Acvr1 (activin A receptor type 1) - Rat Genome Database

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Gene: Acvr1 (activin A receptor type 1) Rattus norvegicus
Analyze
Symbol: Acvr1
Name: activin A receptor type 1
RGD ID: 620200
Description: Exhibits activin receptor activity, type I. Involved in several processes, including cellular response to glucocorticoid stimulus; regulation of skeletal muscle tissue development; and transforming growth factor beta receptor signaling pathway. Localizes to activin receptor complex. Human ortholog(s) of this gene implicated in fibrodysplasia ossificans progressiva. Orthologous to human ACVR1 (activin A receptor type 1); PARTICIPATES IN activin signaling pathway; cytokine mediated signaling pathway; transforming growth factor-beta superfamily mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: activin A receptor, type 1; activin A receptor, type I; activin receptor type I; activin receptor type-1; activin type I receptor; ACTR-I; ALK2-B; serine/threonine-protein kinase receptor R1; SKR1; TGF-B superfamily receptor type I; TSR-I
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2342,978,558 - 43,097,892 (-)NCBI
Rnor_6.0 Ensembl344,432,471 - 44,522,930 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0344,432,476 - 44,539,680 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0349,551,411 - 49,641,517 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4340,191,727 - 40,260,488 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1340,088,098 - 40,156,860 (-)NCBI
Celera341,046,965 - 41,113,654 (-)NCBICelera
Cytogenetic Map3q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activin receptor signaling pathway  (IEA,ISO)
acute inflammatory response  (IEA,ISO)
angiogenesis  (IBA)
atrial septum primum morphogenesis  (IEA,ISO)
atrioventricular valve morphogenesis  (ISO)
BMP signaling pathway  (IBA,ISO)
BMP signaling pathway involved in heart development  (IEA,ISO)
branching involved in blood vessel morphogenesis  (IEA,ISO)
cardiac muscle cell fate commitment  (IEA,ISO)
cellular response to BMP stimulus  (ISO)
cellular response to glucocorticoid stimulus  (IEP)
cellular response to growth factor stimulus  (IBA)
determination of left/right symmetry  (IEA,ISO)
dorsal/ventral pattern formation  (IBA)
embryonic heart tube morphogenesis  (IEA,ISO)
endocardial cushion cell fate commitment  (IEA,ISO)
endocardial cushion fusion  (IEA,ISO)
endocardial cushion morphogenesis  (ISO)
G1/S transition of mitotic cell cycle  (IEA,ISO)
gastrulation  (ISO)
gastrulation with mouth forming second  (IEA,ISO)
germ cell development  (IEA,ISO)
heart development  (IBA,ISO)
in utero embryonic development  (IEA,ISO)
mesoderm development  (ISO)
mesoderm formation  (IEA,ISO)
mitral valve morphogenesis  (IEA,ISO)
negative regulation of activin receptor signaling pathway  (IEA,ISO)
negative regulation of extrinsic apoptotic signaling pathway  (IEA,ISO)
negative regulation of signal transduction  (ISO)
neural crest cell migration  (IEA,ISO)
outflow tract septum morphogenesis  (ISO)
pathway-restricted SMAD protein phosphorylation  (IEA,ISO)
peptidyl-threonine phosphorylation  (IEA,ISO)
pharyngeal system development  (IEA,ISO)
positive regulation of bone mineralization  (IEA,ISO)
positive regulation of cell migration  (IEA,ISO)
positive regulation of determination of dorsal identity  (IEA,ISO)
positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation  (IEA,ISO)
positive regulation of osteoblast differentiation  (IEA,ISO)
positive regulation of pathway-restricted SMAD protein phosphorylation  (IEA,ISO)
positive regulation of peptidyl-tyrosine phosphorylation  (IEA,ISO)
positive regulation of transcription by RNA polymerase II  (IEA,ISO)
positive regulation of transcription, DNA-templated  (ISO)
protein phosphorylation  (IBA,ISO,TAS)
regulation of ossification  (ISO)
regulation of skeletal muscle tissue development  (IEP)
smooth muscle cell differentiation  (IEA,ISO)
transforming growth factor beta receptor signaling pathway  (IBA,IEA,IMP,ISO)
ventricular septum morphogenesis  (IEA,ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:1646080   PMID:7577669   PMID:8242742   PMID:8388127   PMID:8395914   PMID:9884026   PMID:10226013   PMID:10479450   PMID:10704880   PMID:11290335   PMID:12054694   PMID:12065756  
PMID:12151307   PMID:12477932   PMID:14729481   PMID:14993131   PMID:15037318   PMID:15226263   PMID:15289457   PMID:15531373   PMID:16140292   PMID:16420278   PMID:16642017   PMID:17078885  
PMID:17117439   PMID:18326817   PMID:18436533   PMID:19506109   PMID:19736306   PMID:22871113   PMID:26598555   PMID:26873969  


