Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | RGD:1604561 | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of TANC1 mRNA | CTD | PMID:22079256 | 1,2-dimethylhydrazine | affects expression | ISO | RGD:1332359 | 6480464 | 1, 2-Dimethylhydrazine affects the expression of TANC1 mRNA | CTD | PMID:22206623 | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | RGD:1332359 | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | RGD:1332359 | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:1604561 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TANC1 mRNA | CTD | PMID:20106945, PMID:21632981 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TANC1 mRNA | CTD | PMID:34747641 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2, 6-dinitrotoluene affects the expression of TANC1 mRNA | CTD | PMID:21346803 | 3,4-methylenedioxymethamphetamine | increases expression | EXP | | 6480464 | N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of TANC1 mRNA | CTD | PMID:30071829 | aflatoxin B1 | decreases methylation | ISO | RGD:1604561 | 6480464 | Aflatoxin B1 results in decreased methylation of TANC1 gene | CTD | PMID:27153756 | all-trans-retinoic acid | increases expression | ISO | RGD:1604561 | 6480464 | Tretinoin results in increased expression of TANC1 mRNA, Tretinoin results in increased expression of TANC1 protein | CTD | PMID:21934132 more ... | all-trans-retinoic acid | multiple interactions | ISO | RGD:1332359 | 6480464 | [bisphenol F co-treated with Tretinoin] results in decreased expression of TANC1 mRNA | CTD | PMID:30951980 | antirheumatic drug | increases expression | ISO | RGD:1604561 | 6480464 | Antirheumatic Agents results in increased expression of TANC1 mRNA | CTD | PMID:24449571 | arsenous acid | increases expression | ISO | RGD:1604561 | 6480464 | Arsenic Trioxide results in increased expression of TANC1 protein | CTD | PMID:30093655 | benzo[a]pyrene | decreases expression | ISO | RGD:1332359 | 6480464 | Benzo(a)pyrene results in decreased expression of TANC1 mRNA | CTD | PMID:19770486 | benzo[a]pyrene | increases methylation | ISO | RGD:1332359 | 6480464 | Benzo(a)pyrene results in increased methylation of TANC1 intron | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | RGD:1604561 | 6480464 | Benzo(a)pyrene affects the methylation of TANC1 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | ISO | RGD:1604561 | 6480464 | Benzo(a)pyrene results in decreased methylation of TANC1 promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | RGD:1604561 | 6480464 | Benzo(a)pyrene results in decreased expression of TANC1 mRNA | CTD | PMID:20106945 more ... | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of TANC1 mRNA | CTD | PMID:21839799 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | RGD:1604561 | 6480464 | 7 more ... | CTD | PMID:19150397 | benzo[b]fluoranthene | decreases expression | ISO | RGD:1332359 | 6480464 | benzo(b)fluoranthene results in decreased expression of TANC1 mRNA | CTD | PMID:26377693 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TANC1 mRNA | CTD | PMID:25181051 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of TANC1 gene | CTD | PMID:28505145 | bisphenol A | increases expression | ISO | RGD:1604561 | 6480464 | bisphenol A results in increased expression of TANC1 mRNA | CTD | PMID:29275510 | bisphenol F | multiple interactions | ISO | RGD:1332359 | 6480464 | [bisphenol F co-treated with Tretinoin] results in decreased expression of TANC1 mRNA | CTD | PMID:30951980 | Brodifacoum | decreases expression | EXP | | 6480464 | bromfenacoum results in decreased expression of TANC1 protein | CTD | PMID:28903499 | bromobenzene | increases expression | EXP | | 6480464 | bromobenzene results in increased expression of TANC1 mRNA | CTD | PMID:32479839 | calcitriol | multiple interactions | ISO | RGD:1604561 | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of