 45,650,979 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	45,504,987 - 45,595,543 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	153,971,887 - 154,066,448 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Itgb6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624732	5,403,956 - 5,499,855 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624732	5,348,589 - 5,499,826 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Itgb6
593 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	46
Count of miRNA genes:	34
Interacting mature miRNAs:	40
Transcripts:	ENSRNOT00000011030
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10401810	Kidm53	Kidney mass QTL 53			kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	8227194	47233430	Rat
2298542	Neuinf11	Neuroinflammation QTL 11	3.9		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	3	15005422	76927699	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	38192233	133483320	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	29463235	118376539	Rat
9590286	Uminl1	Urine mineral level QTL 1	3.5	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	3	28249687	73249687	Rat
10450816	Scl75	Serum cholesterol level QTL 75	4.4	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	38192233	50749747	Rat
2313093	Bmd77	Bone mineral density QTL 77	2.2	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	3	27494621	50302886	Rat
1581503	Cm58	Cardiac mass QTL 58	2.7	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	43827364	121056321	Rat
12879852	Cm93	Cardiac mass QTL 93		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	3	18311454	47233430	Rat
12879853	Am5	Aortic mass QTL 5		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	3	18311454	47233430	Rat
12879854	Kidm63	Kidney mass QTL 63		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	18311454	47233430	Rat
61356	Bp37	Blood pressure QTL 37	3		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	3	30684642	75684642	Rat
1358905	Hrtrt17	Heart rate QTL 17	5.9	0.000014	heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	10861912	89878372	Rat
12879849	Bw180	Body weight QTL 180		0.037	body mass (VT:0001259)	body weight (CMO:0000012)	3	18311454	47233430	Rat
70191	BpQTLcluster4	Blood pressure QTL cluster 4	3		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	3	10778704	50302886	Rat
12879850	Cm91	Cardiac mass QTL 91		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	3	18311454	47233430	Rat
2313101	Bmd76	Bone mineral density QTL 76	3.6	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	3	27494621	50302886	Rat
731172	Bp151	Blood pressure QTL 151		0.04	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	18311454	47233430	Rat
12879851	Cm92	Cardiac mass QTL 92		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	18311454	47233430	Rat
8694196	Abfw2	Abdominal fat weight QTL 2	16.58	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	3	28249687	73249687	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	41874578	155617519	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	41874578	155617519	Rat
2290452	Scl56	Serum cholesterol level QTL 56	2.26		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	3	1	91609953	Rat
12879868	Am6	Aortic mass QTL 6		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	3	31426403	70668733	Rat
11565451	Bw177	Body weight QTL 177		0.002	body mass (VT:0001259)	body weight (CMO:0000012)	3	31426403	70668733	Rat
10450852	Stl33	Serum triglyceride level QTL 33	3.4	0.05	blood LDL triglyceride amount (VT:0010699)	blood lipoprotein triglyceride level (CMO:0002685)	3	38192233	50749747	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
11565452	Kidm57	Kidney mass QTL 57		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	31426403	70668733	Rat
4889975	Bmd81	Bone mineral density QTL 81	4.3		tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	3	38710365	50302886	Rat
12879866	Cm94	Cardiac mass QTL 94		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	31426403	70668733	Rat
12879867	Cm95	Cardiac mass QTL 95		0.047	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	3	31426403	70668733	Rat
1300178	Hrtrt4	Heart rate QTL 4	3.74		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	43827364	90905114	Rat
2302055	Pia30	Pristane induced arthritis QTL 30	3.5	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)	3	27936919	72936919	Rat
634317	Bw117	Body weight QTL 117	3.58		abdominal fat pad mass (VT:1000711)	abdominal fat pad weight to body weight ratio (CMO:0000095)	3	39454637	53296578	Rat
1331795	Rf30	Renal function QTL 30	3.708		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	3	39454637	89115240	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	31172320	163586636	Rat
1354589	Bw31	Body weight QTL 31	3.3		body mass (VT:0001259)	body weight (CMO:0000012)	3	33703347	78196190	Rat
2303593	Gluco46	Glucose level QTL 46	3		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	28468571	73468571	Rat
1354590	Despr11	Despair related QTL 11		0.000031	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	3	28468571	73468571	Rat
2313079	Bss73	Bone structure and strength QTL 73	1.5		tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	3	27494621	50302886	Rat
1331777	Bw24	Body weight QTL 24	3.503		body mass (VT:0001259)	body weight (CMO:0000012)	3	39454637	89115240	Rat
631647	Bp122	Blood pressure QTL 122	6.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	30684642	75684642	Rat
2313076	Bss74	Bone structure and strength QTL 74	2	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	3	27494621	50302886	Rat
1300169	Bp177	Blood pressure QTL 177	2.96		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	3	33703347	61017857	Rat
10450813	Scl74	Serum cholesterol level QTL 74	5.8	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	38192233	50749747	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	43827364	169034231	Rat
2302276	Bw82	Body weight QTL 82	4.32		body mass (VT:0001259)	body weight (CMO:0000012)	3	39454637	62951183	Rat
738019	Anxrr10	Anxiety related response QTL 10	3.9		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	3	38517803	83517803	Rat
9590136	Scort3	Serum corticosterone level QTL 3	23.37	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	28249687	73249687	Rat
10450804	Scl70	Serum cholesterol level QTL 70	4.7	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	20714090	65714090	Rat
61419	Cia11	Collagen induced arthritis QTL 11	5.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	3	30356773	98535386	Rat
1354597	Kidm13	Kidney mass QTL 13	2.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	3	41874578	104104347	Rat
8552950	Pigfal12	Plasma insulin-like growth factor 1 level QTL 12	7.3		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	3	28249687	73249687	Rat
631676	Cm8	Cardiac mass QTL 8	7.03	0.0001	aorta mass (VT:0002845)	aorta weight (CMO:0000076)	3	16954708	61954708	Rat
10450794	Scl69	Serum cholesterol level QTL 69	6.3	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	20714090	65714090	Rat
8694386	Bw159	Body weight QTL 159	4.52	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	3	28249687	73249687	Rat
1354604	Bw36	Body weight QTL 36	2.9		body mass (VT:0001259)	body weight (CMO:0000012)	3	33703347	104104347	Rat
2313049	Bss72	Bone structure and strength QTL 72	2.6	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	3	27494621	50302886	Rat
2301400	Cm68	Cardiac mass QTL 68		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	3	31426403	70668733	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	104	90	90	59	25	59	6	217	96	85	45	57	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001004263	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001431676	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001431677	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006234232	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006234233	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008761845	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008761846	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017591686	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC079069	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000011030 ⟹ ENSRNOP00000011030