Genomics

Comparative Map Data
Acvr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2342,978,558 - 43,097,892 (-)NCBI
Rnor_6.0 Ensembl344,432,471 - 44,522,930 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0344,432,476 - 44,539,680 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0349,551,411 - 49,641,517 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4340,191,727 - 40,260,488 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1340,088,098 - 40,156,860 (-)NCBI
Celera341,046,965 - 41,113,654 (-)NCBICelera
Cytogenetic Map3q21NCBI
ACVR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2157,736,251 - 157,876,330 (-)EnsemblGRCh38hg38GRCh38
GRCh382157,736,446 - 157,876,330 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372158,592,958 - 158,732,842 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362158,301,207 - 158,403,036 (-)NCBINCBI36hg18NCBI36
Build 342158,418,468 - 158,520,298NCBI
Celera2152,206,070 - 152,344,336 (-)NCBI
Cytogenetic Map2q24.1NCBI
HuRef2150,478,249 - 150,616,526 (-)NCBIHuRef
CHM1_12158,598,894 - 158,738,243 (-)NCBICHM1_1
Acvr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39258,336,450 - 58,456,840 (-)NCBIGRCm39mm39
GRCm39 Ensembl258,278,656 - 58,457,169 (-)Ensembl
GRCm38258,446,438 - 58,566,828 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl258,388,644 - 58,567,157 (-)EnsemblGRCm38mm10GRCm38
MGSCv37258,298,849 - 58,419,239 (-)NCBIGRCm37mm9NCBIm37
MGSCv36258,261,824 - 58,331,545 (-)NCBImm8
Celera260,202,316 - 60,294,260 (-)NCBICelera
Cytogenetic Map2C1.1NCBI
Acvr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544915,640,230 - 15,708,694 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544915,587,958 - 15,706,432 (+)NCBIChiLan1.0ChiLan1.0
ACVR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B162,234,823 - 162,372,533 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B162,234,823 - 162,297,805 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B44,994,175 - 45,133,490 (-)NCBIMhudiblu_PPA_v0panPan3
ACVR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1363,743,257 - 3,818,659 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl363,744,163 - 3,818,652 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha363,880,162 - 4,006,562 (-)NCBI
ROS_Cfam_1.0363,865,484 - 3,991,973 (-)NCBI
UMICH_Zoey_3.1363,867,397 - 3,993,826 (-)NCBI
UNSW_CanFamBas_1.0363,927,214 - 4,053,637 (-)NCBI
UU_Cfam_GSD_1.0363,965,356 - 4,091,837 (-)NCBI
Acvr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303120,806,153 - 120,874,529 (-)NCBI
SpeTri2.0NW_00493646920,743,195 - 20,811,567 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACVR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1564,748,761 - 64,892,153 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11564,749,478 - 64,891,653 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21571,681,467 - 71,823,490 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ACVR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11043,139,396 - 43,281,024 (-)NCBI
ChlSab1.1 Ensembl1043,139,528 - 43,281,177 (-)Ensembl
Vero_WHO_p1.0NW_023666040156,293,920 - 156,435,319 (+)NCBI
Acvr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247327,929,997 - 8,004,235 (+)NCBI