TANC1 mRNA | CTD | PMID:21592394 | calcitriol | decreases expression | ISO | RGD:1604561 | 6480464 | Calcitriol results in decreased expression of TANC1 mRNA | CTD | PMID:21592394 | carbamazepine | affects expression | ISO | RGD:1604561 | 6480464 | Carbamazepine affects the expression of TANC1 mRNA | CTD | PMID:25979313 | carbon nanotube | decreases expression | ISO | RGD:1332359 | 6480464 | Nanotubes, Carbon results in decreased expression of TANC1 mRNA | CTD | PMID:25554681 | cisplatin | decreases expression | ISO | RGD:1604561 | 6480464 | Cisplatin results in decreased expression of TANC1 mRNA | CTD | PMID:19561079 | copper atom | multiple interactions | ISO | RGD:1604561 | 6480464 | [Disulfiram binds to Copper] which results in increased expression of TANC1 mRNA | CTD | PMID:24690739 | copper(0) | multiple interactions | ISO | RGD:1604561 | 6480464 | [Disulfiram binds to Copper] which results in increased expression of TANC1 mRNA | CTD | PMID:24690739 | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of TANC1 mRNA | CTD | PMID:27523638 | diarsenic trioxide | increases expression | ISO | RGD:1604561 | 6480464 | Arsenic Trioxide results in increased expression of TANC1 protein | CTD | PMID:30093655 | dibutyl phthalate | increases expression | ISO | RGD:1332359 | 6480464 | Dibutyl Phthalate results in increased expression of TANC1 mRNA | CTD | PMID:21266533 | dioxygen | affects methylation | ISO | RGD:1332359 | 6480464 | Oxygen deficiency affects the methylation of TANC1 promoter | CTD | PMID:24205000 | dioxygen | increases expression | ISO | RGD:1332359 | 6480464 | Oxygen deficiency results in increased expression of TANC1 mRNA | CTD | PMID:24205000 | disulfiram | multiple interactions | ISO | RGD:1604561 | 6480464 | [Disulfiram binds to Copper] which results in increased expression of TANC1 mRNA | CTD | PMID:24690739 | dorsomorphin | multiple interactions | ISO | RGD:1604561 | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | affects methylation | EXP | | 6480464 | Doxorubicin affects the methylation of TANC1 gene | CTD | PMID:28962528 | entinostat | increases expression | ISO | RGD:1604561 | 6480464 | entinostat results in increased expression of TANC1 mRNA | CTD | PMID:27188386 | ethanol | affects expression | ISO | RGD:1332359 | 6480464 | Ethanol affects the expression of TANC1 mRNA | CTD | PMID:30319688 | ethyl methanesulfonate | increases expression | ISO | RGD:1604561 | 6480464 | Ethyl Methanesulfonate results in increased expression of TANC1 mRNA | CTD | PMID:23649840 | fipronil | increases expression | EXP | | 6480464 | fipronil results in increased expression of TANC1 mRNA | CTD | PMID:23962444 | formaldehyde | decreases expression | ISO | RGD:1604561 | 6480464 | Formaldehyde results in decreased expression of TANC1 mRNA | CTD | PMID:20655997 | formaldehyde | increases expression | ISO | RGD:1604561 | 6480464 | Formaldehyde results in increased expression of TANC1 mRNA | CTD | PMID:23649840 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of TANC1 mRNA | CTD | PMID:33387578 | mercury dibromide | increases expression | ISO | RGD:1604561 | 6480464 | mercuric bromide results in increased expression of TANC1 mRNA | CTD | PMID:26272509 | mercury dibromide | multiple interactions | ISO | RGD:1604561 | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TANC1 mRNA | CTD | PMID:27188386 | methyl methanesulfonate | increases expression | ISO | RGD:1604561 | 6480464 | Methyl Methanesulfonate results in increased expression of TANC1 mRNA | CTD | PMID:23649840 | nickel atom | decreases expression | ISO | RGD:1604561 | 6480464 | Nickel results in decreased expression of TANC1 mRNA | CTD | PMID:24768652, PMID:25583101 | panobinostat | multiple interactions | ISO | RGD:1604561 | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TANC1 mRNA | CTD | PMID:27188386 | panobinostat | increases expression | ISO | RGD:1604561 | 6480464 | panobinostat results in increased expression of TANC1 mRNA | CTD | PMID:26272509 | paracetamol | affects expression | ISO | RGD:1332359 | 6480464 | Acetaminophen affects the expression of TANC1 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | RGD:1604561 | 6480464 | Acetaminophen results in increased expression of TANC1 mRNA | CTD | PMID:22230336 | PCB138 | multiple interactions | ISO | RGD:1332359 | 6480464 | [2 more ... | CTD | PMID:25510870 | phenobarbital | increases expression | ISO | RGD:1332359 | 6480464 | Phenobarbital results in increased expression of TANC1 mRNA | CTD | PMID:19270015 | phenylmercury acetate | increases expression | ISO | RGD:1604561 | 6480464 | Phenylmercuric Acetate results in increased expression of TANC1 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | RGD:1604561 | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TANC1 mRNA | CTD | PMID:27188386 | pirinixic acid | multiple interactions | ISO | RGD:1332359 | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of TANC1 mRNA | CTD | PMID:19710929 | potassium chromate | decreases expression | ISO | RGD:1604561 | 6480464 | potassium chromate(VI) results in decreased expression of TANC1 mRNA | CTD | PMID:22079256 | potassium chromate | multiple interactions | ISO | RGD:1604561 | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of TANC1 mRNA | CTD | PMID:22079256 | SB 431542 | multiple interactions | ISO | RGD:1604561 | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | temozolomide | increases expression | ISO | RGD:1604561 | 6480464 | Temozolomide results in increased expression of TANC1 mRNA | CTD | PMID:31758290 | testosterone | multiple interactions | ISO | RGD:1604561 | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of TANC1 mRNA | CTD | PMID:21592394 | testosterone | decreases expression | ISO | RGD:1604561 | 6480464 | Testosterone results in decreased expression of TANC1 mRNA | CTD | PMID:21592394 | trichloroethene | increases methylation | EXP | | 6480464 | Trichloroethylene results in increased methylation of TANC1 gene | CTD | PMID:27618143 | trichostatin A | increases expression | ISO | RGD:1604561 | 6480464 | trichostatin A results in increased expression of TANC1 mRNA | CTD | PMID:24935251 | trimellitic anhydride | decreases expression | ISO | RGD:1332359 | 6480464 | trimellitic anhydride results in decreased expression of TANC1 mRNA | CTD | PMID:19042947 | triptonide | decreases expression | ISO | RGD:1332359 | 6480464 | triptonide results in decreased expression of TANC1 mRNA | CTD | PMID:33045310 | tris(2-butoxyethyl) phosphate | affects expression | ISO | RGD:1604561 | 6480464 | tris(2-butoxyethyl) phosphate affects the expression of TANC1 mRNA | CTD | PMID:29024780 | troglitazone | decreases expression | ISO | RGD:1332359 | 6480464 | troglitazone results in decreased expression of TANC1 mRNA | CTD | PMID:28973697 | urethane | increases expression | ISO | RGD:1604561 | 6480464 | Urethane results in increased expression of TANC1 mRNA | CTD | PMID:28818685 | valproic acid | affects expression | ISO | RGD:1604561 | 6480464 | Valproic Acid affects the expression of TANC1 mRNA | CTD | PMID:25979313 | valproic acid | multiple interactions | ISO | RGD:1604561 | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TANC1 mRNA | CTD | PMID:27188386 | valproic acid | increases expression | ISO | RGD:1604561 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References
References - curated
| 1. | Han S, etal., J Neurosci. 2010 Nov 10;30(45):15102-12. doi: 10.1523/JNEUROSCI.3128-10.2010. |
| 2. | Nonaka H, etal., Biochem Biophys Res Commun. 2008 Dec 12;377(2):573-8. doi: 10.1016/j.bbrc.2008.10.038. Epub 2008 Oct 18. |
| 3. | RGD automated data pipeline |
| 4. | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 5. | RGD automated import pipeline for gene-chemical interactions |
Genomics