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	45,048,044 - 45,121,671 (-)	Ensembl
Rnor_6.0 Ensembl	3	46,654,373 - 46,726,946 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000086576 ⟹ ENSRNOP00000074271

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	3	46,652,623 - 46,726,958 (-)	Ensembl

RefSeq Acc Id:

NM_001004263 ⟹ NP_001004263

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	65,456,690 - 65,530,333 (-)	NCBI
mRatBN7.2	3	45,048,021 - 45,121,671 (-)	NCBI
Rnor_6.0	3	46,654,350 - 46,726,946 (-)	NCBI
Rnor_5.0	3	51,760,871 - 51,883,770 (-)	NCBI
RGSC_v3.4	3	42,286,140 - 42,360,793 (-)	RGD
Celera	3	44,745,206 - 44,817,710 (-)	RGD

Sequence:

show sequence

GTCTTAATGAAAGCTTTCGAATTTACAGCTCAAGTTACTTTTCAAAGCAGTTGAAAACTGAACC
GAATGGGGATTGAGCTGGTCTGCCTGTTCCTGCTACTTCTAGGAAGGAATGATCACGTCCAAGG
TGGCTGTGCCTGGAGTGGTGCAGAAACCTGCTCAGACTGCCTGCTCACAGGACCTCACTGCGCC
TGGTGCTCCCAGGAGAATTTCACCCACCTGTCCGGAGCTGGCGAAAGGTGCGACACCCCCGAGA
ATCTTTTAGCCAAAGGATGTCAGTTACCCTTCATCGAAAACCCTGTCTCCCAAGTAGAAATACT
TCAAAATAAGCCTCTCAGCGTAGGTCGACAGAAAAACAGTTCTGACATTGTTCAGATTGCTCCT
CAAAGCTTGGTTCTTAAGTTGAGACCAGGGGGTGAGCAGACTCTGCAAGTGCAGGTCCGCCAGA
CGGAAGATTACCCAGTAGATCTGTATTACCTCATGGACCTCTCGGCCTCCATGGATGATGACCT
CAACACAATCAAAGAGCTTGGCTCCCGGCTGGCCAAAGAGATGTCTAAATTAACCAGCAACTTT
AGACTGGGCTTTGGCTCTTTTGTGGAAAAGCCCGTTTCTCCTTTTATGAAAACAACACCAGAGG
AAATCACCAACCCTTGCAGTAGTATCCCCTATTTCTGCTTACCTACATTTGGATTCAAGCACAT
TTTGCCATTGACTGATGATGCTGAGAGATTCAATGAAATTGTGAGGAAACAGAAGATTTCCGCT
AATATTGACACGCCTGAAGGCGGATTCGATGCCATCATGCAAGCTGCTGTGTGTAAGGAAAAGA
TTGGCTGGCGCAACGACTCGCTCCACCTCCTGGTTTTTGTGAGTGATGCTGATTCTCATTTTGG
AATGGACAGCAAGCTGGCAGGCATTGTGATTCCCAACGATGGGCTCTGTCACTTGGACAACAGG
AATGAATACTCCATGTCAACTGTCTTGGAATATCCAACGATCGGCCAACTCATTGATAAACTGG
TACAAAACAACGTGCTACTGATCTTTGCGGTCACCCAAGAACAAGTCCATCTCTATGAGAATTA
TGCGAAACTCATCCCTGGAGCGACTGTGGGACTGCTTCAGAAGGATTCTGGGAACATTCTTCAG
CTGATCATCTCCGCTTACGAAGAACTGCGGTCTGAGGTGGAACTAGAAGTATTAGGAGACACAG
AAGGACTCAACCTGTCTTTCACAGCTCTCTGTAGCAATGGCATCCTCTTCCCACACCAAAAGAA
GTGTTCCCACATGAAAGTCGGAGATACAGCATCCTTCAACGTGTCTGTGAGCATAACAAACTGT
GAGAAAAGAAGCAGGAAACTTATCATCAAGCCTGTGGGACTTGGGGACACCCTGGAAATACTCG
TCAGCGCAGAATGTGACTGCGACTGCCAGAGAGAAGTAGAAGCCAACAGTTCTAAGTGCCACCA
CGGGAATGGCTCCTTCCAGTGTGGGGTGTGTGCCTGCAACCCTGGCCACATGGGTCCTCGCTGC
GAGTGCGGCGAGGACATGGTGAGCACGGATTCCTGCAAGGAGTCCCCAGGTCACCCCTCCTGCA
GCGGAAGGGGTGACTGCTATTGTGGGCAGTGTGTCTGCCACTTGTCTCCCTATGGAAGCATCTA
TGGACCTTACTGCCAGTGTGACAACTTCTCCTGTCTGAGACACAAAGGCCTGCTCTGTGGAGAT
AATGGTGACTGTGACTGTGGTGAATGCGTGTGCCGGGATGGCTGGACGGGCGAGTACTGCAACT
GTACAACCAGCAGGGATGCGTGTGCATCGGAAGATGGCGTGCTGTGCAGCGGGCGTGGGGACTG
TGTCTGCGGCAAGTGTGTCTGCAGAAACCCTGGAGCCTCGGGACCCACCTGTGAACGCTGCCCT
ACCTGTGGAGACCCCTGTAACTCGAGACGGAGCTGCATCGAGTGCTACCTGTCTGCAGATGGCC
AGGCCCAAGAAGAGTGCGAGGACAAGTGCAAAGCCACCGGTGCCACCATCAGTGAGGAAGAGTT
TTCAAAGGATACTTCTGTCCCCTGCTCGCTACAAGGAGAAAATGAATGTCTTATTACATTCCTA
ATAACTGCGGATAATGAAGGGAAAACCATCATTCACAACATCAGTGAAAAAGACTGCCCCAAAC
CTCCAAACATTCCCATGATCATGTTGGGGGTGTCACTGGCTATCCTGCTCATCGGTGTCGTGCT
ACTGTGCATTTGGAAGCTGCTGGTATCCTTTCACGACCGGAAAGAAGTTGCTAAATTTGAAGCA
GAACGATCAAAGGCCAAGTGGCAAACGGGAACCAATCCGCTGTACCGAGGCTCCACCAGCACTT
TTAAGAACGTGACCTACAAACACAGGGAGAAGCACAAAGTGGGCCTTTCTTCAGATGGGTAGAC
AGACCTCCTTCGGCCAGAGAAAGTCAGCTCTGCTTACGTTAAAGGTTAATGCACTGTATGATTT
GTCTTCCTTTGTTTCGTCAAAAGGAGGTTGACTTAAGATACTAACAGGTCATTCAGAGATCAGT
CATTCAGGGCGTGAAGGTGAGACATTGTTTGCAAGTTGGAAATAATCAAGAAAAGAATATCCCA
AGCAAAGAGGTGAATTCAAGATCACTTGAAGAATATGAACTCTGACGCATTAATGCCTCAAAAA
AAATCATCAAAATGATTCATGGGGATTTGATTTGCATTTGAAAAATGTTCAGAATTAGAATCTC
ATTTGCTTCCTGAATCCAGCTACCTAAAGTCTTTGTCTCTAAAAAAAAAAAAAAAAAAAAAAAA
AA