Position Markers
BF401349  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2343,037,901 - 43,038,048 (+)MAPPER
Rnor_6.0344,491,716 - 44,491,862NCBIRnor6.0
Rnor_5.0349,610,697 - 49,610,843UniSTSRnor5.0
RGSC_v3.4340,250,254 - 40,250,400UniSTSRGSC3.4
Celera341,104,894 - 41,105,040UniSTS
RH 3.4 Map16742.8UniSTS
Cytogenetic Map3q21UniSTS
RH138112  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2342,982,660 - 42,982,786 (+)MAPPER
Rnor_6.0344,436,580 - 44,436,705NCBIRnor6.0
Rnor_5.0349,555,515 - 49,555,640UniSTSRnor5.0
RGSC_v3.4340,194,784 - 40,194,909UniSTSRGSC3.4
Celera341,050,022 - 41,050,147UniSTS
RH 3.4 Map3554.0UniSTS
Cytogenetic Map3q21UniSTS
Acvr1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2342,979,809 - 42,980,549 (+)MAPPER
Rnor_6.0344,433,728 - 44,434,467NCBIRnor6.0
Rnor_5.0349,552,663 - 49,553,402UniSTSRnor5.0
RGSC_v3.4340,191,932 - 40,192,671UniSTSRGSC3.4
Celera341,047,170 - 41,047,909UniSTS
Cytogenetic Map3q21UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3195176874Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3263142148562146Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)3600074851687917Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)3600074851687917Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31009408193415837Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31011931879772001Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)310639528127023997Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)310639528127023997Rat
731172Bp151Blood pressure QTL 1510.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31409041148562146Rat
12879849Bw180Body weight QTL 1800.037body mass (VT:0001259)body weight (CMO:0000012)31409041148562146Rat
12879850Cm91Cardiac mass QTL 910.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)31409041148562146Rat
12879851Cm92Cardiac mass QTL 920.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)31409041148562146Rat
12879852Cm93Cardiac mass QTL 930.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)31409041148562146Rat
12879853Am5Aortic mass QTL 50.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)31409041148562146Rat
12879854Kidm63Kidney mass QTL 630.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)31409041148562146Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)31802366463023664Rat
10450794Scl69Serum cholesterol level QTL 696.30.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32122380366223803Rat
10450804Scl70Serum cholesterol level QTL 704.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32122380366223803Rat
631685Bp118Blood pressure QTL 1183.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)32465522569655225Rat
631832Sach1Saccharin preference QTL 12.70.02consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)32813672845772990Rat
2313049Bss72Bone structure and strength QTL 722.60.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)32813672851687917Rat
2313076Bss74Bone structure and strength QTL 7420.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)32813672851687917Rat
2313079Bss73Bone structure and strength QTL 731.5tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)32813672851687917Rat
2313093Bmd77Bone mineral density QTL 772.20.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)32813672851687917Rat
2313101Bmd76Bone mineral density QTL 763.60.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)32813672851687917Rat
2302055Pia30Pristane induced arthritis QTL 303.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)32932171474321714Rat
9590286Uminl1Urine mineral level QTL 13.50.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)32968273274682732Rat
9590136Scort3Serum corticosterone level QTL 323.370.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)32968273274682732Rat
8552950Pigfal12Plasma insulin-like growth factor 1 level QTL 127.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)32968273274682732Rat
8694196Abfw2Abdominal fat weight QTL 216.580.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)32968273274682732Rat
8694386Bw159Body weight QTL 1594.520.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)32968273274682732Rat
1354590Despr11Despair related QTL 110.000031locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)32990825574908255Rat
2303593Gluco46Glucose level QTL 463blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)32990825574908255Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)330114912123700444Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)330846101172879276Rat
2301400Cm68Cardiac mass QTL 680.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)33110358972989078Rat
11565451Bw177Body weight QTL 1770.002body mass (VT:0001259)body weight (CMO:0000012)33110358972989078Rat
11565452Kidm57Kidney mass QTL 570.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)33110358972989078Rat
12879866Cm94Cardiac mass QTL 940.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)33110358972989078Rat
12879867Cm95Cardiac mass QTL 950.047heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)33110358972989078Rat
12879868Am6Aortic mass QTL 60.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)33110358972989078Rat
61356Bp37Blood pressure QTL 373blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)33213099777130997Rat
631647Bp122Blood pressure QTL 1226.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)33213099777130997Rat
1300169Bp177Blood pressure QTL 1772.96arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)33347735462922975Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)33347735481136227Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333477354108914061Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)334394121103141944Rat
10450813Scl74Serum cholesterol level QTL 745.80.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)33924839152182792Rat
10450852Stl33Serum triglyceride level QTL 333.40.05blood LDL triglyceride amount (VT:0010699)blood lipoprotein triglyceride level (CMO:0002685)33924839152182792Rat
10450816Scl75Serum cholesterol level QTL 754.40.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)33924839152182792Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)339248391140271184Rat
4889975Bmd81Bone mineral density QTL 814.3tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)33977324751687917Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)34042292185422921Rat
634317Bw117Body weight QTL 1173.58abdominal fat pad mass (VT:1000711)abdominal fat pad weight to body weight ratio (CMO:0000095)34052359354745780Rat
2302276Bw82Body weight QTL 824.32body mass (VT:0001259)body weight (CMO:0000012)34052359364880586Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)34052359392654473Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)34052359392654473Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)343295930108914061Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)343295930163640485Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)343295930163640485Rat

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir130arno-miR-130a-3pMirtarbaseexternal_infoMicroarrayFunctional MTI (Weak)18258830