hide sequence

RefSeq Acc Id:

XM_006234232 ⟹ XP_006234294

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	65,454,964 - 65,579,179 (-)	NCBI
mRatBN7.2	3	45,046,295 - 45,170,532 (-)	NCBI
Rnor_6.0	3	46,652,624 - 46,775,362 (-)	NCBI
Rnor_5.0	3	51,760,871 - 51,883,770 (-)	NCBI

Sequence:

show sequence

AATCAGCCAGGCGCTCTGTCACTCACCAGCAGTGTCTCTGCCTAGCGGTGTACACCCACATGCC
TTTTATGAGATGTCTCGTTTGTGCTGGTGGAAGAAATAGTCCCATGAGCGTGCTTTTTTTCAGG
GATGGTGACCGCAGAATGGTTTAAGTCTAGTCACTACCACAAGGATCAATGGCGCTTCTGCCAA
AGACTTTGCTCACGGGTACAGTAACGCATGTCAGCACTTTCTGAGATTAGAGGGTCTCCCGTGT
GAGGTTTCTCACGCCTGCCTGGAAACATACCTTCAAAAGATAGTCTCCCAGGCCTTGAGCTGAG
ACATAAAGGAGCCTGCCTAAGAGCTCGTTTGAATTCTCTGCAGAGGCTCTAACATGAAAACCAA
AAATTTCAGTGAAAACTGAACCGAATGGGGATTGAGCTGGTCTGCCTGTTCCTGCTACTTCTAG
GAAGGAATGATCACGTCCAAGGTGGCTGTGCCTGGAGTGGTGCAGAAACCTGCTCAGACTGCCT
GCTCACAGGACCTCACTGCGCCTGGTGCTCCCAGGAGAATTTCACCCACCTGTCCGGAGCTGGC
GAAAGGTGCGACACCCCCGAGAATCTTTTAGCCAAAGGATGTCAGTTACCCTTCATCGAAAACC
CTGTCTCCCAAGTAGAAATACTTCAAAATAAGCCTCTCAGCGTAGGTCGACAGAAAAACAGTTC
TGACATTGTTCAGATTGCTCCTCAAAGCTTGGTTCTTAAGTTGAGACCAGGGGGTGAGCAGACT
CTGCAAGTGCAGGTCCGCCAGACGGAAGATTACCCAGTAGATCTGTATTACCTCATGGACCTCT
CGGCCTCCATGGATGATGACCTCAACACAATCAAAGAGCTTGGCTCCCGGCTGGCCAAAGAGAT
GTCTAAATTAACCAGCAACTTTAGACTGGGCTTTGGCTCTTTTGTGGAAAAGCCCGTTTCTCCT
TTTATGAAAACAACACCAGAGGAAATCACCAACCCTTGCAGTAGTATCCCCTATTTCTGCTTAC
CTACATTTGGATTCAAGCACATTTTGCCATTGACTGATGATGCTGAGAGATTCAATGAAATTGT
GAGGAAACAGAAGATTTCCGCTAATATTGACACGCCTGAAGGCGGATTCGATGCCATCATGCAA
GCTGCTGTGTGTAAGGAAAAGATTGGCTGGCGCAACGACTCGCTCCACCTCCTGGTTTTTGTGA
GTGATGCTGATTCTCATTTTGGAATGGACAGCAAGCTGGCAGGCATTGTGATTCCCAACGATGG
GCTCTGTCACTTGGACAACAGGAATGAATACTCCATGTCAACTGTCTTGGAATATCCAACGATC
GGCCAACTCATTGATAAACTGGTACAAAACAACGTGCTACTGATCTTTGCGGTCACCCAAGAAC
AAGTCCATCTCTATGAGAATTATGCGAAACTCATCCCTGGAGCGACTGTGGGACTGCTTCAGAA
GGATTCTGGGAACATTCTTCAGCTGATCATCTCCGCTTACGAAGAACTGCGGTCTGAGGTGGAA
CTAGAAGTATTAGGAGACACAGAAGGACTCAACCTGTCTTTCACAGCTCTCTGTAGCAATGGCA
TCCTCTTCCCACACCAAAAGAAGTGTTCCCACATGAAAGTCGGAGATACAGCATCCTTCAACGT
GTCTGTGAGCATAACAAACTGTGAGAAAAGAAGCAGGAAACTTATCATCAAGCCTGTGGGACTT
GGGGACACCCTGGAAATACTCGTCAGCGCAGAATGTGACTGCGACTGCCAGAGAGAAGTAGAAG
CCAACAGTTCTAAGTGCCACCACGGGAATGGCTCCTTCCAGTGTGGGGTGTGTGCCTGCAACCC
TGGCCACATGGGTCCTCGCTGCGAGTGCGGCGAGGACATGGTGAGCACGGATTCCTGCAAGGAG
TCCCCAGGTCACCCCTCCTGCAGCGGAAGGGGTGACTGCTATTGTGGGCAGTGTGTCTGCCACT
TGTCTCCCTATGGAAGCATCTATGGACCTTACTGCCAGTGTGACAACTTCTCCTGTCTGAGACA
CAAAGGCCTGCTCTGTGGAGATAATGGTGACTGTGACTGTGGTGAATGCGTGTGCCGGGATGGC
TGGACGGGCGAGTACTGCAACTGTACAACCAGCAGGGATGCGTGTGCATCGGAAGATGGCGTGC
TGTGCAGCGGGCGTGGGGACTGTGTCTGCGGCAAGTGTGTCTGCAGAAACCCTGGAGCCTCGGG
ACCCACCTGTGAACGCTGCCCTACCTGTGGAGACCCCTGTAACTCGAGACGGAGCTGCATCGAG
TGCTACCTGTCTGCAGATGGCCAGGCCCAAGAAGAGTGCGAGGACAAGTGCAAAGCCACCGGTG
CCACCATCAGTGAGGAAGAGTTTTCAAAGGATACTTCTGTCCCCTGCTCGCTACAAGGAGAAAA
TGAATGTCTTATTACATTCCTAATAACTGCGGATAATGAAGGGAAAACCATCATTCACAACATC
AGTGAAAAAGACTGCCCCAAACCTCCAAACATTCCCATGATCATGTTGGGGGTGTCACTGGCTA
TCCTGCTCATCGGTGTCGTGCTACTGTGCATTTGGAAGCTGCTGGTATCCTTTCACGACCGGAA
AGAAGTTGCTAAATTTGAAGCAGAACGATCAAAGGCCAAGTGGCAAACGGGAACCAATCCGCTG
TACCGAGGCTCCACCAGCACTTTTAAGAACGTGACCTACAAACACAGGGAGAAGCACAAAGTGG
GCCTTTCTTCAGATGGGTAGACAGACCTCCTTCGGCCAGAGAAAGTCAGCTCTGCTTACGTTAA
AGGTTAATGCACTGTATGATTTGTCTTCCTTTGTTTCGTCAAAAGGAGGTTGACTTAAGATACT
AACAGGTCATTCAGAGATCAGTCATTCAGGGCGTGAAGGTGAGACATTGTTTGCAAGTTGGAAA
TAATCAAGAAAAGAATATCCCAAGCAAAGAGGTGAATTCAAGATCACTTGAAGAATATGAACTC
TGACGCATTAATGCCTCAAAAAAAATCATCAAAATGATTCATGGGGATTTGATTTGCATTTGAA
AAATGTTCAGAATTAGAATCTCATTTGCTTCCTGAATCCAGCTACCTAAAGTCTTTGTCTCTAA
AAAAAAAAAAAAAAAAAAAAATTGTATACCCACAGAAACCGCTTATTCTGAACTTGCAGAAGGT
CTATTTCCTATTTCCTGAAGGAATTTGTTTCTTTGGTTGGTTTGTTGGTTGTTTTTGAGAAAGG
GTGTCTCTGTAGCTGCTCTGGAATTGACCAGGCTGCCTGGCCTTGAACTGGGAAACGATCTGCT
TGTTTCTGCCTCTTGAGTGCCGGGATTAAAGATGTGACATGTCATGCTCAGTGACCTTAACTTT
CATGTATGAGAAATGAGAGTCTGGTTTCCCATCAGCTGAAAGAATCCAGTTCTCCCAGTGATCT
CCTAAGGGAGAGATTGAAAATTAAATGGTAATCATGGTCATGGGTTTGTACACTTAAAAGTCAT
GGACACAAATATTTTGTTTCAAAGATGAGGAAAGGGTAATTTATAAATTACATTGCTTGTAACA
CTGAAGTAACACTGCTTGCTTAATTGCTCTCTGGTCCCCAAGTTTCCCTCCTATTATTACATAT
TATTGCACACAGCTACAGTCTTCAAAACTCCACAAGTATCATACAAAGGTGTCCACCTTTTTAA
AAAATCACTTTAAGTTATACACGGATCAACTAGAATTTCAGGAATAGAAAAGAAACCTAGGCTA
ACAGAATAAAAGGCCACATGGTTTTTCATCAAGCATGTCAAGACTTCGGAAGTCCCTCATGGAG
TCTGCCCTTCCTAAAGGATATTCCTTTCCCATGTGCACCACCCAGCACATACATCCCAGCTTCA
GGGAGTGGGCGTGCCACCTACTTACTTTAAAAAGTAAGACCACTTACAAAATCCATACAGGCAA
CAAACCAACCTGTAGCAGGTTGGAGGAATAGTATCTGGAGGGTTTTGCTCCTTATGGTTACTGC
TGCATTACAAAGCACTTTGATCTCACTGGATCTCCACAGAGAAGCTGAGAGAGTGGGCAGAAGA
GCTCCTGCAGACTCTCTAGCTTATAACTCTAAGCCCTTTGTTCTCTCTCATGCACGACACTCTT
TTGTCAGTAAAATGATAGAAGGATTGTATTAGTTATGGTATAACTATCTTAGTTTGAAAGTGTA
CTGACACAAAACGAATAGCACGCGGGTCCCTGGAATGTGGGCCGGTTGCTGTATTTTTTGTGCA
GTGTGTATTGCCTTAACTGGATATTAAGGTGAAGCCACTCCCTAGGTGAATGGCCCCATGTTAG
TGGAGGCTTTAACCGTTGTCTGTTGAATTGTCAGCTTGGTCAAACCTCCTTTACTCCTGCCAGA
TAGGTCTGTGTACGTTTTCACATCATCTAGTTCTTTCTTTTTTTGGTTTTTAATAACTCAGGTA
AATTAGTCAGTTAGGGAGGACATGGCTAAATTTAAAAGAAAAATCTTAATGAATCTCCTTTGGG
TCCCTGAATGGTCCAAGACCTTGGAGTCTGGGGCAACCAGCAAATGCACTCTTAGTGACATGGT
GGTACTGCTGCCTCTGAGCTGTCTCTTCTGCTTTTGTGTTATTGCTGGAATGAGATTTTAGAAA
ATAGAAGTTTCTCTCATGTGTGTATCAGGAAGAATTTGTTCTTTCTCTAATTACTGTTTTGACC
CAAGGCAGGACCTTGAAAGGGTCAAAACATTAACAGTAGTGCTTCTGTTCACTGAAGAATTATG
TTACATGAAGATAAAATGGTTGGTTTTTTAAAAAGTGGTTTTATTGTTGCGTTGACATAAATAA
ACGTAATTTAAACAATGAA