Predicted Target Of
Summary Value
Count of predictions:701
Count of miRNA genes:261
Interacting mature miRNAs:322
Transcripts:ENSRNOT00000006963
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 33 20 19 19 1 2 66 31 33 11 1
Low 3 10 37 22 19 22 7 9 8 4 8 7
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_024486 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006234214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AY693390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC167754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FB745997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L19341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000006963   ⟹   ENSRNOP00000006963
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl344,432,479 - 44,522,930 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000087071   ⟹   ENSRNOP00000072326
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl344,432,471 - 44,501,115 (-)Ensembl
RefSeq Acc Id: NM_024486   ⟹   NP_077812
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2342,979,605 - 43,047,200 (-)NCBI
Rnor_6.0344,433,523 - 44,500,986 (-)NCBI
Rnor_5.0349,551,411 - 49,641,517 (-)NCBI
RGSC_v3.4340,191,727 - 40,260,488 (-)RGD
Celera341,046,965 - 41,113,654 (-)RGD
Sequence:
RefSeq Acc Id: XM_006234214   ⟹   XP_006234276
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0344,432,476 - 44,539,680 (-)NCBI
Rnor_5.0349,551,411 - 49,641,517 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008761864   ⟹   XP_008760086
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0344,432,476 - 44,529,465 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008761867   ⟹   XP_008760089
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2342,978,558 - 43,097,892 (-)NCBI
Rnor_6.0344,432,476 - 44,478,216 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017592054   ⟹   XP_017447543
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2342,978,558 - 43,056,626 (-)NCBI
Rnor_6.0344,432,476 - 44,510,332 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039105896   ⟹   XP_038961824
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2342,978,558 - 43,097,892 (-)NCBI
RefSeq Acc Id: XM_039105897   ⟹   XP_038961825
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2342,978,558 - 43,084,469 (-)NCBI
RefSeq Acc Id: XM_039105898   ⟹   XP_038961826
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2342,978,558 - 43,082,359 (-)NCBI
RefSeq Acc Id: XM_039105899   ⟹   XP_038961827
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2342,978,558 - 43,097,892 (-)NCBI
RefSeq Acc Id: XM_039105900   ⟹   XP_038961828
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2342,978,558 - 43,084,436 (-)NCBI
RefSeq Acc Id: XM_039105902   ⟹   XP_038961830
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2342,978,558 - 43,082,359 (-)NCBI
RefSeq Acc Id: XM_039105903   ⟹   XP_038961831
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2342,978,558 - 43,097,892 (-)NCBI
RefSeq Acc Id: XM_039105904   ⟹   XP_038961832
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2342,978,558 - 43,097,892 (-)NCBI
RefSeq Acc Id: XM_039105905   ⟹   XP_038961833
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2342,978,558 - 43,097,892 (-)NCBI
RefSeq Acc Id: XM_039105906   ⟹   XP_038961834
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2342,978,558 - 43,097,892 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_077812   ⟸   NM_024486
- Peptide Label: precursor
- UniProtKB: P80201 (UniProtKB/Swiss-Prot),   B3DM96 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234276   ⟸   XM_006234214
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008760086   ⟸   XM_008761864
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008760089   ⟸   XM_008761867
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017447543   ⟸   XM_017592054
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K2P7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000072326   ⟸   ENSRNOT00000087071
RefSeq Acc Id: ENSRNOP00000006963   ⟸   ENSRNOT00000006963
RefSeq Acc Id: XP_038961833   ⟸   XM_039105905
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038961831   ⟸   XM_039105903
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038961832   ⟸   XM_039105904
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038961824   ⟸   XM_039105896
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038961834   ⟸   XM_039105906
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038961827   ⟸   XM_039105899
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038961825   ⟸   XM_039105897
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038961828   ⟸   XM_039105900
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038961826   ⟸   XM_039105898
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038961830   ⟸   XM_039105902
- Peptide Label: isoform X1
Protein Domains
GS   Protein kinase

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620200 AgrOrtholog
Ensembl Genes ENSRNOG00000005033 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000006963 UniProtKB/Swiss-Prot
  ENSRNOP00000072326 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006963 UniProtKB/Swiss-Prot
  ENSRNOT00000087071 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:9089038 IMAGE-MGC_LOAD
InterPro Activin_recp UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GS_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TGFB_receptor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:79558 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:187367 IMAGE-MGC_LOAD
NCBI Gene 79558 ENTREZGENE
PANTHER PTHR23255 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Activin_recp UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pkinase_Tyr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TGF_beta_GS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Acvr1 PhenoGen
PRINTS ACTIVIN2R UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS51256 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART S_TKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00467 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K2P7 ENTREZGENE, UniProtKB/TrEMBL
  ACVR1_RAT UniProtKB/Swiss-Prot
  B3DM96 ENTREZGENE, UniProtKB/TrEMBL
  P80201 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-15 Acvr1  activin A receptor type 1  Acvr1  activin A receptor, type I  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-09 Acvr1  activin A receptor, type I  Acvr1  activin A receptor, type 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Acvr1  activin A receptor, type 1    activin type I receptor  Name updated 1299863 APPROVED
2002-08-07 Acvr1  activin type I receptor      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_function receptor for activin 724707
gene_physical_interaction may form a complex with type II activin receptors 724761