hide sequence

RefSeq Acc Id:

XM_006234233 ⟹ XP_006234295

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	65,454,964 - 65,530,404 (-)	NCBI
mRatBN7.2	3	45,046,295 - 45,121,737 (-)	NCBI
Rnor_6.0	3	46,652,624 - 46,727,265 (-)	NCBI
Rnor_5.0	3	51,760,871 - 51,883,770 (-)	NCBI

Sequence:

show sequence

TTAGCTTAAGTTCTGGTGTTTTGCTTCACATCCTCACTGCCTTAAACTAAAAATTGTCATAAGA
AGCATACATTTAAATCCGTCTTTTGACAGCTCCTTGATTAGCATTTCACTGAAGAGACCGAGTC
TCTCTAGGATACAGTACAGCTAATAGAATGCTCACACATAAAAATGTCTCCTGCACCCGAGTCT
CCCCACCTTCTCGGTGATTGCACACCTGACTTCCTTATAAGGCGAATGAGGAAGTACGCATGTT
GAAGTTGCTTTTAAACACAGCTTTTCTTCTTTGCCTGGCCAGTGAAAACTGAACCGAATGGGGA
TTGAGCTGGTCTGCCTGTTCCTGCTACTTCTAGGAAGGAATGATCACGTCCAAGGTGGCTGTGC
CTGGAGTGGTGCAGAAACCTGCTCAGACTGCCTGCTCACAGGACCTCACTGCGCCTGGTGCTCC
CAGGAGAATTTCACCCACCTGTCCGGAGCTGGCGAAAGGTGCGACACCCCCGAGAATCTTTTAG
CCAAAGGATGTCAGTTACCCTTCATCGAAAACCCTGTCTCCCAAGTAGAAATACTTCAAAATAA
GCCTCTCAGCGTAGGTCGACAGAAAAACAGTTCTGACATTGTTCAGATTGCTCCTCAAAGCTTG
GTTCTTAAGTTGAGACCAGGGGGTGAGCAGACTCTGCAAGTGCAGGTCCGCCAGACGGAAGATT
ACCCAGTAGATCTGTATTACCTCATGGACCTCTCGGCCTCCATGGATGATGACCTCAACACAAT
CAAAGAGCTTGGCTCCCGGCTGGCCAAAGAGATGTCTAAATTAACCAGCAACTTTAGACTGGGC
TTTGGCTCTTTTGTGGAAAAGCCCGTTTCTCCTTTTATGAAAACAACACCAGAGGAAATCACCA
ACCCTTGCAGTAGTATCCCCTATTTCTGCTTACCTACATTTGGATTCAAGCACATTTTGCCATT
GACTGATGATGCTGAGAGATTCAATGAAATTGTGAGGAAACAGAAGATTTCCGCTAATATTGAC
ACGCCTGAAGGCGGATTCGATGCCATCATGCAAGCTGCTGTGTGTAAGGAAAAGATTGGCTGGC
GCAACGACTCGCTCCACCTCCTGGTTTTTGTGAGTGATGCTGATTCTCATTTTGGAATGGACAG
CAAGCTGGCAGGCATTGTGATTCCCAACGATGGGCTCTGTCACTTGGACAACAGGAATGAATAC
TCCATGTCAACTGTCTTGGAATATCCAACGATCGGCCAACTCATTGATAAACTGGTACAAAACA
ACGTGCTACTGATCTTTGCGGTCACCCAAGAACAAGTCCATCTCTATGAGAATTATGCGAAACT
CATCCCTGGAGCGACTGTGGGACTGCTTCAGAAGGATTCTGGGAACATTCTTCAGCTGATCATC
TCCGCTTACGAAGAACTGCGGTCTGAGGTGGAACTAGAAGTATTAGGAGACACAGAAGGACTCA
ACCTGTCTTTCACAGCTCTCTGTAGCAATGGCATCCTCTTCCCACACCAAAAGAAGTGTTCCCA
CATGAAAGTCGGAGATACAGCATCCTTCAACGTGTCTGTGAGCATAACAAACTGTGAGAAAAGA
AGCAGGAAACTTATCATCAAGCCTGTGGGACTTGGGGACACCCTGGAAATACTCGTCAGCGCAG
AATGTGACTGCGACTGCCAGAGAGAAGTAGAAGCCAACAGTTCTAAGTGCCACCACGGGAATGG
CTCCTTCCAGTGTGGGGTGTGTGCCTGCAACCCTGGCCACATGGGTCCTCGCTGCGAGTGCGGC
GAGGACATGGTGAGCACGGATTCCTGCAAGGAGTCCCCAGGTCACCCCTCCTGCAGCGGAAGGG
GTGACTGCTATTGTGGGCAGTGTGTCTGCCACTTGTCTCCCTATGGAAGCATCTATGGACCTTA
CTGCCAGTGTGACAACTTCTCCTGTCTGAGACACAAAGGCCTGCTCTGTGGAGATAATGGTGAC
TGTGACTGTGGTGAATGCGTGTGCCGGGATGGCTGGACGGGCGAGTACTGCAACTGTACAACCA
GCAGGGATGCGTGTGCATCGGAAGATGGCGTGCTGTGCAGCGGGCGTGGGGACTGTGTCTGCGG
CAAGTGTGTCTGCAGAAACCCTGGAGCCTCGGGACCCACCTGTGAACGCTGCCCTACCTGTGGA
GACCCCTGTAACTCGAGACGGAGCTGCATCGAGTGCTACCTGTCTGCAGATGGCCAGGCCCAAG
AAGAGTGCGAGGACAAGTGCAAAGCCACCGGTGCCACCATCAGTGAGGAAGAGTTTTCAAAGGA
TACTTCTGTCCCCTGCTCGCTACAAGGAGAAAATGAATGTCTTATTACATTCCTAATAACTGCG
GATAATGAAGGGAAAACCATCATTCACAACATCAGTGAAAAAGACTGCCCCAAACCTCCAAACA
TTCCCATGATCATGTTGGGGGTGTCACTGGCTATCCTGCTCATCGGTGTCGTGCTACTGTGCAT
TTGGAAGCTGCTGGTATCCTTTCACGACCGGAAAGAAGTTGCTAAATTTGAAGCAGAACGATCA
AAGGCCAAGTGGCAAACGGGAACCAATCCGCTGTACCGAGGCTCCACCAGCACTTTTAAGAACG
TGACCTACAAACACAGGGAGAAGCACAAAGTGGGCCTTTCTTCAGATGGGTAGACAGACCTCCT
TCGGCCAGAGAAAGTCAGCTCTGCTTACGTTAAAGGTTAATGCACTGTATGATTTGTCTTCCTT
TGTTTCGTCAAAAGGAGGTTGACTTAAGATACTAACAGGTCATTCAGAGATCAGTCATTCAGGG
CGTGAAGGTGAGACATTGTTTGCAAGTTGGAAATAATCAAGAAAAGAATATCCCAAGCAAAGAG
GTGAATTCAAGATCACTTGAAGAATATGAACTCTGACGCATTAATGCCTCAAAAAAAATCATCA
AAATGATTCATGGGGATTTGATTTGCATTTGAAAAATGTTCAGAATTAGAATCTCATTTGCTTC
CTGAATCCAGCTACCTAAAGTCTTTGTCTCTAAAAAAAAAAAAAAAAAAAAAAATTGTATACCC
ACAGAAACCGCTTATTCTGAACTTGCAGAAGGTCTATTTCCTATTTCCTGAAGGAATTTGTTTC
TTTGGTTGGTTTGTTGGTTGTTTTTGAGAAAGGGTGTCTCTGTAGCTGCTCTGGAATTGACCAG
GCTGCCTGGCCTTGAACTGGGAAACGATCTGCTTGTTTCTGCCTCTTGAGTGCCGGGATTAAAG
ATGTGACATGTCATGCTCAGTGACCTTAACTTTCATGTATGAGAAATGAGAGTCTGGTTTCCCA
TCAGCTGAAAGAATCCAGTTCTCCCAGTGATCTCCTAAGGGAGAGATTGAAAATTAAATGGTAA
TCATGGTCATGGGTTTGTACACTTAAAAGTCATGGACACAAATATTTTGTTTCAAAGATGAGGA
AAGGGTAATTTATAAATTACATTGCTTGTAACACTGAAGTAACACTGCTTGCTTAATTGCTCTC
TGGTCCCCAAGTTTCCCTCCTATTATTACATATTATTGCACACAGCTACAGTCTTCAAAACTCC
ACAAGTATCATACAAAGGTGTCCACCTTTTTAAAAAATCACTTTAAGTTATACACGGATCAACT
AGAATTTCAGGAATAGAAAAGAAACCTAGGCTAACAGAATAAAAGGCCACATGGTTTTTCATCA
AGCATGTCAAGACTTCGGAAGTCCCTCATGGAGTCTGCCCTTCCTAAAGGATATTCCTTTCCCA
TGTGCACCACCCAGCACATACATCCCAGCTTCAGGGAGTGGGCGTGCCACCTACTTACTTTAAA
AAGTAAGACCACTTACAAAATCCATACAGGCAACAAACCAACCTGTAGCAGGTTGGAGGAATAG
TATCTGGAGGGTTTTGCTCCTTATGGTTACTGCTGCATTACAAAGCACTTTGATCTCACTGGAT
CTCCACAGAGAAGCTGAGAGAGTGGGCAGAAGAGCTCCTGCAGACTCTCTAGCTTATAACTCTA
AGCCCTTTGTTCTCTCTCATGCACGACACTCTTTTGTCAGTAAAATGATAGAAGGATTGTATTA
GTTATGGTATAACTATCTTAGTTTGAAAGTGTACTGACACAAAACGAATAGCACGCGGGTCCCT
GGAATGTGGGCCGGTTGCTGTATTTTTTGTGCAGTGTGTATTGCCTTAACTGGATATTAAGGTG
AAGCCACTCCCTAGGTGAATGGCCCCATGTTAGTGGAGGCTTTAACCGTTGTCTGTTGAATTGT
CAGCTTGGTCAAACCTCCTTTACTCCTGCCAGATAGGTCTGTGTACGTTTTCACATCATCTAGT
TCTTTCTTTTTTTGGTTTTTAATAACTCAGGTAAATTAGTCAGTTAGGGAGGACATGGCTAAAT
TTAAAAGAAAAATCTTAATGAATCTCCTTTGGGTCCCTGAATGGTCCAAGACCTTGGAGTCTGG
GGCAACCAGCAAATGCACTCTTAGTGACATGGTGGTACTGCTGCCTCTGAGCTGTCTCTTCTGC
TTTTGTGTTATTGCTGGAATGAGATTTTAGAAAATAGAAGTTTCTCTCATGTGTGTATCAGGAA
GAATTTGTTCTTTCTCTAATTACTGTTTTGACCCAAGGCAGGACCTTGAAAGGGTCAAAACATT
AACAGTAGTGCTTCTGTTCACTGAAGAATTATGTTACATGAAGATAAAATGGTTGGTTTTTTAA
AAAGTGGTTTTATTGTTGCGTTGACATAAATAAACGTAATTTAAACAATGAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001004263	(Get FASTA)	NCBI Sequence Viewer
	NP_001418605	(Get FASTA)	NCBI Sequence Viewer
	NP_001418606	(Get FASTA)	NCBI Sequence Viewer
	XP_006234294	(Get FASTA)	NCBI Sequence Viewer
	XP_006234295	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH79069	(Get FASTA)	NCBI Sequence Viewer
	EDL78984	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000011030.4
	ENSRNOP00055000786
	ENSRNOP00060011695
	ENSRNOP00065028386
GenBank Protein	Q6AYF4	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001004263 ⟸ NM_001004263
- Peptide Label:	precursor
- UniProtKB:	Q6AYF4 (UniProtKB/Swiss-Prot), A6HLT3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGIELVCLFLLLLGRNDHVQGGCAWSGAETCSDCLLTGPHCAWCSQENFTHLSGAGERCDTPEN LLAKGCQLPFIENPVSQVEILQNKPLSVGRQKNSSDIVQIAPQSLVLKLRPGGEQTLQVQVRQT EDYPVDLYYLMDLSASMDDDLNTIKELGSRLAKEMSKLTSNFRLGFGSFVEKPVSPFMKTTPEE ITNPCSSIPYFCLPTFGFKHILPLTDDAERFNEIVRKQKISANIDTPEGGFDAIMQAAVCKEKI GWRNDSLHLLVFVSDADSHFGMDSKLAGIVIPNDGLCHLDNRNEYSMSTVLEYPTIGQLIDKLV QNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEELRSEVELEVLGDTE GLNLSFTALCSNGILFPHQKKCSHMKVGDTASFNVSVSITNCEKRSRKLIIKPVGLGDTLEILV SAECDCDCQREVEANSSKCHHGNGSFQCGVCACNPGHMGPRCECGEDMVSTDSCKESPGHPSCS GRGDCYCGQCVCHLSPYGSIYGPYCQCDNFSCLRHKGLLCGDNGDCDCGECVCRDGWTGEYCNC TTSRDACASEDGVLCSGRGDCVCGKCVCRNPGASGPTCERCPTCGDPCNSRRSCIECYLSADGQ AQEECEDKCKATGATISEEEFSKDTSVPCSLQGENECLITFLITADNEGKTIIHNISEKDCPKP PNIPMIMLGVSLAILLIGVVLLCIWKLLVSFHDRKEVAKFEAERSKAKWQTGTNPLYRGSTSTF KNVTYKHREKHKVGLSSDG hide sequence

RefSeq Acc Id:

XP_006234294 ⟸ XM_006234232

- Peptide Label:

isoform X1

- Sequence:

show sequence

MGIELVCLFLLLLGRNDHVQGGCAWSGAETCSDCLLTGPHCAWCSQENFTHLSGAGERCDTPEN
LLAKGCQLPFIENPVSQVEILQNKPLSVGRQKNSSDIVQIAPQSLVLKLRPGGEQTLQVQVRQT
EDYPVDLYYLMDLSASMDDDLNTIKELGSRLAKEMSKLTSNFRLGFGSFVEKPVSPFMKTTPEE
ITNPCSSIPYFCLPTFGFKHILPLTDDAERFNEIVRKQKISANIDTPEGGFDAIMQAAVCKEKI
GWRNDSLHLLVFVSDADSHFGMDSKLAGIVIPNDGLCHLDNRNEYSMSTVLEYPTIGQLIDKLV
QNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEELRSEVELEVLGDTE
GLNLSFTALCSNGILFPHQKKCSHMKVGDTASFNVSVSITNCEKRSRKLIIKPVGLGDTLEILV
SAECDCDCQREVEANSSKCHHGNGSFQCGVCACNPGHMGPRCECGEDMVSTDSCKESPGHPSCS
GRGDCYCGQCVCHLSPYGSIYGPYCQCDNFSCLRHKGLLCGDNGDCDCGECVCRDGWTGEYCNC
TTSRDACASEDGVLCSGRGDCVCGKCVCRNPGASGPTCERCPTCGDPCNSRRSCIECYLSADGQ
AQEECEDKCKATGATISEEEFSKDTSVPCSLQGENECLITFLITADNEGKTIIHNISEKDCPKP
PNIPMIMLGVSLAILLIGVVLLCIWKLLVSFHDRKEVAKFEAERSKAKWQTGTNPLYRGSTSTF
KNVTYKHREKHKVGLSSDG

hide sequence

RefSeq Acc Id:

XP_006234295 ⟸ XM_006234233

- Peptide Label:

isoform X1

- Sequence:

show sequence

MGIELVCLFLLLLGRNDHVQGGCAWSGAETCSDCLLTGPHCAWCSQENFTHLSGAGERCDTPEN
LLAKGCQLPFIENPVSQVEILQNKPLSVGRQKNSSDIVQIAPQSLVLKLRPGGEQTLQVQVRQT
EDYPVDLYYLMDLSASMDDDLNTIKELGSRLAKEMSKLTSNFRLGFGSFVEKPVSPFMKTTPEE
ITNPCSSIPYFCLPTFGFKHILPLTDDAERFNEIVRKQKISANIDTPEGGFDAIMQAAVCKEKI
GWRNDSLHLLVFVSDADSHFGMDSKLAGIVIPNDGLCHLDNRNEYSMSTVLEYPTIGQLIDKLV
QNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEELRSEVELEVLGDTE
GLNLSFTALCSNGILFPHQKKCSHMKVGDTASFNVSVSITNCEKRSRKLIIKPVGLGDTLEILV
SAECDCDCQREVEANSSKCHHGNGSFQCGVCACNPGHMGPRCECGEDMVSTDSCKESPGHPSCS
GRGDCYCGQCVCHLSPYGSIYGPYCQCDNFSCLRHKGLLCGDNGDCDCGECVCRDGWTGEYCNC
TTSRDACASEDGVLCSGRGDCVCGKCVCRNPGASGPTCERCPTCGDPCNSRRSCIECYLSADGQ
AQEECEDKCKATGATISEEEFSKDTSVPCSLQGENECLITFLITADNEGKTIIHNISEKDCPKP
PNIPMIMLGVSLAILLIGVVLLCIWKLLVSFHDRKEVAKFEAERSKAKWQTGTNPLYRGSTSTF
KNVTYKHREKHKVGLSSDG

hide sequence

Ensembl Acc Id:

ENSRNOP00000074271 ⟸ ENSRNOT00000086576

Ensembl Acc Id:

ENSRNOP00000011030 ⟸ ENSRNOT00000011030

Protein Domains

EGF-like Integrin beta subunit cytoplasmic Integrin beta subunit tail Integrin beta subunit VWA PSI VWFA

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6AYF4-F1-model_v2	AlphaFold	Q6AYF4	1-787	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692103

Promoter ID:

EPDNEW_R2617

Type:

initiation region

Name:

Itgb6_1

Description:

integrin beta 6

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	46,727,009 - 46,727,069	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1303119	AgrOrtholog
BioCyc Gene	G2FUF-49617	BioCyc
Ensembl Genes	ENSRNOG00000008346	Ensembl, UniProtKB/Swiss-Prot
	ENSRNOG00055000591	UniProtKB/Swiss-Prot
	ENSRNOG00060008996	UniProtKB/Swiss-Prot
	ENSRNOG00065020801	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000011030.5	UniProtKB/Swiss-Prot
	ENSRNOT00055001012	UniProtKB/Swiss-Prot
	ENSRNOT00060015070	UniProtKB/Swiss-Prot
	ENSRNOT00065035274	UniProtKB/Swiss-Prot
Gene3D-CATH	3.40.50.410	UniProtKB/Swiss-Prot
	4.10.1240.30	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Cytochrome c1, transmembrane anchor, C-terminal	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Laminin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ligand-binding face of the semaphorins, domain 2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ntegrin, alpha v. Chain A, domain 3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	von Willebrand factor, type A domain	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7121642	IMAGE-MGC_LOAD
InterPro	EGF_extracell	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	I-EGF_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Integrin_beta_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Integrin_bsu	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Integrin_bsu_cyt_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Integrin_bsu_tail	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Integrin_bsu_tail_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Integrin_bsu_VWA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Integrin_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PSI	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	vWFA_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:311061	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:94023	IMAGE-MGC_LOAD
NCBI Gene	311061	ENTREZGENE
PANTHER	INTEGRIN BETA SUBUNIT	UniProtKB/TrEMBL
	INTEGRIN BETA-6	UniProtKB/TrEMBL
	PTHR10082	UniProtKB/Swiss-Prot
	PTHR10082:SF11	UniProtKB/Swiss-Prot
Pfam	EGF_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	I-EGF_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Integrin_b_cyt	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Integrin_B_tail	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Integrin_beta	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PSI_integrin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Itgb6	PhenoGen
PIRSF	Integrin_B	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS	INTEGRINB	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	EGF_1	UniProtKB/Swiss-Prot
	EGF_2	UniProtKB/Swiss-Prot
	INTEGRIN_BETA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000008346	RatGTEx
	ENSRNOG00055000591	RatGTEx
	ENSRNOG00060008996	RatGTEx
	ENSRNOG00065020801	RatGTEx
SMART	INB	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Integrin_b_cyt	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Integrin_B_tail	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PSI	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	EGF/Laminin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Integrin beta tail domain	UniProtKB/TrEMBL
	Integrin domains	UniProtKB/TrEMBL
	Plexin repeat	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF53300	UniProtKB/Swiss-Prot
	SSF69179	UniProtKB/Swiss-Prot
	SSF69687	UniProtKB/Swiss-Prot
	vWA-like	UniProtKB/TrEMBL
UniProt	A6HLT3	ENTREZGENE, UniProtKB/TrEMBL
	ITB6_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-05-29	Itgb6	integrin subunit beta 6	Itgb6	integrin beta 6	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2017-05-16	Itgb6	integrin beta 6	Itgb6	integrin subunit beta 6	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-12-23	Itgb6	integrin subunit beta 6	Itgb6	integrin, beta 6	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Itgb6	integrin, beta 6			Symbol and Name status set to approved	1299863	APPROVED
2005-02-14	Itgb6	integrin, beta 6			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)